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SYSTEMATIC REVIEW

Efficacy of conventional cord versus cordless techniques for


gingival displacement: A systematic review and meta-analysis
Felipe V. Martins, DDS, MS,a Ronaldo B. Santana, DDS, MS, PhD,b and Edgard M. Fonseca, DDS, MS, PhDc

Ceramic restorations with ABSTRACT


resin cement have been
Statement of problem. Unsatisfactory adaptation of restorations with subgingival margins can
increasingly used because of cause problems such as accumulation of biofilm, secondary caries, and inflammation of the
the demand for esthetic treat- periodontal tissue. Therefore, special attention should be given to gingival displacement and
ments.1-6 However, an unsat- impression procedures to optimize marginal fit.
isfactory adaptation of the
Purpose. The purpose of this systematic review and meta-analysis was to compare gingival
restorations with subgingival displacement with conventional cords and cordless techniques and determine the reliability of
margins can cause problems the measurement methodologies.
including accumulation of
Material and methods. This study followed the Preferred Reporting Items for Systematic Reviews
biofilm, secondary caries, and
and Meta-Analyses (PRISMA) statement and identified studies through September 2018. The studies
inflammation of the peri- were submitted to the Cochrane risk-of-bias assessment. The gingival displacement was evaluated
odontal tissue.7-13 Therefore, by using the Review Manager Software.
special attention should be
Results. Nine studies were selected, and the most common risks of bias were random sequence
given to the gingival displace- generation, blinding of outcome assessment, and absence of sample size calculation. Most of the
ment and impression proced- studies reported obtaining a width greater than 0.2 mm.
ures to optimize the marginal
Conclusions. The cord technique resulted in increased displacement when compared with the
fit of the restorations.
cordless technique. The evaluation of sulcular width with digital microscope images obtained
The mechanical insertion of from sectioned gypsum casts is an adequate and versatile experimental methodology for
cords into the sulcus has been measuring displacement. (J Prosthet Dent 2019;-:---)
a traditional technique for
gingival displacement (GD).14-18 However, this technique sulcus,14,16 eliminating the need to physically compress the
is not able to control crevicular fluid seepage,12,15-17 material into the sulcus and minimizing injury.15-18,36-38
leading to the chemomechanical method using cords Expansion of the materials mechanically displaces
impregnated with hemostatic agents, vasoconstrictors, or the gingiva, and the materials absorb crevicular
astringents.11,12,19-27 During the insertion of the cords, fluid.11,12,19-22,24-26
pressure may damage the epithelial attachment28-33 or Clinical trials have compared the gingival displace-
cause discomfort, gingival bleeding, direct trauma to the ment produced by the cord and cordless tech-
sulcular epithelium, or gingival recession.15,30-32 niques.11,12,19-22,24-26 Unfortunately, no definitive clinical
Cordless techniques were introduced to increase pa- recommendations have been made with regard to the
tient comfort and simplify the gingival displacement adequacy of specific materials and techniques of gingival
process.14-18,33-35 Cordless displacement systems are displacement, possibly because of the variability of ma-
available as a paste or foam that is injected into the terials tested and the way the sulcular width was

a
Postgraduate student, Federal Fluminense University (UFF), Niteroi, Rio de Janeiro, Brazil.
b
Professor, Department of Periodontology, Federal Fluminense University (UFF), Niteroi, Rio de Janeiro, Brazil.
c
Professor, Department of Dental Technique, Federal Fluminense University (UFF), Niteroi, Rio de Janeiro, Brazil.

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Table 1. MEDLINE/PubMed Medical Subject Heading (MeSH) and


Clinical Implications keywords (free term)
Database Search Methodology
Impression procedures for fixed dental prostheses PubMed ((((((((((((((((((((((human[MeSH Terms]) OR Gingival tissues[MeSH
with a subgingival finish line require gingival Terms]) OR intracrevicular margin[MeSH Terms]) OR Periodontal Index
[MeSH Terms]) OR human[Title/Abstract]) OR Gingival tissues[Title/
displacement. Cord and cordless techniques may Abstract]) OR intracrevicular margin[Title/Abstract]) OR Periodontal
present equivalent clinical performance in selective Index[Title/Abstract]) OR teeth[Title/Abstract]) OR tooth[Title/
Abstract]) OR incisor[Title/Abstract]) OR canine[Title/Abstract]) OR
clinical scenarios such as abutments located in the premolar[Title/Abstract]) OR molar[Title/Abstract]) OR man[Title/
anterior maxilla and shallow finish lines. The present Abstract]) OR woman[Title/Abstract]) OR masculine[Title/Abstract]) OR
male[Title/Abstract]) OR famale[Title/Abstract])) AND
results may provide a basis for the adequate ((((((((((((astringent retraction paste) OR Gingival Retraction Paste) OR
selection of displacement techniques. Retraction Paste) OR Chemico-mechanical[MeSH Terms]) OR
astringent retraction paste) OR Gingival Retraction Paste) OR
Retraction Paste) OR Gingival Paste) OR cordless) OR Chemico-
mechanical) OR Chemico mechanical) OR Chemico)) AND
((((((Retraction cords[MeSH Terms]) OR Retraction cords[Title/
measured. The purpose of this systematic review and Abstract]) OR Retraction cord[Title/Abstract]) OR cords[Title/Abstract])
meta-analysis was to answer the following research OR cord[Title/Abstract]) OR mechanical[Title/Abstract])) AND
(((((((((((((sulcular width[MeSH Terms]) OR gingival displacement
question: In gingival displacement, what are the differ- [MeSH Terms]) OR Sulcular expansion[MeSH Terms]) OR sulcular
ences resulting from the use of conventional cord tech- width[Title/Abstract]) OR width[Title/Abstract]) OR gingival
displacement[Title/Abstract]) OR displacement[Title/Abstract]) OR
niques and cordless techniques, and how reliable are the Sulcular expansion[Title/Abstract]) OR expansion[Title/Abstract]) OR
measurement methodologies? mm[Title/Abstract]) OR millimeter[Title/Abstract]) OR microns[Title/
Abstract]) OR mm[Title/Abstract])

