ANNEXURE I TERMS OF REFERENCE

ANNEXURE I
TERMS OF REFERENCE
 TOR prescribed by MoEF & CC for this sector will be taken in to account.
M/s. VIHITA CHEM PVT LTD (UNIT-III)

1
ANNEXURE II
DETAILS OF PRODUCTS
Sr. Name of the Products CAS No. QUANTITY End-use of the
no. products
MT/MONTH
GROUP-1 (Sr. NO:- 1 to 3) (70 MT/Month)
1. 2,3,4,5–bis-O-[1-Methyl Ethyl 20880-92-6 70 For Topiramate

idene]B-D-Fructopyranose
(API)
2. Di Methyl Formamide Di Methyl 4637-24-5 For Imatinib (API)

Acetal
3. 4-Methyl Catechol Di-acetic acid 52589-39-6 For Watermelone

Dimethyl ester Ketone
(FRAGRANCE)
GROUP-2 (Sr No:-4 to 8 ) (40 MT/Month)
4. 4-Methyl Catechol 452-86-8 40 For Watermelon

Ketone
(FRAGRANCE)
5. Methylene dioxy phenol 533-31-3 For Paroxetine (API)
6. 4-Chloro-4’Hydroxy 42019-78-3 For Fenofibrate

Benzophenone (API)
7. 2-Bromo Veratryl Bromide 53207-004 For Pinaverium

Bromide (API)
8. 7-Ethyl tryptophol 41340-36-7 For Etodolac (API)
GROUP-3 (Sr No:-9 to 53) (25 MT/Month)
9. Di Methyl Formamide Di Iso 18503-89-4 25 For Cocaine (API)

Propyl Acetal
10. 4-Methoxy Benzaldehyde 2186-92-7 For

dimethyl Acetal Paclitaxel/Octinoxate
(API)
11. Benzaldehyde dimethyl Acetal 1125-88-8 For Rosuvastatin

(API)

2
ANNEXURE II
12. Dimethyl Acetamide Dimethyl 018871-66-4 For Zaleplon (API)

Acetal
13. O-Benzyl hydroxyl amine 2687-43-6 For Larsartan (API)

Hydrochloride
14. Endo-9-methyl-9- 76272-56-5 For Granisetron

azabicyclo[3,3,1]nonane 3-amine (API)
15. 2 3 Dihydrofuran 1191-99-7 For Etodolac

(API)
16. 2-Amino-4-fluoro Benzophenone 3800-06-4 For Pitavastatin (API)
17. 2-(2-ethoxy phenoxy)ethyl amine 64464-07-9 For Tamsulosin (API)

HCL
18. 2-(2-ethoxy phenoxy)ethyl amine 6781-17-5 For Tamsulosin (API)
19. N-(4-cyanophenyl)-glycin 42288-26-6 For Dabigatran (API)
20. 1-(2,'5' Dimethoxy phenyl amino 3600-87-1 For Midodrine (API)

ethanol)
21. Guanidine hydrochloride 50-01-1 For Triazine (API)
22. Guanidine Nitrate 506-93-4 For Trimethoprim

(API)
23. Guanidine thiocyante 593-84-0 For Triazine (API)
24. O-benzyl hydroxyl amine 2687-43-6 For Azaindoles (API)
25. Syringaldazine 14414-32-5 For Cholrine Test

(API)
26. 3-amino-2-thiophenecarboxylic 55341-87-2 For Tenoxicam (API)

acid
27. ethyl 2-(3-cyano-4- 125971-96-2 For Atorvastatin

isobutoxyphenyl)-T-oxo-N,B- (API)
diphenylbenzenebutanamide

3
ANNEXURE II
28. Sulfamerazine 127-79-7 For Antibiotic &

Antimicrobial (API)
29 2-amino-4-methylpyrimidine 108-52-1 For Sulfamerazine

(API)
30 Methyl-2-amino-3-nitrobenzoate 57113-91-4 For Candesartan

(API)
31. Guanidine carbonate 593-85-1 For Triazine (API)
32. N-hydroxy phthalimide 524-38-9 For Catalyst

Oxidation Reaction
33 Alpha –Bromo -2-Chloro Phenyl 85259-19-4 For Clopidogrel

Acetic Acid Methyl Ester (API)
34 4-Methoxy-3- 592542-51-3 For Oncology

nitrobenzylsulfonylacetic acid
(API)
35 3,4-Dihydroxy Benzoic Acid 99-50-3 For Protochuic Acid

(API)
36 3,4- Dihydroxy Benzoic Acid 2150-43-8 For Erlotinib

Methyl ester
(API)
37 Piperonylic Methyl Ester 326-56-7 For Fragrance
Intermediate
38 Ethyl 3-[(pyridin-2-yl)-amino]- 103041-38-9 For Dabigatran

propanoate (API)
39 3-nitro-4-methylamino benzoic 41263-74-5 For Dabigatran

acid (API)
40 Hydroquinone dimethyl ester 150-78-7 For Midodrine (API)
41 Malonic Acid Methyl Ester 38330-80-2 For Gycosylation

Potassium salt (API)
42 (1R,2R)-1,2 Cyclohexane 46022-05-3 For Lurasidon Hcl

Dicarboxylic Acid (API)
43 1-Methylindazole-3-Carboxylic 50890-83-0 For Garnisetron Hcl

4
ANNEXURE II
acid (API)
44 Isovanillic Acid 645-08-9 For Galantamine

(API)
45 2-Methyl-3-Oxo-Pentanoate 759-66-0 For Etodolac (API)
46 2-(2-ethoxy phenoxy)-mesylate 106463-17-6 For Tamsilosin HCl

(Speciality Chemical)
47 3-(((2-methoxy-2- 106820-63-7 For Tenoxicam (API)

oxoethyl)amino)-sulfonyl)-2-
thiopenecarboxylic acid methyl
ester
48 Methyl-6-methylnicotinate 2519-37-1 For Etoricoxib (API)
49 4-[(4-Methyl-1-piperazinyl)- 106261-48-7 For Lematinib (API)

methyl]-benzoic acid
50 2-(((2'-cyano-(1,1'biphenyl)-4-yl)- 139481-28-0 For Cilexetile (API)

methyl)amino)-3-nitro benzoic
acid)
51 Ndlic anhydride (endo- cis- 3853-88-1 For Lurasidone Hcl

bicyclo-(2.2.1)-5-heptane-2,3- (API)
dicarboxylic acid)
52 4- Methoxy-3-(3- 895240-50-3 For Aliskiren (API)

methoxypropoxy) benzoic acid
53 3- cyclopropyl-3-oxo Propionic 32249-35-7 For Pitavastatin (API)

Acid Methyl Ester
GROUP-4 (Sr No:-54To 127) (25 MT/Month)
54 4-Hydroxy Benzyl Alcohol 623-05-2 25 For Bisoprolol

Fumarate (API)
55 2,4,6 TrimethoxyBenzaldehyde 830-79-5 For Oncology

(API)
56 4-Isopropyl catechol 2138-43-4 For Fragrance

Intermediate

5
ANNEXURE II
57 3-Methoxy Phenol 150-19-6 For Antioxidants

(API)
58 Veratryl Alcohol 93-03-8 For Pinaverium

Bromide (API)
59 3,4 Dihydroxy Benzaldehyde 139-85-5 For Protochuic Acid

(API)
60 4-Propyl Catechol 2525-02-2 For Fragrance
Intermediate
61 (3S,4R)-4-(4-Fluorophenyl)-3- 105812-81-5 For Paroxetine (API)

hydroxymethyl-1-
methylpiperidine(-alcohol)
62 3 –MethoxyPropiophenone 37951-49-8 For Tapentadol (API)
63 4-Hydroxy Benzaladehyde 123-08-0 For Bisoprolol

Fumarate (API)
64 Piperonyl Alcohol 495-76-1 Antioxidants (API)
65 3,4-Dimethoxy phenol 2033-89-8 For Thalicarpine

(API)
66 4- Methyl Guaiacol 93-51-6 For Fragrance
Intermediate
67 Isovanillyl Alcohol 4383-06-6 Aliskiren (API)
68 3-Methoxy benzyl alcohol 6971-51-3 Sarpogrelate (API)
69 2,5-dimethoxy Benzaldehyde 93-02-7 Midodrine (API)
70 5-Nitrovanillin 6635-20-7 Entacapone (API)
71 4-Hydroxy Anisole 150-76-5 For Fragrance
Intermediate
72 Salicylaldehyde 090-02-8 Midodrine (API)

6
ANNEXURE II
73 Isovanillin 621-59-0 For Galantamine

(API)
74 Watermelone ketone 28940-11-6 For Perfumes

(Fragrance)
75 (1R,2R)-1,2- 65376-05-8 For Lurasidone Hcl

cyclohexanedimethanol (API)
76 3’,4’-(methylenedioxy)- 3162-29-6 For Paroxetine Hcl

acetophenone (API)
77 3,4-dihyroxy-5-nitro- 116313-85-0 For Enatcapone (API)

benzaldehyde
78 2,4- di Hydroxy Benzophenone 131-56-6 For Antioxidants

(API)
79 2-hydroxy benzyl alcohol 90-01-7 For Fragrance
Intermediate
80 N-benzyl-4- 22065-85-6 For Donepezil (API)

piperidinecarboxaldehyde
81 5,6- Dimethoxy indanone 2107-69-9 For Donepezil (API)
82 3-(1-Piperaziny)-1,2- 87691-87-0/ For Ziprasidone

Benzisoxazole/Hydrochloride 87691-88-1 (API)
83 5-Chloroethyl-6-Chloro-2- 118289-55-7 For Ziprasidone

Oxindole (API)
84 4-[(4-Methyl-1-piperazinyl)- 106261-64-7 For Imatinib (API)

methyl]-benzoyl chloride
dihydrochloride
85 1-(Benzo (d)(1,3)dioxol-5-yl) 6329-73-3 For Proline (API)

)ethanol
86 2 -Bromo 2’,5’ – 1204-21-3 For Midodrine (API)

dimethoxyacetophenone
87 (1R,2R)-1-2-bis (methane 186204-35-3 For Lurasidone Hcl

sulfonyloxy methyl) cyclohexane (API)
88 Tert-butyl(4-bromophenyl) 639520-70-0 For Protecting Group

Methylcarbamate

7
ANNEXURE II
89 (2-cyclopropyl-4-(4- 121660-11-5 For Pitavastatin (API)

fluorophenyl)quinolone-
3yl)methanol
90 2-Bromo-3’-Chloro – 34911-51-8 For Bupropion Hcl
Propiophenone (API)
91 3- Bromo- 4-Hydroxy 2973-78-6 For Bromoxynil

Benzaldehyde (API)
92 3,4-(methylenedioxy) bromo 2635-13-4 4-Bromo 1,2-

benzene Methylene Dioxy
Benzene (Speciality
Chemical)
93 3-Methoxy Benzyl chloride 824-98-6 Sarpogrelate (API)
94 4- Chloro Guaiacol 16766-30-6 For Fragrance
Intermediate
95 4- Chloro Veratrole 16766-27-1 For Reactant

96 2-Bromo-4- Chloro Phenol 695-96-5 For Reactant

97 4- Bromo Anisole 104-92-7 4-Bromo –(3-Methyl

Phenol)
Methanamine
98 4-BromoPhenetole 588-96-5 For irritability

(Fragrance)
99 Endo-9-methyl-9- 135906-03-5 For Granisetron Hcl

azabicyclo[3,3,1]nonane 3-amine Int. (API)
2 HCL
100 2-Bromo-4-Cyanophenol 82380-17-4 For 2-Bromo -4-

Hydroxy -
Benzonitrite
101 2-Chloro-4,6-dimethoxy-[1,3,5]- 3140-73-6 For Pemetrexed

triazine Disodium (API)

8
ANNEXURE II
102 Bicyclo[2.2.1]hep-tane-2,3-exo- 14805-29-9 For Lurasidone (API)

dicarboximide
103 4-Bromo Phenol 106-41-2 For Stilled Reaction

104 2-(2-ethoxy phenoxy) ethyl 3259-03-8 For Tamsulosin (API)

bromide
105 Ethyl-3[1-(3 amino-4-(methyl 212322-56-0 For Dabigatran (API)

amino)-phenyl)-n-(pyridine-2-yl)-
foramido)proponate]
106 Ethyl-n-[2-((4-cyanophenyl)- 211915-84-3 For Dabigartan

amino)-methyl-1-methyl-1H- (API)
benzimidazol-5-yl)-carbonyl-n-
pyridine-2-yl-b-alanimate030
107 6-chloro 2-oxindole 56341-37-8 For Ziprasidone

(API)
108 6-chloro-5-(chloroactyl)-1-3- 118307-04-3 For Ziprasidone

dihydro-2H-indole-2-one (API)
109 3,4-(methylenedioxy)-toluene 7145-99-5 For Sitaxentan
(API)
110 2-chloro-4,6- 18093-05-5 For Fenoldopam

dimethoxybenzaldehyde Mesylate (API)
111 2-chloro-2',5'-dimethoxy 1204-22-4 For Midodrine (API)

Acetophenone
112 4-fluoro-alpha-(2-methyl-1- 125971-96-2 For Atorvastatin

oxopropyl)-t-oxo- (API)
N,B,Diphenylbenzenebutanamide
113 5-Bromo-6-bromomethyl-1,3- 5434-47-9 For Iloperidone (API)

benzodioxole
114 6-Fluoro-3-(4-piperidinyl)1,2- 84163-77-9 For Resperidone

benzisoxazole (API)
115 2,4-dimethoxy benzyl chloride 55791-52-1 For Coumestan


9
ANNEXURE II
116 methyl-4-(Bromomethyl)- 2417-72-3 For Eprosartan (API)

benzoate
117 1,2,3,4- tetrahydro-9-methyl-4H- 27387-31-1 For Ondansetron

carbazol-4-one (API)
118 4,5-dimethoxy-2- nitro toluene 7509-11-7 For Chemical

Ingredient (Speciality
Chemical)
119 Alpha-bromo-ortho-chloro-phenyl 29270-30-2 For Clopidogrel

acetic acid (API)
120 3,4-(Dimethoxy)-6-methylbenzyl 34523-76-7 For Antibiotics

chloride (API)
121 Anisole 100-66-3 For Fragrance

Intermediate
122 Veratrol 91-16-7 For Salmeterol Int.

(API)
123 Vanillin 121-33-5 For Vanilla Bean

(API)
124 Ethyl Vanillin 121-32-4 For Chocolate

&Antioxidants (API)
125 3,4-methylenedioxy 120-57-0 For Tadalafil Int.

