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3 Nutritional Challenges in Special Conditions and Diseases

Koletzko B, et al. (eds): Pediatric Nutrition in Practice. World Rev Nutr Diet. Basel, Karger, 2015, vol 113, pp 163–167
DOI: 10.1159/000360331

3.5 Management of Child and Adolescent Obesity


Louise A. Baur

Key Words Clinical Assessment


Obesity · Children · Adolescents · Assessment ·
Management Clinical history should aid in assessing current
and potential future comorbidities as well as
modifiable lifestyle practices (table 1) [1–4]. The
Key Messages BMI [weight (kg)/height (m)2], a clinically useful
• The BMI [weight (kg)/height (m)2] should be plotted measure of body fatness in those aged >2 years,
routinely on a BMI-for-age chart should be plotted on nationally recommended
• The principles of obesity management include: BMI-for-age charts [5], e.g. the WHO Child
management of comorbidities; family involvement;
Growth Standards. However, the cutoff points
a developmentally appropriate approach; the use
used to define overweight and obesity are some-

3
of a range of behavior change techniques; long-
term dietary change; increased physical activity, what arbitrary and may vary between countries.
and decreased sedentary behaviors For example, in the UK the cutoff points for over-
• Orlistat may be useful as an adjunct to lifestyle weight and obesity are the 91st and 98th percen-
change for more severely obese adolescents, and tiles, respectively, compared with the 85th and
metformin for adolescents with clinical insulin re- 95th in the USA. Hence, local recommendations
sistance
• Bariatric surgery should be considered with severe-
should be checked. A waist circumference-to-
ly obese adolescents height ratio of >0.5 is associated with increased
• Coordinated models of care for health service deliv- cardiometabolic risk in school-aged children [6].
ery are needed for the management of pediatric Waist circumference-for-age charts are available
obesity © 2015 S. Karger AG, Basel for some countries.
Physical examination is used to assess obesity-
associated comorbidities as well as signs of un-
Introduction derlying genetic or endocrine disorders (table 2).
The level of investigation is dependent on the pa-
Child and adolescent obesity is a prevalent prob- tient’s severity of obesity and age, the clinical
lem in most westernized and rapidly westernizing findings and associated familial risk factors.
countries and is associated with both immediate Baseline investigations may include fasting lipid
and longer-term complications. Effective treat- screening, glucose, liver function tests and, pos-
ment of those affected by obesity is vital. sibly, insulin [1–4]. Second-line investigations
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Table 1. Elements of history-taking in obese children and adolescents

General history Prenatal and birth – history of gestational diabetes and birth weight
Infant feeding – duration of breastfeeding
Current medications – glucocorticoids, some antiepileptics and
antipsychotics
Weight history Onset of obesity and duration of parental and child concerns about
their weight
Previous weight management interventions
Previous and current dieting behaviors
Complications Psychological – bullying, poor self-esteem, depression
history Sleep – snoring, symptoms suggestive of sleep apnea
Exercise tolerance
Specific symptoms related to gastroesophageal reflux, gallstones,
benign intracranial hypertension, orthopedic complications,
enuresis, constipation
Menstrual history (girls)
Family history Ethnicity
Family members with a history of: obesity, type 2 diabetes,
gestational diabetes, cardiovascular disease, dyslipidemia,
obstructive sleep apnea, polycystic ovary syndrome, bariatric
surgery, eating disorders
Lifestyle history Diet and eating behaviors – breakfast consumption, snacking,
fast-food intake, beverage consumption, family routines around
food, binge eating, sneaking food
Sedentary behavior – daily screen time; numbers of televisions,
gaming consoles, computers and smart phones in the bedroom
and home; pattern of screen time
Physical activity – after school and weekend recreation, sports
participation, transport to and from school, family activities
Sleep – duration and routines

