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Mastitis is an inflammation of breast tissue that sometimes involves an

infection. The inflammation results in breast pain, swelling, warmth and


redness. You might also have fever and chills. Mastitis most commonly affects
women who are breast-feeding (lactation mastitis)

Duct ectasia of the breast, mammary duct ectasia or plasma cell mastitis is a
condition in which occurs when a milk duct ‫ تحت‬beneath the nipple widens,
the duct walls thicken and the duct fills with fluid. This is the most common
cause of greenish discharge.

Granulomatous mastitis (GM) is a rare chronic inflammatory breast condition


Granulomatous changes occur around lobules and ducts of the breast in the
absence of specific infection, trauma.

Infection refers to the invasion and multiplication of a pathogen within the


body, while inflammation is the body's protective response against infection.
Inflammation is a complex process involving various types of immune cells,

Fibroadenomas of the Breast. Fibroadenomas are common benign (non-


cancerous) breast tumors made up of both glandular tissue and stromal
(connective) tissue. Fibroadenomas are most common in women in their 20s
and 30s, but they can be found in women of any age. They tend to shrink
after a woman goes through menopause

Glandular tissue is the part of the breast that makes milk, called the lobes,
and the tubes that carry milk to the nipple, called ducts. Together, fibrous
and glandular tissue are called fibroglandular tissue. Fatty tissue fills the
space between the fibrous tissue, lobes, and ducts.

Phyllodes Tumors. Most Phyllodes tumors are benign, but 10 percent are
malignant. Cancerous Phyllodes tumors are an unusual presentation of
breast cancer. they grow in the connective tissue of the breast, not in the
ducts.)

Large duct papilloma : are single tumors that often grow in the large milk
ducts near the nipple. They are a common cause of clear or bloody nipple
discharge, especially when it comes from only one breast. They may be felt
as a small lump behind or next to the nipple.

Atypia : a condition of being irregular or nonstandard) is a histopathologic


term for a structural abnormality in a cell, i.e. it is used to describe atypical
cells. Atypia can be caused by an infection or irritation if diagnosed in a Pap
smear, for example

A sarcoma is a cancer that arises from transformed cells of mesenchymal


(connective tissue) origin. Connective tissue is a broad term that includes
bone, cartilage, fat, vascular, or hematopoietic tissues, and sarcomas can
arise in any of these types of tissues

When genome-wide expression profiles of tumors are compared to those of


normal tissues, the most recurring transcriptional pattern is characterized
by an increased expression of cell-cycle and proliferation-associated genes,
collectively referred to as the 'proliferation cluster'.

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