MATERIAL AND METHODS


This study followed the Preferred Reporting Items for
allocation concealment, blinding of participants and
Systematic Review and Meta-Analyses (PRISMA)
personnel, blinding of outcome assessment, incomplete
guidelines. The review was registered in the International
outcome data, and other sources of bias. Each parameter
Prospective Register of Systematic Reviews (PROSPERO)
was classified as “Yes” for low risk of bias, “No” for high
CRD42019118466. The population, intervention, control,
risk of bias, or “Unclear” when the information could not
and outcome (PICO) tool was used. The population (P)
be found. The reviewers performed the analysis inde-
comprised vital and nonvital incisors, canines, premolars,
pendently, and the final decision was taken with the
and molars of adult humans. The intervention (I) was the
consensus of the authors (F.V.M., R.B.S.).
GD performed with the cordless technique. The control
For each included study, the following data were
group (C) was the GD performed with the mechanical or
collected: dental elements, with or without tooth prepa-
mechanochemical technique with displacement cords.
ration, cord and cordless manufacturer, cord thickness,
The outcome of interest (O) was the measurement of the
astringent used, impression and gypsum material, and
sulcular width. Only in vivo study designs (S) were
the method of evaluation of the sulcular width.
selected.
In the meta-analysis, the mean and standard devia-
The MEDLINE/PubMed, Web of Science Core
tion of the GD were analyzed by using a software pro-
Collection, and Scopus databases were searched to
gram (Review Manager, version 5.3; The Cochrane
identify studies up to September 2018, with no limit on
Collaboration). For studies with multiple data, the Rev-
publication year. For MEDLINE/PubMed, Medical Sub-
Man calculator was used to make possible a simple pair
ject Heading (MeSH) and keywords (free term) were
analysis. A value of P!.05 was considered statistically
used (Table 1).
significant. The I2 inconsistency test was used to assess
Titles and abstracts were evaluated independently by
heterogeneity.5 When high heterogeneity was detected,
the authors (F.V.M., R.B.S.) and selected according to the
the “one study remove test” was performed to detect
following criteria: GD performed with the cordless
which study may have influenced the heterogeneity.5
technique on adult humans. Then, the full text was
evaluated and included according to the following
RESULTS
criteria: GD performed with the cord technique and the
measurement, in millimeters or micrometers, of GD Figure 1 summarizes the selection process. Nine studies
evaluated with a microscope. Studies that did not report were included as listed in Table 2. The risk of bias is
the absence of gingival inflammation, bleeding on shown in Figures 2, 3. The most common risks of bias
probing, plaque index zero, and malocclusion were were the absence of sample size calculation, random
excluded. The final inclusion was done with the sequence generation, and blinding of outcome assess-
consensus of the authors (F.V.M., R.B.S.). ment. Most of the studies did not perform a random
The Cochrane risk-of-bias tool was used according to sequence because each volunteer was subjected to
the following parameters: random sequence generation, all GD techniques. The information about allocation

THE JOURNAL OF PROSTHETIC DENTISTRY Martins et al


- 2019 3

PubMed Web of Science Scopus


19 studies 20 studies 31 studies

70 studies

34 duplicate papers removed

36 studies

Step 1: Titles and abastracts reviewed by


21 papers excluded
two authors

15 studies

Step 2: Articles reviewed and selected by


6 papers excluded
the authors’ consensus

9 studies

Figure 1. Study selection.

