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Chenghua Sui, Shengjie Wo, Pinggen Cai, Nan Gao, Danyang Xu, Yonghao
Han & Chunnian Du
To cite this article: Chenghua Sui, Shengjie Wo, Pinggen Cai, Nan Gao, Danyang Xu, Yonghao
Han & Chunnian Du (2017) Design and implementation of optical system for Placido-disc
topography, Journal of Modern Optics, 64:21, 2413-2419, DOI: 10.1080/09500340.2017.1366567
Article views: 28
Download by: [Australian Catholic University] Date: 03 October 2017, At: 03:59
Journal of Modern Optics, 2017
VOL. 64, NO. 21, 2413–2419
https://doi.org/10.1080/09500340.2017.1366567
of corneal surface topography, an optical system for the corneal topography that is based on a KEYWORDS
Placido disc is designed, which includes a ring distribution on a Placido disc, an imaging system Optical design; corneal
and a collimating illumination system. First, a mathematical model that is based on the corneal topography; Placido disc;
topography working principles is established with MATLAB to determine the distribution of white- imaging lens
and-black rings on the Placido disc, in which the ellipsoid facial rings-target of the Placido disc is
utilized. Second, the imaging lens structure is designed and optimized by Zemax software. Last,
the collimating illumination lens structure is designed by paraxial ray trace equations. The quality
of the corneal topography, which is based on our designed optical system, is evaluated. The high-
contrast image of uniformly distributed white-and-black rings is observed through the CCD camera.
Our optical system for the corneal topography has high precision, with a measuring region of the
cornea with a diameter of approximately 10 mm. Therefore, the creation of this optical system offers
guidance for designing and improving the optical system of Placido-disc topography.
Figure 1. Schematic diagram of projection system of Placido- Figure 2. Mathematical first imaging model of Placido disc. Arc
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disc topography. The black-and-white concentric rings are on BAC is a cross section of Placido disc, in which A is a point in a
the Placido disc, white for the light transmission part, black for ring, B is a position of the centre hole and C is the endpoint of
the opaque part. LED back light source is on the backside of the the rings-target on the Placido disc. Semicircle with radius OD
Placido disc. A lens imaging system is installed in the centre of the represents the cornea. A′ is the virtual image of A after corneal
Placido disc. reflection.
which white rings enable light transmission and black the Placido disc due to its excellent measurement accu-
rings comprise the opaque part. A small hole is located racy and low processing requirement. Referring to the
in the centre of the Placido-disc rings-target for placing domestic and foreign patents and operations manual, we
the lens imaging system. After the light is emitted by the employed the 24-ring ellipsoid Placido disc to achieve
LED back light source on the backside of the Placido disc, high precision and repeatability and reduce the process-
the black-and-white rings on the Placido disc are pro- ing costs (11,12).
jected onto the patient’s cornea, and the rings are viewed To determine the rings distribution on the Placido
as a reflection of the cornea through the imaging lens to disc, we established a mathematical model by MATLAB
an image on a CCD camera. In the case of no pathological to resolve it. The cornea can act as a convex mirror, as
changes on the corneal surface, the reflection rings are shown in Figure 2. Arc BAC that is a cross section of the
equally spaced symmetric concentric circles. If the cor- Placido disc can be imaged by corneal refection. A′ is a vir-
neal surface is astigmatic and irregular, the rings will be tual image of A at a ring on the Placido disc that is imaged
distorted. Closer rings indicate higher curvature in the according to the convex mirror imaging principle as:
region of the cornea, which is similar to the terrain con- 1 1 1 2( )
tour measurement method (8). Therefore, the changes of − = � = p<0 ,
p q f r (1)
corneal curvature at different locations can be estimated
by analysing the deformation degree of concentric rings where p = AD is the object distance, q = DA′ is the image
on the image (9). distance, and f ′ and r are the focal length and radius of
spherical mirror, respectively. We assume
√ that the coordi-
3. Design of optical system nate of point A is (x, y); thus, p = r − x 2 + y 2. Inserting
it into Equation (1) to obtain:
3.1. Determination of the rings distribution on the √
Placido disc 2
r − r x2 + y2
General Placido-disc topographies include differ-
q= √ (2)
2 x2 + y2 − r
ent rings-targets: conical, planar and ellipsoid (10).
