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Quality of Life Research

https://doi.org/10.1007/s11136-020-02493-7

Factors associated with social isolation in community‑dwelling older


adults: a cross‑sectional study
Reshma A. Merchant1,3   · Shumei Germaine Liu1 · Jia Yi Lim3 · Xiaoxi Fu1 · Yiong Huak Chan2

Accepted: 26 March 2020


© Springer Nature Switzerland AG 2020

Abstract
Purpose  Social isolation in older adults is a major public health problem and associated with increased morbidity and mor-
tality. There are limited data on the association between social isolation and physical function including gait speed. Hence,
this study is to determine the prevalence of social isolation and its association with gait speed, frailty, cognition, depression
and comorbidities amongst community-dwelling older adults.
Methods  Social isolation, depression, frailty and perceived general health were assessed using 6-item Lubben Social Network
Scale (LSNS-6), Geriatric Depression Scale (GDS), FRAIL scale and EuroQol EQ-5D-5L questionnaire which includes EQ
Visual Analogue Scale (EQ-VAS), respectively. Cognition was assessed using the Chinese Mini Mental State Examination
(cMMSE), while physical performance test included gait speed and short physical performance battery test. Binary logistic
regression was performed to determine the influence of socio-demographic, medical, functional and cognitive variables on
social isolation.
Results  Out of 202 participants, 27.7% were robust, 66.8% of participants were pre-frail, and 5.4% of participants were
frail. Almost half (45.5%, n = 92) of the participants were found to be at risk of social isolation. A poor social network was
negatively associated with mean gait speed (OR = 0.674, CI 0.464–0.979, p = 0.039), EQ-VAS (OR = 0.561, CI 0.390–0.806,
p < 0.01) and cMMSE (OR = 0.630, 95% CI 0.413–0.960, p = 0.032).
Conclusion  Almost half of older adults in the community are at risk of social isolation with a very significant association
with gait speed, cMMSE and EQ-VAS scores.

Keywords  Social isolation · Older adults · Gait speed · Quality of life

Introduction 65 years and above in Singapore accounts for 13.7% of the


total population, and will double by 2030 [2]. Singapore is
The world’s population is ageing especially in Asia where ranked third in global life expectancy ranking [3]. Commu-
the number of persons aged 60 years and older is grow- nities that facilitate healthy ageing in place are increasingly
ing faster than all younger age group [1]. Older adults aged relevant in meeting these needs, especially with a growing
trend of older adults preferring to live in their own homes
Electronic supplementary material  The online version of this and communities, even if this means living alone [4, 5].
article (https​://doi.org/10.1007/s1113​6-020-02493​-7) contains In addition to being healthy and enabling an individual to
supplementary material, which is available to authorized users. age in place, strong social networks have a direct impact on
health and well-being, with studies showing an association
* Reshma A. Merchant
reshmaa@nuhs.edu.sg with increased quality of life [6] and a protective effect on
cognition and the development of dementia [7]. Conversely,
1
Division of Geriatric Medicine, Department of Medicine, social isolation in older adults has been shown to increase
National University Hospital, 1E Kent Ridge Road, hospital readmission, disease morbidity and mortality rates
Singapore 119228, Singapore
[8, 9]. It has been debated that effect of social isolation on
2
Biostatistics Unit, Yong Loo Lin School of Medicine, mortality is comparable to quitting smoking and exceeds
National University of Singapore, Singapore, Singapore
many well-known risk factors such as obesity and physi-
3
Department of Medicine, Yong Loo Lin School of Medicine, cal inactivity [10]. Older adults are particularly at risk for
National University of Singapore, Singapore, Singapore