Table 2. Studies included


Astringent
Tooth Cord Cord Used With Cordless Impression Gypsum Image
Author Tooth Preparation Manufacturer Thickness Cord Material Material Material Microscope Software
Tiwari 11 N/A N/A N/A Aluminum -Magic Foam Addition Type IV die Stereomicroscope Did not use
et al,19 2018 chloride Cord, Coltene silicone stone, Kalabhai (manufacturer not
(manufacturer -Racegel, (manufacturer informed)
not informed) Septodont not informed)
Shrivastava 11 and 21 Yes Roeko Stay- #0 15% Aluminum -Magic Foam Addition Type IV die Optical Image Pro
et al,20 2015 put, Coltene chloride Cord, Coltene silicone, Aquasil stone Elite microscope, Plus 3.0
(indigenously -Expasyl paste, Ultra XLV, Rock, Olympus
made) Satelec Dentsply Sirona Zhermack
Raghav 16 Yes Ultrapak, N/A 25% Aluminum -Magic Foam Addition Type IV die Optical -Axiovision,
et al,21 2013 Ultradent chloride Cord, Coltene silicone, stone Kalrock, microscope microscope
Products, Inc (manufacturer -Expasyl paste, Dentsply Sirona Kalabhai (manufacturer Software
not informed) Satelec not informed)
Goutham 11 and 21 Yes N/A N/A 25% Aluminum Magic Foam Addition Type IV dental Optical -Axiovision,
et al,22 2018 chloride Cord, Coltene silicone stone microscope microscope
(manufacturer (manufacturer (manufacturer (manufacturer Software
not informed) not informed) not informed) not informed)
Jain et al,24 Maxillary Yes Ultrapak, #1 Saline solution Expasyl paste, Addition Type IV dental Traveling Did not use
2018 and Ultradent Satelec silicone, Aquasil stone microscope,
mandibular Products, Inc soft putty/ Ultrarock, Weswox Optik
-Incisors regular set and Kalabhai
-Canines AquasilLv Ultra,
-Premolars Dentsply Sirona
-Molars
Kazemi Posterior Yes Ultrapak #1 15% Aluminum Expasyl paste, Condensation Type IV die Traveling Did not use
et al,25 2009 tooth Knitted, chloride, Stat Satelec silicone, stone, GC microscope,
Ultradent Germiphene Speedex, FujiRock Edmund Optics
Products, Inc Coltene
Thimmappa 36 e 46 Yes Ultrapak, - #000 10% Aluminum -Magic Foam Addition Did not use Stereomicroscope, Pro-Express,
et al,11 2018 Ultradent - #0 chloride Roeko, Cord, Coltene silicone, Ivoclar Lawrence and Media
Products, Inc - #1 Coltene -Merocel strip, Vivadent AG Mayo Cybernetics
- #2 Mystic, Conn
Prasanna Premolars Yes Ultradent #00 15.5% Ferric Expasyl paste, Addition Did not use Optical Did not
et al,12 2013 Products, Inc sulfate, Satelec silicone, Express stereomicroscope, use
Ultradent STD and Imprint Olympus
Products, Inc II garant, 3M
ESPE
Gupta N/A Yes Roeko stay- N/A Did not use -Magic Foam Polyether, Did not use Stereomicroscopic Image-Pro
et al,26 put, Coltene Cord, Coltene Impregnum (manufacturer not Express,
2013 -Expasyl paste, Soft, 3M ESPE informed) Media
Satelec Cybernetics

Martins et al THE JOURNAL OF PROSTHETIC DENTISTRY


4 Volume - Issue -

first evaluation of the sulcular width in the gypsum cast


Goutham et al., 2018 + ? ? – ? +
and the second evaluation of the sulcular width in the
Gupta et al., 2013 + ? ? – ? – impression. In the first stratum, the meta-analysis pre-
sented evidence that the GD was better in the control
Jain et al., 2018 – ? ? – ? –
groups where the displacement cord was used (P!.05).
kazemi et al., 2009 – ? ? – ? – In the second stratum, the meta-analysis did not present
statistical difference among the groups (P>.05). High
Prasanna et al., 2013 – ? ? – ? –
heterogeneity was observed among studies and sub-
Raghav et al., 2013 – ? ? – ? – groups (I2=99% and 65%). In the second stratum, the
“one study remove test” showed that the study of Pra-
Shrivastava et al., 2015 – ? ? – ? –
sanna et al12 influenced the heterogeneity. The test
Thimmappa et al., 2018 – ? ? – ? – showed that 92% of heterogeneity was reduced to 0%
when the study was removed.
Tiwari et al., 2018 – ? ? – ? –
In the third analysis, 9 data sets were evaluated
(Fig. 4C). The studies were divided based on the meth-
fo ion )
om t (d anc s)

ti as)

iti ias)

he )

s
s

Ot ias

ia
ia

rb odology used for evaluation: the first evaluation of the


bi

i
el n b

b
(a on b

b
on
e
io

sulcular width in a digital microscope image and the


ct

t
ec

da ec

ttr
rm
le

et
ou pe alm (se

second evaluation of the sulcular width with a micro-


( s

ta
er
ce ion

In com son ent


(p

scope and a metric scale. In the first stratum, the meta-


e
t

el

m
di ant n c era

e
n

s
es
Bl cip atio gen

analysis presented evidence that GD was better in the


tc
ss
on

ou
r
m ea
rti loc ce

control groups where the displacement cord was used


e
en

of nd

et
qu

pl
ng s a

(P!.05). In the second, the meta-analysis did not present


t
se

co
Al
om

a statistical difference between the groups (P>.05). High


nd

heterogeneity was observed among studies (I2=99%) and


Ra

pa

in
of

low among subgroups (I2=10%). For the “one study


ng
di

remove test,” none of the combinations led to a decrease


in
Bl

Figure 2. Risk-of-bias summary. in heterogeneity.