Compared with these three types, a conical rings-target
has a substantially larger number of rings with high meas- After assuming that the coordinate of point A′ is (x0, y0),
uring precision and a high machining accuracy require- the relation between the coordinate (x0, y0) and (x, y) exists
ment, whereas a planar rings-target has fewer rings with as:
simple processing, a small measuring range and low accu- x0 x
racy. In this paper, we chose the ellipsoid rings-target for y0
= .
y (3)
JOURNAL OF MODERN OPTICS 2415
�
⎛ 2 ⎞
⎜ r − r x2 + y2 ⎟ y
y0 = ⎜r − � ⎟� . (5)
⎜ 2 2
2 x +y −r ⎠ x +y ⎟ 2 2
⎝
Figure 4. Schematic diagram of the image projection (a) and the distribution of the rings in Placido disc (b).
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Figure 5. The side (a) and front (b) views of Placido disc in Solidworks.
The corneal horizontal diameter and vertical diame- Table 1. Optic specifications of the given system.
ter of Asian adults are approximately 11.0 and 10.0 mm, Parameter Value
respectively. According to the daily diagnosis experience, Operating Distance 75.0 mm
the required measurement coverage of the corneal surface Focal length 20.0 mm
Image height 2.8 mm
exceeds 9.3 mm (13). Thus, the operating distance of the Resolution 67.0 lp/mm
apparatus cannot be too long or too short. We designed it Aperture 6.5 mm
Object height 6.0 mm
as 75.0 mm to guarantee an adequate measurement range
of the cornea. The aperture stop of the imaging lens is the
centre hole in the Placido disc, whose diameter is 6.5 mm quality on the axis and near axis, we primarily focus on
[Table 1]. Thus, the imaging system consists of a small reducing the primary spherical aberration, coma, and axial
field of view and small relative aperture. We choose tradi- and lateral chromatic aberration rather than high-order
tional symmetric achromatic lenses, as the lens doublet can aberrations. After a series optimization by Zemax soft-
reduce axial and transverse chromatic aberrations and cor- ware, the final imaging lens system structure is shown in
rect spherical aberration and coma. To ensure the imaging Figure 6, in which the system’s focus is 20.01 mm, the
JOURNAL OF MODERN OPTICS 2417
Figure 6. Imaging lens structure obtained from final optimization. Different colours represent the imaging paths with different object
heights.
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Figure 7. MTF curves (a) and spot diagram (b) of imaging lens. The black line in Figure 7(a) indicates that the maximum theoretically
possible contrast that can be achieved is almost 85% at the 67.0 lp/mm frequency. Additionally, the four coloured lines correspond to
how the imaging lenses perform at the height of 0 mm (blue), 1.50 mm (yellow), 2.00 mm (red) and 5.00 mm (green). The corresponding
spot diagram of these four points is shown in Figure 7(b). The root-mean-square (RMS) and geometry (GEO) radius are 3.658 and 6.440
µm, respectively, at the height of 0 mm; 2.964 and 6.129 µm at the height of 2.00 mm; 3.238 and 6.445 µm at the height of 1.50 mm; and
4.877 and 10.859 µm at the height of 5.00 mm.
back-operating distance is 19.20 mm, the tube length is Then, a single LED lamp was employed as a point source
17.84 mm and the image height is 2.8 mm [Table 1]. to emit a bundle of light rays. The light rays passed the
To evaluate the quality of our designed imaging system, lens set and became the parallel light rays to illuminate
the MTF curves and spot diagram have been calculated by the half reflecting and half transparent mirror. For the lens
the theory according to the parameters (see Table 1) of the set, we combined a positive lens with a negative lens to
imaging system, as shown in Figure 7. The MTF curves reduce the length of the system and took a reverse design.
have been calculated on full field and paraxial field over For convenience, the lens was assumed to be a thin lens
a frequency range from 0 lp/mm to 67.0 lp/mm [Figure and was fabricated by the frequently employed glass K9.