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Quality of Life Research

social isolation and poor social network due to retirement, using the Lubben Social Network Scale (LSNS-6). Func-
mobility limitation, age related physiological changes such tional status was assessed using the Lawton IADL Scale [25]
as vision and hearing impairments and increasing ill health. and perceived general health was assessed using EuroQol
International institutions such as World Health Organization EQ-5D-5L questionnaire which comprises the EQ-5D-5L
(WHO) have flagged social isolation as a key social and pol- descriptive system and EQ Visual Analogue Scale (EQ-
icy issue for ageing [11, 12]. There are numerous initiatives VAS) [26–28].
in place to address social isolation, and many countries are The 5-item FRAIL scale [24] has been extensively vali-
now looking into the age-friendly cities (AFC) and commu- dated locally and in numerous populations across various
nities movement promoted by WHO. Such AFCs are adapted continents and in different settings [29, 30]. The FRAIL
in various ways, for example, built-environment, to support scale is comparable in terms of function with the multidi-
the daily needs of the ageing population while promoting mensional deficit accumulation frailty index in predicting
active ageing [13]. physical limitations and mortality [31]. The scores range
Social isolation and loneliness while related are two from 0 to 5, where scores of 3–5 represent frail and 1–2 pre-
separate constructs. Social isolation can be defined objec- frail. Fear of falling (FOF) was identified by asking “Are you
tively as having either reduced number of social contacts afraid of falling?’ [32]. For those who replied yes, they were
and frequency of interactions or subjectively as feeling iso- asked to choose between somewhat or very much afraid of
lated or low quality interactions. Loneliness is a state of falling. Depression was assessed using the Geriatric Depres-
emotion which is evaluated subjectively [14] and can result sion Scale (GDS) and cognition was assessed using the Chi-
from perceived social isolation [15, 16]. A myriad of fac- nese Mini Mental State Examination (cMMSE).
tors have been found to be associated with social isolation The only dependent variable, risk of social isolation, was
in old age; these includes low socioeconomic status [17], measured using the 6-item Lubben Social Network Scale
poor health status [18], impaired mobility [19, 20] as well as (LSNS-6). LSNS-6 is a brief, validated instrument devel-
cognitive function [21, 22]. Amongst these factors, decline oped to measure social isolation in older adults including
in gait speed has been found to be reversible by commonly size, closeness and frequency of contact with friends and
used exercise interventions [23]. While there have been family members and correlates with self-perceived health
an increasing number of studies looking at social isola- and physical activity limitations [33]. The total scale score
tion in older adults, there are limited data on association ranges from 0 to 30 obtained by summing the six items and
with physical measures including gait speed, frailty, medi- a score below 12 suggests at risk of social isolation. LSNS-6
cal comorbidities and cognition. This cross-sectional study has been validated in Asian populations including Malaysia,
aims to determine the prevalence of social isolation amongst China, Japan and Korea [15, 34].
community-dwelling older adults and its association with Following the interview, participants were invited to take
physical function including gait speed and frailty, cogni- part in several physical performance tests which were admin-
tion and comorbidities. Identifying such associations is of istered by trained staff. These tests were carried out in the
high importance for preventive measures to be implemented neighbourhood community centre or senior activity centres.
before other health aspects are implicated. Physical performance screening included body mass index
(BMI), 10 m gait speed with 1 m acceleration and decelera-
tion, body mass index, Snellen test over 3 m (impairment if
Methods at least one eye was worse than 6/18) and Short Performance
Physical Battery (SPPB) Test.
An observational cross-sectional study was performed of All statistical analyses were carried out using IBM
community-dwelling older adults aged 60 years and older. SPSS Statistics 25.0. Descriptive statistics for numerical
Recruitment of the seniors took place between August variables were presented as mean and standard deviations,
2017 and December 2018 through network of grassroots and frequencies and percentages for categorical variables.
volunteers, senior activity centres and words of peers who Mann–Whitney U test (for quantitative) and chi-square test
attended the screening program intended to identify sen- (categorical) were used to test for significant differences in
iors at risk, e.g. pre-frail, frail and those with cognitive demographics and health characteristics between those who
impairment. are at risk of social isolation and those who are not. Principle
The screening consisted of an interview questionnaire components (PCA) were derived for these medical, func-
and physical performance test. The interview questionnaire tional and cognitive variables (number of chronic disease,
included questions on socio-demographics, physical activ- cMMSE score, balance score, chair stand score, mean gait
ity, frailty using the FRAIL (Fatigue, Resistance, Ambu- speed, GDS score and perceived health rating) to resolve
lation, Illness, and Loss of Weight) scale [24], functional multi-collinearity issues (which will dilute the significance
status, chronic diseases, polypharmacy and social isolation of the variables) by creating uncorrelated surrogate variables

