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# COH 315: Epidemiology

Midterm Exam

## MAXIMUM 150 points

Calculations: Answer the following questions in the space provided. Show all of your work.

(5 points each)

1. Calculate the attack rate for those who ate potato salad using the data in Table 1.

ATE DIDN’T EAT

## Item consumed Sick Well Sick Well

Potato salad 80 10 90 30
Potato chips 70 25 35 70

## 80/90 or 0.89 or 89%

2. Calculate the incidence rate of SARS in Shanghai in 2004 using the data in Table 2.

## (137 / 16,740,000) x 1,000,000 = 8.18 per 1 million

3. Calculate the prevalence rate of hypertension in the US in 2000 using the data in Table 3.

## (375,000 + 65,000,000 / 300,000,000) x 100 = 21.7 Per 100

4. Calculate the annual death rate from all causes for Tanzania in 2005 using the data in Table 4.

## (28,000 / 40,000,000) x 1,000,000 = 700 per Million

5. Calculate the specific death rate due to malaria in Tanzania in 2005 using the data in Table 4.

## (8,000 / 40,000,000) x 1,000,000 = 200 per Million

6. Calculate the proportionate mortality rate due to HIV/AIDS in Tanzania in 2005 using the data in
Table 4.

## (4,000 / 28,000) x 1,000 = 142.86 per 1,000

7. Calculate the case fatality rate for prostate cancer for the year 2008 using the data in Table 5.

## Table 5. Prostate Cancer

New diagnoses 2007-2008 alive 1 year after diagnosis alive 5 years after diagnosis

## (50 / 6,500) x 100 = 76%

8. Calculate the age-adjusted rate of osteoporosis in Tuscany and Naples using the direct method
and data in Table 6.

## Table 6. Osteoporosis in Tuscany and Naples

Age Standard Pop. Tuscany pop. Tuscany rate per 1000 Naples Pop. Naples rate per 1000

## Naples = 92,500 / 1,300,000 = 92.5 / 1,300 or 0.07 = 70 per 1,000

9. Calculate the sensitivity of the screening test for alcoholism using the data in Table 7.

Negative 40 480

## 160 / (160 + 40) = 0.80 or 80%

10. Calculate the specificity of the screening test for alcoholism using the data in Table 7.

## 480 / (480 + 320) = 0.60 or 60%

11. Calculate the percentage of false negatives of the screening test for alcoholism using the data in
Table 7.

## 40 / (40 + 160) = 0.2 or 20%

12. Calculate the percentage of false positives of the screening test for alcoholism using the data in
Table 7.
320 / (480 + 320) = 0.4 or 40%

13. Calculate the positive predictive value of the screening test for alcoholism using the data in
Table 7.

## 160 / (160 + 320) = 0.33 or 33%

14. Calculate the probability of surviving 5 years using the data from Table 8.

P1 = 52.5%

P2= 46.1%

P3 = 65.5%

P4= 69.6%
P5 = 80.0%

P6 = 95%

P7 = 98%

## (52.5%) x (46.1%) x (65.5%) x (69.6%) x (80.0%) = 8.83%

15. Calculate the power of a study given that the probability of a type I error is 0.05 and the
probability of type II error is 0.80.

1 – 0.80 = 0.2