In the fourth analysis, 3 data sets were evaluated
concealment, blinding of participants and personnel, and (Fig. 4D). The studies that performed the evaluation of
incomplete outcome data were not found in the texts the sulcular width of the anterior tooth with a digital
presented by the authors. microscope image or a microscope and a metric scale
In the global analysis, all 9 studies were evaluated were selected. The meta-analysis presented evidence that
(Fig. 4A). The meta-analysis presented evidence that the the GD was better in the control groups where the
GD was better in the control groups where the displacement cord was used (P<.001). High heteroge-
displacement cord was used (P!.05). High heterogeneity neity among the studies was observed (I2=88%). For the
was observed among the studies (I2=99%). For the “one “one study remove test,” none of the combinations led to
study remove test”, none of the combinations led to a a decrease in heterogeneity.
decrease in heterogeneity. In the fifth analysis, 8 data sets were evaluated (Fig. 4E).
In the second analysis, 9 data sets were evaluated The studies were divided based on the methodology used
(Fig. 4B). The studies were divided based on the meth- to evaluate the sulcular width of teeth prepared for com-
odology used for the evaluation of the sulcular width: the plete crowns: the first prepared tooth - sulcular width

Random sequence generation (selection bias)


Allocation concealment (selection bias)
Blinding of participants and personnel (performance bias)
Blinding of outcome assessment (detection bias)
Incomplete outcome data (attrition bias)
Other bias

0 25 50 75 100
Bias (%)
Low risk of bias Unclear risk of bias High risk of bias

Figure 3. Risk-of-bias graph.

THE JOURNAL OF PROSTHETIC DENTISTRY Martins et al


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Control Experimental Mean Difference Mean Difference


Study or Subgroup Mean SD Total Mean SD Total Weight IV, Random, 95% CI IV, Random, 95% CI

1.1.1 GLOBAL
Goutham et al., 2018 0.44 0.112 15 0.3133 0.092 15 11.2% 0.13 (0.05, 0.20)
Gupta et al., 2013 0.233 0.082 20 0.175 0.0802 40 11.6% 0.06 (0.01, 0.10)
Jain et al., 2018 0.3197 0.1799 156 0.3653 0.1651 156 11.6% –0.05 (–0.08, –0.01)
Kazemi et al., 2009 0.46 0.03 10 0.34 0.04 10 11.7% 0.12 (0.09, 0.15)
Prasanna et al., 2013 0.215 0.011 16 0.265 0.02 16 11.8% –0.05 (–0.06, –0.04)
Raghav et al., 2013 0.5156 0.0876 25 0.3788 0.1598 50 11.4% 0.14 (0.08, 0.19)
Shrivastava et al., 2015 0.7403 0.0534 20 0.4568 0.0535 40 11.7% 0.28 (0.25, 0.31)
Thimmappa et al., 2018 0.85 0.45 30 0.74 0.6238 60 7.5% 0.11 (–0.12, 0.34)
Tiwari et al., 2018 0.79 0.14 30 0.56 0.09 30 11.4% 0.23 (0.17, 0.29)
Subtotal (95% CI) 322 417 100.0% 0.11 (0.01, 0.21)
2 2 2
Heterogeneity: τ =0.02; χ =601.53, df=8 (P<.001); I =99%
Test for overall effect: z=2.06 (P=.04)

Total (95% CI) 322 417 100.0% 0.11 (0.01, 0.21)


2 2 2
Heterogeneity: τ =0.02; χ =601.53, df=8 (P<.001); I =99%
Test for overall effect: z=2.06 (P=.04) –0.5 –0.25 0 0.25 0.5
Test for subgroup differences: Not applicable Favors Experimental Favors Control

Control Experimental Mean Difference Mean Difference


Study or Subgroup Mean SD Total Mean SD Total Weight IV, Random, 95% CI IV, Random, 95% CI
1.2.1 gypsum cast sulcular width evaluation
Goutham et al., 2018 0.44 0.112 15 0.3133 0.092 15 11.2% 0.13 (0.05, 0.20)
Jain et al., 2018 0.3197 0.1799 156 0.3653 0.1651 156 11.6% –0.05 (–0.08, –0.01)
Kazemi et al., 2009 0.46 0.03 10 0.34 0.04 10 11.7% 0.12 (0.09, 0.15)
Raghav et al., 2013 0.5156 0.0876 25 0.3788 0.1598 50 11.4% 0.14 (0.08, 0.19)
Shrivastava et al., 2015 0.7403 0.0534 20 0.4568 0.0535 40 11.7% 0.28 (0.25, 0.31)
Tiwari et al., 2018 0.79 0.14 30 0.56 0.09 30 11.4% 0.23 (0.17, 0.29)
Subtotal (95% CI) 256 301 69.1% 0.14 (0.03, 0.25)
Heterogeneity: τ2=0.02; χ2=194.32, df=5 (P<.001); I2=97%
Test for overall effect: z=2.59 (P=.009)