may include liver ultrasound, an oral glucose tol- mean BMI reduction of 1.25 to 1.30 when com-
erance test, more detailed endocrine assessment pared with no treatment or usual care [8]. The
and polysomnography. longer the duration of treatment, the greater the
weight loss observed [8]. Lifestyle interventions
also lead to improvements in low-density lipo-
Treatment Strategies protein cholesterol, triglycerides, fasting insulin
and blood pressure up to 1 year from baseline [8].
Systematic reviews of pediatric obesity treatment Some of the challenges of treatment are that
show that lifestyle interventions can lead to im- ‘real-world’ obesity clinics are often more poorly
provements in weight and cardiometabolic out- resourced than in clinical trials, and clinic pa-
comes [7, 8]. While there is no evidence to sup- tients may be more socially disadvantaged, or
port one specific treatment program over anoth- have a broader range of comorbidities, than those
er, meta-analyses show that family-targeted who take part in trials, making treatment adher-
behavioral lifestyle interventions can lead to a ence more difficult.
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164 Baur
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Koletzko B, et al. (eds): Pediatric Nutrition in Practice. World Rev Nutr Diet. Basel, Karger, 2015, vol 113, pp 163–167
DOI: 10.1159/000360331
Table 2. Physical examination of obese children or adolescents and important physical findings [9, 11]

Organ system Physical findings

Skin/subcutaneous Acanthosis nigricans, skin tags, hirsutism, acne, striae, pseudogynecomastia (males),
tissues intertrigo, xanthelasmas (hypercholesterolemia)
Neurological Papilledema and/or reduced venous pulsations on funduscopy (pseudotumor cerebri)
Head and neck Tonsillar size, obstructed breathing
Cardiovascular Hypertension, heart rate (cardiorespiratory fitness)
Respiratory Exercise intolerance, wheeze (asthma)
Gastrointestinal Hepatomegaly and hepatic tenderness (nonalcoholic fatty liver disease), abdominal
tenderness (secondary to gallstones or gastroesophageal reflux)
Musculoskeletal Pes planus, groin pain, and painful or waddling gait (slipped capital femoral epiphysis),
tibia vara (Blount disease), lower-limb arthralgia and restriction of joint movement
Endocrine Goiter, extensive striae, hypertension, dorsocervical fat pad, pubertal staging, reduced
growth velocity
Psychosocial Flat affect and low mood, poor self-esteem, social isolation
Other – evidence of Short stature, disproportion, dysmorphism, developmental delay
a possible underlying
genetic syndrome

However, the broad principles of management A Developmentally Appropriate Approach


are well recognized [1–4, 7, 8]: management of For preadolescent children, weight outcomes
obesity-associated comorbidities; family involve-
ment; a developmentally appropriate approach;
long-term behavior modification; dietary change;
may be improved with a parent-focused interven-
tion, without direct engagement of the child [9].
There are more limited data on the treatment of
3
increased physical activity; decreased sedentary adolescent obesity than on younger children, and
behaviors; a plan for longer-term weight mainte- especially on interventions that would be sustain-
nance strategies; and consideration of the use of able in most health care settings. Generally, pro-
pharmacotherapy and other nonconventional vision of at least some separate therapist session
therapies. time with the adolescent seems appropriate.

Behavior Modification
Elements of Treatment Weight outcomes are improved with the use of a
broader range of behavior change techniques [1–
Family Focus 4]. One such technique, goal-setting, can include
Many clinical trials show that family-based inter- performance goals (such as changing eating or ac-
ventions can lead to long-term relative weight tivity behaviors) or outcome goals (such as spe-
loss, i.e. from 2 to 10 years. Parental involvement cific weight loss). Examples of the former include
when managing obese preadolescent children ap- not buying cookies, or reducing television time to
pears vital, although there are more limited data 3 h per day. Another technique, stimulus control,
on management of adolescents. refers to modifying or restricting environmental
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Management of Child and Adolescent Obesity 165


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Koletzko B, et al. (eds): Pediatric Nutrition in Practice. World Rev Nutr Diet. Basel, Karger, 2015, vol 113, pp 163–167
DOI: 10.1159/000360331
influences in order to aid weight control, with ex- While most people with obesity do not have a
amples including not eating in front of the televi- binge eating disorder, the latter is more common
sion, or using smaller plates and bowls within the in people with severe obesity. Further, overweight
home. A third commonly used technique, self- adolescents are more likely to binge-eat, and child-
monitoring, involves the recording of a specific hood obesity is a risk factor for later bulimia. How-
behavior or outcome, such as the use of a food di- ever, professionally run pediatric obesity programs
ary, daily pedometer measurement of physical ac- do not increase the risk of disordered eating and
tivity, or weekly weighing. may improve psychological wellbeing [10].