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Quality of Life Research

to be used together with socio-demographic in the binary LSNS-6 are shown in Annex 1. Three quarter (75.3%)
logistic regression to determine their influence on social of older adults hear from three or more friends a month
isolation in three models. Statistical significance was set at but 47.0% (n = 95) and 46.0% (n = 93) do not have any
p < 0.05. friends they feel at ease to talk about personal matters
Ethics approval was obtained from Domain-Specific or help them in difficulty, respectively. Significant differ-
Review Board of National Healthcare Group, Singapore. ences between those at risk and not at risk of social isola-
All participants provided signed consent. tion were only found for years of education and having at
least two IADL impairment. There was a non-significantly
higher prevalence of fear of falling in the older adults at
Results risk of social isolation,
Tables 2 and 3 show factors associated with risk of
A total of 202 community-dwelling older adults partici- social isolation. After adjusting for participants’ charac-
pated in the study. As shown in Table 1, 158 (78.2%) of the teristics in Table 1 and confounding factors in Table 2, gait
participants were female. The mean age of participants was speed, cMMSE and EQ-VAS scores in Model 3 which had
74.1 years. Participants reported an average of five years a marginal good fit with p = 0.078 (chi-sq = 12.1, df = 8)
of education and approximately one in every five partici- remained significantly associated with risk of social iso-
pants (18.8%) was living alone. Most of the participants in lation. Older adults with slower gait speed were at 1.5
this study were pre-frail (66.8%, n = 135) or robust (27.7%, times risk of social isolation (adjusted OR = 0.674, CI
n = 56), with only 5.4% (n = 11) of participants being frail. 0.464–0.979) while those with lower EQ-VAS scores were
About one in four had a lot of fear for fall (26.7%), seven in at 1.8 times risk (adjusted OR = 0.561, CI 0.390–0.806).
ten (67.5%, n = 131) participants had vision impairment and Those with lower cMMSE scores have 37% increased like-
one in ten had at least two IADL impairment. lihood of being at risk of social isolation. For functional
Almost one in two (45.5%) participants were found status, while non-significant, those at risk of social isola-
to be at risk of social isolation. Individual responses to tion had lower balance and chair stand scores.

Table 1  Characteristics of All Not at risk of social At risk of social p value#


participants n = 202 isolation isolation
n = 110 (54.5%) n = 92 (45.5%)

Gender (female) 158 (78.2) 86 (78.2) 72 (78.3) 0.989


Age 74.1 ± 7.9 73.4 ± 7.9 75.0 ± 7.9 0.226
BMI 24.0 ± 4.3 24.3 ± 4.4 23.6 ± 4.2 0.250
Ethnicity* 0.668
 Chinese 181 (89.6) 97 (88.2) 84 (91.3)
 Malay 17 (8.4) 11 (10.0) 6 (6.5)
 Indian 4 (2.0) 2 (1.8) 2 (2.2)  < 0.01
Years of education 5.0 ± 4.5 5.7 ± 4.6 4.1 ± 4.2
Frailty status 0.444
 Robust 56 (27.7) 32 (29.1) 24 (26.1)
 Pre-frail 135 (66.8) 74 (67.3) 61 (66.3)
 Frail 11 (5.4) 4 (3.6) 7 (7.6)
A lot fear of falling 54 (26.7) 23 (20.9) 31 (33.7) 0.124
Living alone 38 (18.8) 19 (17.3) 19 (20.7) 0.224
Vision impairment 131 (67.5) 70 (64.2) 61 (71.8) 0.266
At least two IADL impairment 19 (9.4) 4 (4.5) 14 (15.2) 0.010

Bold indicates p < 0.05


SD standard deviation
IADL Instrumental Activities of Daily Living
Values are n (%), otherwise mean ± SD
*Ethnicity was self-reported

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Table 2  Unadjusted and adjusted odds ratio for factors associated with risk of social isolation
Factors All Not at risk of social At risk of social Unadjusted Model ­1+
n = 202 isolation isolation OR (95% CI)
n = 110 n = 92 p value