1.2.2 impression material sulcular width evaluation


Gupta et al., 2013 0.233 0.082 20 0.175 0.0802 40 11.6% 0.06 (0.01, 0.10)
Prasanna et al., 2013 0.215 0.011 16 0.265 0.02 16 11.8% –0.05 (–0.06, –0.04)
Thimmappa et al., 2018 0.85 0.45 30 0.74 0.6238 60 7.5% 0.11 (–0.12, 0.34)
Subtotal (95% CI) 66 116 30.9% 0.02 (–0.08, 0.11)
Heterogeneity: τ2=0.01; χ2=23.80, df=2 (P<.001); I2=92%
Test for overall effect: z=0.33 (P=.74)

Total (95% CI) 322 417 100.0% 0.11 (0.01, 0.21)


Heterogeneity: τ2=0.02; χ2=601.53, df=8 (P<.001); I2=99%
Test for overall effect: z=2.06 (P=.04) –0.5 –0.25 0 0.25 0.5
Test for subgroup differences: χ2=2.86, df=1 (P=.09), I2=65.0% Favors Experimental Favors Control

B
Figure 4. A, 1.1.1 Global analysis. B, Analysis 1.2.1 gypsum cast sulcular width evaluation and 1.2.2 impression material sulcular width evaluation.

evaluation in the gypsum cast - digital microscope image, microscope and a metric scale. In the first stratum, the
the second prepared tooth - sulcular width evaluation in meta-analysis presented evidence that the GD was better
the gypsum cast - microscope and a metric scale, and the in the control groups where the displacement cord was
third prepared tooth - sulcular width evaluation in the used (P!.05). In the second and third strata, the meta-
impression material - digital microscope image or analysis did not present a statistical difference between

Martins et al THE JOURNAL OF PROSTHETIC DENTISTRY


6 Volume - Issue -

Control Experimental Mean Difference Mean Difference


Study or Subgroup Mean SD Total Mean SD Total Weight IV, Random, 95% CI IV, Random, 95% CI
1.3.1 sulcular width evaluation with digital microscope image
Goutham et al., 2018 0.44 0.112 15 0.3133 0.092 15 11.2% 0.13 (0.05, 0.20)
Gupta et al., 2013 0.233 0.082 20 0.175 0.0802 40 11.6% 0.06 (0.01, 0.10)
Raghav et al., 2013 0.5156 0.0876 25 0.3788 0.1598 50 11.4% 0.14 (0.08, 0.19)
Shrivastava et al., 2015 0.7403 0.0534 20 0.4568 0.0535 40 11.7% 0.28 (0.25, 0.31)
Thimmappa et al., 2018 0.85 0.45 30 0.74 0.6238 60 7.5% 0.11 (–0.12, 0.34)
Subtotal (95% CI) 110 205 53.4% 0.15 (0.03, 0.26)
Heterogeneity: τ2=0.01; χ2=82.35, df=4 (P<.001); I2=95%
Test for overall effect: z=2.56 (P=.01)
1.3.2 sulcular width evaluation with microscope and metric scale
Jain et al., 2018 0.3197 0.1799 156 0.3653 0.1651 156 11.6% –0.05 (–0.08, –0.01)
Kazemi et al., 2009 0.46 0.03 10 0.34 0.04 10 11.7% 0.12 (0.09, 0.15)
Prasanna et al., 2013 0.215 0.011 16 0.265 0.02 16 11.8% –0.05 (–0.06, –0.04)
Tiwari et al., 2018 0.79 0.14 30 0.56 0.09 30 11.4% 0.23 (0.17, 0.29)
Subtotal (95% CI) 212 212 46.6% 0.06 (–0.05, 0.17)
Heterogeneity: τ2=0.01; χ2=174.80, df=3 (P<.001); I2=98%
Test for overall effect: z=1.06 (P=.29)
Total (95% CI) 322 417 100.0% 0.11 (0.01, 0.21)
Heterogeneity: τ2=0.02; χ2=601.53, df=8 (P<.001); I2=99%
Test for overall effect: z=2.06 (P=.04) –0.5 –0.25 0 0.25 0.5
Test for subgroup differences: χ2=1.11, df=1 (P=.29), I2=10.0%
Favors Experimental Favors Control

C
Control Experimental Mean Difference Mean Difference
Study or Subgroup Mean SD Total Mean SD Total Weight IV, Random, 95% CI IV, Random, 95% CI
1.4.1 anterior tooth - sulcular width evaluation with digital microscope image or microscope and metric scale
Goutham et al., 2018 0.44 0.112 15 0.3133 0.092 15 30.2% 0.13 (0.05, 0.20)
Shrivastava et al., 2015 0.7403 0.0534 20 0.4568 0.0535 40 37.1% 0.28 (0.25, 0.31)
Tiwari et al., 2018 0.79 0.14 30 0.56 0.09 30 32.7% 0.23 (0.17, 0.29)
Subtotal (95% CI) 65 85 100.0% 0.22 (0.13, 0.30)
Heterogeneity: τ2=0.01; χ2=16.19, df=2 (P<.001); I2=88%
Test for overall effect: z=4.97 (P<.001)
Total (95% CI) 65 85 100.0% 0.22 (0.13, 0.30)
Heterogeneity: τ2=0.01; χ2=16.19, df=2 (P<.001); I2=88%
Test for overall effect: z=4.97 (P<.001)
–0.5 –0.25 0 0.25 0.5
Test for subgroup differences: Not applicable
Favors Experimental Favors Control

