DRUG STUDY

NAME AND DOSE, MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING

CLASSIFICATION FREQUENCY ACTION S EFFECT RESPONSIBILITY
OF DRUG ROUTE,
DURATION OF
ADMINISTRATION
 Capsules  Reduces gastric  Gastroesophag  Long-term use for CNS: dizziness, ● Assess vital signs.
Generic Name: (delayed- acid secretion eal reflux gastroesophageal headache, ● Check for abdominal pain,
Omeprazole release): 40 mg and increases disease reflux disease, asthenia emesis, diarrhea, or
Brand Name: P.O , daily for gastric mucus  Erosive duodenal ulcers GI: nausea, constipation.
2 weeks and bicarbonate esophagitis vomiting, ● Evaluate fluid intake and
Classification: production,  Short-term diarrhea, output.
Pharmacologic class: creating treatment of constipation, ● Watch for elevated liver
Proton pump protective active abdominal pain function test results (rare).
inhibitor coating on duodenal ulcer Metabolic: ● Tell patient to take 30 to 60
Therapeutic class: gastric mucosa  To reduce risk hypomagnesemi minutes before a meal,
Antiulcer drug and easing of duodenal a preferably in morning.
discomfort from ulcers caused Musculoskeletal ● Instruct patient to swallow
excess gastric by : back pain; capsulesor tablets whole and
acid. Helicobacter fractures of hip, not to chew or crush them. If
pylori wrist, spine he can’t swallow capsule, tell
(with long-term him he may open it, carefully
daily use) sprinkle and mix entire
Respiratory: contents into 1 tbsp of cool
cough, upper applesauce, and swallow
respiratory tract immediately with glass of
infection water.
Skin: rash

Probiotics are
Generic Name: Capsule 1 cap P.O. Helps restore intestinal Promotion of general Use is also not advised in considered to be ●Monitor consistency of the
Gastro Flora daily microflora with good wellness and normal patients at risk of relatively safe. stool
Probiotics bacteria to maintain intestinal function. opportunistic infections Studies using
normal GUT health. and in those with badly probiotics have
Classification: damaged GI tracts. reported
Supplement/Adjunctiv abdominal
e therapy cramping,
nausea, fever,
soft stools,
flatulence, and
taste
disturbances.

Significant: Throm
Generic Name:  Tablet 500 mg P.O.4- a central analgesic Mild to moderate pain Hypersensitivity. Severe bocytopenia, ● Assess vital signs.
Pacetamol 6 hourly effect that is mediated and fever hepatic impairment or leucopenia,
through activation of active liver disease (IV). neutropenia,
Classification: descending pancytopenia,
Analgesics (Non- serotonergic pathways. methaemoglobinae
Opioid) & Debate exists about its mia,
Antipyretics primary site of action, agranulocytosis,
which may be angioedema, pain
inhibition of and burning
prostaglandin (PG) sensation at inj site.
synthesis or through an Rarely, hypotension
active metabolite and tachycardia.
influencing Gastrointestinal
cannabinoid receptors. disorders: Nausea,
vomiting,
constipation.
Nervous system
disorders: Headach
e.
 Psychiatric
disorders: Insomnia
.
Skin and
subcutaneous tissue
disorders: Erythem
a, flushing, pruritus.

Tablet 0.4 mg  Acts as

Generic Name: P.O.daily for a week competitive  Excessive GI ● Hypersensitivity to ●Assess vital signs and
Hyoscine-N- inhibitor at motility and scopolamine, other neurologic,
butylbromide postganglionic hypertonia in belladonna alkaloids,or cardiovascular,and respiratory
Brand Name: muscarinic irritable bowel barbiturates status.
Buscopan receptor sites of syndrome,mild ●Obstructive GI disease ● Monitor patient for urinary
parasympathetic dysentery,diver (including paralytic ileus hesitancy or retention.
Classification: nervous system ticulitis,pyloro and intestinal atony)
Pharmacologic class: and on smooth spasm ● Ulcerative colitis or toxic ●As appropriate,review all
Antimuscarinic, muscles that megacolon other significant adverse
belladonna alkaloid respond to reactions and
Therapeutic class: acetylcholine interactions,especially those
Antiemetic,antivertigo but lack related to the drugs,herbs,and
agent,anticholinergic cholinergic behaviors mentioned above.
innervation.Ma
y block
cholinergic
transmission
from vestibular
nuclei to higher
CNS centers
and from
reticular
formation to
vomiting center.
 Disturbs DNA
Tablets: 500 mg Po , synthesis in susceptible CNS:
Generic Name: daily bacterial organisms  Amebiasis ● Heart rate below 45 drowsiness,dizzines ● Advise patient to report
Metronidazole  Bacterial beats/minute, s,confusion, fever, sore throat,bleeding,or
Brand Name: infections second- or third-degree restlessness,fatigue bruising.
Flagyl IV heart block, CV: ● Advise patient to take drug
Classification: significant first-degree tachycardia,palpitat with food if it causes GI
Pharmacologic class: heart block; systolic ions,hypotension,tr upset.However,instruct him to
Nitroimidazole pressure below 100 mm ansient heart rate take extended-release tablets 1
derivative Hg; or changes EENT: hour before or 2 hours after
Therapeutic moderate-to-severe cardiac blurred meals
class:Anti-infective, failure vision,mydriasis,ph
antiprotozoal otophobia,conjuncti
vitis GI:
constipation,dry
mouth GU: urinary
hesitancy or
retention Skin:
decreased
sweating,rash

a prodrug of thiorphan,
Generic Name: 100 mg P.O. for 7 an enkephalinase CNS:
Racecadotril days until 2 formed inhibitor. It achieves its  Acute diarrhea Significant: Angioedema. dizziness,headache, ●Monitor consistency of the
stool is recorded antisecretory effect by Respiratory, thoracic and ataxia,vertigo,incoo stool
Brand Name: protecting enkephalins mediastinal rdination,insomnia, ● Evaluate fluid intake and
Hidrasec from enzymatic disorders:  Tonsillitis. EENT: output.
degradation thereby Skin and subcutaneous rhinitis,sinusitis,pha
Classification: prolonging their action tissue disorders: Rash, ryngitis
Antidirrheals at enkephalinergic erythema, urticaria, GI:
synapses in the small erythema multiforme, nausea,vomiting,dia
intestine and reducing nodular erythema, papular rrhea,abdominal
hypersecretion. rash, prurigo, pruritus. pain,furry
Potentially Fatal: Skin tongue,glossitis, dry
reactions. mouth,anorexia
GU: dysuria,dark
urine,incontinence
Hematologic:
leukopenia
Skin:
rash,urticaria,burni
ng,mild skin
dryness,skin
irritation,transient
redness (with
topical forms)