California State University, Dominguez Hills

Division of Health Sciences

Course: CLS 308 Pathophysiology for Health Sciences

Instructor: Dr. Paula J. D’Amore

Office Hours: Mon. 10am-1, W 12-1pm

Office Location: Welsh Hall WHA-330B

Telephone: 310-243-2212

Email: pdamore@csudh.edu

Catalog Description: This course is intended to provide the student with an understanding
of the various aspects of disease processes. Emphasis will be placed upon the etiology and
pathogenesis of a given disorder at the genetic, molecular, cellular and organ level.

Prerequisites: BID 250 and either BID 251 or CHE 112

Required Textbook: Pathology for the Health-Related Professions- (5th edit)

I. Damjanov, 2017
Varied Prices: can be purchased at university bookstore
Course Objectives and Student Learning Outcomes

1. To introduce the general concepts of disease processes and provide a

background for understanding specific disease mechanisms.

2. Basic mechanisms that lead to alterations of structure and function will be

covered.

3. Examine various pathologic alterations of different organ systems. The

etiology, pathology and physiology of a given disorder relating to a particular
organ system will be discussed.

4. Introduce students to the clinical aspects of pathology including laboratory tests

used for the diagnosis of diseases. Studies performed on patient’s samples
(blood, tissue, body fluids) to assess the pathophysiological changes will be
introduced.

5. A focused illustrative program with photographs, drawings and charts

throughout the book and various websites will be utilized to clarify the more
difficult concepts and demonstrate normal and disease processes.

B. STUDENT LEARNING OUTCOMES

Upon completion of the course, the student will be able to:

1. Describe the major aspects of pathologic disease processes of the organs

(discussed in this course) including:
a. etiology of the disease
b. pathogenic mechanisms of development- sequence of events leading to the
manifestations of the disease
c. structural alterations from the genetic, molecular, cellular and morphologic
levels.
d. changes affecting the organ function.

2. Describe the general pathologic mechanisms

a. Review the major changes that occur in inflammation
b. Describe the blood cells involved in inflammation.
c. Describe the soluble mediators that are involved in inflammation and what
is their function.
3. Compare the macroscopic and microscopic differences between normal and
neoplastic cells.
4. Identify the steps involved in carcinogenesis.

5. Demonstrate understanding of pathologic processes and physiological

alterations of the major organ systems.
Evaluation of Learning
Two midterms and a final examination will be given- each Midterm worth 33%,
Final Exam -34%
There will be no extra credit projects offered.

Grading: This course will be graded on a letter basis as follows:

93– 100 = A
90 – 92 = A-
87 – 89 = B+
83 – 86 = B
80 – 82 = B-
77 – 79 = C+
73 – 76 = C
70 – 72 = C-
67 - 69 = D+
60 - 68 = D
Less than 60= F

Class Attendance: All students are expected to attend every class meeting, fully
prepared and having read weekly assignments.

Tardiness: Students are expected to arrive for class on time.

Academic Integrity and Plagiarism

The University and the Division of Health Sciences have strict rules regarding
cheating and plagiarism. Any student who cheats on an examination will
automatically fail the course. Further action at the University level may also be
taken. Any student who plagiarizes any part or all of a paper will be given a fail
grade for the assignment and/or course. The subject of what constitutes plagiarism
will be discussed in class. For further information regarding cheating and
plagiarism, refer to the University Catalog.
Americans with Disabilities Act: CSUDH adheres to all applicable federal, state
and local laws, regulations, and guidelines with respect to providing reasonable
accomadiations for students with temporary and permanent disabilities. If you
have a disability that may adversely affect your work in this class, you are
encouraged to contact the University Disabled Students(DSS) Office for
information regarding special accommodations at www.csudh.edu/dss/main.html
or call 310-243- 3660. All disclosures of disabilities will be kept confidential.
DSS is located in WH B250.

COMPUTER SKILLS REQUIRED

Students will be required to use and access the following applications:
1. Blackboard, School Email, Power point presentations
2. Use search engines or online instructional resources
3. Word Processing

Electronic Devices

All Cell Phones must be placed on Vibrate and Text Messaging is not permitted
during lectures.
 SCHEDULE***
Depending on lecture each week, schedule can change
Week 1 Cell Pathology Chapter 1

Week 2 Inflammation Chapter 2

Week 4 Inflammation cont Chapter 2

Neoplasia Chapter 4
Week 5 Neoplasia Chapter 4

Fluids and Chapter 6

Hemodynamics
Week 6 Fluids and Chapter 6
Hemodynamics

Week 7 Mid Term Exam

Chapter 7 Cardiovascular Chapter 7

Week 8 Cardiovascular Chapter 7

Week 9 Respiratory System Chapter 8

Week 10 Respiratory Chapter 8

Week 11 GI System Chapter 10

Week 12 GI System Chapter 10

Week13 Mid term 2

Liver Chapt 11

Week 14 Liver. Gall Bladder Chapter 11

Week 15 Pancreas Chapter 12

Chapter

Week 16 Endocrinology(Partial) Chapter 17

Pituitary gland

Week 16 Final Exam

***Circumstances may require changes to the course and examination

schedule. Students are expected to make reasonable accomodations to any
such changes.