D
Figure 4. (Continued). C, Analysis 1.3.1: sulcular width evaluation with digital microscope image; 1.3.2: sulcular width evaluation with microscope and
metric scale. D, Analysis 1.4.1: anterior tooth (sulcular width evaluation with digital microscope image or microscope and metric scale).

the groups (P>.05). High heterogeneity was observed image, the second Expasyl paste, Satelec - sulcular width
among studies and subgroups (I2=99% and 60.4%). In the evaluation in the gypsum cast - microscope and a metric
first and third strata, the “one study remove test” showed scale, the third Expasyl paste, Satelec- sulcular width
that Shrivastava et al20 and Prasanna et al12 influenced evaluation in the impression material - digital microscope
heterogeneity. The test showed that a high heterogeneity image or microscope and a metric scale, the fourth Magic
of 94% and 92% was reduced to 0% when each study was Foam Cord, Coltene - sulcular width evaluation in the
removed. gypsum cast - digital microscope image or microscope and
In the sixth analysis, 12 data sets were evaluated a metric scale, and the fifth Magic Foam Cord, Coltene -
(Fig. 4F). The studies were divided based on the cordless sulcular width evaluation in the impression material -
material and the methodology used to evaluate the digital microscope image. In the first, second, third, and
sulcular width: the first Expasyl paste, Satelec- sulcular fifth strata, the meta-analysis did not present a statistical
width evaluation in the gypsum cast - digital microscope difference between the groups (P>.05). In the fourth

THE JOURNAL OF PROSTHETIC DENTISTRY Martins et al


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Control Experimental Mean Difference Mean Difference


Study or Subgroup Mean SD Total Mean SD Total Weight IV, Random, 95% CI IV, Random, 95% CI
1.5.1 prepared tooth - gypsum cast sulcular width evaluation - digital microscope image
Goutham et al., 2018 0.44 0.112 15 0.3133 0.092 15 12.6% 0.13 (0.05, 0.20)
Raghav et al., 2013 0.5156 0.0876 25 0.3788 0.1598 50 12.9% 0.14 (0.08, 0.19)
Shrivastava et al., 2015 0.7403 0.0534 20 0.4568 0.0535 40 13.3% 0.28 (0.25, 0.31)
Subtotal (95% CI) 60 105 38.8% 0.19 (0.07, 0.30)
Heterogeneity: τ2=0.01; χ2=31.03, df=2 (P<.001); I2=94%
Test for overall effect: z=3.14 (P=.002)
1.5.2 prepared tooth - gypsum cast sulcular width evaluation - microscope and metric scale
Jain et al., 2018 0.3197 0.1799 156 0.3653 0.1651 156 13.2% –0.05 (–0.08, –0.01)
Kazemi et al., 2009 0.46 0.03 10 0.34 0.04 10 13.2% 0.12 (0.09, 0.15)
Subtotal (95% CI) 166 166 26.4% 0.04 (–0.12, 0.20)
Heterogeneity: τ2=0.01; χ2=43.38, df=1 (P<.001); I2=98%
Test for overall effect: z=0.45 (P=.65)
1.5.3 prepared tooth - impression material sulcular width evaluation - digital microscope image or microscope and metric scale
Gupta et al., 2013 0.233 0.082 20 0.175 0.0802 40 13.1% 0.06 (0.01, 0.10)
Prasanna et al., 2013 0.215 0.011 16 0.265 0.02 16 13.4% –0.05 (–0.06, –0.04)
Thimmappa et al., 2018 0.85 0.45 30 0.74 0.6238 60 8.4% 0.11 (–0.12, 0.34)
Subtotal (95% CI) 66 116 34.9% 0.02 (–0.08, 0.11)
Heterogeneity: τ2=0.01; χ2=23.80, df=2 (P<.001); I2=92%
Test for overall effect: z=0.33 (P=.74)
Total (95% CI) 292 387 100.0% 0.09 (–0.02, 0.20)
Heterogeneity: τ2=0.02; χ2=551.04, df=7 (P<.001); I2=99%
Test for overall effect: z=1.67 (P=.09)
–0.5 –0.25 0 0.25 0.5
Test for subgroup differences: χ2=5.05, df=2 (P=.08), I2=60.4%
Favors Experimental Favors Control

E
Figure 4. (Continued). E, Analysis 1.5.1: prepared tooth (gypsum cast sulcular width evaluation; digital microscope image); 1.5.2: prepared tooth
(gypsum cast sulcular width evaluation; microscope and metric scale); 1.5.3: prepared tooth (impression material sulcular width evaluation; digital
microscope image or microscope and metric scale).