Benzaldehyde (piperonal) (API)
126 1-[3-(benzyloxy)propyl]-5- 1375180-30-5 For Silodosin (API)

formylindoline-7-carbonitrile
127 Dimethylformamide di-tert-butyl 36805-97-7 For Int. Veterinary
Acetal Uses (API)
GROUP-5 (Sr No:- 128 to 209) (15 MT/Month)
128 AfatinibDimaleate 850140-73-7 15 For Metastatic

(pharma)
129 Arbutin 497-76-7 For Glycoside

(pharma)
130 Agomelatine 138112-76-2 For Antidepressant

(pharma)

10
ANNEXURE II
131 Apixaban 503612-47-3 For Anticoagulant

(pharma)
132 Aripiprazole 129722-12-9 For Antipsychotic

(pharma)
133 Asenapine 65576-45-6 For Schizophrenia

(pharma)
134 Axitinib 319460-85-0 For Carcinoma

(pharma)
135 Azilsartan 147403-03-0 For Hypertension

(pharma)
136 Abacavir Sulfate 188062-50-2 For HIV Medications

(pharma)
137 Atorvastatin Calcium 134523-03-8 For Cardiovascular

Diesease (pharma)
138 Bupropion HCL 31677-93-7 For Depressive Order

(pharma)
139 Bisoprolol Fumarate 104344-23-2 For Antihypertensive

(pharma)
140 Bazedoxifene 198481-32-2 For Cancer (pharma)
141 Canagliflozin 842133-18-0 For Diabetes

(pharma)
142 Candesartan Cilexetil 145040-37-5 For Angiotensin

(pharma)
143 Celecoxib 169590-42-5 For Non-Steroidal

&Anti-inflammatory
(pharma)
144 Clopidogrel sulfate 120202-66-6 For Antiplatelet

(pharma)
145 Dabigatran 211915-06-9 For Anticoagulant

(pharma)
146 Dapagliflozin 461432-26-8 For Glycemia

(pharma)

11
ANNEXURE II
147 Darifenacin 133099-04-4 For Overative

Bladder (pharma)
148 Donepezil 120014-06-4 For Dementia

(pharma)
149 Dronedarone 141626-36-0 For atrial fibrillation

(pharma)
150 Desvenlafaxine Succinate 386750-22-7 For Depressive

monohydrate Disorder (pharma)
151 Duloxetine Hydrochloride 136434-34-9 For Depression

&Anxiety (pharma)
152 Erlotinib 183321-74-6 For Cancer (pharma)
153 Etoricoxib 202409-33-4 For Pain & Swelling

(pharma)
154 Etodolac 41340-25-4 For Arthritis

(pharma)
155 Escitalopram oxalate 219861-08-2 For Depression &

Anxiety (pharma)
156 Febuxostat 144060-53-7 For Arthritis

(pharma)
157 Felodipine 72509-76-3 For Hypertension

(pharma)
158 Fluconazole 86386-73-4 For Antifungal

(pharma)
159 Fenofibrate 49562-28-9 For High Good And

loco cholesterol
(pharma)
160 Granisetron HCl 107007-99-8 For Cancer (pharma)
161 Gefitinib 184475-35-2 For Lung Cancer

(Pharma)
162 Gabapentin 60142-96-3 For Neurontin

(Pharma)

12
ANNEXURE II
163 ILoperidone 133454-47-4 For Proton Pump

(Pharma)
164 Irbesartan 138402-11-6 For Hypertension

(Pharma)
165 Itopride Hydrochloride 122892-31-3 For Dyspepsia

(Pharma)
166 Lapatinib 388082-78-8 For Cancer (Pharma)
167 Lurasidone Hydrochloride & its 367514-88-3 For Schizophrenia

intermediate (Pharma)
168 Losartan Potassium 124750-99-8 For Hypertension

(Pharma)
169 Mem Chloride 3970-21-6 For API

(Antibiotics)
170 Minodronic Acid 155648-60-5 For osteoporosis

(Pharma)
171 Moclobemide 71320-77-9 For Depression &

Anxiety (Pharma)
172 Modafinil 68693-11-8 For Sleep apnea &

narcolepsy (Pharma)
173 Metoprolol Tartrate 37350-58-6 For Hypertension

(Pharma)
174 Nisoldipine 63675-72-9 For Hypertension

(Pharma)
175 Omeprazole 73590-58-6 For Antacids and

Peptic Ulcer
(Pharma)
176 O Des Venlafexine 93413-62-8 For Major Depression

Disorder (Pharma)
177 Olmesartan 144689-63-4 For Hypertension

(Pharma)
178 Pitavastatin 147511-69-1 For High & Low

Cholesterol (Pharma)

13
ANNEXURE II
179 Piperonylic Acid 94-53-1 For Piperonal (API)
180 PramipexoleDihydrochloride 191217-81-9 For Renal Liver

Monohydrate (Pharma)
181 Prasugrel Hydrochloride 389574-19-0 For Heart Disease

(Pharma)
182 Paroxetine hcl 61869-08-7 For Depression

(Pharma)
183 Pinaverium Bromide 53251-94-8 For Irritable Bowel

Syndromes (Pharma)
184 Pioglitazone HCl 112529-15-4 For Diabetes

(Pharma)
185 QuetiapineFumarate 111974-72-2 For Schizophrenia

(Pharma)
186 Rabeprazole Sodium 117976-90-6 For Gastroesophageal

Reflux Disease
(Pharma)
187 Rivaroxaban 117976-90-6 For Atrial fibrillation

(Pharma)
188 Ropinirole Hydrochloride 91374-20-8 For Restless Legs

Syndrome (Pharma)
189 Resperidone 106266-06-2 For Schizophrenia

(Pharma)
190 Sertraline Hydrochloride 79559-97-0 For Depression

(Pharma)
191 Solifenacin Succinate 242478-38-2 For Urination &

incontinentia
(Pharma)
192 Tadalafil 171596-29-5 For Erectile Dys

Function (Pharma)
193 Ticagrelor 274693-27-5 For Angioplasty

(Pharma)
194 Topiramate 97240-79-4 For Seizures

14
ANNEXURE II
(Pharma)
195 Vilazodone Hydrochloride 163521-08-2 For (Pharma)
196 Valsartan 137862-53-4 For Hypertension

(Pharma)
197 Vortioxetine Hydrbromide 960203-27-4 For Depression

(Pharma)
198 Vemurafinib 1029872-54-5 For Melonoma

(Pharma)
199 Warfarin Sodium clatharte 67430-45-9 For AntiCoagulant

(Pharma)
200 Ziprasidone HCl 138982-67-9 For Schizophrenia

(Pharma)
201 Vildagliptin 274901-16-5 For Diabetes

(Pharma)
202 Memantine HCL 41100-52-1 For Alzeheimer

(Pharma)
203 Linezolid 165800-03-3 For Infections

(Pharma)
204 Ramelteon 96597-26-9 For Insomnia

(Pharma)
205 Timolol maleate 26839-75-8 For Antibiotic

(Pharma)
206 Salmeterol Xinafoate 94749-08-3 For Adrenergic

(Pharma)
207 Ezetimibe 163222-33-1 For Primary

Hypercholesterolemia
(Pharma)
208 Ritonavir 155213-67-5 For HIV Protease

Inhibitors (Pharma)
209 Glimepiride 93479-97-1 For Diabetes

(Pharma)
GROUP- 6 R&D PRODUCTS

15
ANNEXURE II
Various New Product developed -- 5 --

by In-House R & D with similar
chemistry for production 1 to 209.
TOTAL PRODUCTION -- 180

CAPACITY

16
ANNEXURE III
LIST OF DIRECTORS
Sr.
Name of the Partner Address Contact No.
No.
1. Mr. Mafatlal Maganlal “Tejas”2, Snehdeep Society, Nr +912646250224

Patel GNFC, Township, Bholav,
(CMD) BHARUCH-392015
2. Mr. Vital Mafatlal Patel “Tejas”2, Snehdeep Society, Nr +912646250224
(MD & CEO) GNFC, Township, Bholav,
BHARUCH-392015
3. Mrs. Savitaben Mafatlal “Tejas”2, Snehdeep Society, Nr +912646250224
Patel (Director) GNFC, Township, Bholav,
BHARUCH-392015
4. Mrs. Neelam Vital Patel “Tejas”2, Snehdeep Society, Nr +912646250224
(Director) GNFC, Township, Bholav,
BHARUCH-392015
5. Miss Tejalben Mafatlal “Tejas”2, Snehdeep Society, Nr +912646250224
Patel (Director) GNFC, Township, Bholav,
BHARUCH-392015

17
PROPOSED FACTORY BUILDING PLAN
TOP 10% OF THE PITS / TRENCH N ON SUB DIVISION OF PLOT NO -25 / 8
WILL BE EMPTY AND A SPLASH
IS TO BE PROVIDED IN THIS PORTION
AT G.I.D.C. ESTATE JHAGADIYA
PLOT AREA FOR :- M/S VIHITA CHEM PVT. LTD
COURSE SAND AS UPPER SR NO
PLOT AREA 9570.62 SQ.MT.
MIDDLE AS TOP LAYER TO
1 SECURITY ROOM 57.26 Sqm
20% OF DEPTH.
2 ADMIN AND QC 260.00 sqm
GRAVEL / GRITE LAYER COLOUR CODE 3 GEB YARD 25.05 sqm
TO 20% OF DEPTH. PLOT BOUNDARY 4 PRODUCTION BLOCK 1 600 sqm
G.L. G.L.
PROSED WORK LINE 5 PRODUCTION BLOCK 2 600 sqm

40 MM STONE AGGREGATE 6 PRODUCTION BLOCK 3 600 sqm
APPROCH
AS BOTTOM LAYER TO
RAIN WATER HARVESTING 7 UTILITY AND MAINTENANCE 360 sqm
50% OF THE DEPTH
GREEN BELT / TREES
* 8
9
10
ETP
OPEN AREA
WARE HOUSE
434.00 sqm
746.48 sqm
520.80 sqm
PIPE FOR PERCOLATING 11 CANTEEN 76.00 sqm
12 GREEN BELT 3184.16 sqm
13 OTHER 1943.67 sqm
FOR PERCOLATING
TYPICAL SECTION FOR
RAIN WATER HARVESTING
PIT WITH PERCOLATING BORE WELL
(3.00 x 3.00 x 2.50 DEPTH) GIDC ROAD LENGTH-14.0M
157.87 MT.
GEB ENTRY
GREEN BELT GREEN BELT GATE
YARD
ADMIN AND QC UTILITY

PRODUCTION PRODUCTION PRODUCTION
GREEN BELT
AND
20X13 BLOCK 1 MAINTENANCE 6M
BLOCK 2 BLOCK 3 WIDE
ROAD
15X24
TH-30.0M
25X24 25X24 25X24
GREEN BELT
AD LENG
SECURITY 6M
GREEN BELT
.
WIDE
59.75 MT
ROOM ROAD
57.26 M2
MT.
GIDC RO
65.00
ENTRY
GATE 8 M WIDE ROAD 8 M WIDE ROAD 8 M WIDE ROAD
GREEN BELT ETP AREA

GREEN BELT
WARE HOUSE
GREEN BELT
GREEN BELT
OPEN AREA
30X17
43X17 25X17
CANTEEN
10X8
GREEN BELT
GREEN BELT
GREEN BELT
150.00 MT.
SITE PLAN GIDC ROAD LENTH-14.0M

DRAWN :- HN PATEL SCALE 1CM.=1MT.
M-9428722329 DATE 26.04.2019

patelhimanshu2013@gmail.com DRG. SIZE A3
18
ANNEXURE V
Sr. Name of the Products Name of the Raw CAS no/CI QTY MT/MONTH
no. Materials no.of Raw MT/MT
Materials
GROUP – 1(SR.NO :-1 TO 3) (70 MT/MONTH)

1. 2,3,4,5 –bis-O-[1-Methyl B-D-Fructopyranose 7660-25-5 0.78 54.6
Ethyl idene] B-D- 7664-93-9 0.422 29.54
Fructopyranose Sulphric acid
67-64-1 0.1 7
Acetone
108-88-03 0.04 2.8
Toluene
2. Di Methyl Formamide Di Dimethyl formamide 68-12-2 46.2
Methyl Acetal 0.66
Dimethyl sulphate 77-78-1 1.14 79.8
sodium methoxide 25% 124-41-4 1.952 136.64

solution
3. 4-Methyl Catechol 452-86-8 0.50 35
Diacetic acid Dimethyl 4-Methyl catechol
ester 1310-73-2 44.8
Sodium Hydroxide 0.64
79-11-8 0.76 53.2
Mono Chloro acetic acid
7647-01-0 2.00 140
Hydrochloric acid
108-88-03 0.06 4.2
Toluene
67-56-1 0.15 10.5
Methanol
0.04 2.8
Sulfuric Acid 7664-93-9
GROUP-2(SR .NO:-4 TO 8) (NOT MORE THAN 40 MT/MONTH)
4. 4-Methyl Catechol Methyl Phenol 106-44-5 1.05 42
Hydro Bromic Acid 10035-10-6 1.74 69.6
Hydrogen Peroxide 7722-84-1 0.75 30
Caustic Soda 1310-73-2 0.65 26
Sulphuric Acid 7664-93-9 0.7 28
Butanol 71-36-3 0.15 6
Methylene dichloride 75-09-2 0.1 4
5. Methylenedioxy phenol 44.4

Zinc Chloride 7646-85-7
1.11

19
ANNEXURE V
1 40
methylene dioxybenzene 274-09-9
48
Acetic Anhydride 108-24-7
1.2
0.14 5.6
Methylene dichloride 75-09-2
1.24 49.6
Formic Acid 64-18-6
0.08 3.2
108-88-3
Toluene fresh
0.56 22.4
7722-84-1
Hydrogen Peroxide
0.6 24
67-56-1
Methanol
1.2 48
Sodium Methoxide 124-41-4
6. 4-Chloro-4’ HYDROXY 17.04
Phenol
BENZOPHENONE 108-95-2 0.426
(Route-1) 0.06 2.4
1,2 Dichloro benzene
95-50-1
0.6 24
Aluminium Chloride
7446-70-0
1.054 42.16
4-Chlore Benzoylchloride
5216-25-1
6 4-CHLORO-4’ 0.43 17.2
Phenol
HYDROXY 108-95-2
BENZOPHENONE 0.05 2
1,2 Dichloro benzene
(Route-2) 95-50-1
0.7 28
Aluminium Chloride
7446-70-0
0.8 32
4-Chlore Benzoyl chloride
5216-25-1
0.05 2
Methanol
67-56-1
7. 2-Bromo Veratryl 91-16-7 20
Veratrol
Bromide 0.5
10035-10-6 0.64 25.6
Hydro Bromicacid
75-09-2 0.1 4
Methyl Di Choride(MDC)
7722-84-1 0.3 12
Hydrogen Peroxide
82115-62-6 4.24
P-Formaldehyde
0.106
108-88-03 0.08 3.2
Toluene
Hydro Bromide in Acetic 10035-10-6 1 40
acid

20
ANNEXURE V
64-19-7 0.5 20
Acetic Acid
8. 7-Ethyl trptophol 2 EthylphenylhyDrazine 19398-06-2 53.28
Hydrochloride 1.332
Dimethyl acetamide 127-19-5 0.6 24
Con Sulfuric Acid 7664-93-9 21.28

0.532
0.532 21.28
2,3-dihydrofuran 1191-99-7
0.1 4
Toluene 108-88-03
GROUP- 3(SR NO:-9 TO 53)(NOT MORE THAN 25 MT/MONTH)
9. Di Methyl Formamide Di Iso propyl alcohol 67-63-0 0.72 18
Iso Propyl Acetal di methyl formamide di 4637-24-5 0.72 18
methyl acetal
10. 4-Methoxy Benzaldehyde 19
4-Methoxy benzaldehyde 123-11-5
dimethyl Acetal 0.76
1.4 35
methanol 67-56-1
15
tri methyleorthoformate 149-73-5
0.6
0.222 5.55
caustic soda flakes 1310-73-2
11. Benzaldehyde dimethyl 19
benzaldehyde 100-52-7
Acetal 0.76
1.4 35
methanol 67-56-1
16.55
tri methyleorthoformate 149-73-5
0.662
0.274 6.85
caustic soda flakes 1310-73-2
12. Dimethyl 127-19-5 16.35
AceamideDimethyAcetal Dimethyl Aceamide 0.654
DIMETHYL SULPHATE 77-78-1 0.948 23.7
Sodium methoxide 124-41-4 1.952 48.8
Methanol 1 25
67-56-1
13. o-benzyl hydroxyl amine 20
Benzyl hydrochloride 100-44-7 0.8
N-Hydroxyphlhalimide 524-38-9 1.03 25.75
Methylene dichloride 75-09-2 3 75
Na2CO3 497-19-8 0.6 15

