Faculty of Medicine

Department of Microbiology & Immunology

General Microbiology for Dental Students
(0604311)
Second Hour Exam
First semester 2016/2017
22/11/2016 (11:00-12:00)
Instructors : Dr. Murad Ibrahim

Student Name: _____________________Student No.: ____

Section: 30

Exam Duration: 60 Minutes

75 Points

1
 ANSWER SHEET
Student Name: Student Number:
Q1 Q8 Q15
Q2 Q9 Q16
Q3 Q10 Q17
Q4 Q11 Q18
Q5 Q12 Q19
Q6 Q13 Q20
Q7 Q14

Part Two: True/False

A B C D E
Q1
Q2
Q3
Q4
Q5
Q6
Q7

Good Luck

2
 Part One: Choose one answer only (40 Points)
1. The soil is natural habitat for certain microorganisms of medical importance.
Which one of the following is likely to reside there?
A. Staphylococcus aureus
B. Streptococcus pyogenes
C. Clostridium tetani
D. E. coli
2. All of the following diseases can be transmitted from mother to fetus through
placenta EXCEPT
A. Syphilis
B. Pneumonia
C. Rubella
D. Toxoplasmosis
3. Staphylococcus Epidermidis can produce in IV drug-abusers because it is
normal flora of .
A. Cystitis/Male urinary tract
B. Infective Endocarditis/Skin
C. Colon cancer/Digestive system
D. Pneumonia/Respiratory tract
4. All of the following are respiratory tract infection EXCEPT
A. Tuberculosis
B. Meningitis
C. Common cold
D. Pneumonia
5. Which is True concerning incubation period
A. Patient cannot transmit the disease during incubation period
B. There is destruction of human tissues in the site of infection during incubation period
C. The length of incubation period is the same for all organisms
D. Patient has signs and symptoms of disease
6. All of the following bacteria can lead to pyogenic infection EXCEPT
A. Staphylococcus pyogens
B. Mycobacterium tuberculosis
C. Streptococcus pneumonia
D. Haemophillus Influenzae
7. The causative agent for peptic ulcer is
A. Haemophilus influenza
B. Streptococcus pneumoniae
C. Neisseria meningitides
D. Helicobacter pylori

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8. All of the following are virulence factors for staphylococcus aureus EXCEPT
A. Collagenase
B. Protein A
C. Exotoxin production
D. Protein M
9. Which of the following transport bacterial DNA to other bacteria via
bacteriophages:
A. Conjugation
B. Transfection
C. Transformation
D. Transduction
10. It is part of gram negative cell wall
A. Endotoxin
B. Exotoxin
C. Both A and B
D. Neither A nor B
11. Used for vaccination against Tetanus
A. Endotoxin
B. Exotoxin
C. Both A and B
D. Neither A nor B
12. Mycobacteria tuberculosis and human lung tissues
A. Opportinistic pathogen
B. Obligatory external pathogen
C. Obligatory internal pathogen
D. Non pathogen
13. The role of the normal flora include all the following EXCEPT
A. Colonization resistance
B. Improvement of absorption of the GI mucosa
C. Produce vitamin K
D. Establishment of GI cancer
14. Scientists have discovered how to put together a bacteriophage with the protein
coat of phage T2 and the DNA of phage T4. If this composite phage were allowed
to infect a bacterium, the phages produced in the host cell would have
A. The protein of T4 and the DNA of T2
B. The protein and DNA of T2.
C. The protein of T2 and the DNA of T4
D. The protein and DNA of T4

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15. The process by which a nonpathogenic streptococcus pneumonia is changed into
a pathogenic encapsulated cell is called:
A. Conjugation
B. Transformation
C. Lysogenic conversion
D. Transduction
16. The correct order regarding the infectious dose (from low to high) is
A. Shigella species, Salmonella species, Mycobacterium tuberculosis
B. Shigella species, Mycobacterium tuberculosis, Salmonella species
C. Mycobacterium tuberculosis, Shigella species, Salmonella species
D. All species have same ID
17. All of the following are stable organisms EXCEPT
A. Mycobacterium tuberculosis
B. Clostridium tetani
C. Neisseria gonorrhoeae
D. Staphylococcus aureus
18. All of the following can be transmitted to a newborn by vaginal delivery EXCEPT
A. Group A streptococci
B. Neisseria gonorrhoeae
C. Candida albicans
D. Group B streptococci
19. All of the following can be vertically transmitted from mother to fetus EXCEPT
A. Hepatitis A
B. Human immunodeficiency virus
C. Toxoplasmosis
D. Rubella virus (German Measles)
20. Which one of the following bacteria is found in the greatest numbers in the colon?
A. Clostridium difficile
B. Bacteroides fragilis
C. Escherichia coli
D. Pseudomonas aeruginosa

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Part Two: True or False (35 Points)
1- Zoonotic infections include
A. Brucellosis
B. Toxoplasmosis
C. Oral thrush
D. Rabies
E. Leishmaniasis

2- Advantages of probiotics include

A. Have the potential to prevent colon cancer
B. Improving immune function and preventing infections
C. They can help regulate your digestive system by managing lactose intolerance
D. Have the potential to eradicate external pathogens
E. Worsens systems of irritable bowel syndrome and colitis

3- Obligatory intracellular parasites

A. Mycobacterium
B. Chlamydia
C. Legionella
D. Streptococcus pneumonia
E. Brucella

4- Pathogenescity islands (PI)

A. Genes that encode many virulence factors on bacterial chromosome
B. Nonpathogenic variants have PI on their genomes
C. Genes that encode many virulence factors on bacterial plasmids
D. Are found in E.coli
E. Secreted polypeptide from gram positive bacteria

5- Can be transmitted vertically

A. Clostridium tetani
B. Shigella dysenteriae
C. Streptococcus pneumonia
D. Chlamydia trachomatis
E. E. coli

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6- Transfer of DNA between bacterial cells
A. Conjugation is the mating of two bacterial cells
B. Transduction is the transfer of cell DNA by means of a bacterial virus
C. Integration of F plasmid with bacterial chromosome leads to F+ bacteria
D. Conjugation need physical contact
E. Transformation needs competent bacterial cell

7- Condition/s that create/s opportunities for normal flora to produce disease include
A. 56 year-old male
B. Antibiotic Administration
C. Introduction of a member of normal flora into unusual site
D. 20 year-old female
E. Dental extraction

Good Luck