P. D.

HINDUJA NATIONAL
HOSPITAL AND MEDICAL
RESEARCH
S C CENTRE
C N
MUMBAI

Research Department
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 RESEARCH DEPARTMENT

´ The Research section of the hospital was

established in the year 1987
´ The section is actively involved in conducting
basic research, clinical research, and drug trials
´ It is
i recognized
i db by MMumbaib iU
University
i it ffor th
the
degrees of MSc & PhD by research in January
1993.
1993

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 RESEARCH DEPARTMENT

´ Our Laboratory Is fully accredited by the College

of American Pathologists [ CAP ]
´ Registration with Central Plan Schemes of the
Government of India, under Controller General
of Accounts (CGS),
(CGS) India.
India

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ORGANIZATION CHART

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 ETHICS & SCIENTIFIC COMMITTEE

´ Clinical Research Ethics Committee (CREC) :

´ Institutional Review Board (IRB)

´ National Advisory Committee

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 ETHICS & SCIENTIFIC COMMITTEE
´ CREC & IRB:
«Formulated as per ICMR guidelines
«Each EC meets once in two months (alternate
(
months)
«Meet additionally if required
«Institutional Review board (IRB) registered with
Office for Human Research Protections (OHRP) , US &
Federal Wide Assurance approval from OHRP
«New SOP’s formulated as per ICMR guidelines as well
as OHRP (US) guidelines.

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•There are 16 MSc/PhD seats. Students do high
qualityy research for their Universityy degree.
q g

•So far 55 students have registered

g for MSc and
PhD of Mumbai University.

•Of these 20 have obtained MSc degree, 11

have obtained PhD. 9 have submitted
synopsis/thesis.

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´ SSo ffar totall 584 projects
j h
have b
been submitted
b i d and
d many off them
h
have significantly contributed to our knowledge base.

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 STUDIES SUPPORTED BY NATIONAL AGENCIES

1. Ladyy Tata Memorial Trust ((LTMT))

2. Baba Atomic Research Center (BARC)
3. Center for Cellular & Molecular Biology, (CCMB)
Hyderabad.
4. Department
p of Biotechnologygy (DBT)
( )
5. ICMR : Dr. Manoj Chadha
6. Bombay Orthopedic Society: Dr Vikas Agashe

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 INTERNATIONAL COLLABORATIONS
´ National Institute Of Health ((NIH)) , U.S ggovernment,,
Health and Human Services (HHS)
´ Oxford University, UK
´ University college, London
´ Japanese Cardiology Association
´ American Heart Association
´ Canadian Association
´ FIND Diagnostics
´ Mc g
gill universityy

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 PARTICIPATION IN INTERNATIONAL STUDIES
´ Dr Jatin Kothari with American Heart Association grant on
study
d off Biomarkers
Bi k off kidney
kid injury
i j after
f cardiac
di surgery.
´ Dr. Z.F.Udwadia, with Imperial college London, UK for
'Biomarkers for immunity to MTB infection in exposed but
un infected healthcare workers'
´ Dr.F.N.Kapadia : inditiated by Ethics section of the European
Societyy of Intensive Care Medicine coordination with
Welpicus project on 'Consensus guidelines for world wide
End of Life Practice for patients in Intensive care units‘.
´ Dr Z F Udwadia with Menssana Research,Inc., New Jersey for
“Can a point‐of‐care breath test be used to diagnose active
pulmonary tuberculosis?”

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 PARTICIPATION IN INTERNATIONAL STUDIES

´ Dr C Rodrigues with Prof Tony Catanzaro, University of

California, San Diego, Rapid tests for drug resistance to detect
extensively drug resistant tuberculosis, NIH, USA grant.
´ Dr C Rodrigues
g with FIND diagnostics,
g , Geneva,, Switzerland for
“Evaluation of the FIND / Cepheid Xpert MTB assay for the
detection of pulmonary TB in sputum of symptomatic adults”.
´ Dr C Rodrigues with Dr.Madhukar
Dr Madhukar Pai,
Pai McGill University
University,
Canada for 'Evaluation of LED microscopy for TB diagnosis in
high incidence settings'.
´ Co ordination by the Canadian Intensive care association to
study patterns of weaning patients from invasive mechanical
ventilation – across the world by Dr F N Kapadia

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 PARTICIPATION IN INTERNATIONAL STUDIES

´ Dr C Rodrigues : with Prof Lazerange, University of St Louis,

Paris, on study of diagnosis of tuberculosis by ESAT6, CFP10,
PGL Antigen for diagnosis of Tuberculosis.
´ Dr T.F.Ashavaid
Dr. T F Ashavaid : Accurex India Pvt Ltd in collaboration with
Daiichi Pure Chemicals (Tokyo, Japan)
´ Dr Asha Pherwani collaborated with ISAAC-International
study of Asthma & Allergies in childhood
´ Dr Alan Almeida: 'Global renal information database'. The
GRID‐CKD
GRID CKD project
project. 'Evaluation
Evaluation of chronic kidney disease
practice patterns through the global information database
(GRID)

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 PROPOSED INTERNATIONAL STUDIES

´ Dr C Rodrigues with Prof Dalia Goletti, European

Union, to develop test to differentiate active
from latent TB

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 AREAS OF RESEARCH & DEVELOPMENT
A - Basic Sciences
• Molecular Biology
• Genetics
• Biochemistry
• Microbiology ‐ Infectious diseases – TB, HCV, HIV, HBV, etc
• Hematology,
gy transfusion medicine

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 AREAS OF RESEARCH & DEVELOPMENT
B - Clinical Sections
• Critical Care Medicine • Pediatrics
• Oncology • Neurosurgery
• Endocrinology and diabetics • Orthopedics
• Chest Medicine
• Infectious diseases
• Rheumatology
• Cardiology
• Gastroenterology
• Nephrology
• ENT
• Imaging
I i
• Ophthalmology
• Neurology (including pediatric neurology)

C - Clinical Trials ..Phase II & III studies.

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