21
ANNEXURE V
TABA CATALYST 1643-19-2 0.02 0.5
Hydrazine hydrate 7803-57-8 0.38 9.5
50
67-56-1 2
methanol
12.5
7647-01-0 0.5
Hydrochlroic acid
40
108-88-03 1.6
TOLUENE
14. 111-30-8 61.725
Glutaraldehyde(25%)-
Endo-9-methyl-9- 2.469
azabicyclo[3,3,1]nonan Acetonedicarboxylic acid 542-05-2 0.912 22.8
e 3-amine
Methylamine hydrochloride 593-51-1 0.42 10.5
Sodium Acetate 127-09-3 0.36 9
Caustic lye 1310-73-2 0.7 17.5
Hydrochlroic acid 7647-01-0 1 25
Methyl Di Choride(MDC) 75-09-2 3 75
Hydroxyl amine 7803-49-8 0.374 9.35
Potassium Carbonate 584-08-7 0.516 12.9
METHANOL 67-56-1 2 50
Ammonical Methanol 7664-41-7
(10% )- 6 150
Rhodium(5%) 7440-16-6 0.2 5
HYDROGEN 1333-74-0 0.04 1
141-78-6 1 25
Ethyl Acetate
15. 2,3- Dihydrofuran 1307-96-6 2.5
Cobalt Oxide 0.1
Silica 7631-86-9 0.2 5
H2 gas 1333-74-0 0.004 0.1
1,4-Butanediol 110-63-4 1.428 35.7
16. 2-AMINO-4-FLUORO 19
Benzophenone Phtalimide 85-41-6 0.76

22
ANNEXURE V
Aluminum chloride 7446-70-0 0.828 20.7
Fluorobenzene 462-06-6 0.596 14.9
Sodium hypo chloride 7681-52-9 1.15 28.75
17. 2-(2-ETHOXY 90-95-1 55.95

PHENOXY)Ethyl Guaithol 2.238
amine.hcl Ethylene Di Chloride (EDC) 107-06-2 2.4 60
Di methyl formamide 68-12-2 2 50
Potassium pthlamine 1074-82-4 1.926 48.15
Hydrochloric acid 7647-01-0 2.52 63
NaOH 1310-73-2 2.86 71.5
18. 2-(2-ETHOXY 55.95

PHENOXY) ETHYL Guaithol 90-95-1 2.238
AMINE Ethylene Di Chloride (EDC) 0.12 3
107-06-2
TOLUENE 0.1 2.5
108-88-03
Di methyl formamide 0.1 2.5
68-12-2
NaOH 3.888 97.2
1310-73-2
Potassium pthlamine 1.926 48.15
1074-82-4
Hydrochloric acid 2.52 63
7647-01-0
19. N- (4- 873-74-5 18
CYANOPHENYL)- 4-cynoAniline 0.72
glycin Mano chloro acetic acid 79-11-8 0.6 15
Sulfuric acid 7664-93-9 0.29 7.25
Sodium hydroxide 1310-73-2 0.26 6.5
Sodium bicarbonate 144-55-8 0.5 12.5
20. 1-(2,'5' DIMETHOXY bromo methyl-2,5- 1204-21-3
PHENYL amino DIMETHOXY PHENYL 40

ethanol) KETON 1.6
100-97-7+
HEXAMINE+ WATER 2.4 60
7732-18-5

23
ANNEXURE V
THF 2 50
109-99-9
Methanol 67-56-1 2 50
75-09-2 50
MDC 2
16940-66-2
NabH4 0.234 5.85
21 Guanidine hydrochloride 506-93-4 40

. Guanidine nitrate 1.6
NH4HCO3 1066-33-7 1.036 25.9
3 75
HCL 7647-01-0
22. Guamidine Nitrate 57-13-6 13.75
Urea 0.55
NH4NO3 6484-52-2 0.72 18
112926-00- 1 25
SILICA 8
23. Guanidine thiocyante 506-93-4 28
Guanidine nitrate 1.12
NH4SCN 1762-95-4 0.7 17.5
124-41-4 50
SMO (25) 2
NaoH 1310-73-2 0.4 10
24. O-BENZYL 100-44-7 20

HYDROXYL AMINE Benzyl hydrochloride 0.8
N-hydroxyphthalimide 524-38-9 1.03 25.75
MDC 75-09-2 3 75
Na2co3 0.6 15
497-19-8
TABA CATALYST 0.02 0.5
1643-19-2
Hydrazine hydrate 0.38 9.5
7803-57-8
2.5
Methanol
67-56-1 0.1
25. Syringaldazine 134-96-3 28
syringaldehyde 1.12
Hydrazine hydrate 7803-57-8 0.252 6.3
Methanol 67-56-1 0.1 2.5

24
ANNEXURE V
DMF 68-12-2 0.04 1
26. 3amino-2- 850261-36-8 14.9

thiophenecarboxylic acid 2-chloroacryonitrile 0.596
methyl thioglycolate 2365-48-2 0.726 18.15
Toluene 108-88-03 0.04 1
25 % SMO 124-41-4 0.50 12.5
27. ETHYL 2-(3-CYANO)- 161798-01-

4-isobutoxyphenyl)-T- ethyl-2-(3-formy-4- 2 26.15
oxo-N,B- hydroxyphenyl) 1.046
diphenylbenzenebutana 5470-11-1
mide
Hydroxy amine HCl 0.796 19.9
Sodium format 141-53-7 1.296 32.4
Formic acid 54-18-6 1.026 25.65
K2CO3 584-08-7 0.4 10
1
DMF 68-12-2 0.04
isobutyl bromide 0.49 12.25
78-77-3
28. SULFMERAZINE 2-amino-4-methyl 0.47
pyrimidine 11.75
108-52-1
25
pyridine 110-86-1 1
N-Acetyl sulfanilyl chloride 121-60-8 1.004 25.1
NaoH 1310-73-2 0.4 10
HCL 7647-01-0 1 25
29. 2-AMINO-4- 124-41-4 0.644 16.1

METHYLPYRIMIDINE Sodium methoxide
ACETONE 67-64-1 2.5
0.1
Ethyl format 109-94-4 0.754 18.85
506-93-4 1.244 31.1

Guanidine nitrate
108-88-03 0.04 1
Toluene
30. methyl-2-amino-3- 94-53-1 25.85
nitrobenzoa Piperonylic acid 1.034

25
ANNEXURE V
CON H2SO4 7664-93-9 0.1 2.5
METHANOL 67-56-1 0.1 2.5
31 Guanidine carbonate 506-93-4 40

Guanidine nitrate 1.6
NH4HCO3 1066-33-7 1.036 25.9
32. N-HYDROXY 85-44-9 25

PHTHALIMIDE Phthalic anhydride 1
hydroxylamine HCL 5470-11-1 0.468 11.7
IPA 67-63-0 0.1 2.5
TEA 121-44-8 0.1 2.5
33. Alpha-Bromo-2-chloro 2856-63-5 25

2-Chlorophenyl)Acetonitrile
phenyl acetic acid methyl 1
aster NaOH 1310-73-2 1.144 28.6
MDC 75-09-2 0.1 2.5
Toluene 0.2 5
108-88-03
NBS 0.672 16.8
128-08-5
67-56-1 2.5
Methanol
0.1
Chloro benzene 0.1 2.5
108-90-7
50% H2SO4 3 75
7664-93-9
34. 4-METHOXY-3-NITRO 128-08-5 22.5
BENZYL SULFONYL NBS 0.9
ACETIC ACID 3-Nitro-4-Methoxy Toluene 119-10-8 0.76 19
Chloro Benzene fresh 108-90-7 0.12 3
Benzoyl peroxide 94-36-0 0.01 0.25
Thioglycolic acid 68-11-1 0.38 9.5
67-56-1 0.13 3.25

Methanol
7722-84-1 1.26 31.5
Hydrogen paroxide

26
ANNEXURE V
Acetic acid 64-19-7 0.1 2.5
35. 3,4-DIHYDROXY Veratric Acid 93-07-2 31.25

BENZOIC ACID 1.25
5 125
Hydrogen Bromide (48 %) 10035-10-6
1.25 31.25
Acetic acid 64-19-7
36. 3,4- Dihydroxy Benzoic 93-07-2 31.25
Acid Methyl ester VERATRIC ACID 1.25
H2SO4 7664-93-9 1.292 32.3
NaOH 1310-73-2 1.054 26.35
METAHNOL 67-56-1 0.04 1
37. Piperonylic Methyl Ester 67-56-1 2.5

METHANOL 0.1
PIPERONYLIC ACID 94-53-1 1 25
H2SO4 7664-93-9 0.1 2.5
38. Ethyl 3-[(pyridin-2-yl)- 140-88-5 12.5

amino]-propanoate ETHYL ACETATE 0.5
2-AMINO PURIDINE 504-29-0 0.52 13
ACETIC ACID 64-19-7 0.2 5
CYCLOHEXANE 110-82-7 0.6 15
39. 3-nitro-4-methylamino 3-NITRO-4- 96-99-1

benzoic acid METTHYLAMINO 28.7
BENZOIC ACID 1.148
METHYL AMINE 78-89-5 0.46 11.5
HCL 7647-01-0 1 25
40. HYDROQUININE 123-31-9 22.15

dimethyl ester HYDROQUINONE 0.886
TOLUENE 108-88-03 0.04 1
DIMETHYL SULFIDE 77-78-1 1.616 40.4
NaOH 1310-73-2 1.04 26
41. MALONIC ACID 108-59-8 23.55

METHYL ESTER DIMETHYL MALONATE 0.942
potassium salt KOH 1310-58-3 0.338 8.45

27
ANNEXURE V
METHANOL 67-56-1 0.04 1
42. (1R,2R)-1,2 1,2-cyclohexane 2305-32-0 58.3

CYCLOHEXANE dicarboxylic acid 2.332
DICARBOXYLIC ACID METHANOL 67-56-1 0.1 2.5
ALPHA METHYL 3886-69-9

BENZYL AMINE 1.57 39.25
ETHYL ACETATE 141-78-6 0.1 2.5
CON HCL 7647-01-0 1.56 39
1-METHYLINDAZOLE- 100-52-7 28.8

43. 3-CARBOXYLIC ACID Benzaldehyde 1.152
phenyl hydrazine 100-63-0 1.172 29.3
MDC 75-09-2 4.4 110
Oxalyl chloride 79-37-8 1.344 33.6
ALCL3 7446-70-3 1.42 35.5
ACETIC ACID 64-19-7 2 50
CONC HCL 7647-01-0 2 50
N,N-dimethyl Acetamide 127-29-5 1 25
ACETONE 67-64-1 0.1 2.5
77-78-1 0.672 16.8

DMS
NaOH 1310-73-2 0.868 21.7
ISOVANILIC ACID 621-59-0 37.5

44. Isovanillin 1.5
Formic acid 64-18-6 1.026 25.65
Hydroxy amine HCL 5470-11-1 0.796 19.9
sodium. formate 141-53-7 1.296 32.4
NaOH 1310-73-2 0.4 10
H2SO4 7664-93-9 0.612 15.3
2-METHYL-3-OXO- 105-45-3 27.85

45. Pentanoate Methyl Aceto acetate 1.114

28
ANNEXURE V
MDC 75-09-2 0.4 10
Propinoyl chloride 79-03-8 0.884 22.1
Ca(OH)2 1305-62-0 0.846 21.15
46. 2-(2 ETHOXY 90-95-1 55.95

PHENOXY)mesylate Guaithol 2.238
EDC 107-06-2 0.5 12.5
108-88-03
Toluene 0.1 2.5
NaOH 1310-73-2 2 50
DMF 68-12-2 1.988 49.7
1074-82-4 48.15
Potassium pthlamine 1.926
Hcl 7647-01-0 2.52 63
Methane sulfonic acid 75-75-2 1.558 38.95
47 3-(((2-methoxy-2- methyl-3-(chlorosulfonyl)-2- 59337-92-7 25

oxoethyl)amino)- thiophene carboxylate 1
sulfonyl)-2- glycine methyl ester 31954-27-5 0.63 15.75
thiopenecarboxylic acid
methyl ester Methanol 67-56-1 0.1 2.5
48. methyl-6- 104-90-5 22.5

methyinicotinate 5-Ethyl-2-Methyl Pyridine 0.9
H2SO4 7664-93-9 0.8 20
HNO3 7697-37-2 0.8 20
METHANOL 67-56-1 0.1 2.5
MDC 75-09-2 0.1 2.5
49. 4-[(4-Methyl-1- 17201-43-3 21

piperazinyl)-methyl]- 4-cyano benzyl bromide 0.84
benzoic acid N-methyl piperazine 109-01-3 1.18 29.5
chloroform 67-66-3 2 50
con HCL 7647-01-0 3.3 82.5

29
ANNEXURE V
50. 2-(((2'-cyano- 114772-54-

(1,1'biphenyl)-4-yl)- 4-bromomethyl-2- 2 18.85
methyl)amino)-3-niro cyanobiphenyl 0.754
benzoic acid) methyl-2-amino-3-nitro 57113-91-4
benzoate 0.584 14.6
DMF 68-12-2 1 25
K2CO3 584-08-7 0.2 5
51. NDLIC ANHYDRIDE 77-73-6 11.2

(endo- cis- bicyclo- cyclopentadine 0.448
(2.2.1)-5-heptane-2,3- Ethyl acetate 141-78-6 0.1 2.5
dicarboxylic acid)
maleic anhydride 108-31-6 0.664 16.6
52. 4- METHOXY-3-(3- 645-08-9 18.85

METHOXYPROPOXY) Isovanilic acid 0.754
BENZOIC ACID 1- chloro-3-methoxy 36215-07-3
propane 0.498 12.45
DMF 68-12-2 0.06 1.5
K2CO3 548-08-7 0.488 12.2
53. 3- cyclopropyl-3-oxo 105-45-3 22.5

Propionic Acid Methyl Methyl Acetoacetate 0.9
Ester cyclopropanecarbonyl 4023-34-1
chloride 0.812 20.3
MDC 75-09-2 0.1 2.5
Ca(OH)2 1305-62-0 0.846 21.15
Group-4(sr no:-55 to124) not more than 25 MT/MONTH

54 4-HYDROXY BENZYL 4-hydroxy Benzaldehyde 123-08-0 1.016 25.4
ALCOHOL PD/C Catalyst 0.004 0.1
7440-05-3
Methanol 0.084 2.1
67-56-1
Hydrogen 0.016 0.4
1333-74-0
55 2,4,6 TRI 68-12-2 21
METHOXYBENZALDE DMF 0.84
HYDE POCl3 10025-87-3 0.8 20
Methanol fresh 67-56-1 0.1 2.5

30
ANNEXURE V
1,3,5 Tri methoxy Benzene 621-23-8 0.9 22.5
Sodium carbonate 497-19-8 1.2 30
56. 4-ISOPROPYL 99-88-7 27.5

CATECHOL P-cumidine 1.1
Sodium nitrite 0.56 14
7632-00-0
Methelyne dichloride 75-09-2 0.1 2.5
0020 10035-
10-6 31
Hydrogen bromide 1.24
Hydrogen paroxide 7722-84-1 0.5 12.5
7758-98-7 0.1 2.5

Copper sulfate
Sulfuric acid 7664-93-9 38
1.52
N-Butanol 71-36-3 0.06 1.5
7440-50-8 0.02 0.5

COPPER
57. 3-methoxy phenol 108-46-3 0.95 23.75
Resorcinol
77-78-1 1.1 27.5
Dimethyl sulphate
7664-93-9 0.8 20
50 % H2SO4
108-88-3 0.1 2.5
Toluene
497-19-8 1.1 27.5
Na2co3
1310-73-2 1.5 37.5
50%NaOH Solution
58. VERATRYL ALCOHOL 121-33-5 23.5
Vanillin 0.94
Dimethyl sulphate 77-78-1 1.324 33.1
Toluene 108-88-3 0.26 6.5
497-19-8 33.1
Sodium carbonate 1.324
67-56-1 0.1 2.5

