Lesion detection in mammogram

Based on Multiresolution Analysis

ƒ Under the guidance of,

Ms. S .Deivalakshmi

Presented by,
Sujay Pujari.
• Problem statement
• Work done up to review 1
• Feature extraction on ROI
• Modified Feature extraction on ROI
• Result
• References
 Problem statement:
• To detect and classify Lesion without human
intervention
• To use adaptive Threshold segmentation (local and
global) with Multiresolution analysis of wavelet
transform
• To extract shape based feature of segmented region
• To explore
p novel modified shape
p based feature
extraction for ROI.
 On 6th OCT

ROI (Lesion)

Feature Extraction
 Preprocessing &
Implemented
p algorithm
g (p
(part1))

F t
Feature Extraction
E t ti

Feature set 1) Not useful feature

set,
2)ANOVA coefficients
coefficients,
3)Means of grouping Benign
Ground truth variable canonical Or
Unified ANOVA
of data distribution function Malignant
classification
Segmented lesion ROI -org

Region
selection

19 shape
p base features

Statistical Feature set

classifier 32 benign
g
33 malignant
Shape
based
features

Ref :1,2,3
Univariate ANOVA classification

Ref 1
Tool:
SPSS 15
For windows
Proposed algorithm (part1)
Modified shape based
Original CA Ch
#1 #2 #3

Wavelet
Multiresolution
Db4
Level 1

ROI
Cdd
Cvd #5
#4
Not useful Features

Standardized Canonical
Discriminant Function Coefficients
 Result

Original 65 samples

BLUE-
Original group
classification rate

Selected 48 samples

RED-
Cross validated
classification
rate
Ref:
1. B. Surendiran, A. Vadivel, Y. Sundaraiah," Classifying Digital Mammogram Masses
Using Univariate ANOVA Discriminant Analysis", ARTCom 2009, IEEE computer
society,(2009).
( )
2. A. Rojas and A. Nandi, Detection of masses in mammograms via
statistically based enhancement, multilevel-thresholding segmentation, an
region selection,
selection Comp Med Imag eGraphics 32 (2008) pp 304 304–315.
315
3. Gonzalez RC, Woods RE, Eddins SL. Digital image processing
using MATLAB. New Jersey, USA: Prentice Hall; 2004.

Tools and support

Thank
You
Implemented algorithm (part1)
Preprocessed Mammogram

Scale 1,LL channel

Histogram

Smoothing(moving average)

second derivative

Threshold=first Zero crossing

Im2Bw

Mask
 Ref
Kai Hu, Xieping Gao and Fei Li ”Detection of Suspicious Lesions by Adaptive
Thresholding Based on Multiresolution Analysis in Mammograms IEEE
TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, “ apr-2010

X. P
X P. Zh
Zhang anddM
M. D
D. D
Desai,i “S
“Segmentation
t ti off bright
b i ht ttargets
t using
i
wavelets and adaptive thresholding,” IEEE Trans. Image Process., vol. 10,
no. 7, pp. 1020–1030, Jul. 2001.

By Jelena Bozek,
Bozek Mario Mustra,
Mustra Kresimir Delac,
Delac and Mislav Grgic ,”A
A Survey of Image
Processing Algorithms in Digital Mammography”, Sig. Process. and Commun., SCI
231, pp. 631–657.springerlink 2009

G. Kom,
G Kom A. A Tiedeu,
Tiedeu and MM. Kom,
Kom “Automated
Automated detection of masses
in mammograms by local adaptive thresholding,” Comput. Biol. Med.,
vol. 37, no. 1, pp. 37–48, Jan. 2007.
Introduction to Wavelets and Wavelet Transforms
Transforms, A Primer –
PH 1997 - C Sidney Burrus, Ramesh A Gopinath, Haitao Guo
Mammogram databases:
http://cobweb.ecn.purdue.edu/~ace/mammo/mammo_
db.html