7(a)]. The MTF value is greater than 0.5 at 33.5 lp/mm and As shown in Figure 8, the parallel incident light passes
is approximately 0.4 at 67.0 lp/mm. This indicates that our through lenses and focuses on one point according to
designed imaging system has high resolution and contrast. PRTE as (14)
The spot diagram is employed to evaluate situations of
n� u� = nu − y𝜙, (12)
astigmatism, coma, spherical aberration and chromatic
aberration. Observing the spot diagram [Figure 7(b)], the yj+1 = yj + u� d, (13)
root mean squares (RMS) of dispersion spot sizes of four
points are smaller than the CCD pixel size of 7.4 μm. All where n and n′ are the media refractive index of the object
dispersion spot sizes are similar to the Airy spot, which space and image space; here, they are both 1. u and u′
indicates that the system has high resolution for imaging are the respective incident and exit angles. y is the height
and the image is in focus. between incident light and optic axis, in which the sub-
script j represents the j-th refraction. ϕ is the focal power
of lens. d is the distance between two lenses. According
3.3. Lens design for collimating illumination system
to Equations (12) and (13), we can obtain:
{
To precisely align the imaging lens and the human eye
y2 = y1 + u1� d1
along an ideal straight line, we added a half reflecting and ,
u1� = u1 − y1 𝜙1 (14)
half transparent mirror at the back of the imaging lens.
2418 C. SUI ET AL.
When we performed a ray tracing calculation to obtain the 4. Experimental results and discussion
size parameters of the lens set, the values of parameters y1, After processing the imaging lens and collimating illu-
u1, d1 and d2 were set first. Then, ϕ1 and ϕ2 are calculated mination lens, we assembled them into an integral whole
with known y1, u1, d1 and d2. For easy processing, one side imaging system, as illustrated in Figure 10, in which part
of the positive and negative lenses were fabricated into a is the collimating illumination lenses (see Figure 9) and
the plan; thus, they were plane convex and plane concave part b is the imaging lenses (see Figure 6). To verify the
lenses (Figure 9). Their curvature radii can be obtained quality of our imaging system, the imaging lens’ optic
according to Equation (16) characteristics are measured by Image Master®Universal,
( ) which is produced from Germany Tropics. The corre-
( ) 1 1
𝜙1(2) = n1 − 1 − , (16) sponding MTF curve was measured on a paraxial field
r1(3) r2(4) and full field with a frequency range from 0 lp/mm to 70.0
lp/mm, as shown in Figure 11. The MTF value is greater
ϕ1(2) represents ϕ1 and ϕ2, r1(3) and r2(4) are the curvature than 0.5 at 33.5 lp/mm and greater than 0.3 at 67.6 lp/mm,
radii for the curved surfaces in the plane convex lens which is consistent with the results of our simulation test
and the plane concave lens, respectively, and n1 is the in Figure 7(a). Therefore, the excellent imaging resolution
refractive index of the glass. After the optimization with of the imaging system can be proven.