Gait speed 1.14 ± 0.3 1.21 ± 0.3 1.07 ± 0.28 0.172 (0.061–0.488) 0.256 (0.073–0.904)


p < 0.01 p = 0.034
SPPB Balance score 3.4 ± 1.0 3.5 ± 0.8 3.2 ± 1.1 0.732 (0.543–0.988) 0.859 (0.598–1.235)
p = 0.041 p = 0.413
SPPB Chair stand score 2.9 ± 1.2 3.1 ± 1.2 2.7 ± 1.3 0.772 (0.613–0.973) 0.871 (0.667–1.136)
p = 0.028 p = 0.307
cMMSE score 25.5 ± 3.7 26.2 ± 3.1 24.7 ± 4.1 0.886 (0.815–0.962) 0.884 (0.792–0.987)
p < 0.01 p = 0.028
GDS 1.7 ± 1.9 1.6 ± 2.0 1.8 ± 1.7 1.069 (0.920–1.242) 1.014 (0.856–1.201)
p = 0.385 p = 0.874
EQ-VAS 72.1 ± 15.2 75.6 ± 12.7 67.9 ± 16.9 0.966 (0.947–0.985) 0.965 (0.943–0.987)
p < 0.01 p < 0.01
Number of chronic diseases 1.6 ± 1.3 1.4 ± 1.1 1.8 ± 1.4 1.209 (0.969–1.507) 1.215 (0.957–1.542)
p = 0.092 p = 0.110

Bold indicates p < 0.05


GDS Geriatric Depression Score, SPPB Short Physical Performance Battery Test, cMMSE Chinese Mini Mental State Examination
Values are mean ± SD
+
 Odd ratios adjusted for variables in Table 1

Table 3  Adjusted odds ratio for factors associated with risk of social 26.2 to 49.8% [15, 35, 36]. Almost half of the older adults
isolation felt they had no friends they could talk about personal
Factors Model ­2* Model ­3^ matters (47.0%) with or help them in difficulty (46.0%).
Older adults with declining function tend to rely more on
Gait speed 0.672 (0.493–0.917) 0.674 (0.464–0.979) friends, family and society for support where meaningful
p = 0.012 p = 0.039
social contact is an important aspect of well-being and
SPPB Balance 0.866 (0.638–1.174) 0.874 (0.608–1.252)
p = 0.353 p = 0.460 ageing well [37].
SPPB Chair stand 0.837 (0.618–1.132) 0.892 (0.635–1.251) Data from this study indicate a strong association
p = 0.248 p = 0.507 between social isolation and gait speed. Slow gait speed
cMMSE score 0.625 (0.453–0.863) 0.630 (0.413–0.960) is a well-recognised predictor of poor clinical outcomes
p < 0.01 p = 0.032 in community-dwelling older adults [38, 39]. Gait speed
GDS mean 1.105 (0.819–1.490) 01.004 (0.721–1.397) is also a useful diagnostic tool for sarcopenia and frailty
p = 0.516 p = 0.983
[40]. Older adults who are able to ambulate more easily
EQ-VAS 0.594 (0.434–0.814) 0.561 (0.390–0.806)
in the community have more opportunity to engage with
p < 0.01 p < 0.01
friends and family [41]. A recent study published reported
Number of chronic 1.272 (0.940–1.720) 1.304 (0.949–1.793)
diseases p = 0.119 p = 0.102 that social isolation was associated with a decrease in gait
speed after 6 years, especially in participants from a lower
Bold indicates p < 0.05 social economic class [42]. Data from the same study of
*Model 2 adjusts each factor for the remaining factors within the 2817 older adults aged > 60 also showed that adults with
table
^
loneliness were more likely to become frail over time [43].
 Model 3 adjusts each factor for the remaining factors within the table
Although non-significant, our study did show a higher
as well as participants’ characteristics from Table 1
prevalence of frailty in those at risk of social isolation.
While interventions to reduce social isolation and lone-
Discussion liness including senior clubs, befriending initiatives and
psychosocial group have produced mixed results [44–48],
Findings from this study suggest that nearly one in every a recent intervention on membership of a fitness program
two community-dwelling older adults (45.5%) is at risk of did show reduction in social isolation and loneliness [49]
social isolation. The prevalence is similar to many other which further supports impact of function on social isola-
countries depending on the definition used ranging from tion. The importance of planning for appropriate physical
environments and age-friendly communities in developing

