Rohanisah B.

Guro
Medicine I

Food Ingestion

Broken down into glucose

Glucose is absorbed in the small

intestine into the bloodstream

Increase of Blood Glucose Levels

Pancrease is stimulated to release the

hormone Insulin into the bloodstream Insulinoma

Insulin Target Fat Cells which has

Insulin Receptors on its surface
Glucose increased Insulin increased C-peptide increased

Insulin binds to these receptors

Secretions Signs and Symptoms

Triggers a sequence of events to occur
inside the cell

- Insulin
- Gastrin
Hypoglycemia Severe Symptoms
- 5-hydroxyindolic acid
Uptake of glucose - adrenocorticotropic
hormone
- Glucagon - confusion - convulsions
Promoting Glycogen - Somastrin - low blood sugar - rapid heart
glucose storage in - blurring of vision attack
the Lipids - unconsciousness - coma

Inhibits the
breakdown of
Lipids

Stimulates
protein synthesis

FIGURE. Pathophysiology of Insulinoma