stratum, the meta-analysis presented evidence that the prepared tooth, thus explaining the high heterogeneity
GD was better in the control groups where the displace- found.15,18,24,26
ment cord was used (P<.001). Heterogeneity was high GD with cords14-18 is still considered the gold-
among the studies (I2=99%) and substantial among the standard technique. In this meta-analysis, displacement
subgroups (I2=56.8%). The “one study remove test” was cord resulted in increased GD when compared with the
performed only for the fourth stratum because the other cordless technique. Taken together, the current evidence
strata had only 2 studies. However, none of the combi- supports the general superiority of the cord technique for
nations led to a decrease in heterogeneity. increased gingival displacement. However, limitations of
the literature include an incomplete report of the GD
DISCUSSION
protocols used, such as cord manufacturer, cord thick-
Gingival displacement (GD) is a procedure that aims to ness, and aluminum chloride concentration.12,19-22,24,26
dry and allow access of the impression material to the Therefore, future studies in the field should report
gingival sulcus33 by moving the adjacent tissues laterally these data clearly.
from the prepared tooth.15,17 The goal is to obtain a Although a goal of GD is to provide a dry gingival
sulcular width greater than 0.2 mm, making it possible sulcus,33 the use of a dry cord leads to rupture and
for the impression material, or scanner, to copy the tooth desquamation of the sulcular and junctional epithe-
structure14,16,33 and provide adequate thickness of the lium,33,34 leading to increased fluid flow.35 Therefore, a
impression material to resist distortion or tearing.14-18,33 chemomechanical method using cords impregnated with
Therefore, the choice of an appropriate displacement either hemostatic, vasoconstrictor, or astringent agents
method is a critical step. has been recommended.11,12,19-27 In this meta-analysis,
Most studies reported obtaining a sulcular width astringent aluminum chloride was used for GD, except
greater than 0.2 mm11,12,19-22,24-26 independently of for the study by Gupta et al,26 who used a dry
gingival thickness, sulcus depth, or location of the displacement cord.

Martins et al THE JOURNAL OF PROSTHETIC DENTISTRY


8 Volume - Issue -

Control Experimental Mean Difference Mean Difference


Study or Subgroup Mean SD Total Mean SD Total Weight IV, Random, 95% CI IV, Random, 95% CI
1.6.1 Expasyl - gypsum cast sulcular width evaluation - digital microscope image
Raghav et al., 2013 0.5156 0.0876 25 0.4568 0.1457 25 8.3% 0.06 (–0.01, 0.13)
Shrivastava et al., 2015 0.7403 0.0534 20 0.4983 0.0261 20 8.6% 0.24 (0.22, 0.27)
Subtotal (95% CI) 45 45 16.9% 0.15 (–0.03, 0.33)
Heterogeneity: τ2=0.02; χ2=25.18, df=1 (P<.001); I2=96%
Test for overall effect: z=1.67 (P=.09)
1.6.2 Expasyl - gypsum cast sulcular width evaluation - microscope and metric scale
Jain et al., 2018 0.3197 0.1799 156 0.3653 0.1651 156 8.5% –0.05 (–0.08, –0.01)
Kazemi et al., 2009 0.46 0.03 10 0.34 0.04 10 8.6% 0.12 (0.09, 0.15)
Subtotal (95% CI) 166 166 17.1% 0.04 (–0.12, 0.20)
Heterogeneity: τ2=0.01; χ2=43.38, df=1 (P<.001); I2=98%
Test for overall effect: z=0.45 (P=.65)
1.6.3 Expasyl - impression material sulcular width evaluation - digital microscope image or microscope and metric scale
Gupta et al., 2013 0.233 0.082 20 0.151 0.069 20 8.5% 0.08 (0.04, 0.13)
Prasanna et al., 2013 0.215 0.011 16 0.265 0.02 16 8.6% –0.05 (–0.06, –0.04)
Subtotal (95% CI) 36 36 17.1% 0.01 (–0.12, 0.14)
Heterogeneity: τ2=0.01; χ2=28.71, df=1 (P<.001); I2=97%
Test for overall effect: z=0.21 (P=.83)
1.6.4 Magic Foam - gypsum cast sulcular width evaluation - digital microscope image or microscope and metric scale
Goutham et al., 2018 0.44 0.112 15 0.3133 0.092 15 8.2% 0.13 (0.05, 0.20)
Raghav et al., 2013 0.5156 0.0876 25 0.3008 0.1351 25 8.3% 0.21 (0.15, 0.28)
Shrivastava et al., 2015 0.7403 0.0534 20 0.4154 0.0397 20 8.6% 0.32 (0.30, 0.35)
Tiwari et al., 2018 0.79 0.14 30 0.56 0.09 30 8.4% 0.23 (0.17, 0.29)
Subtotal (95% CI) 90 90 33.6% 0.23 (0.14, 0.32)
Heterogeneity: τ2=0.01; χ2=32.62, df=3 (P<.001); I2=91%
Test for overall effect: z=5.07 (P<.001)
1.6.5 Magic Foam - impression material sulcular width evaluation - digital microscope image
Gupta et al., 2013 0.233 0.082 20 0.199 0.085 20 8.4% 0.03 (–0.02, 0.09)
Thimmappa et al., 2018 0.85 0.45 30 0.36 0.13 30 6.8% 0.49 (0.32, 0.66)
Subtotal (95% CI) 50 50 15.3% 0.25 (–0.19, 0.70)
Heterogeneity: τ2=0.10; χ2=25.96, df=1 (P<.001); I2=96%
Test for overall effect: z=1.12 (P=.26)
Total (95% CI) 387 387 100.0% 0.15 (0.05, 0.24)
Heterogeneity: τ2=0.03; χ2=994.08, df=11 (P<.001); I2=99%
Test for overall effect: z=3.00 (P=.003)
Test for subgroup differences: χ2=9.27, df=4 (P=.05), I2=56.8% –0.5 –0.25 0 0.25 0.5
Favors Experimental Favors Control