METHANOL

31
ANNEXURE V
75-09-2 0.1 2.5

Methelyen dichloride
NaBH4 16940-66-2 0.12 3
59. 3,4-Dihydroxy 121-33-5

Benzaldehyde
31.25
VANILLIN 1.25
ALCL3 7446-70-0 1.092 27.3
PYRIDINE 110-86-1 0.8 20
MDC 75-09-2 0.1 2.5
HCL 7647-01-0 0.76 19
60 4-PROPYL CATECHOL 645-56-7 25

4-Propyl phenol 1
Methelyen dichloride fresh 75-09-2 0.1 2.5
10035-10-6 31
HBr 1.24
Hydrogen paroxide 7722-84-1 0.5 12.5
N-Butanol fresh 71-36-3 0.06 1.5
7664-93-9 18
Sulfuric acid 0.72
Copper 7440-50-8 0.02 0.5
61. (3S,4R)-4-(4- 459-57-4 31

4-Fluoro Benzaldehyde 1.24
Fluorophenyl)-3-
Pyridine 110-86-1 0.05 1.25
hydroxymethyl-1-
methylpiperidine Malonic acid 141-82-2 1.4 35
7719-09-7 0.05 1.25

Thionyl chloride
DMF 68-12-2 0.02 0.5
105-53-3 35
Diethyl malonate 1.4
Potassium t butoxide 865-47-4 1.032 25.8
NaBH4 16940-66-2 0.7 17.5

32
ANNEXURE V
BF3 etherate fresh 109-63-7 0.1 2.5
133-37-9 1 25
Tartaric acid
Iso propyl alcohol 67-63-0 0.1 2.5
Concentric hydrochloric acid 7647-01-0 1 25
62. 3-METHOXY 93-55-0 20.4

PROPIOPHENONE Propiophenone 0.816
EDC 107-06-2 0.1 2.5
Aluminium chloride 7446-70-0 1.22

30.5
68-12-2 2.5
DMF 0.1
108-88-3 0.1 2.5
Toluene
Bromine 7726-95-6 24.35
0.974
Dil hydrochloric acid 7647-01-0 2 50
25% SMO 124-41-4 1.5 37.5
CUCl 7758-89-6 0.1 2.5
4-HYDROXY 106-44-5 22.15

63. BENZALADEHYDE P-CRESOL 0.886
METHANOL 67-56-1 0.1 2.5
NaOH 1310-73-2 0.656 16.4
COBALT ACETATE 71-48-7 0.1 2.5
H2SO4 7664-93-9 0.802 20.05
Piperonyl Alcohol 67-56-1 5

64. METHANOL 0.2
PIPERONYL ACID 94-53-1 1.248 31.2
H2SO4 7664-93-9 0.1 2.5
NaBH4 16940-66-2 0.22 5.5
65. 3,4-dimethoxy phenol 91-16-7 25

VERATOL 1
MDC 75-09-2 2 50

33
ANNEXURE V
AlCl3 7446-70-0 0.96 24
CH3COl 75-36-5 0.59 14.75
PD/C CATALYST 0.2 5
HYDROGEN PEROXIDE 7722-84-1 0.56 14
TOLUENE 108-88-03 0.56 14
64-18-6 1.24 31
FORMIC ACID
SODIUM METHOXIDE 124-41-4 1.2 30
METHANOL 67-56-1 0.6 15
66. 4-METHYL 3-bromo-4-hydroxy- 60710-39-6 1.508

GUAIACOL 37.7
toluene
DMF 68-12-2 0.04 1
CUCL 7758-89-6 0.2 5
25 %(SMO) 124-21-4 1.114 27.85
67. ISOVANILLYL 16940-66-2 7

ALCOHOL NaBH4 0.28
METHANOL 67-56-1 0.1 2.5
ISOVANILLIN 621-59-0 1.1 27.5
MDC 75-09-2 0.1 2.5
68 3-Methoxy benzyl 3-BROMO 3132-99-8 44

alcohol BENZALDEHYDE 1.76
TOLUENE 108-88-03 0.04 1
MONO ETHYLENE 107-21-1

GYLCOL 0.588 14.7
DMF 68-12-2 0.04 1
7758-89-6 0.1 2.5

CUCL
Toluene 108-88-03 0.04 1
DILL. HCL 7647-01-0 2 50

34
ANNEXURE V
25% SMO 124-41-4 1.7 42.5
METHANOL 67-56-1 0.1 2.5
NaBH4 16940-66-2 0.44 11
2,5-dimethoxy 90-02-8 20.6

69. Benzaldehyde Salicylaldehyde 0.824
HBR 10035-10-6 1.124 28.1
H2O2 7722-84-1 0.7 17.5
DMS 75-18-3 0.516 12.9
NaoH 1310-73-2 0.66 16.5
Toluene 108-88-03 0.08 2
25 % SMO 124-41-4 1.5 37.5
68-12-2 0.04 1
DMF
CUCl 7758-89-6 0.1 2.5
Dil HCL 7647-01-0 2 50
Ethylene glycol 107-21-1 0.444 11.1
70. 5- NITROVANILLIN 7697-37-2 7

CON.HNO3 0.28
METHANOL 67-56-1 0.1 2.5
VANLLIN 121-33-5 0.844 21.1
71. 4-Hydroxy Anisole 100-66-3 1.072 26.8

ANISOLE
MDC 75-09-2 0.28 7
H2O2 7722-84-1 0.824 20.6
Hbr 10035-10-6 1.826 45.65
HCL 7647-01-0 1.4 35
NaOH 1310-73-2 1.026 25.65
N- BUTANOL 71-76-3 0.086 2.15

35
ANNEXURE V
72. Salicylaldehyde 108-95-2 21.5

PHENOL 0.86
mg METHOXIDE 109-88-6 2 50
50-00-0
HCHO 0.21 5.25
ISOVANILLIN 120-14-9 38.5

73. Vetraldehyde 1.54
H2SO4 7664-93-9 280.75
11.23
MDC 75-09-2 34.5
1.38
NaoH sol wash 1310-73-2 42.5
1.7
74 Watermelon ketone 452-86-8 19.4
4-METHYL CATECHOL 0.776
ACETONE 67-64-1 0.55 13.75
SODA ASH 497-19-8 0.662 16.55
1,3 Dichloro acetone 534-07-6; 0.794 19.85
TOLUENE 108-33-03 0.05 1.25
Diisopropyl ether 108-20-3 0.1 2.5
75. (1R,2R)-1,2- 1R,2R)-1,2-Cyclohexane di 46022-05-3 20

cyclohexanedimemethano carboxylic Acid 0.8
l THF 109-99-9 0.04 1
MDC 75-09-2 0.1 2.5
NaoH 1310-73-2 0.026 0.65
16940-66-2 1.75
NaBH4 0.07
BF3 Etharate 109-63-7 0.36 9
76. 3',4'-( Methylenedioxy)- 274-09-9 20.7

Acetophenone Methylene dioxybenzene 0.828
ZnCL2 7646-85-7 0.922 23.05
MDC 75-09-2 0.1 2.5
Acetic acid 108-24-7 0.244 6.1
Methanol 67-56-1 0.1 2.5

36
ANNEXURE V
3,4-DIHYDROXY-5- 121-33-5 24.15

77. NITRO- VANILLIN 0.966
BENZALDEHYDE Methanol 67-56-1 0.1 2.5
Con HNO3 7697-37-2 0.42 10.5
Hbr(48 %) 10035-10-6 4 100
Acetic acid 64-19-7 0.04 1
78 2,4-di 98-88-4 18.15

HydroxyBenzophenone Benzoyl chloride 0.726
Resorcinol 108-46-3 0.572 14.3
1,2 di chloro benzene 95-50-1 0.04 1
AlCL3 7446-70-3 0.716 17.9
Methanol 67-56-1 0.1 2.5
79. 2-hydroxy benzyl Salicylaldehyde 90-02-8 1.1

27.5
alcohol
Methanol 67-56-1 2.5
0.1
MDC 75-09-2 0.1 2.5
NaBH4 16940-66-2 0.28 7
80. N-BENZYL-4- 100-44-7 17.3

PIPERIDINECARBOXA benzyl chloride 0.692
LDEHYDE PIPERDINE -4- 50675-20-2
carboxyaldehyde 0.73 18.25
t- butanol 75-65-0 0.06 1.5
Toluene 108-88-03 0.04 1
NaoH 1310-73-2 0.2 5
81. 5,6- DIMETHOXY 3,4- dimethoxy 120-14-9 28.7

INDANONE Benzaldehyde 1.148
Methanol 67-56-1 0.2 5
malonic acid 141-82-2 0.64 16
7440-05-3 0.2 5
Pd/c

37
ANNEXURE V
H3PO4 7664-38-2 1 25
Hydrogen 1333-74-0 0.02 0.5
82 3-(1-Plperazinyl)-1,2- 119-80-2 45
benzisothiazole/HCL 2, 2'-Dithiosalicylic acid 1.8
Sulfuric acid 7664-93-9 0.06 1.5
Toluene fresh 108-88-03 0.19 4.75
124-41-4 9.1
NaOCH3 0.364
Acetamide 60-35-3 0.33 8.25
10025-87- 3 20.25
POCl3 0.81
Piperazine 110-85-0 0.44 11
83. 5-CHLOROETHYL-6- 2-5-DI Chloro Nitro 89-61-2 26.05

CHLORO-2-OXINDOLE Benzene 1.042
DMSO fresh 67-68-5 0.1 2.5
Methelene dichloride fresh 95-09-2 0.1 2.5
26.05
Di methyl sulphoxide 108-59-8
1.042
K2CO3 584-08-7 0.75 18.75
Acetic acid fresh 64-19-7 0.1 2.5
Iron 7439-89-6 0.306 7.65
CAC 79-04-9 0.6 15
Zinc chloride 7646-85-7 0.746 18.65
Tri ethyl silane 617-86-7 0.63 15.75
84. 4-4-METHYL-1- 17201-43-3 21

PIPERAZINYL)- 4-cyano benzyl bromide 0.84

38
ANNEXURE V
methyl]-benzoylchloride Methelyen dichloride fresh 75-09-2 0.1 2.5

dihydrochloride
DMF fresh 68-12-2 0.1 2.5
N-methyl piperazine 109-01-3 1.18 29.5
Thionyl chloride fresh 7719-09-7 0.1 2.5
chloroforom fresh 67-66-3 0.1 2.5
con HCl 7647-01-0 4 100
85. 1-(Benzo (d)(1,3)dioxal- 67-56-1 2.5

5-yl) )ethanol methanol 0.1
3,4(methylenedioxy) 3162-29-6
acetophenone 1.092 27.3
NaBH4 16940-66-2 0.26 6.5
86. 2-BROMO 2,5 123-31-9 17.5

DIMETHOXY Hydroqinone 0.7
ACETOPHENONE Methylene chloride 70110-03-1 0.1 2.5
Caustic soda 1310-73-2 0.48 12
Zinc chloride 7646-85-7 0.6 15
Acetic anhydride 108-24-7 0.65 16.25
Hydrogen paroxide 7722-84-1 0.24 6
Hydrogen bromide 10035-10-6 0.578 14.45
(1R,2R)-1,2- 1R,2R)-1,2- 46022-05-3

87. BIS(METHANESULFO
NYLOXYMETHYL)CY
Cyclohexane di 15
CLOHEXANE carboxylic Acid 0.6
THF fresh 109-99-9 0.04 1
Methelyene dichloride fresh 0.2 5

75-09-2
Methane sulfonylchloride 124-63-0 0.43 10.75
Tri ethyl Amine 121-44-8 0.4 10
TERT BUTYL(4- 100-61-8 10.65

88. bromophenyl)methylcarb N-methyl aniline 0.426

39
ANNEXURE V
amate DMF 68-12-2 0.1 2.5
MDC 75-09-2 0.2 5
NaOH 1310-73-2 0.29 7.25
NBS 128-08-5 0.336 8.4
BOC 24424-99-5 0.784 19.6
89. 2-Cyclopropyl-4- 2-amino-4-fluoro 3800-06-4 19.3

4fluorophenyl)quinolone- Benzophenone 0.772
3-yl menthanol 3-cyclopropyl-3-oxo 32249-35-7
propionic acid methyl ester 0.75 18.75
Methanol 67-56-1 0.3 7.5
con H2SO4 7664-93-9 0.04 1
TOLUENE 108-88-3 1 25
DIBAL H (25% SOL in 1191-15-7

toluene) 0.1 2.5
HCL 7647-01-0 2 50
Na2co3 497-19-8 50 1250
10 %NaHCO3 144-55-8 4 100
90. 2-BROMO-3’-CHLORO 936-59-4 19

-PROPIOPHENONE 3-chloro Propiophenone 0.76
MDC 75-09-2 0.1 2.5
BROMINE 7726-95-6 0.714 17.85
92. 3- bromo- 4-hydroxy 60710-39-6 26

Benzaldehyde 3- bromo- 4-hydroxy toluene 1.04
METHANOL 67-56-1 0.1 2.5
NaOH 1310-73-2 0.444 11.1
COBALT ACETATE 71-48-7 0.2 5
H2SO4 7664-93-9 0.546 13.65
Water 7732-18-5 0.1 2.5

40
ANNEXURE V
92. 3,4-(methylenedioxy) METHYLENE 274-09-9 16.9

bromo benzene DIOXYBENZENE 0.676
HBR 10035-10-6 0.92 23
H2O2 7722-84-1 0.4 10
93. 3-Methoxy Benzyl 3-METHOXY BENZYL 6971-51-3 25

chloride ALCOHOL 1
SOCL2 7719-09-7 0.862 21.55
DMF 68-12-2 0.04 1
94. 4- CHLORO 3-bromo-4-hydroxy- 13659-24-0

37
GUAIACOl benzene 1.48
DMF 68-12-2 0.04 1
NaOCH3 124-41-4 1.114 27.85
CUCL 7758-89-6 0.2 5
95. 4-CHLORO 16766-30-6 25

VERATROLE 4-chloro-guaiacol 1
toluene 108-88-03 0.04 1
NaOH 1310-73-2 0.506 12.65
DMS 77-78-1 0.796 19.9
96. 2-bromo-4- Chloro 106-48-9

17.2
Phenol
P-CHLORO PHENOL 0.688
HBR 10035-10-6 0.96 24
H2O2 7722-84-1 0.3 7.5
97. 4-bromo anisole 100-66-3 16.05

ANISOLE 0.642
Hbr 10035-10-6 1.09 27.25
H2O2 7722-84-1 0.49 12.25
98. 4-bromoPhenetole 108-95-2 0.592 14.8

PHENOL
DES 64-67-5 0.766 19.15
NaOH 1310-73-2 0.388 9.7
TOLUENE 108-88-03 0.04 1

41
ANNEXURE V
Hbr 10035-10-6 1.09 27.25
H2O2 1333-74-0 0.49 12.25
99. Endo-9-methyl-9- 111-30-8

azabicyclo[3,3,1]nonane Glutaraldehyde(25%) 2.496 62.4
3-amine 2 HCL
Acetonedicarboxylic acid 542-05-2 0.912 22.8
MDC 75-09-2 0.1 2.5
Methylamine hydrochloride 593-51-1 0.42 10.5
SODIUM ACETATE 127-09-3 0.36 9
CAUSTIC LYE 1310-73-2 0.7 17.5
HCL 7647-01-0 1 25
9-Methyl-9-
azabicyclo[3,3,1]nonan-3-
One 0.824 20.6
Hydroxyl amine 7803-49-8 0.374 9.35
Methanol 67-56-1 0.1 2.5
POTTASIUM 584-08-7
CARBONATE 0.516 12.9
IPA 67-63-0 2 50
ETHYL ACETATE 141-78-6 1 25
AMMONICAL 7664-41-7
METHANOL 6 150
Rhodium(5%) 7440-16-6 0.2 5
Hydrogen pressure 1333-74-0 0.04 1
100. 2-BROMO-4-CYANO 3-bromo-4-hydroxy- 2973-78-6