Dietary Change and Eating Behaviors Physical Activity and Sedentary Behaviors
Treatment programs incorporating a dietary In clinical practice, increased physical activity
component can be effective in achieving relative may best result from a change in incidental, or un-
weight loss in children and adolescents, although planned, activity, such as by walking or cycling
no one dietary prescription appears superior to for transport, undertaking household chores and
another [8]. However, dietary interventions are playing. Organized exercise programs have a role,
usually part of a broader lifestyle change pro- with children and adolescents being encouraged
gram, and are rarely evaluated on their own. The to choose activities that they enjoy and which are
two most commonly reported diets are: (a) the sustainable. Limiting television and other small-
modified stop/traffic light approach, where foods screen recreation to less than 2 h per day is par-
are color-coded on the basis of nutritional value ticularly strategic, but may be challenging [11].
and energy content to indicate those to be eaten Parental involvement is vital and may include
freely (green) or more cautiously (amber, red), monitoring and limiting television use, role-mod-
and (b) a calorie restriction/hypocaloric diet ap- eling of healthy behaviors, and providing access to
proach. Both diets can lead to sustained weight recreation areas or recreational equipment.
loss across different settings and age groups [8].
The role of dietary macronutrient modification in Long-Term Weight Maintenance
the management of obese children and adoles- In those who undergo an initial weight manage-
cents remains unclear. ment intervention, a period of further therapeutic
In general, dietary interventions should follow contact appears to slow weight regain [12]. At
national nutritional guidelines and have an em- present, there is limited evidence to guide the na-
phasis on the following [1–3]: ture and type of long-term weight maintenance
• Regular meals interventions.
• Eating together as a family
• Choosing nutrient-rich foods which are lower
in energy and glycemic index Nonconventional Therapies
• Increased vegetable and fruit intake
• Healthier snack food options There is relatively limited evidence to guide the
• Decreased portion sizes use of less orthodox treatment approaches such as
• Drinking water as the main beverage very-low-energy diets, pharmacological therapy
• Reduction in sugary drink intake or bariatric surgery in treating severe pediatric
• Involvement of the entire family in making obesity. Such therapies should occur on the back-
sustainable dietary changes ground of a behavioral weight management pro-
In advising patients and families on dietary chang- gram and be restricted to specialist centers with
es, is there a risk of an eating disorder developing? expertise in managing severe obesity.
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166 Baur
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Koletzko B, et al. (eds): Pediatric Nutrition in Practice. World Rev Nutr Diet. Basel, Karger, 2015, vol 113, pp 163–167
DOI: 10.1159/000360331
Existing recommendations on management of Health Service Delivery Issues
pediatric obesity suggest that drug therapy (large-
ly orlistat, a gastrointestinal and pancreatic lipase Given the high prevalence and chronicity of pedi-
inhibitor) can be used in the treatment of severely atric obesity, there is a need for coordinated mod-
obese adolescents, in the context of a tertiary care els of care for health service delivery. One poten-
protocol provided by a multidisciplinary care tial approach, the chronic disease care model, is
team and incorporating continued diet and activ- based upon a tiered level of service delivery relat-
ity counseling [1–4]. For obese, insulin-resistant ing to disease severity [16]. Thus, while most peo-
adolescents there may be a role for the use of met- ple affected by the problem of obesity can be man-
formin, an insulin-sensitizing agent [13]. aged via self-care or family-based care, with sup-
The few consensus guidelines for bariatric sur- port from primary care or community-based
gery in adolescents have highlighted its use in se- health service providers, there is a need for treat-
verely obese adolescents, with consideration of the ment by multidisciplinary care teams, and possi-
adolescent’s decisional capacity and attainment of bly tertiary care clinics, for those who are more
physical maturity, as well as the presence of a sup- severely affected. Individual clinicians should be
portive family environment [1, 3, 4, 14, 15]. The aware of the presence of other services within
need for management in centers with multidisci- their geographic region, and the capacity of these
plinary weight management teams, for the surgery to take referrals or to comanage patients.
to be performed in tertiary institutions experi-
enced in bariatric surgery and for long-term mul-
tidisciplinary follow-up has been emphasized.

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Management of Child and Adolescent Obesity 167


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Koletzko B, et al. (eds): Pediatric Nutrition in Practice. World Rev Nutr Diet. Basel, Karger, 2015, vol 113, pp 163–167
DOI: 10.1159/000360331

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