Zemax, Figure 9 shows the structure of the collimating The whole imaging system and Placido disc were assem-
illumination lens system that is composed of a negative bled into the integral instrument, as shown in Figure 12(a).
lens, a positive lens and a half reflecting and half trans- The instrument was tested on the human eye and an artifi-
parent mirror. cial eye by adjusting the cross hair at the centre of the cornea
JOURNAL OF MODERN OPTICS 2419
Figure 12. The whole machine system (a) and the corneal topographies for artificial eye (b) and human eye (c).
and (c), the black-and-white imaging rings of the Placido This work was supported by the National Science Foundation
disc that were reflected from the human eye and the artificial (NSF) [grant number 11604295]; Zhejiang Provincial Nat-
eye were equally spaced symmetric concentric circles with ural Science Foundation of China (ZJNSFC) [grant number
high contrast, high resolution and sharp edges. The reflected LQ17C100002]; Educational Commission of Zhejiang Prov-
rings are circular and perfectly and uniformly spaced, which ince of China [grant number Y201636360].
indicates that the cornea is a spherical surface. The image
taken by our system has high quality. Actually,the corneal References
vertex may deviate from the optical axis of optic system
(1) Lou, Q.; Wang, Y.; Wang, Z.; Liu, Y.; Zhang, L.; Fang, H.
during the normal shooting. In our system, the collimating
Appl. Opt. 2015, 54, 7490–7493.
illumination lens system has been designed to reduce the (2) Swartz, T.; Marten, L.; Wang, M. Curr. Opin. Ophthalmol.
deviation. Moreover, the deviation can be further reduced 2007, 18, 325–333.
by making a correction in subsequent image processing. (3) Huang, J.; Savini, G.; Hu, L.; Hoffer, K.; Lu, W.; Feng, Y.;
Therefore, our system can be used to diagnose the patient Yang, F.; Hu, X.; Wang, Q. J. Cataract Refract. Surg. 2012,
by tracing the photographed rings. 39, 219–224.
(4) Kawamorita, T.; Uozato, H.; Kamiya, K.; Bax, L.; Tsutsui,
K.; Aizawa, D.; Shimizu, K. J. Cataract Refract. Surg.
5. Conclusions 2009, 35, 127–133.
(5) McNabb, R.; Farsiu, S.; Stinnett, S.; Izatt, J.; Kuo, N.;
In this paper, an optical system for corneal topography based Huang, D. Ophthalmology. 2015, 122, 677–686.
on the Placido disc was designed, including the rings dis- (6) Karnowski, K.; Kaluzny, B.; Szkulmowski, M.; Gora, M.;
Wojtkowski, M. Biomed. Opt. Express. 2011, 2, 2709–
tribution on the Placido disc rings-target, imaging lens and
2720.
collimating illumination lens. First, 24 rings on the ellipsoid (7) He, Y.; Wang, Y.; Wang, Z.; Wang, Y.; Liu, Y.; Zhang, L.;
Placido disc was determined using MATLAB software. Then, Zhai, Y.; Chang, S. Appl. Opt. 2013, 52, 8532–8539.
the imaging lens structure was designed and optimized by (8) Rabinowitz, Y.; McDonnell, P. J. Cataract Refract. Surg.
Zemax software. Last, the collimating illumination lens was 1989, 5, 400–408.
designed by PRTE. Imaging the Placido ring reflections of (9) Wilson, S.; Klyce, S. Surv. Ophthalmol. 1991, 35, 269–277.
(10) Fowler, C.; Dave, T. Ophthalmic Physiol. Opt. 1994, 14,
the human eye and artificial eye has proven that high-quality 49–58.
images can be taken by our instrument. Additionally, our (11) Carbonari, K.J. Placido Projector for Corneal Topography
optical system has the advantages of simple structure, small System; US 7611245 B2, 2009.
size, easy processing and low cost. Therefore, our design has (12) Giannozzi, F.; Spadini, S. Led Light Placido Disc Projector
practical value in the design and improvement of the corneal for a Corneal Topography System; US 0289758 A1, 2015.
(13) Zadnik, K.; Friedman, N.; Mutti, D. J. Cataract Refract.
topography based on the Placido disc.
Surg. 1995, 11, 119–125.
(14) Geary, J.M. Introduction to Lens Design with Practical
Disclosure statement Zemax Examples; Willmann-Bell Inc:Richmond,
Virginai, USA, 2002; p 50.
No potential conflict of interest was reported by the authors.