PHENOL benzaldehyde 1.128 28.2
Formic acid 64-18-6 1.026 25.65
Hydroxy amine HCL 5470-11-1 0.796 19.9

42
ANNEXURE V
sodium. formate 141-53-7 1.296 32.4
101. 2-Chloro-4,6-dimethoxy- METHANOL 67-56-1 0.54 13.5

[1,3,5]-triazine
NaHCO3 144-55-8 1.374 34.35
Cyanuric chloride 108-77-0 1.71 42.75
MDC 75-09-2 0.198 4.95
TOLUENE 108-88-03 0.11 2.75
102. BICYCLO[2.2.1] hep- Bicyclo(2,2,1)hept-5-ene- 826-62-0

tane-2,3-exo- 2,3-Dicarboxylic Anhydride 1.3 32.5
dicarboximide
ETHYL ACETATE 141-78-6 0.2 5
PD/c 7440-05-3 0.2 5
THF 109-99-9 0.2 5
NH3 soln 7664-41-7

(25%)(NH3+H2O) 2.4 60
103. 4-BROMO PHENOL PHENOL 108-95-2 0.57 14.25
BROMINE 7726-95-6 0.96 24
ETHYL ACETATE 141-78--6 0.14 3.5
104 2-(2-ethoxyphenoxy)- Guaithol 90-95-1 0.58 14.5

ethyl bromide
EDB 106-93-4 0.82 20.5
NaOH 1310-73-2 0.2 5
105. ethyl-3[1-(3-amino-4- 96-99-1

(methylamino)-phenyl)- 3-Nitro-4-chloro-benzoic
N-(pyridin-2-yl)- acid 1 25
formamido) propanoate
METHANOL 67-56-1 0.2 5
METHYL AMINE 74-89-5 0.219 5.475
Ethyl-3-(pyridine-2-yl-) - 103041-38-9
amino) propanoate 0.821 20.525
Trimethyl amine 75-50-3 0.65 16.25

43
ANNEXURE V
Pd/c catalyst 7440-05-3 0.13 3.25
hydrogen 1333-74-0 0.13 3.25
ethyl acetate 141-78-6 0.1 2.5
106. ethyl-N-[2-(((4- 96-99-1

Cyanophenyl)-amino)-
methyl)-1-methyl-1H-
benzimidazol-5-yl)- 3-Nitro-4-chloro-benzoic
carbonyl)-N-Pyridin-2-yl- acid 0.73 18.25
B-alanimate
Methanol 67-56-1 0.2 5
Methyl amine 74-89-5 0.16 4
Ethyl-3-(pyridine-2-yl-) 103041-38-
amino propanoate 9 0.6 15
Trimethyl amine 75-50-3 0.48 12
Pd/c catalyst 7440-05-3 0.1 2.5
Hydrogen 1333-74-0 0.1 2.5
Ethyl acetate 141-78-6 0.1 2.5
N-(4-cyanophenyl)-glycine 42288-26-6 0.64 16
toluene 108-88-03 0.04 1
107. 6-CHLORO-OXINDOLE 2,5 Di chloro nitro benzene 89-61-2 1.536 38.4
DMSO 67-68-5 0.1 2.5
di methyl sulphoxide 67-68-5 1.536 38.4
K2CO3 584-08-7 1.104 27.6
Acetic ACID 64-19-7 1.2 30
HCL 7647-01-0 0.6 15
IRON 7439-89-6 0.34 8.5
Methanol 67-56-1 0.1 2.5

44
ANNEXURE V
108. 6-CHLORO-5- 89-61-2

(CHLOROACTYL)-1,3- 2,5 Di chloro nitro benzene 1.042
DIHYDRO-2H- 26.05
INDOLE-2- ONE
DMSO 67-68-5 0.1 2.5
di methyl sulphoxide 67-68-5 1.042 26.05
K2CO3 584-08-7 0.75 18.75
Acetic ACID 64-19-7 0.2 5
HCL 7647-01-0 0.6 15
IRON 7439-89-6 0.306 7.65
Methanol 67-56-1 0.1 2.5
Chloro acetyl chloride 79-04-9 0.6 15
ALCL3 7446-70-0. 0.746 18.65
MDC 75-09-2 0.1 2.5
109. 3,4-(methylenedioxy- 4- methyl catechol 452-86-8 0.896 22.4

Toluene
MDC 75-09-2 0.56 14
NaoH 1310-73-2 0.58 14.5
110. 2-chloro-4,6- Sodium Hypochlorite 7681-52-9

dimethoxybenzaldehyde (NaOCl) 10 250
3,4- Dimethoxy 120-14-9

Benzaldehyde 0.83 20.75
HCL 7647-01-0 1 25
111. 2-chloro-2’,5’-dimethoxy 1,4- Dimethoxy benzene 150-78-7 0.72 18

Acetophenone
ALCL3 7446-70-3 0.72 18
MDC 75-09-2 0.1 2.5

45
ANNEXURE V
112. 4-fluoro-alpha-(2-methyl- 103-82-2

1-oxopropyl)-t-oxo-
N,B,Diphenylbenzenebut phenyl acetic acid 0.37 9.25
anamide
Thionyl chloride 7719-09-7 0.322 8.05
MDC 75-09-2 0.3 7.5
florobenzene 462-06-6 0.26 6.5
Br2 7726-95-6 0.22 5.5
Methyl isobutyl acetate 42558-54-3 0.32 8
Aniline 62-53-3 0.26 6.5
toluene 108-88-03 0.04 1
K2CO3 584-08-7 0.33 8.25
IPA 67-63-0 0.04 1
113. 5-BROMO-6- 274-09-9

BROMOMETHYL-1,3- SML-1 0.5 12.5
BENZODIAZOLE
HBR 10035-10-6 0.64 16
MDC 75-09-2 0.1 2.5
H2O2 7722-84-1 0.3 7.5
HBR IN Acetic ACID 37348-16-6 1 25
FORMALDEHYE 50-00-0 0.106 2.65
Toluene 108-88-03 0.08 2
Acetic ACID 64-19-7 0.5 12.5
114. 6-FLUORO-3-(4- 84163-77-9

Piperidinyl)1,2- 6-fluoro-1,2-benisoxazole 0.57 14.25
benzisoxazole
Piperidine 110-89-4 0.29 7.25
t- butanol 75-65-0 0.06 1.5
Toluene 108-88-03 0.04 1
NaoH 1310-73-2 0.2 5

46
ANNEXURE V
115. 2,4-dimethoxy benzyl 2,4-Dimethoxy Benzaldehyde 613-45-6 1.1 27.5

chloride
METHANOL 67-56-1 0.1 2.5
MDC 75-09-2 0.1 2.5
NaBH4 16940-66-2 0.28 7
SO2CL 585-47-7 0.862 21.55
DMF 68-12-2 0.04 1
116. methyl-4- 4-methyl benzoic acid 99-94-5 0.73 18.25

(Bromomethyl)-benzoate
H2SO4 7664-93-9 0.1 2.5
Methanol 67-56-1 0.5 12.5
MDC 75-09-2 0.1 2.5
Chloro benzene 108-90-7 0.1 2.5
NBS 128-08-5 0.354 8.85
117. 1,2,3,4- tetrahydro-9- 504-02-9

methyl-4H-CARBAZOL- 1,3-Cyclo Hexane dione 0.622 15.55
4-ONE
Phenyl hydrazine 100-63-0 0.6 15
ZNCL2 7646-85-7 0.596 14.9
Methanol 67-56-1 0.1 2.5
ACETIC ACID 64-19-7 1 25
118. 4,5-dimethoxy-2- nitro 3,4 -Dimethoxy toluene 494-99-5 0.844 21.1

toluene
Methanol 67-56-1 0.1 2.5
Con HNO3 7697-37-2 0.264 6.6
119. ALPHA-BROMO- 2856-63-5

ORTHO-CHLORO-
PHENYL ACETIC 2-Chlorophenyl)Acetonitrile 1 25
ACID
Naoh 1310-73-2 1.124 28.1
MDC 75-09-2 0.1 2.5

47
ANNEXURE V
TOLUENE 108-88-03 0.1 2.5
Chloro benzene 108-90-7 0.1 2.5
50 % H2SO4 7664-93-9 2 50
CATALYST 1643-19-2 0.02 0.5
120. 3,4-(Dimethoxy)-6- 3,4-(methylenedioxy) 7145-99-5

methylbenzyl chloride toluene 20.45
0.818
Acetic acid 64-19-7 0.5 12.5
HCHO 50-00-0 0.252 6.3
-- 37.5
Acetic acid in HCL 1.5
TOLUENE 108-88-03 0.04 1
121 ANISOLE Phenol 108-95-2 1 25
Toluene 108-88-3 0.04 1
CH3SO4NA -- 1.424 35.6
122 VERATROL Catechol 120-80-9 1.12 28
Toluene 108-88-03 0.04 1
CH3SO4NA --
2.728 68.2
123 3-methoxy-4-hydroxy- Copper oxide 1317-38-0 1.2 30

benzaldehyde(Vanillin)
Guaiacol 90-05-1 0.952 23.8
Naoh 1310-73-2 1.2 30
50% H2SO4 7664-93-9 6 150
Water 7732-18-5 1.8 45
Methanol 67-56-1 0.1 2.5
Oxygen 7782-44-7 0.1 2.5
124 Ethyl vanillin Glyoxylic acid 298-12-4 1.13 28.25

48
ANNEXURE V
Guiathol 76-05-1 1 25
Naoh 1310-73-2 1.2 30
50% H2SO4 7664-93-9 6 150
Water 7732-18-5 1.8 45
Methanol 67-56-1 0.1 2.5
Copper Oxide 1317-38-0 0.1 2.5
Oxygen 7782-44-7 0.1 2.5
125 3,4-methylenedioxy Glyoxylic acid 298-12-4 1.2 30

Benzaldehyde(Piperonal)
1,2-methylene Dioxy 274-09-9
Benzene 0.952 23.8
Naoh 1310-73-2 1.2 30
50% H2SO4 7664-93-9 6 150
Water 7732-18-5 1.8 45
Methanol 67-56-1 0.1 2.5
Copper oxide 1317-38-0
0.1 2.5
Oxygen 7782-44-7 0.1 2.5
126 1-[3-(benzyloxy)propyl]- 1-[3-(benzyloxy)propyl}-7- 1375180-

5-formaylindoline-7- bromoindoline-5- 28-1
carbonitrite carbaldehyde 1.25 31.25
DMF 68-12-2 0.1 2.5
544-92-3 0.3 7.5

Coppercyanide
Methanol 67-56-1 0.1 2.5
127 Dimethylformamide di- Ethylformimade 68-12-0 0.406 10.15

tert-butyl Acetal
Dimethyl sulfate 68-12-0 0.7 17.5
75-65-0 0.1 2.5

T-Butanol

49
ANNEXURE V
Potassium tert-buoxide 865-47-4 0.64 16
Group -5(sr no:-128-209)(not more than 15 MT/MONTH )

128 AFATINIB (S,E)-N-(4-(3-Chloro-4- 1680184-
DIMALEATE fluorophenylamino)-7- 59-1
(tetrahydrofuran-3-
yloxy)quinazolin-6-yl)-4-
(dimethylamino)but-2-
enamide Afatinib 0.61 9.15
Maleic Acid 110-16-7 0.24 3.6
Methanol 67-56-1 0.18 2.7
129. ARBUTINE 123-31-9 7.5

Monoacetyl hydroquinone 0.5
MDC fresh 75-09-2 0.2 3
BF3-etherate 109-63-7 0.3 4.5
Penta acetyl-B-D-glucose 604-69-3 1.56 23.4
Tri ethyle amine 121-44-8 6.12

0.408
Sodium methoxide 124-41-4 0.02 0.3
130. AGOMELATINE 138113-08-

2-(7-Methoxy-1-naphthyl) 3 13.35
acetonitrile 0.89
Methanol + Ammonia fresh --- 0.1 1.5
Reney Ni 12635-27-7 0.1 1.5
Acetyl chloride 75-36-5 0.29 4.35
131. APIXABAN Ethyl 1-(4-methoxyphenyl)-

7-oxo-6-(4-(2-
oxopiperidine-1-yl)phenyl)-
4,5,6,7 tetrahydro-1H-
pyrazolo[3,4-c]pyridine-3- 16.65
Carboxylate 503614-91-3 1.11
Ethylene glycol fresh 107-21-1 0.1 1.5
NH3 solu 7664-41-7 2.8 42

50
ANNEXURE V
132. ARIPIPRAZOLE 120004-79-

7-(4-Chlorobutoxy)-3,4- 7 12.75
dihydro-2(1H)-quinolinone 0.85
N,N-dimethylformamide 68-12-2
fresh 0.06 0.9
1-(2,3- 119532-26-
dichlorophenyl)piperazine 2
HCl 0.652 9.78
Acetonitrile fresh 75-05-8 0.1 1.5
Iso Propyl Alcohol fresh 67-63-0 0.14 2.1
Potassiumcarbonate 584-08-7 0.68 10.2
7440-44-0 0.1 1.5

Charcoal
133. ASENAPINE Trans-2-Methyl-5-Nitro- 65576-45-6
2,3,3a,12b-Tetrahydro-1H-
Dibenz[2,3:6,7]Oxepino[4,5- 11.85
C]-Pyrrole 0.79
Ethyl acetate fresh 141-78-6 0.1 1.5
Ethyl Acetate +Cyclohexane ---

fresh 0.1 1.5
Dichloromet
MDC fresh hane 0.1 1.5
N-Butyl alcohol fresh 71-36-3 0.1 1.5
Butanol fresh 71-36-3 0.1 1.5
110-16-7 4.5
Maleic acid 0.3
Liq ammonia 7664-41-7 0.35 5.25
CUCl in Con HCl 7758-89-6 0.48 7.2
Sodium nitrite 7632-00-0 0.18 2.7
Con HCl 7647-01-0 0.122 1.83
Dilute NaoH 1310-73-2 1.2 18

51
ANNEXURE V
Hydrogen pressure 1333-74-0 0.03 0.45
Palladium charcoal 7440-05-3 0.08 1.2
134. AXITINIB 319460-85-

0 15.75
Axitinib solvent 1.05
Dimethyl sulfoxide fresh 67-68-5 1 15
135. 147403-03-
0 12.3
AZILSARTAN Azilsartan 0.82
4-Hydroxymethyl-5-Methyl- 91526-18-0
1,3-Dioxol-2-One 0.22 3.3
K2CO3 584-08-7 0.78 11.7
P-TsCl 98-59-9 0.52 7.8
Acetic acid 64-19-7 0.142 2.13
MDC fresh 75-09-2 0.1 1.5
Acetone 67-64-1 0.1 1.5
Potassium Ethyl Hexanate 3164-85-0 0.38 5.7
4637-24-5 0.8 12
Di Methyl Acetal
136. 171887-03-
N-(2-amino-4,6-dichloro-5- 9 15
ABCAVIR SULPHATE pyrimidiyl)formaide 1
Sodium carbonate 497-19-8 2 30
(1S,2R)-4-amino-2- 172015-79-
cyclopentene-1-methanol 1
HCL 0.9 13.5
Iso Propyl Alcohol fresh 67-63-0. 1.1 16.5
Con Hydrochloric acid 7647-01-0 0.74 11.1
Triethyl ortho formate 122-51-0 0.1 1.5
Acetone fresh 67-64-1 0.1 1.5

52
ANNEXURE V
Con sulfuric acid 7664-93-9 0.288 4.32
Triethyle amine 121-44-8 1.68 25.2
Cyclopropyl amine 765-30-0 0.6 9
137. ATROVASTATIN 56507-37-0 9

