Blood Bank Homework

1- The presence of Anti-A1 is usually detected by?

2- What is acquired B Phenomena?

3- Give ABO typing. A patient whose blood is a subgroup of A gives the following red cell

reactions when tested against various antisera:

Reactions of patient's RBCs Antisera

Negative Dolichos biflorus
Mixed field agglutination Anti-A
Mixed field agglutination Anti-AB

4- Give the most likely cause for the ABO forward and reverse reactions given below:

Reverse grouping Forward grouping

O cells B cells A1 cells Anti-A,B Anti-B Anti-A
0 0 0 +4 0 +4

5- Based on the following red cell reactions: C+, D+, E+, c+, e+, the only Rh genotype that is not a

possibility is?

6- The major immunoglobulin class(es) of anti-A in a group B individual is/are:

7- What are the possible ABO phenotypes of the offspring from the mating of a group AB to a

group B individual?

8- The sugar responsible for blood group A specificity is:

9- While the sugar responsible for the H substance specificity is:

10- Ulex europaeus Lectin is an:

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11- What ABH substance(s) would be found in the saliva of a group B secretor:

12- Which ABO blood groups contains the least amount of the H substance:

13- What antigen is found in 85% of the white population and is always significant for transfusion

purposes:

14- The normal ABO blood group which have usually a characteristic anti-H in their sera:

15- How are Rh antigens inherited?

16- The ABO typing of a patient's sample yield the following results:

Reverse grouping Forward Grouping

B cells A1 cells Anti-B Anti-A
+3 0 0 +4
The patient's ABO blood group is:

17- A patient has the phenotype O, CDEe. If transfused with blood from six random group O,

Rh(D) positive donors, the patient could theoretically produce which Rh antibody:

18- Order the antigenisity of the 5 Rh antigens?

19- The most important immunoglobulin type in Blood Banking that may cause HDN and HTR is:

20- The following reactions are obtained on ABO testing of patient's blood sample. What is the

most likely ABO group?

Reverse grouping Forward grouping

O cells B cells A2 cells A1 cells Lectin A1 Anti-A,B Anti-B Anti-A
0 +4 0 +2 +2 +3 0 +3
21- Cold antibody could be defined as:

22- What factors influence the physical attachment of antibodies to RBC antigens:

23- Naturally occurring antibodies could be defined as:

24- The ABO group of the following results is:

Reverse grouping Forward Grouping

B cells A1 cells Anti-B Anti-A
+4 +4 0 0
25- What naturally occurring antibodies are found in the sera of Oh phenotype people:

26- What reagents should be used to resolve an A subgroup with anti-A1:

27- What antibodies could R1r' individual make if exposed to R2r'' blood?

28- Given the reactions below, the patient's ABO group is:

Reverse grouping Forward grouping

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 B cells A1 cells Rh control Anti-D Anti-A,B Anti-B Anti-A
+4 0 0 +3 +4 0 +4
29- Zeta potential refers to the:

30-The following reactions were obtained by testing RBCs from a donor unit with

antisera:

Anti-D: 0

Anti-C: +

Anti-E: +

Anti-c: 0

Anti-e: +

1. What Rh antigens does the donor possess? (2 points)

2. What is the phenotype? (2 points)

3. Determine genotype? (2 points)

4. What antibodies could this donor make if he were to be transfused? (2 points)

5. Is this phenotype rare or common? (2 points)