F
Figure 4. (Continued). F, Analysis 1.6.1: Expasyl paste (Satelec; gypsum cast sulcular width evaluation; digital microscope image), 1.6.2: Expasyl
paste (Satelec; gypsum cast sulcular width evaluation; microscope and metric scale), 1.6.3: Expasyl paste (Satelec; impression material sulcular width
evaluation; digital microscope image or microscope and metric scale), 1.6.4: Magic Foam Cord (Coltene; gypsum cast sulcular width evaluation; digital
microscope image or microscope and metric scale), and 1.6.5: Magic Foam Cord (Coltene; impression material sulcular width evaluation; digital
microscope image).

Despite the increased GD with cords observed in this be injected and maintained for about 2 minutes16 into the
meta-analysis, the pressure applied during the insertion gingival sulcus in a mechanochemical technique.15-18
of cords can cause lesions to the epithelial attachment This material contains 15% aluminum chloride as a he-
and induce bleeding during removal.15-18 This damage mostatic agent and performs gingival displacement
tends to be clinically and histologically reversible within 2 through the hygroscopic expansion of kaolin16,25 and
weeks18 For this reason, alternative displacement mate- appears to be the most effective in its class. In the sixth
rials have been developed. group of this meta-analysis, the GD obtained by this
Among the materials used in the cordless methods, material, even when evaluated by various measurement
Expasyl paste (Satelec) is formulated as a viscous paste to methodologies, was not statistically different (P>.05)

THE JOURNAL OF PROSTHETIC DENTISTRY Martins et al


- 2019 9

when compared with that of the displacement cord Limitations of the present systematic review and
(Fig. 4F). Moreover, this material caused fewer lesions to meta-analysis may explain the heterogeneity observed.
the gingival tissues18 and induced decreased levels of Studies have reported on anterior and posterior teeth
inflammatory mediators (interleukin 1ß, interleukin 6, with or without tooth preparation. Several studies did
and tumor necrosis factor a) in the crevicular fluid.36 not report the thickness of the cord used, making it
However, this material may be more effective under impossible to compare different cord thicknesses and
specific conditions such as when the sulcus is flexible and the cordless technique. Additionally, various method-
the finish line is shallow.16,17,26,37 ologies were used to evaluate sulcular width, preclud-
In this systematic review, aluminum chloride in con- ing, therefore, adequate comparison among the
centrations between 5% and 25% was the most used different studies. Enhanced methodological standardi-
astringent. The astringent component of the displace- zation of sampling, material, and method of reporting,
ment pastes acts solely on the superficial layer of the especially the criteria for gingival displacement mea-
mucosa33,38 and reduces the free gingival margin volume surements, are still needed.
through chemical hemostasis,33 exudation of crevicular
fluid, and enhanced precipitation of blood proteins, CONCLUSIONS
which inhibit bleeding from gingival microvessels.
However, these materials may affect the polyether Within the limitations imposed on this systematic review
impression material if aluminum chloride residue is not and meta-analysis, the following conclusions were
removed14,37 and should not be used in patients with an drawn:
allergy to aluminum.16 For these reasons, astringent-free 1. The cord technique resulted in increased displace-
cordless materials have also been developed. ment when compared with the cordless technique.
Magic Foam Cord (Coltene) is a nonhemostatic 2. Expasyl paste was the most effective cordless
gingival displacement system that contains a polyvinyl material.
siloxane expandable material,14-17 which is applied 3. Evaluation of the sulcular width with a digital mi-
around the margin of the prepared tooth while being croscope image obtained from a sectioned gypsum
held under pressure with a compression cap (ROEKO cast is an adequate and versatile experimental
Comprecap; Coltene) for 5 minutes before the impression methodology for measuring displacement.
procedure.14,16,19 The delay allows the expansion of the 4. Evaluation of the sulcular width directly on the
material inside the gingival sulcus.14,16 Limitations of this impression material is a limited methodology for
material include limited clinical indications, lack of he- measuring displacement.
mostatic effects, and reduced efficacy on a subgingival
finish line.16 In the studies in the present meta-analysis,
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Corresponding author:
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Today 2018;10:7. Dr Felipe Villela Martins
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