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Quality of Life Research

social networks and reducing the risk of social isolation of community-dwelling older adults who lack these social
cannot be understated [50]. connections, suggesting that the prevalence of older adults
Older adults at risk of being socially isolated had sig- with a poor social network could be even higher. Second, the
nificantly poorer scores on the self-rated EQ-VAS scale of cross-sectional nature of this study excludes the analysis of
general health. This corroborates the observation of Coyle causal relationships between social isolation and other physi-
and Dugan (2012) where the likelihood of rating one’s health cal and social participant characteristics. As such, whether
as fair/poor was as high as 39% for those who scored higher the association between gait speed and social isolation is
on the social isolation scale. Similar relationship was also bi-directional is unclear. Third, the gender ratio in this study
documented in other studies [15, 51, 52]. Social isolation population was skewed towards the female gender, with 4
increases the risk of being diagnosed with chronic illness female participants for every 1 male participant. Previous
[53]. In our study, older adults at risk of social isolation did studies suggest that men are more likely to be socially iso-
have a slightly higher numbers of chronic diseases although lated compared to women [60], suggesting again that the
it did not reach a significant level. The association between prevalence of socially isolated older adults is likely to be
social isolation and poor health is consistent with available higher than amongst our population.
literature across various adult age groups, including a meta- Opportunities for further research include other factors
analysis of 148 studies where participants with stronger that have not been discussed in this study, such as subjective
social networks were shown to have a 50% increased likeli- measures of loneliness, nutritional status and implications
hood of survival [10] and a systematic review of 128 papers on physical health including rate of hospital readmissions
[45] which showed that increased social isolation is con- and healthcare utilization. In addition to identifying individ-
sistently associated with poor cardiovascular health. The ual characteristics associated with social isolation in older
mechanisms and causal links through which increased dis- adults, further research is needed to understand broader bar-
ease morbidity is associated with poorer social networks is, riers to fostering a good social network, such as financial or
however, still being investigated, with suggestions that this environmental constraints including monetary concerns or
could be due to loneliness and depression. a lack of physical spaces to interact with friends or family.
There is evidence linking social isolation with cognition This would be important in aiding efforts at a population-
in later life [22, 34, 54, 55]. Our study also showed an over- based level to improve access to good social networks for
all lower cMMSE scores in those at risk of social isolation. older adults.
Most of the evidence above was in longitudinal follow-up
studies. Slow gait speed in those with mild cognitive impair-
ment which is better known as Motoric Cognitive Risk Syn-
drome (MCR) is also a predictor of incident dementia in Conclusion
later life [56].
There was non-significant difference between the GDS Social isolation is associated with many adverse outcomes
mean scores amongst those at risk and not at risk of social including dementia, poor mobility, disease morbidity and
isolation. This could be due to the overall prevalence of mortality. Almost half of older adults in the community are
depression amongst older adults in Singapore being low at at risk of social isolation with a very significant association
5% [57]. Many studies on the contrary have reported asso- with gait speed, cMMSE and EQ-VAS scores. Those at risk
ciation of social isolation with depression [58, 59]. had overall lower education attainment and higher preva-
The findings from this study are important for Age lence of at least two IADL impairment. The findings from
Friendly Community Planning Committee, social and this study are useful for future Age Friendly Community
healthcare policy makers to create supportive and acces- Planning Committee, and policy makers to create supportive
sible environments, public awareness, educational program and accessible environments, and build a sustainable com-
and effective intervention. While the other associations were munity health ecosystem. The impact of functional screen-
not significant, longitudinal studies did highlight the adverse ing with necessary interventions and enabling environment
consequences of social isolation including increased health- on social isolation needs to be studied in a larger population
care utilization, depression and dementia [7]. [57].
While this study represents overall community-dwelling
older adults, there are several minor limitations in this study.
First, the study population involved a group of community- Funding  Ministry of Health, Singapore.
dwelling older adults who likely had pre-existing contacts
with grassroots organisations, senior activity centres or a net- Compliance with ethical standards 
work of friends that enabled them to learn about participa-
Conflict of interest  The authors declare no conflict of interest.
tion in the study. This could lead to an under-representation

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Quality of Life Research

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