No catara symptom; prioritize the fever- give paracetimol as
VIROLOGY
Syphilis- can cross the placenta  and cause anomalies; can be
treated before 18 months of gestation
Primary- chunker painless ulcer with rubbery edge
Part of the cell that is affected: nucleus-> viral DNA
RNA viruses single stran; DNA- double strand
RNA viruses
1.       RNA sense- served as mRNA
2.        RNA antisense
3.       Capsid
Envelope- must be destroyed by meds
The virus cannot be fully eradicated; the immune system must
always be up else the virus will resurface
Herpersviruses I: Cytomegalovirus
Close contact- through direct contact; mother must wear mask
to prevent her child from contracting the disease
May cause genetical anomaly to the fetus
Immuno-compromised patients and infants are more
susceptible
These antiviral drugs are more toxic to infants so diagnose
carefully
Herpesviruses I: Epstein-Barr virus
Nasophrayngeal carcinoma caused by cigarette smoking is
more usual here in the Philippines through tissue biopsy (Do
not touch because it has affected the squamous cells)
Versus Burkitt’s lymphoma
Jackie O had lymphoma of the nodes
Herpesviruses I: HHV-6 & 7
6: Subtypes: A & B
Roseola infantum
Face and trunk fine rashes
No peeling off versus  DNA viruses: Papillomavirus
antipyretic
Turn patient to the side, side rails of bed up when seizure
ensures
7: ask in which body part the rashes started
HHV 8
May tubig yung rashes 
Usually present in people with full-blown AIDS
Herpesviruses II: herpes simplex
Similar to bulutong tubig
HSV-1 (common in children): very red eyes
(keratoconjunctivitis-> may lead to blindness)
HSV-2: May cause genital ulceration (increases the risk of HIV
transmission)
 
Varicella Zoster virus
Transmission is through direct contact duh
Superficial scars which may take years to fade
DNA viruses: Adenovirus
DNA viruses: Parvovirus
May cause erythema infectiosum or fifth disease (Not
contagious)
Usually occurs in the colder months
There is malar blush or slap cheeks; no discomfort
Next: Trunk and extremities
On the 5th day: Reticular or lacy-pattern rash with central
clearing
Fever is also low so need to worry
No vaccine present
Different from parvovirus in dogs
Responsible for genital warts Symptomatic treatment: analgesic, anti pyretic, alternating cold
Cryosurgery to remove the warts (repeated) and hot compress, soft diet, complete bedrest
Cannot fully eradicate it In males: wear properly fitted suspensory- supporter; not
Puts females at risk for HPV cancer so there is a vaccine advised to walk around- may increase inflammation