CALCIUM Diketo compound 0.6
133825-81-
ATR-1 7 0.52 7.8
Sodium Bicarbonate 144-55-8 0.3 4.5
Iso Propyl Alcohol fresh 67-63-0. 0.05 0.75
Pivalic acid 75-98-9 0.088 1.32
Cyclohexane fresh 110-82-7 0.05 0.75
Calcium acetate 62-54-4 0.14 2.1
Dil hydrochloric acid 7647-01-0 1.5 22.5
Ethyle acetate fresh 141-78-6 0.05 0.75
t-butyl ether fresh 1634-04-4 0.2 3
78-93-3
Methyl ethyl ketone fresh 0.05 0.75
138. 34841-35-5 9.6

BUPROPION HCL 3'-chloropropiophenone 0.64
Bromine 7726-95-6 0.6 9
75-09-2
Methelene dichloride fresh 0.1 1.5
Iso Propyl alcohol fresh 67-63-0. 0.05 0.75
141-78-6 0.75
Ethyle acetate fresh 0.05
T-butyl amine fresh 75-64-9 0.4 6
10% hydrochloric acid 7647-01-0 1 15

53
ANNEXURE V
139. P-HYDROXY BENZYL 623-05-2 0.378

BISOPROLOL ALCHOL 5.67
FUMARATE
2-isopropoxy ethanol 109-59-1 0.4 6
p-toluene sulfonic acid 6192-52-5 0.02 0.3
K2CO3 584-08-7 0.04 0.6
TOLUENE 108-88-8 0.04 0.6
NaoH 1310-73-2 0.15 2.25
Methanol 67-56-1 0.1 1.5
epichlorohydrin 106-89-8 0.282 4.23
Isopropyl amine 67-63-0 0.18 2.7
MDC 75-09-2 0.1 1.5
ACETONE 67-64-1 0.1 1.5
FUMARIC ACID 110-17-8 0.18 2.7
140. 5-(Benzyloxy)-2-[4- 198479-63-

(Benzyloxy)Phenyl-3-1-[4- 9
(2-Hexamethyleneimine-1-
Yl-Ethoxy)Benzyl]-1H- 16.2
BEZEDOXIFENE Indole 1.08
7440-05-3
Palladium on carbon 0.12 1.8
Hydrogen 7722-84-1 0.02 0.3
Acetic acid 64-19-7 0.12 1.8
141. 1-(2,3,4,6-Tetra-O- 13992-25-1

Propionyl- β-D-
Glucopyranosyl)-4-Methyl-
3-[5(4-Fluorophenyl)-2- 19.83
CANAGLIFLOZIN Thienylmethyl]Benzene - 1.322
Sodum methoxide 124-41-4 0.07 1.05

54
ANNEXURE V
Heptane 142-82-5 0.1 1.5
Toluene + 108-88-3 0.1 1.5
142. 2-Ethoxy-1[2'-{1h- 139481-69-

TeD6:D214yl)- 9
CANDESARTAN Methyl]Benzimidazole-7- 12
CILEXETIL Carboxylic Acid 0.8
121-44-8
Triethyl Amine 0.18 2.7
Trityl Phenyl Hychloride 76-83-5 0.498 7.47
Methylene dichloride fresh 75-09-2 0.2 3
Potassium carbonate 584-08-7 0.06 0.9
Dimethyl sulfoxide 67-68-5 0.14 2.1
Cyclohexyl 1-Chloroethyl 99464-83-2

Carbonate 0.54 8.1
75-05-8 0.18 2.7

Sodium bicarbonate
Methanol fresh 67-56-1 0.6 9
Acetone + water fresh 67-64-1 0.1 1.5
143. 4-Sulfamoyl Phenyl 17852-52-7 9.3

CELECOXIB Hydrazine Hydrochloride 0.62
1-(4- Methylphenyl4,4,4- 720-94-2
Trifuloro Butane,3-Dione) 0.64 9.6
Aqueous In IPA 67-63-0 0.25 3.75
30% Ipa 67-63-0 0.6 9
144 CLOPIDOGREL 88744-36-9 9

BISULFATE 2-Chlorophenylglycine 0.6
Thionyl Chloride 7719-09-7 0.25 3.75

55
ANNEXURE V
Ethyle acetate 141-78-6 1.4 21
L-tartaric acid 87-69-4 0.476 7.14
K2hph4 75-09-6 0.38 5.7
Dichloro methane 75-09-2 0.22 3.3
Formaldehyde 50-00-0 0.7 10.5
Con hydrochloric acid 7647-01-0 0.36 5.4
2-thiophene ethanol 5402-55-1 0.46 6.9
145 DABIGATRAN 3-[(3-Amino-4- 212322-56-

methylaminobenzoyl)pyridin 0.
-2-ylamino]propionic acid 13.8
ethyl ester 0.92
Acetone 67-64-1 0.1 1.5
Methane sulfonic acid 0.14 2.1

42288-26-6
146. DAPAGLIFLOZIN 4-Chloro-7-Methoxy-6-(3- 199327-61-
Morpholin-4- 2 15.75
Ylpropoxy)Quinazoline 1.05
147. 3(S)-(+)-(1-Carbamoyl- 134002-26-

1,1diphenylmethyl) 9 16.5
DERIFENACIN Pyrrolidine L-(+)-Tartrate 1.1
5-(2-Bromoethyl)-2,3- 127264-14-
Dihydrobenzofuran 6 0.67 10.05
Dimethyl formamide fresh 68-12-2 0.1 1.5
Methelyene dichloride fresh 75-09-2 0.2 3
Hydrobromic acid 10035-10-6 0.3 4.5
148. 25038-36-2 16.5

DONEPEZIL Diene 1.1

56
ANNEXURE V
Platinum oxide 1314-15-4 0.12 1.8
Hydrogen gas 1333-74-0 0.02 0.3
Methanol 67-56-1 0.1 1.5
Methelye dichloride fresh 75-09-2 0.1 1.5
Diisopropyl ether fresh 108-20-3 0.10 1.5
Charcoal 7440-44-0 0.12 1.8
149. 2-N-Butyl-3-[4-(3-Di-N- 500791-70-8

Butyl
Aminopropoxy)Benzoyl]-5- 19.8
DRONEDARONE Aminobenzofurn Dioxalate 1.32
Aqeous Ammonia Solution 1336-21-6
(25%) 1.62 24.3
Methansulmide 3144-09-0 0.18 2.7
Ethyl acetate HCl 141-78-6 1.36 20.4
Methelye dichloride fresh 75-09-2 0.1 1.5
150. DESVENLAFAXINE 93413-69-5

SUCCINATE 11.52
MONOHYDRATE Venlafaxine 0.768
DMSO fresh 67-68-5 0.1 1.5
Sodium hydride 7646-69-7 0.276 4.14
Water fresh 7732-18-5 2 30
Thiophenol fresh 108-98-5 0.026 0.39
151. DULOXETINE 287737-72-8 10.41

HYDROCHLORIDE DTP HCl 0.694
NaBH4 16940-66-2 0.12 1.8
water 7732-18-5 1 15
1-fluronaphthalene 321-38-0 0.462 6.93

57
ANNEXURE V
Oxalic acid 144-62-7 0.398 5.97
Sodamide 7782-92-5 0.124 1.86
DMSO fresh 67-68-5 0.05 0.75
7664-41-7
Liq ammonia 5.8 87
Diiso propyle amine fresh 108-18-9 0.05 0.75
Phenyl chloro formate 1885-14-9 0.53 7.95
DBIA --- 1.18 17.7
acetone fresh 67-64-1 0.05 0.75
152. 183322-18-
1 11.55
ERLOTINIB KSM 0.77
3-ethylaniline 587-02-0 0.29 4.35
Methelyene dichloride fresh 75-09-2 0.1 1.5
153. 221615-75-
4 13.05
ETORICOXIB KSM 0.87
221615-73-
3-amino 2- chlloroacrolein 2 0.32 4.8
Trifluro acetic acid 76-05-1 0.38 5.7
Potassuin tert-butoxide 865-47-4 0.34 5.1
Tetrahydrofuran fresh 7664-39-3 0.1 1.5
IPA-Hexane fresh 0.1 1.5
Toluene fresh 0.1 1.5
Aq ammonia 7664-41-7 0.1 1.5
154. 41340-36-7 15
ETODLAC 7-ethyl tryptophol 1

58
ANNEXURE V
Methyl-9-oxopentanoate 30414-53-0 0.818 12.27
Con sulfuric acid 7664-93- 0.272 4.08
Dil Hydrochloric acid 7647-01-0 2 30
155. ESEITALOPRAM 59729-33-8 30.6

OXALATE Citalopram 2.04
Di-p-toluoyl-D-tartaric acid 71607-31-3
fresh 0.48 7.2
Methanol fresh 67-56-1 1.5

0.1
Water 7732-18-5 2 30
Oxalic acid 144-62-7 0.24 3.6
25% liq ammonia 1336-21-6 0.9 13.5
MDC fresh 75-09-2 0.1 1.5
Toluene fresh 108-88-03 0.1 1.5
TEA 121-44-8 0.26 3.9
124-63-0 0.28 4.2

Methane sulfonyl chloride
Iso propyl alcohol fresh 108-88-03 0.1 1.5
156. Ethyl2-[3-Cyano-4-(2- 160844-75-

Methylpropoxy)Phenyl]-4- 7
Methyl-5-Thiazole 17.55
FEBUXOSTATE Carboxylate 1.17
Hydroxylamine 5470-11-1
Hydrochloride 0.38 5.7
Acetone fresh 67-64-1 0.05 0.75

59
ANNEXURE V
D.M.Water fresh -- 0.05 0.75
157. 6334-18-5 7.5

2,3-Dichloro Benzaldehyde
FELODIPINE 0.5
Methyl aceto acetate 105-45-3 0.37 5.55
3 amino crotonic acid 103909-86- 0.33 4.95
Cyclo hexane fresh 110-82-7 25 375
Isopropyl alcohol fresh 067-63-0 0.05 0.75
Formic acid 64-18-6 0.1 1.5
Piperidine 110-89-4 0.242 3.63
158. 372-18-9 5.88

FLUCONAZOL 1,3-difuoro benzene 0.392
Chloroacetyl chloride 79-04-9 0.4 6
Methanol fresh 67-56-1 50 750
Aluminium chloride 7446-70-0 0.5 7.5
Water -- 1.6 24
Dil hydrochloric acid 7647-01-0 2 30
10% potassium carbonate 584-08-7 1 15
NaNo2 7631-99-4 0.2 3
Trimethyl sulfoxonium 1774-47-6

iodide 0.76 11.4
KOH 1310-58-3 0.1 1.5
4H-amino-l,2,4- trizole 584-13-4 0.288 4.32
159. 4-choro-4-hydroxy 42019-78-3 10.74

FENOFIBRATE Benzophenone 0.716
isopropyl-alpha-bromo 23426-63-3
isobutamate 0.644 9.66
IPA 67-63-0 2 30

60
ANNEXURE V
K2CO3 584-08-7 0.32 4.8
160. 76272-41-8 17.85

Garnisetron HCL EMA-HCl 1.19
MDC fresh 75-09-2 0.1 1.5
N-methyl -indazole-3- 50890-83-0

Carboxylic acid 0.784 11.76
Thinoyl chloride fresh 7719-09-7 0.168 2.52
DMF 624-49-7 0.156 2.34
TEA 121-44-8 0.57 8.55
Sodium bicarbonate 144—55-8 1 15
IPA fresh 67-63-0 0.4 6
161. 199327-61-
2 12.3
GAFITINIB KSM 0.82
3-Chloro-4-Fluoroaniline 367-21-5 0.35 5.25
Iso Propyl alcohol fresh 67-63-0 0.1 1.5
N-Propanol fresh 71-23-8 0.1 1.5
162. 64744-50-9 14.4

GABAPENTIN Gabapentin Lactam 0.96
50% HBr 10035-10-6 2 30
Water -- 1 15
Iso Propyl alcohol fresh 67-63-0 0.05 0.75
Diethylamine 109-89-7 0.46 6.9
163. 1-(4-Hydroxy-3- 876-02-8 6

ILOPERIDONE Methoxyphenyl) Ethanone 0.4

61
ANNEXURE V
1-Bromo-3-Chloropropane 109-70-6 0.38 5.7
Potassium Carbonate 584-08-7 0.18 2.7
6-Fluoro-3(4-Piperidinyl)-
1,2-Benzisoxazole
Hydrochloride 84163-13-3 0.62 9.3
Tartaric Acid 87-69-4 0.36 5.4
Ammonia Solution (25%) 108-88-03 1.2 18
164. 2-(N-Butyl)-3-(2’-Cy-4-
Ylmethyl)-4-Oxo-1,3- 14.88
IRBESARTAN Diazaspiro [4.4] Non-1ene 0.992
Tributyltin Chloride 1461-22-9 0.65 9.75
Xylene fresh 1330-20-7 0.1 1.5
Methyl-T-Butyl ether fresh 1634-04-4 0.1 1.5
IPA fresh 67-63-0 0.1 1.5
Sodiumazide 26628-22-8 0.54 8.1
Charcoal 7440-44-0 0.1 1.5
Hydrochloric acid 7647-01-0 0.692 10.38
165. ITOPRIDE 7306-46-9 8.1

HYDROCHLORIDE Vertroyl chloride 0.54
2-(4-aminomethyl) phenoxy) 20059-73-8
N,N dimethyl ethanamine)- 0.52 7.8
K2CO3 584-08-7 0.68 10.2
Toluene fresh 108-88-03 0.05 0.75
Acetone fresh 67-64-1 0.05 0.75
Con Hydrochloric acid 7647-01-0 1.1 16.5
166. N-[3-Chloro-4-(3- 231278-20-

Fluorobenzyloxy)Phenyl]-6- 9 11.1
LAPATINIB Iodoquinazolin-4-Amine 0.74
2- 104458-24- 0.182 2.73
(Methylsulfonyl)Ethanamine

62
ANNEXURE V
HCL 4
Sodiume Triacetoxy 56553-60-7

Borohydride 0.332 4.98
Diisopropyl Ethylamine 7087-68-5 0.4 6
Methanol 67-56-1 0.4 6
P-Toluene Sulfonic Acid 104-15-4 1.15 17.25
Tetrahydrofuran Fresh 109-99-9 0.2 3
167. 186204-35-
3-(1-Plperazinyl)-1,2- 3 8.85
LURASIDONE HCl benziso 0.59
1R,2R)-1.2,Cyclohexane 1121-22-8 0.786 11.79
Calcium hydroxide 1305-62-0 0.632 9.48
Bicyclo[2,2,1] hep-tane-2,3- 6713-41-3

exodicarboximide 0.422 6.33
1330-20-7
N-Xylene fresh 0.04 0.6
Toluene fresh 108-88-03 0.1 1.5
IPA fresh 67-63-0 0.2 3
67-64-1 0.04 0.6

Acetone fresh
168. N-(Triphenylmethyl)-5-(4'- 124750-51-

bromomethylbiphenyl-2-yl- 2
)tetrazole (BBTT) N-
(Triphenylmethyl)-5-(4'-
LOSARTAN bromomethylbiphenyl-2-yl- 18.15
POTASSIUM )tetrazole (BBTT) 1.21
Potassium hydroxide 1310-58-3 0.22 3.3
Charcoal 7440-44-0 0.12 1.8

63
ANNEXURE V
169. 30525-89-4 3.75

MEM CHLORIDE Paraformaldehyde 0.25
Methyl Cellulose 9004-67-5 0.63 9.45
Thionyl Chloride 7719-09-7 0.99 14.85
1,3,5 Trioxane fresh 110-88-3 0.1 1.5
170. Imidazo[1,2-a]pyridin-3- 17745-04-9 9.45

MINODRONIC ACID ylacetic acid 0.63
Phosphorous Acid 13598-36-2 0.196 2.94
Phosphorous Trichloride 7719-12-2 1.74 26.1
Dliute Hydrochloric Acid 7647-01-0 1.44 21.6
Tetramethylurea 632-22-4 0.23 3.45
171. 71320-77-9 16.05

