VISHWAKARMA INSTITUTE OF

TECHNOLOGY

Name :- Jaideep Kulkarni

Roll No: - 46
GR No: - 1710844

NANOTECHNOLOGY

EXPERIMENT No: - 1

To review synthesis methods of metal and metal oxide

nanoparticles; and applications of nanotechnology in
healthcare.
 Experiment :- 1
➢ Aim:-
To review synthesis methods of metal and metal oxide nanoparticles; and
applications of nanotechnology in healthcare.

➢ Synthesis of metal and metal oxide nanoparticles (Zinc):-

Sr. Method of Precursor Characterizati Stabilizing Conclusions/Results

no. Synthesis on techniques agent/Capping
agent
1 Whey Zn(NO3)2.6H2O XRD, TEM, Citric acid ZnO nanoparticles size
assisted Raman 18-89 nm. Absorbance
sol-gel Spectroscopy, at 315-340nm.
method UV-Vis Crystalline.
2 Green Zn(NO3)2.6H2O FTIR, TEM, Punicagranatum 10-30 nm ZnO particle
Synthesis FESEM, XRD leaf extract as size.
reducing agent Potential for
photocatalytic
degradation.
3 Reduction ZnO UV-Vis, XRD, Cinnamon as 340 nm absorbance of
method EDX, SEM capping agent Zn Nps
Hexagonal wurtzite
4 Homogeno ZnCl2 and FTIR, SEM, 1)1,2 ethane- Absorbance 315-400 nm
us phase NaOH TEM, BET diol Zn nanoparticles
reaction 2)2-propanol
5 Laser ZnO plates TEM, XRD, Aq. Starch Smaller nanoparticles as
ablation FTIR compared to distilled
water.
Applications in
biomedical sector.
 ➢ Applications of Nanotechnology in healthcare (Literature survey): -

Sr no. Diseases Nanoparticles Safety issues/ Advantages of

cured/Applications used limits using
nanoparticles
1 Sunscreen TiO2 1.Upto 25% Spread ability
TiO2permitted. improves.
2.Size>100 nm
2 Cancer cell Carbon - Early stage
detection in blood nanotubes detection
stream
3 Detection of Gold nanorods - Shift in colour due
Kidney damage to presence of
proteins which
indicates damage
4 Drug delivery Gold 1.Gold: Long circulatory
nanoparticles size>100 nm targeted delivery
and Liposomes 2.Liposomes: possible
size = 50-200
nm
5 Tumor Iron 100-400 nm Solid dosage
nanoparticles through nano-
capsulation
6 Antibacterial and Silver 1.Highest Better uptake of
antifungal nanoparticles toxicity above Ag nanoparticles
medicines 25 ppm. by cells as
2.Protein compared to micro
denaturation at size particles.
high
concentration.
3.Mitochondrial
disfunctioning.
7 Cosmetics ZnO, Ag Size: 60-120 Cosmetic creams
nanoparticles nm are transparent and
If liposome nearly invisible
covering is and better
absent it can screening in case
cause side of sunscreens.
effects
8 Imaging Silver and Iron - Increases
oxide efficiency of MRI,
nanoparticles Ultrasound and
Optical scanners.

9 Capsules or matrix Polymeric nano - To maintain

particles delivery
 therapeutic level of
drug
10 They are used in Quantum dots - In biological
computic , material
photovoltalic
devices