DNA viruses: Poxvirus Rubivirus/German measles

Causes smallpox, monkeypox (zoonotic- infects patches of Through direct contact: aerial droplets, through linens and
skin only), orf (may cause pustular dermatitis- comes from articles infected by droplets and urine
goats) Low grade fever, mild cataral symptoms
Moluscum contagiosum: Pearl-like skin lesions Can cause (?) Rothel disease
Tanapox: Single nodular skin lesion (may be contracted from Incubation period: 10-21 days
furry animals) Transplacental and may reach the infant and cause anomalies
Face, chest and will spread to extremities
RNA Viruses Rashes for three days, no discoloratiom after
1. Morbilivirus:  Pinkish not reddish
1. affects the epithelial cells, results in viraemia; Kulani sa likod ng tenga (suboccipital area)
contagious through droplets; coplic spots in the Forschermer spots (soft lesions in the soft palate) also seen in
cheek opposite the second molar (use a tongue strep fever
depressor), hairline Complication: otitis media, encephalitis
2. Leaves discoloration after seven days (do not Mother in the first/second/third trimester- may also lead to
peel off) premature labor, abortion, congenital anomalies
3. Fever peaks at the height of the rashes First trimester: teratogenic
4. Remitent IgM, IgG antibodies/NAAT
5. Morbilivirus: may lead to pneumonia (cause of
death in children) Influenza
6. Dx through EIA Antigenic shift versus drift
7. Give mucolitoc expectorants and pausok Myalgia, cough
b. Mumps virusMumps virus: aerial route/ droplets  Avian flu: complication-> pneumonia
May cause sterility (if two balls/ovaries are affected) NAAT, direct immunofluorescent
Parotid gland enlargement and tenderness Case hx: intake of chicken?
Pain when chewing (odynophagia) Vaccination: 70% of protection
May cause neurologic complications: meningitis, encephalitis, No vaccine for avian flu yet
permanent deafness, olineorhitis?, optic neuritis
Orchitis: Unilateral testes affectation but may also be bilateral Parainfluenza
after five to ten days of illness (after mawala ang enlargement) Treatment: medication and humidification (humidified oxygen)
Myocarditis
RS virus Also if it continues for more than 24hrs
Coryza in newborns- difficulty in breathing Tx: nuprintrivir
Symptomatic treatment
Stiminilation (?) Rotavirus
X vaccine Main cause of viral diarrhea
No specific antibiotic; replenish lost fluids
Coronavirus and electrolytes
Causes coryza-like sickness similar to rhinovirus
SARS: Through droplets Norovirus and Astrovirus
Must have continuous fever Noro: fecal-oral/aerosol
Mild respiratory symptoms at the onset I.e. Yemen- contaminated water by Kingdom of Saudi Arabia
But may lead to dry, unproductive cough Astro: mqy cause accute diarrhea
Hypoxemia Important to request for stool exam (3x)
High risk: housemates *wards are ordered to be closed
Antiviral drug: remdicivir, ribavirin in combo with steroid (to
reduce inflammation) Hepatitis A
20 strains of COVID Affects the liver lobules/hepatocytes/kaufer? cells
Changes liver cells structure and fxn: swelling and
Enterovirus degeneration-> repair
Heinmeilen (?) disease High mortality
Polymelitis virus Chief cause of hepatic cancer and cirrhosis
1 Brunhilde Accure stage-very contagious
2 lansing Three doses of vaccine
3?
Treatment: artificial ventilation Hepatitis B
Vaccine: parenteral; oral luve attenuated sabin; oral polio One dose of vaccine
vaccine 2-3 drops orally  Hepa B immunoglubbulin
Under the tongue? Hippie hepatitis-common in drug users
X eating after the child has been given the vaccine to maintain Pegylated alpha-interferon
the right dissolutiob for best absorption Sex partners are particularly susceptible

Rhinovirus Hepatitis C
Common cold
Infects the mucosa and submucosa of the URT Rabies
see if nasal discharge changes its color the you may give an Infects warm blooded animals
antibiotic Found in the saliva
*negribodies Grade 2 
Incubation: average 20-60 Grade 3 circulatory failure, rapid and weak pulse
Variable incubation period d/t viral dose, location of bite, host Grade 4: shock, palpatory blood pressure
response (low immune-faster time, area where you got beaten, DEATH
animal who bit you (10-14 days) Tx: symptomatic and supportive treatment; side drip; vit c for
Tx: copious washing with soap and water capillary permeability (skin test!!!); IV fluid; antipyretic
Stage 2: increased excitement Xaspirin!!!! (Will lead to bleeding)
Prodromal (?) 3. Japanese B encephalitis
Terminal: tachycardia, prog paralysis 3. Lassa Fever
Cause of death: resp failure 3. Ebola and Marburg virus
No cure for rabies 3. Hantavirus
Clinical and epidemiological features 3. Nipah and Hendra virus
Bring the dog’s head sa clinic kung papatayin mo man
Two booster doses if bitten again after 3-6 mos of the first bite
Six months after: seven daily injection and antiserum
Coprosky (?) high cure rate
Semple vaccine- cheaper, more widely used
Decapitation of the dog, then send dog to the clinic

Yellow fever virus

May not be present here in Ph
X hanging underwear and pants
Attenuated vaccine

Dengue
July-October
Capillaries- Herman’s sign
The virus will destroy the new platelets thus it will lower in
number
Decrease blood coagulation factor 7, 5 and 9
Classification of dengue according to severity
Grade 1: torniquet test (10-15 secs) then marks will be seen
Rample test (Bp apparatus: bp up) 110/70 add 110+70/90 (bp:
90, stop for several seconds- marks will be seen); platelet
count has decreased; do not wait for patient to bleed because
it will not clot; PTK, severe nosebleeding