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PATHOPHYSIOLOGY OF THE DISEASE

ANGINA PECTORIS

Predisposing factor:
Modifiable Predisposing Factor: Non
Modifiable
Stress
Age
Diet
Gender
Sedentary life style
Heredity
Smoking

Alcohol

Diabetes melitus

Obesity

Hypertension

Atherosclerosis

Fatty streaks,
lipids develop in
the arterial wall

Release of T-
Lymphocytes and
Monocytes

Smooth muscle
cell proliferate to
form a fibrous cap
Plaques protrude
to the vessels
which lead to
narrowing or
obstruction of
blood flow

Decrease Coronary
Tissue Perfusion

Collateral

circulation

Pallor
Myocardial
Ischemia Dyspnea

Faintness

Palpitation
Anaerobic
metabolism Dizziness

Production of lactic
acid (lactic
acidosis)

Prduction of
bradykinin which
leads to pain and
may radiate in the
different part of
the body

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