Trinity University of Asia

St. Luke’s College of Nursing

Batch Asperion 2013

Mina Maternity Lying-In Clinic

DRUG STUDY
2nu03 - Group 3

ESPIRITU, Anna Victoria

ESTABLECIDA, Jan Ydnnyl Sage

ESTOLAS, Meece Marie

EVANGELISTA, John Radge

FABELLON, Aima Mae

Clinical Instructor: Florence Somera
August 28, 2010
 Drug Study
Name of Drug Dosage Mode of Action Side Effects Nursing
Consideration
1. HYDRALAZINE Adults Therapeutic Action CNS
HYDROCHLORIDE  Oral Acts Directly on Headache
Start with 10mg qid vascular smooth Peripheral Neuritis,
PO for the first 2-4 muscle to cause Dizziness, Tremors,
days. Increase to 25mg vasodilation, primarily Psychotic reactions
qid PO for the first arteriolar, decreasing characterized by
week, 50mg qid for 2nd peripheral resistance, depression, disorientation
and subsequent weeks. maintains or increases or anxiety.
 Parenteral renal and cerebral CV
Hypertension : 20- blood flow. Palpitations, Tachycardia,
40mg IV or IM. Use Indications Angina Pectoris,
only when drug cannot  Oral Hypotension, Paradoxical
be given orally. Essential hypertension Pressors response,
Transfer to oral form alone or combination Orthostatic Hypotension.
as soon as possible. with other drugs GI
Eclampsia : 5-10mg  Parenteral Anorexia, Nausea,
every 20 minutes via Severe essential Vomiting, Diarrhea,
IV bolus. If no hypertension when Constipation, Paralytic
response after 20mg, drug cannot be given Ileus.
try another drug. orally or when needed GU
Pediatrics to lower BP is urgent. Difficult Micturition,
 Oral  Unlabelled Impotence
0.75mg/kg/day PO, Uses Hematologic
given in divided doses Reducing after load in Blood dyscrasias
every 6-12 hours. the treatment of heart Hypersensitivity
Dosage maybe failure, severe aortic Rash, Urticaria, Pruritus,
gradually increase insufficiency and after Fever, Chill, Arthralgia,
over the next 3- valve replacement. Eosinophilia; rarely,
 4weeks to a maximum (Doses up to 800mg hepatitis, obstructive
of 7.5mg/kg/day PO or tid) jaundice
200mg/day PO Other
 Parenteral Nasal congestion,
1.7-3.5mg/kg divided flushing, edema, muscle
into 4-6 dosage. cramps,
lymphadenopathy,
splenomegaly, dyspnea,
lupus-like syndrome,
possible carcinogenesis,
lacrimation,
conjunctivitis.
2. TRAHEXAMIC
ACID
3. OXYTETRACYCLI
NE
4. ERYTHROMYCI N Ophthalmic Therapeutic Actions Ophthalmic Ointment
BASE Ointment Bacteriostatic or  Dermatologic
 Adult and bactericidal in Edema, urticaria,
Pediatric susceptible bacteria; dermatitis, angioneurotic
Patients binds to cell edema
One half inch ribbon membrane, causing  Local
instilled into change in protein Irritation, burning, itching
conjunctival sac of function leading to at site of application
affected eye 2-6 times cell death.
per day depending on Indications
severity of infection. Ophthalmic Ointment
Treatment of
superficial ocular
infections caused by
susceptible strains of
microorganisms;
prophylaxis of
 ophthalmia
neonatorum caused by
N. gonorrhea or C.
trachomatis.
5. AMOXICILLIN Adults and pediatric Therapeutic Action CNS
TRIHYDRATE patients weighting Bactericidal: Inhibits Lethargy, hallucinations,
more than 40kg synthesis of cell wall seizures
URIs, GU infections, of sensitive organisms, GI
skin and soft tissue causing cell death. Glossitis, stomatitis,
infections: Mild to Indications gastritis, sore mouth,
moderate – 250mg PO  Treatment of furry tongue, black
every 8 hour – 500 mg tonsillitis and “hairy” tongue, nausea,
PO every 12 hour; pharyngitis vomiting, diarrhea,
severe infection – 500 caused by abdominal pain, bloody
mg every 8 hour or Streptococcus diarrhea, enterocolitis,
875 mg every 12 hour. pyogenes (ER pseudomembranous
tablet) colitis, non-specific
Post exposure anthrax  Infections due hepatitis
prophylaxis: 500 mg to susceptible GU
PO tid to complete a strains of Nephritis
60 day course after 14- Haemophilus Hematologic
21 days of a influenza, Anemia,
floroquinolone or Escherichia thrombocytopenia,
doxycycline. coli, Proteus leucopenia, neutropenia,
mirabilis, prolonged bleeding time
Lower respiratory Neisseria Hypersensitivity
infections: 500 mg PO gonorrhea, Rash, fever, wheezing,
every 8 hour or 875 Streptococcus anaphylaxis
mg PO bid pneumonia, Other
Enterococcus Super infections – oral
Uncomplicated faecalis, and rectal moniliasis,
gonococcal infections: Stretococcal, vaginitis
3 g amoxicillin with 1 Non-
g probenecid PO as a penicillinase-
single dose producing
Staphylococci
C. Trachomatis in  Helicobacter
pregnancy: 500 mg pylori infection
PO tid for 7 days or in combination
875 mg PO bid. with other
agents
Tonsilitis or  Post exposure
pharyngitis: 775 prophylaxis
mg/day PO for 10 against
days with food (ER Bacillus
tablet). anthracis
 Unlabeled use:
H. pylori infections: 1 Chlamydia
g bid with trachomatis in
clarithomycin 500 mg pregnancy,
bid and lansoprazole mild to
30 mg bid for 14 days. moderate otitis
media in
children