Mixer Moclobemide
MOCLOBEMIDE 1.07
Toluene fresh 108-88-03 0.1 1.5
IPA fresh 67-63-0 0.1 1.5
7440-44-0
Charcol 0.1 1.5
497-19-8
Sodium carbonate 1.06 15.9
172. 91-01-0 12
MODAFINIL Benzhydrol 0.80
Thio Urea 62-56-6 0.288 4.32
Hydrobromic Acid 10035-10-6 2.4 36
Ammonia Solution (25%) 1336-21-6 1.08 16.2
Sulfuric Acid 7664-93-9 0.29 4.35
Hydrogn Peroxide. 7722-84-1 0.09 1.35
173. 56718-71-9 5.58

4-(2-methoxyethyl)phenol
Metoprolol TARTRATE 0.372
Epichlorohydrin 106-89-8 0.398 5.97

64
ANNEXURE V
sodium hydroxide 1310-73-2 0.1 1.5
108-88-03 0.05 0.75

Toluene fresh
isopropyl amine 7717-09-7 0.2 3
tartaric acid 64-19-7 0.36 5.4
174. 2-Nitrobenzylidine 79-16-3

Acetoaceticacid Isobutyl 12.15
NISOLDIPINE Ester 0.81
3-Amino Crotonic Acid 64544-91-8
Methyl Eater 0.32 4.8
Di Sodium Hydiogen 7558-79-4

Phosphate 0.39 5.85
Di Methyl Aminopyridine 1122-58-3 0.34 5.1
Acetone fresh 67-64-1 0.05 0.75
Toluene fresh 108-88-03 0.1 1.5
175. 108-88-03 10.2

CHLORO COMP
OMEPRAZOLE 0.68
Macrapto como 37052-78-1 0.55 8.25
NaOH 1310-73-2 0.378 5.67
Ammonium molybdate 12054-85-2

tetrahydrate 0.2 3
acetone fresh 67-64-1 0.05 0.75
WATER fresh. 7732-18-5 0.116 1.74
H2O2 7722-84-1 0.102 1.53
Sodium acetate 127-09-3 0.234 3.51
176. 93413-77-5 19.2

Venlafaxine HCL
O-DES VENLAFEXINE 1.28
Ethanthial 75-08-1 0.1 1.5

65
ANNEXURE V
Acetic acid 64-19-7 0.2 3
Toluene fresh 108-88-03 0.1 1.5
114057-15-
DMF fresh. 7 0.1 1.5
Hydrochloric Acid 7647-01-0 1.48 22.2
177. 144689-63-
4 16.2
OLMESARTAN Olmesartan Medoxomil 1.08
Methyl Triphenyl methyl 596-31-6
ester 0.53 7.95
Tritanol 76-84-6 0.52 7.8
Hydrochloric Acid 7647-01-0 1.02 15.3
178. 2-amino-4-fluoro 3800-06-4

PITAVASTIN Benzophenone 11.58
INTERMEDIATES 0.772
3-cyclopropyl-3-oxo 32249-35-7
propionic acid methyl ester 0.57 8.55
Concentric sulfuric acid 7664-93-9 0.04 0.6
Toluene fresh 108-88-03 0.1 1.5
Cyclohaxen fresh 110-82-7 0.1 1.5
con HCl 7647-01-0 2 30
10% sodium bicarbonate 144-55-8 4 60
NaHCo3 144-55-8 0.1 1.5

66
ANNEXURE V
179. PINYLPEROIC ACID 3162-29-6

1,2-methylene dioxy
Acetophenone
1.1
16.5
HCL 7647-01-0 1 15
180. PRAMIPEXOLE (6S)-N6-Propyl-4,5,6,7- 7681-52-9

DIHYDROHLORIDE tetrahydro-1,3- 11.1
MONOHYDRATE benzothiazole-2,6-diamine 0.74
Charcoal 7440-05-3 0.08 1.2
HCl 7647-01-0 0.5 7.5
181. 2-acetoxy-5-( α- 109904-26-9

cyclopropylcarbony1-2-
fluorobenzyl)-4,5,6,7-
PRASUGREL tetrahydro thieno[3,2- 14.4
HYDROCHLORIDE c]pyridine 0.96
Fresh Of ethyl ethyl ketone 78-93-3 0.1 1.5
Fresh Of Ipa 67-63-0 0.1 1.5
182. 105812-81-5
(-)trans carbinol 10.65
Paroxitine HCL 0.71
Dimethylethylamine 598-56-1 0.5 7.5
Benzenesulfphonyl chloride 98-09-9 0.5 7.5
364590-63-
Sodium methoxide (smo) 6 0.002 0.03
Fresh DMF 68-12-2 0.1 1.5
Fresh toluene 108-88-03 0.1 1.5
Sesamole 533-31-3 0.476 7.14
Phenylchloroformate 1885-14-9 0.46 6.9
KOH 1310-58-3 0.732 10.98
Con HCl 7647-01-0 0.36 5.4
183. -- 3.72
dihydronepol
Pinavarium Bromide 0.248

67
ANNEXURE V
4-(2-chlroethyl)morpholine 3240-94-6 0.372

5.58
Na2co3 497-19-8 0.68 10.2
IPA fresh 67-63-0 0.1 1.5
ACETONE fresh 67-64-1 0.1 1.5
2-bromo-veratyl bromide 53207-00-4 0.62 9.3
184. 85583-54-6 10.41

PIOGLIAZONE HCL EPNB
0.694
Hydrogen gas 1333-74-0 0.012 0.18
palladium carbon 7440-05-3 0.02 0.3
HBr 10035-10-6 0.414 6.21
Methyl acrylate 96-33-3 0.22 3.3
Sodium nitrate 7631-99-4 0.176 2.64
thiourea 62-56-6 0.194 2.91
Sodium acetate 127-09-3 0.30 4.5
Con hcl 7647-01-0 0.182 2.73
KHCO3 122-01-0 0.254 3.81
DMF 68-12-2 0.05 0.75
Con hcl 7647-01-0 0.182 2.73
64-17-5 0.5 7.5

50 % ETHANOL
methanol 67-56-1 1 15
copper oxide 1317-38-0 0.1 1.5
185. QUETIAPINE 78-94-4

FUMARATE 4.5
Ketone 0.3
POCl3 10025-87-3 0.22 3.3
Potassium carbonate 584-08-7 0.2 3
Fresh Toluene 108-88-03 0.2 3

68
ANNEXURE V
Fresh Piperazine 110-85-0 0.234

3.51
Fresh DMSO 67-68-5 0.04 0.6
Con Hydrochloric acid 7647-01-0 0.2 3
2-Chloro ethoxy ethanol 628-89-7 0.148 2.22
Sodium carbonate 497-19-8 0.18 2.7
Furamic acid 110-17-8 0.14 2.1
Fresh Ethanol 64-17-5 0.1 1.5
186. 117977-21-
RABEPRAZOLE SODIUM
Rabeprazole sulphoxide 6 15
1
NaOH 1310-73-2 0.81 12.15
Water 7732-18-5 1.2 18
Toluene fresh 108-88-03 0.1 1.5
187. 4-{4-[(5S)-5-(aminomethyl)- 898543-06-

RIVAROXABAN 2-oxo-1,3-oxazolidin-3- 1
yl]phenyl}morpholin-3- 12.15
one.HCL 0.81
5-Chlorothiophene-2- 42518-98-9
Carboxylchloride 0.45 6.75
Sodium Acetate 127-09-3 1.2 18
188. ROPINIROLE Ethyl-2-nitro-6-(N,N-di-n- 91374-25-3

HYDROCHLORIDE propylaminoethylphenyl)ace 18.75
tic acid.HCL 1.25
10% Pdc 20039-37-6 0.13 1.95
Triethyle amine 121-44-8 0.37 5.55
Fresh MDC 75-09-2 0.1 1.5
Fresh Methanol 67-56-1 0.1 1.5
Fresh Ethyle acetate 141-78-6 0.1 1.5

69
ANNEXURE V
189. 1258003-
RESPERIDONE 6-fluoro-3-(4-piperidinyl1,2
benzisooxazole 96-1
0.536 8.04
3-(2-chloroethyl-6,7,8,9- 63234-80-0
tetrahydro-2-methyl-4h-
pyrido(1,2.a)pyridimidine 4-
one 0.55 8.25
potassium carbonate 584-08-7 0.716 10.74
DMF fresh 68-12-2 0.05 0.75
190. 79617-89-3 0.85

Sertraline Hydrochloride
12.75
Setralone
74-89-5 0.1 0
Mono methylamine
141-78-6 0.05 1.5
Ethyl acetate
67-56-1 0.05 0.75
Methanol
1333-74-0 0.008 0.75
Hydrogen
7439-92-1 0.1 0.12
Pb
611-71-2 0.45 1.5
D--Mandelia acid
1310-73-2 1 6.75
10% NAOH
75-05-8 0.1 15
Acetonitrile
7647-01-0 0.2 1.5
HCl
191 (1-[3-(Benzyloxy)propyl]-5- 180468-42-
{(2R)-2-[2-(2,2,2- 2
Solifenacin Succinate trifluoroethoxy)
phenoxy]ethyl}amino)propyl
]indoline-7-Carbonitrile 1.19 3
Oxalate
144-55-8 0.212 17.85
Sodium bicarbonate
7722-84-1 1.164 3.18
Hydrogen peroxide
67-68-5 0.1 17.46
Dimethyl sulfoxide
192 Tadalafil 171752-68-4 1.18 1.5
Cis Carboline

70
ANNEXURE V
74-89-5 0.09
Methyl Amine 1.35
67-56-1 0.1 1.5
Methanol
IPA 67-63-0 0.06 0.9
7440-44-0 0.1 1.5

carbon
193 274693-26-
Ticagrelor
4 0.99 14.85
Isopropylidene Ticagrelor
7647-01-0 0.94 14.1
Con. HCl
67-56-1 0.1 1.5
Methanol
110-82-7 0.1 1.5
Cyclohexane
194 Topiramate 20880-92-6 10 150
BME-DFP
110-86-1 4.28 64.2
Pyridine
95-47-6 1 15
O-Xylene (Fresh)
THF (Tetrahydrofuran) 109-99-9 1 15
(Fresh)
Sulfuryl chloride 7791-25-5 6.96 104.4
110-54-3 3 45
n-Hexane (Fresh)
7664-41-7 1 15
Ammonia Gas
195 Vilazodone 163521-12-8
Hydrochloride 0.97 14.55
(Vilazodone) KSM
7647-01-0 0.09 1.35
Con. HCl
64-18-6 1.6 24
Formic Acid
196 Calcium Valsartan 137862-53-
Valsartan
4 1.16 17.4
7647-01-0 1.42 21.3

HCl
141-78-6 0.1 1.5
Ethyl Acetate
108-20-3 0.1 1.5
Di isopropyl ether
197 VortioxetineHydrbromide Tert-butyl-4-{2-[(2,4- -- 0.67 10.05
dimethylphenyl)sulfanyl]phe

71
ANNEXURE V
nyl}-3,5-dioxopiperazine-1-
Carboxylate
13292-87-0 1.25
Borane DMS 18.75
109-99-9 0.1 1.5
THF
7647-01-0 1.6 24
HCL
10035-10-6 1 15
HBr
198 Vemurafinib N-{3-[(5-bromo-1H- 918504-27-
pyrrolo[2,3-b]pyridin-3- 5
yl)Carbonyl]-2,4-
diflorophenyl}propane-1- 0.98 14.7
Sulfonamide
1679-18-1 0.34 5.1
4-Chlorophenylboronic acid
Tetrakistriphenylphosphinep 14221-01-3 0.46 6.9
alladium
75-05-8 0.1 1.5
Acetonitrile
199 WarfarinSodium clatharte 81-81-2 0.44 6.6
Warfarin Acid
67-63-0 0.12 1.8
IPA
67-56-1 0.48 7.2
Methanol
200 Ziprasidone HCl 87691-87-0
3-(1-Plperazinyl)-1,2,- 0.63 9.45

benziso Thiazole HCl
118289-55-
7
6-chloro-5-(2-chloroethyl 0.512 7.68

oxidole)
497-19-8 0.716 10.74
Sodium carbonate
67-63-0 0.1 1.5
Iso Propyl alcohol
7647-01-0 2 30
Con HCl
201 Vildagliptin 3-amino-1-adamantanol 702-82-9 0.606 9.09
1-chloroacetyl(s)-2- 207557-35-
cyanopyyrolidine 5 0.952 14.28
NAOH 1310-73-2 0.15 2.25

72
ANNEXURE V
7681-11-0 0.1
KI 1.5
109-99-9 0.1 1.5
THF
75-05-8 0.04 0.6
ACETONITRILE
202 MEMANTINE HCL 1,3-dimethyladamantane 702-79-4 0.976 14.64
H2SO4 7664-93-9 0.564 8.46
acetonitrile 75-05-8 0.3 4.5
ISOBUTANOL 78-83-1 0.04 0.6
KOH 1310-58-3 0.646 9.69
HCL 7647-01-0 2 30
ETHYL ACETATE 141-78-6 0.04 0.6
203 LINEZOLID 3,4-difluoronitro benzene 369-34-6 0.636 9.54
MORPHLINE 110-91-8 0.348 5.22
ETHYL ACETATE 141-78-6 0.04 0.6
K2CO3 584-08-7 0.28 4.2
METHANOL 67-56-1 0.3 4.5
PD/C CATALYST 7440-05-3 0.1 1.5
HYDROGEN 1333-74-0 0.03 0.45
IPA 67-63-0 0.04 0.6
EPICHLOROHYDRIN 106-89-8 0.368 5.52
DMF 68-12-2 0.04 0.6
POTASSIUM 1074-82-4
PTHALAMIDE 0.24 3.6
MDC 75-09-2 0.2 3
HYDRZINE HYDRATE 7803-57-8 0.2 3

73
ANNEXURE V
204 RAMELTEON 2-(8S)-1,6,7,8-tetrahy dro- 196597-81-

2H-indeno5,4-bfuran-8- 6
ylethanamine 1
15
PROPINOYL CHLORIDE 79-03-8 0.396 5.94
MDC 75-09-2 0.1 1.5
SODIUM CARBONATE 497-19-8 0.452 6.78
METHANOL 67-56-1 0.1 1.5
205 TIMOLOL MALEATE 3-hydroxy-4-morpholino- 30165-97-0

1,2,5-thiadiazole 0.6 9
S-(+)-epichlorohydrin 106-89-8 0.296 4.44
Methyl ethyl ketone 78-93-3 0.04 0.6
NAOH 1310-73-2 0.13 1.95
TERT-BUTYLAMINE 75-64-9 0.4 6
METHANOL 67-56-1 0.2 3
MALEIC ACID 110-16-7 0.372 5.58
206 SALEMETROL 6-(4- 1351281-

XINAFOATE phenylbutoxy)]hexyl]benzyl 52-1
amine – Hcl 0.856 12.84
methyl 5-(2-bromoacetyl)-2- 27475-14-5

benzyloxy 0.828 12.42
ETHYL ACETATE 141-78-6 0.04 0.6
NA2CO3 497-19-8 0.28 4.2
METHANOL 67-56-1 0.2 3
PD/C 7440-05-3 0.1 1.5
HYDROGEN 1333-74-0 0.03 0.45
DMF 68-12-2 0.5 7.5
WATER 7732-18-5 3 45

