Вы находитесь на странице: 1из 2

Development and Validation of a Prediction Model for Prehospital Triage for Trauma Original Investigation Research

method for updating prediction models. Stat Med. systems. J Am Coll Surg. 2003;197(5):717-725. doi: Epidemiol. 2009;62(1):5-12. doi:10.1016/j.jclinepi.
2017;36(28):4529-4539. doi:10.1002/sim.7179 10.1016/S1072-7515(03)00749-X 2008.04.007
23. Janssen KJM, Moons KGM, Kalkman CJ, 32. Chang DC, Bass RR, Cornwell EE, Mackenzie EJ. 41. Barnes J, Hassan A, Cuerden R, Cookson R,
Grobbee DE, Vergouwe Y. Updating methods Undertriage of elderly trauma patients to Kohlhofer J. Comparison of injury severity between
improved the performance of a clinical prediction state-designated trauma centers. Arch Surg. 2008; AIS 2005 and AIS 1990 in a large injury database.
model in new patients. J Clin Epidemiol. 2008;61(1): 143(8):776-781. doi:10.1001/archsurg.143.8.776 Ann Adv Automot Med. 2009;53:83-89.
76-86. doi:10.1016/j.jclinepi.2007.04.018 33. Ichwan B, Darbha S, Shah MN, et al. 42. American College of Surgeons Committee on
24. R Development Core Team. R: a language and Geriatric-specific triage criteria are more sensitive Trauma. Resources for Optimal Care of the Injured
environment for statistical computing [serial than standard adult criteria in identifying need for Patient 2006. Chicago, IL: American College of
online]. Vienna, Austria: R Foundation for Statistical trauma center care in injured older adults. Ann Surgeons; 2006.
Computing; 2016. https://www.r-project.org/about. Emerg Med. 2015;65(1):92-100.e3. doi:10.1016/j. 43. Hedges JR, Feero S, Moore B, Haver DW, Shultz
html. Accessed October 31, 2018. annemergmed.2014.04.019 B. Comparison of prehospital trauma triage
25. van Laarhoven JJ, Lansink KW, van Heijl M, 34. Teasdale G, Maas A, Lecky F, Manley G, instruments in a semirural population. J Emerg Med.
Lichtveld RA, Leenen LP. Accuracy of the field triage Stocchetti N, Murray G. The Glasgow Coma Scale at 1987;5(3):197-208. doi:10.1016/0736-4679(87)
protocol in selecting severely injured patients after 40 years: standing the test of time. Lancet Neurol. 90179-X
high energy trauma. Injury. 2014;45(5):869-873. 2014;13(8):844-854. doi:10.1016/S1474-4422(14) 44. Newgard CD, Nelson MJ, Kampp M, et al.
doi:10.1016/j.injury.2013.12.010 70120-6 Out-of-hospital decision making and factors
26. Hamada SR, Gauss T, Duchateau FX, et al. 35. Wong TH, Krishnaswamy G, Nadkarni NV, et al. influencing the regional distribution of injured
Evaluation of the performance of French Combining the new injury severity score with an patients in a trauma system. J Trauma. 2011;70(6):
physician-staffed emergency medical service in the anatomical polytrauma injury variable predicts 1345-1353. doi:10.1097/TA.0b013e3182191a1b
triage of major trauma patients. J Trauma Acute mortality better than the new Injury Severity Score 45. Emerman CL, Shade B, Kubincanek J. A
Care Surg. 2014;76(6):1476-1483. doi:10.1097/TA. and the Injury Severity Score: a retrospective comparison of EMT judgment and prehospital
0000000000000239 cohort study. Scand J Trauma Resusc Emerg Med. trauma triage instruments. J Trauma. 1991;31(10):
27. Dinh MM, Bein KJ, Oliver M, Veillard AS, Ivers R. 2016;24:25. doi:10.1186/s13049-016-0215-6 1369-1375. doi:10.1097/00005373-199110000-
Refining the trauma triage algorithm at an 36. Lefering R, Huber-Wagner S, Nienaber U, 00009
Australian major trauma centre: derivation and Maegele M, Bouillon B. Update of the trauma risk 46. Fries GR, McCalla G, Levitt MA, Cordova R.
internal validation of a triage risk score. Eur J adjustment model of the TraumaRegister DGU™: A prospective comparison of paramedic judgment
Trauma Emerg Surg. 2014;40(1):67-74. doi:10.1007/ the Revised Injury Severity Classification, version II. and the trauma triage rule in the prehospital
s00068-013-0315-1 Crit Care. 2014;18(5):476. doi:10.1186/s13054-014- setting. Ann Emerg Med. 1994;24(5):885-889. doi:
28. Rubenson Wahlin R, Ponzer S, Skrifvars MB, 0476-2 10.1016/S0196-0644(94)70207-1
Lossius HM, Castrén M. Effect of an organizational 37. Scheetz LJ. Comparison of type and severity of 47. Newgard CD, Kampp M, Nelson M, et al;
change in a prehospital trauma care protocol and major injuries among undertriaged and correctly WESTRN Investigators. Deciphering the use and
trauma transport directive in a large urban city: triaged older patients. J Emerg Med. 2012;43(6): predictive value of “emergency medical services
a before and after study. Scand J Trauma Resusc 1020-1028. doi:10.1016/j.jemermed.2011.09.036 provider judgment” in out-of-hospital trauma
Emerg Med. 2016;24:26. doi:10.1186/s13049-016- 38. Schoell SL, Doud AN, Weaver AA, et al. triage: a multisite, mixed methods assessment.
0218-3 Development of a time sensitivity score for J Trauma Acute Care Surg. 2012;72(5):1239-1248.
29. Champion HR, Sacco WJ, Copes WS, Gann DS, frequently occurring motor vehicle crash injuries. doi:10.1097/TA.0b013e3182468b51
Gennarelli TA, Flanagan ME. A revision of the J Am Coll Surg. 2015;220(3):305-312.e3. doi:10. 48. Harmsen AM, Giannakopoulos GF, Moerbeek
Trauma Score. J Trauma. 1989;29(5):623-629. doi: 1016/j.jamcollsurg.2014.11.022 PR, Jansma EP, Bonjer HJ, Bloemers FW. The
10.1097/00005373-198905000-00017 39. Cole TB. Global road safety crisis remedy influence of prehospital time on trauma patients
30. Ocak G, Sturms LM, Hoogeveen JM, Le Cessie sought: 1.2 million killed, 50 million injured annually. outcome: a systematic review. Injury. 2015;46(4):
S, Jukema GN. Prehospital identification of major JAMA. 2004;291(21):2531-2532. doi:10.1001/jama. 602-609. doi:10.1016/j.injury.2015.01.008
trauma patients. Langenbecks Arch Surg. 2009;394 291.21.2531
(2):285-292. doi:10.1007/s00423-008-0340-4 40. Leeflang MM, Bossuyt PM, Irwig L. Diagnostic
31. Vassar MJ, Holcroft JJ, Knudson MM, Kizer KW. test accuracy may vary with prevalence:
Fractures in access to and assessment of trauma implications for evidence-based diagnosis. J Clin

Invited Commentary

Optimizing Prehospital Trauma Triage—A Step Closer?


Jason S. Haukoos, MD, MSc; Eric M. Campion, MD; Peter T. Pons, MD

Identifying patients with severe injuries in the prehospital In this issue of JAMA Surgery, van Rein and colleagues5
setting remains the first step in a series of interventions that report the results of a large-scale observational study with
aim to reduce trauma-related morbidity and mortality. In the goal of developing an instrument to improve field
2011, the Centers for Disease Control and Prevention and the trauma triage. The authors evaluated 43 candidate variables
American College of Sur- using severe injury (ie, an injury severity score of more than
Related article page 421
geons Committee on Trauma 15) as the outcome. The final model included age, systolic
partnered to revise and up- blood pressure, Glasgow Coma Scale score, injury mecha-
date the Field Triage Decision Scheme (FTDS) with the goal of nism, and injury characteristics (ie, a penetrating injury to
providing a structure to decision making by paramedics when the head or torso, signs or symptoms of the head or neck, or
determining appropriate destinations for patients with expected injury to the thorax or to ≥2 body regions) with a
injuries.1 Recent research suggests that the sensitivity of the reported sensitivity of 88.8% and specificity of 50% from
FTDS is lower than previously described, particularly for vul- the derivation cohort. A comparable calibration and dis-
nerable populations (eg, elderly people), and lower than the crimination of the model was reported for a separate exter-
target of 95% (ie, 5% undertriage rate).2-4 nal cohort.

jamasurgery.com (Reprinted) JAMA Surgery May 2019 Volume 154, Number 5 429

© 2019 American Medical Association. All rights reserved.

Downloaded From: https://jamanetwork.com/ by a Universidad Del Rosario User on 10/30/2019


Research Original Investigation Development and Validation of a Prediction Model for Prehospital Triage for Trauma

While laudable, developing a highly sensitive tool with- Using prehospital data also provides a unique challenge in
out sacrificing specificity is challenging, and this study that they are collected during a short window when caring for
must be assessed in the context of several limitations. While patients with acute injuries or illness and it often results in large
the authors report a comparable model performance numbers of missingness, as seen in this study. While the au-
between the derivation and validation portions of this thors used quality missing data methods (ie, multiple imputa-
study, the sensitivity of the tool remains unclear when tion), they assumed the data were missing at random, which is
applied to an external cohort. Moreover, while the reported an important assumption of this approach. Unfortunately, this
sensitivity improved the baseline rate of undertriage assumption is often violated, especially when data are col-
(78.4%) using a triage scheme specific to the Netherlands, it lected from patients with acute injuries. Although using mul-
is only marginally improved compared with a recent tiple imputation in this context is reasonable, the results must
population-based evaluation of the FTDS and still falls short be interpreted with caution.
of the targeted 95% threshold.2 In summary, it remains unclear how well this tool will
Using injury severity as an outcome is common but its sole perform when applied prospectively as a part of routine care.
use constrains the interpretation of results. Approaches to This new tool, while possibly a step closer, must be inte-
trauma triage should also be assessed by using the need for grated into prehospital care and rigorously evaluated among
emergent intervention and critical resource use.6,7 Further, the a broader, unselected trauma population (including children)
investigators appeared to use an adult population for whom and shown to be at least equivalent when directly compared
emergent return to the hospital occurred, which may have with current standards, including the FTDS. Ultimately,
excluded patients with more occult injuries; among those in- large-scale, pragmatic comparative effectiveness and imple-
cluded in the validation cohort, only 165 (2.4%) had an injury mentation research is needed to understand how best to
severity score of more than 15, which appears lower than the accurately identify patients who require specialized trauma
percentage reported from other population-based trauma tri- care and we may have reached the limits of field triage using
age studies.2 Unfortunately, this potential for selection may common prehospital data inputs. Novel physiologic mea-
have artificially increased the tool’s specificity by excluding surement or diagnostic technologies may now be required to
patients who did not meet the triage criteria. further improve field triage accuracy.

ARTICLE INFORMATION R01DA042982 from the National Institutes of 4. Newgard CD, Richardson D, Holmes JF, et al;
Author Affiliations: Department of Emergency Health. No other disclosures are reported. Western Emergency Services Translational
Medicine, Denver Health Medical Center, Denver, Research Network (WESTRN) Investigators.
Colorado (Haukoos, Pons); Division of Paramedic, REFERENCES Physiologic field triage criteria for identifying
Denver Health Medical Center, Denver, Colorado 1. Sasser SM, Hunt RC, Faul M, et al; Centers for seriously injured older adults. Prehosp Emerg Care.
(Haukoos, Pons); Department of Emergency Disease Control and Prevention (CDC). Guidelines 2014;18(4):461-470. doi:10.3109/10903127.2014.
Medicine, University of Colorado School of for field triage of injured patients: 912707
Medicine, Aurora (Haukoos, Pons); Department of recommendations of the National Expert Panel on 5. van Rein EAJ, van der Shuijs R, Voskens FJ, et al.
Epidemiology, Colorado School of Public Health, Field Triage, 2011. MMWR Recomm Rep. 2012;61(RR- Development and validation of a prediction model
Aurora (Haukoos); Department of Surgery, Denver 1):1-20. for prehospital triage of trauma patients [published
Health Medical Center, Denver, Colorado 2. Newgard CD, Zive D, Holmes JF, et al; WESTRN online February 6, 2019]. JAMA Surg. doi:10.1001/
(Campion); Department of Surgery, University of investigators. A multisite assessment of the jamasurg.2018.4752
Colorado School of Medicine, Aurora (Campion). American College of Surgeons Committee on 6. Boatright DH, Byyny RL, Hopkins E, et al.
Trauma field triage decision scheme for identifying Validation of rules to predict emergent surgical
Corresponding Author: Jason S. Haukoos, MD,
seriously injured children and adults. J Am Coll Surg. intervention in pediatric trauma patients. J Am Coll
MSc, Department of Emergency Medicine, Denver
2011;213(6):709-721. doi:10.1016/j.jamcollsurg.2011. Surg. 2013;216(6):1094-1102, 1102.e1-1102.e6. doi:
Health Medical Center, 777 Bannock St, Mail Code
09.012 10.1016/j.jamcollsurg.2013.02.013
0108, Denver, CO 80204 (jason.haukoos@dhha.
org). 3. Newgard CD, Fu R, Zive D, et al. Prospective 7. Haukoos JS, Byyny RL, Erickson C, et al.
validation of the National Field Triage Guidelines for Validation and refinement of a rule to predict
Published Online: February 6, 2019. Identifying Seriously Injured Persons. J Am Coll Surg. emergency intervention in adult trauma patients.
doi:10.1001/jamasurg.2018.4764 2016;222(2):146-58.e2. doi:10.1016/j.jamcollsurg. Ann Emerg Med. 2011;58(2):164-171. doi:10.1016/j.
Conflict of Interest Disclosures: Dr Haukoos is 2015.10.016 annemergmed.2011.02.027
funded in part by grants R01AI106057 and

430 JAMA Surgery May 2019 Volume 154, Number 5 (Reprinted) jamasurgery.com

© 2019 American Medical Association. All rights reserved.

Downloaded From: https://jamanetwork.com/ by a Universidad Del Rosario User on 10/30/2019

Вам также может понравиться