74
ANNEXURE V
THF 109-99-9 0.1

1.5
XINAFONIC ACID 77-92-9 0.43 6.45
LIALH4 16853-85-3 0.1 1.5
NAOH 1310-73-2 0.1 1.5
207 EZETIMIBE 149437-76-

4-(fluorobenzyl)buturic acid 3 0.82 12.3
4-(s)-phenyl oxazolidione 99395-88-7 0.652 9.78
N,Ndicylohexyl 538-75-0
carbodiamide (Dcc) 0.824 12.36
TOULENE 108-88-3 0.12 1.8
5%PD/C 7440-05-3 0.2 3
HYDROGEN 1333-74-0 0.04 0.6
4-FLUORO ANILINE 371-40-4 0.444 6.66
4-HYDROXY 123-08-0
BENZALDEHYDE 0.848 12.72
METHANOL 67-56-1 0.2 3
TRIMETHYL 75-77-4
SILYCHLORIDE 0.072 1.08
TRI ETHYL AMINE 204-469-4 0.4 6
50% H2SO4 7664-93-9 0.5 7.5
TETRAETHYL AMMONIUM 71-91-0

BROMINE 0.1 1.5
208 RITONAVIR Tert-butyl(2s,4s,5s)-5- 144163-85-9

amino-4-hydroxy-1-6-
diphenylhexan-2-yl
carbamate succinate (ksm-1) 0.716 10.74
4-nitrophenyl thiazol-5- 144163-97-

ylmethyl carbonate (ksm-2) 3 0.452 6.78
ETHYL ACETATE 141-78-6 0.2 3

75
ANNEXURE V
NA2CO3 497-19-8 0.28

4.2
WATER 7732-18-5 2 30
CON HCL 7647-01-0 1 15
(S)-2-(3-((2-isopropylthiazol- 154212-61-
4yl)methyl)-3-methylureido)-3- 0
methylbutanoic acid(KSM-3) 0.506 7.59
N,NDICYCLOHEXYL 538-75-0
CARBODIAMIDE (DCC) 0.332 4.98
TRIETHYL AMINE 121-44-8 0.2 3
N-HEPTANE 142-82-5 2 30
Benzo d(1,2,3) triaz-ol- 123333-53-

h2o (Hobt.h2o) 9 0.25 3.75
209 GLIMEPIRIDE 4-[2-(3-Ethyl-4-methyl-2- 119018-29-

carbonylpyrrolidine amido) 0
ethyl] benzene sulfonamide
(KSM-1) 0.846 12.69
trans-4-Methyl-cyclohexyl 32175-00-1
isocyanate (KSM-2) 0.336 5.04
POTASSIUM CARBONATE 584-08-7 0.35 5.25
ACETONE 67-64-1 0.1 1.5
WATER 7732-18-5 2 30
TOLUENE 108-88-3 0.04 0.6
ACETIC ACID 64-19-7 2.5 37.5

76
ANNEXURE VII
EFFLUENT TREATMENT PLANT

ETP DESCRIPTION:
Total 2 types of steams will be generated during the manufacturing process.
1) HIGH COD STEAM (>8,000 mg/l) + HIGH AMMONICAL NITROGEN STEAM

(> 100 mg/l)
2) LOW COD AND LOW TDS STEAM (FROM PROCESS + WASHING+ BOILER
BLOW DOWN + COOLING TOWER BLOW DOWN + DOMESTIC + SCRUBBER)
MANAGEMENT OF STEAMS
1) STEAM NO:-1:- HIGH COD STEAM + HIGH AMMONICAL NITROGEN STEAM
Unit will segregate HIGH COD steam-steam which is having more than 8,000 mg/l COD- &
HIGH Ammonical Nitrogen Steam- Steam more than 100 mg/l-from the source. It will be
directly subjected to CMEE of M/s. BEIL after neutralization.
2) STEAM NO:-2:- LOW COD AND LOW TDS STEAM
This steam will be treated in conventional effluent treatment plant along with Cooling Tower
Blow Down, Washing, and Scrubber Solution and with Domestic effluent.
Unit will develop primary, secondary and tertiary treatment to achieve the stipulated norms of
GPCB.
77
ANNEXURE VII
DIAGRAM OF HIGH COD & HIGH AMMONICAL EFFLUENT TREATMENT

PLANT
HIGH COD STEAM & HIGH AMMONICAL NITROGEN

STEAM
NEUTRALIZATION CHEMICALS
FILTER PRESS COLLECTION TANK TO CMEE OF M/s. BEIL
Sludge to Sludge Drying Bed
78
ANNEXURE VII
DIAGRAM OF CONVENTIONAL EFFLUENT TREATMENT PLANT
SUPPLY OF AIR FOR AERATION
LOW COD PROCESS STEAM + (C) BLOW

DOWN + WASHING + SCRUBBER
OVERFLOW
OVERFLOW
EQUALIZATION CUM
FILTER PRESS AERATION TANK-1 CLARIFIER-I AERATION TANK-II CLARIFIER-II
NEUTRALIZATION TANK
PARTIAL SLUDGE REUSED TO MAINTAIN MLSS & MLVSS PARTIAL SLUDGE REUSED TO MAINTAIN MLSS & MLVSS
LEACHATE
SUN DRYING BED
LEACHATE SLUDGE TO TSDF SITE

SUN DRYING BED
SLUDGE TO TSDF SITE TO DEEP SEA

COLLECTION TANK CARBON FILTER SAND FILTER
THROUGH PIPELINE

79
ANNEXURE VII
STEAM WISE EFFLUENT CHARECTERISTICS
Sr. Source of Waste Water Parameter Quality

No. Generation
1. Boiler blow down pH 8 - 9.5
TSS 25-50 mg/L
COD 50-70 mg/L
TDS 2500-3000 mg/L
2. Cooling Tower blow pH 8 - 9.5
down TSS 25-50 mg/L
COD 50-70 mg/L
TDS 1500-2000 mg/L
3. Washing pH 4-9
TSS 30-50 mg/L
COD 300-400 mg/L
TDS 1000-1200 mg/L
4. Process (LOW COD) pH 4-8
TSS 150-200 mg/L
COD <8000 mg/L
TDS 5000-8000 mg/L
Ammonical <100 mg/L
Nitrogen
5. Process Scrubber pH 5-8
TSS 25-50 mg/L
COD 100-150 mg/L
TDS 2000-4000 mg/L
7. HIGH COD containing pH 4-9
Steam TSS 150-200 mg/L
COD >8000 mg/L
TDS 5000-8000 mg/L
Ammonical >100 mg/L
Nitrogen
8. Domestic waste water pH 7.5 - 8.5
TSS 10-20 mg/L
COD 150-200 mg/L
TDS 250-400 mg/L

80
ANNEXURE VII
STAGE WISE REDUCTION IN EFFLUENT TREATMENT PLANT (CONVENTIONAL ETP)

After
Primary
After
Sr. Treatment GPCB
Composite After After After Sand Carbon
Parameters Units Discharge Stipulated
No. Sample ( After Clarifier-I Clarifier-II Filter Filter
Effluent Norms
Filter Press)
Quality
1. pH -- 4-9 6-9 6-9 6-9 6-9 6-9 6-9 5.5-9
2. TSS mg/l 150-200 80-90 50-60 30-40 20-30 20-30 20-30 100
3. TDS mg/l 5000-8000 5000-8000 5000-8000 5000-8000 5000-8000 5000-8000 5000-8000 ---
Ammonical
4. mg/l <60 <50 <50 <50 <50 <50 50
Nitrogen <50
2000- <250 <250

5. C.O.D. mg/l 6000-7000 4000-6000 500-800 <350 250
3000

81
ANNEXURE VII
STAGE WISE REDUCTION IN EFFLUENT TREATMENT PLANT

(HIGH COD ETP + HIGH AMMONICAL NITROGEN)
Neutralizati
on
Sr. Composite
Parameters Units (Effluent-
No. Sample Subjected to
M/s. BEIL-
CMEE)
1. pH -- 4-9 6-9
2. TSS mg/l 250-300 80-90
3. TDS mg/l 5000-8000 5000-8000
Ammonical
4. mg/l >100 >100
Nitrogen
5. C.O.D. mg/l >8000 >8000

82
ANNEXURE VIII
DETAILS OF WATER CONSUMPTION
TOTAL REMARKS
KL/Day
DOMESTIC 5 Unit will use fresh water for it.
GARDENING 9 Unit will use fresh water for it.
INDUSTRIAL WATER CONSUMPTION

PROCESS 67 Fresh Water:- 67 KLD
WASHING 8 Fresh water:- 3 KLD + Recycled
water:- 5 KLD)
BOILER 15 Fresh water:- 15 KLD
COOLING 35 Fresh Water:- 35 KLD
PROCESS 3 Fresh water:- 3 KLD
SCRUBBER
TOTAL 128 Fresh water:- 123 KLD + Recycled
(INDUSTRIAL) water:- 5 KLD
GRAND TOTAL 142 Fresh water requirement:- 161 KLD
DETAILS OF WASTE WATER GENERATION
TOTAL WASTE WATER REMARKS

KL/Day
DOMESTIC 5 Unit will treat domestic effluent
along with its industrial effluent.
GARDENING --
INDUSTRIAL WATER CONSUMPTION
PROCESS 71 High COD effluent subjected to
CMEE of M/s. BEIL= 35 KLD after
neutralization.
LOW COD effluent:- 36 KLD
subjected to in house effluent
treatment plant and subjected to M/s.
NCT.
WASHING 8 8 KLD WASHING WATER will be
treated in unit’s own effluent
treatment plant.
BOILER 12 Total 12 KLD Boiler Blow Down

83
ANNEXURE VIII
will be generated. Unit will use this

Boiler Blow Down water in the water
scrubber of Boiler. Total 6 KLD
effluent will be lost in to atmosphere.
Remaining 6 KLD saturated Water
will be used in Coal Handling and
Ash quenching. So unit will use
entire BOILER BLOW DOWN
water with in premises.
COOLING 5 5 KLD Cooling Tower Blow Down
water will be used for the washing
purpose.
SCRUBBER 3 3 KLD washing water will be
subjected to unit’s own effluent
treatment plant.
TOTAL 99 Total 99 KLD effluent will be
(INDUSTRIAL) generated from Industrial activity.
STEAM 1:- High Ammonical
Nitrogen Steam + HIGH COD steam
– send to incinerator of M/s. BEIL
after neutralization. (35 KLD)
STEAM 2:- LOW COD steam (47
KLD) - treated in unit’s own effluent
treatment plant.
Unit will use 12 KLD Boiler Blow
Down water within the premises for
the scrubber of Boiler and coal
handing & ash quenching.
Unit will use 5 KLD cooling tower
blow down for washing purpose.
GRAND 104 Domestic will also be treated along
TOTAL with industrial effluent.

84
ANNEXURE VIII
WATER BALANCE DIAGRAM

TOTAL WATER CONSUMPTION (142 KLD)
(FRESH:-137 KL/DAY + RECYCLE WATER: - 5 KL/DAY)
PROCESS BOILER
PROCESS (67 KLD) (15 KLD) WASHING COOLING TOWER DOMESTIC GARDENING
SCRUBBER (35 KLD)
(8 KL/DAY) (5 KLD) (9 KLD)
(3KLD) (3 KLD Fresh +
LOSS
5 KLD Cooling
Water Comes from Raw Evaporation loss
(3 KL/Day)
Blow Down)
Materials and due to 5 KL/Day BLOW DOWN LOSS
EFFLUENT
generation in process (12 KL/DAY) (30 KL/Day)
9 KLD GENERATION
(71 KLD) SCRUBBER SOLUTION BLOW DOWN
(3 KL/DAY) BOILER SCRUBBER (5 KL/DAY)
(12 KL/DAY)
HIGH COD SOAK PIT
(8 KL/DAY)
STEAM LOW COD LOSS BLOW DOWN USED FOR COAL (5 KL/DAY)
(35 KLD) (6 KL/Day) HANDLING AND ASH QUENCHING
(36 KL/Day)
(6 KL/Day)
ETP (53 KLD)

GIDC DISCHARGE
ETP CHEMICALS
ETP CHEMICALS:- (51 KL/Day)
(0.5 KL/Day) ETP SLUDGE WITH 50% MOISTURE: -2 KL/DAY
2 KL/DAY
NEUTRALIZATION TANK SLUDGE WITH 50% MOISTURE
(1 KL/DAY) SLUDGE DRYING BED: - 3 KL/DAY LOSS
(1 KL/Day)
ETP SLUDGE
SUBJECTED TO M/S. BEIL OF (2 MT/DAY)
CMEE (34.5 KLD)

85
ANNEXURE IX
DETAILS OF ENERGY CONSUMPTION

SR. IN KVA
NO ELECTRICITY TOTAL
1. Electricity 1000
DETAILS OF FUEL CONSUMPTION

Sr. Fuel Total Quantity of fuel
No.
1. Natural Gas OR 3600 m3/Day OR
Furnace Oil 3000 Lit/Day
2. Briquette OR 13 MT/Day OR
Coal 11 MT/Day
3. Diesel 50 Lit/Hr

86
ANNEXURE X
DETAILS OF HAZARDOUS WASTE GENERATION

Sr. Type of Category Source of Generation Total Mode of Disposal
No. Waste Hazardous
waste
generation
(MT/Annum)
1. ETP sludge 35.3 From ETP 730 Collection,
Storage,
Transportation,
Disposal at TSDF
site authorized by
2. Process Salt 35.3 From manufacturing 650 the GPCB.
Process
Product no:-
11,17,18,27,44,
.46
3 Used Oil 5.1 From lubricate of plant 5 Collection,
and machineries Storage,
And internally
reused in the
lubrication of plant
and machinery or
sell it to authorized
re-
refiners/recycler.
4 Discarded 33.1 Packing of raw materials. 50 Storage,
containers/ decontamination,
Empty transport and send
barrels/ to recycler or reuse
Bags/ Liners or send back to
supplier.
5 Spent 28.2 From manufacturing 25 Collection,

Catalyst Process Storage, and send
Product no:- to authorized unit
56,60,130,148
for regeneration.
6 Spent Carbon 28.3 From manufacturing 30 Collection,
Process Storage, and send
Product no:- for co-processing.
148,164,168,171,180,192
7 Distillation 26.3 From manufacturing 250
Residue Process
Product no:-
56,60,73,185,186,189,191

87
ANNEXURE X
8 Formic acid 26.3 From manufacturing 1425 Collection,

solution(50 Process Storage,
to 60% soln); Product no:- 5,27 And sell to those
9 Zinc chloride 26.3 From manufacturing 3120 units who are
Solution (20 Process
having permission
to 22% soln); Product no:- 5
Sodium 26.3 From manufacturing 4980 of RULE-9 or who
10
Bromide Process have applied under
Solution (10 Product no:- 4 RULE-9.
to 12% soln);
11 Aluminium 26.3 From manufacturing 3036
Chloride Process
Solution Product no:- 6,16,43
12 Acetic Acid 26.3 From manufacturing 810
(35% to 40% Process
solu) Product no:- 34,35
13 Scrubber -- From Scrubber 1095 It will be treated in
Solution unit’s own effluent
treatment plant.
(Sodium hypo
chloride solution,
Sodium bromide
solution, SBS
solution,
Ammonium sulfate
solution,
Hydrochloric acid
solution)
14 Off 28.4 -- 2 Collection,
Specification Storage,
Products And send to co-
processing.
15 Date Expired 28.5 -- 2
Products
16 Spent 28.6 From manufacturing 560 Collection, Storage

Solvents process and from SRP and send for co-
processing.
17 Sodium Product no:- 36,40, 43, 44 948 Collection, Storage

sulfate salt and sell to those
units who are
having permission
of rule-9 or who
have applied under

88
ANNEXURE X
rule-9 or dispose
through TSDF site.

89
ANNEXURE XI
DETAILS OF FLUE GAS EMISSION

Sr. Stack Stack Type of fuel Type of Quantity of Permissible APCM
No. attached to Height emission Fuel Limit
(m)
1. Boiler-1 30 Natural Gas / PM 2100 m3/Day 150 mg/NM3 Adequate
(2 MT/Hr.) Furnace Oil SO2 OR 100 ppm Stack
Nox 1800 lit/Day 50 ppm
Height.
2. Boiler-2 30 Coal/Briquette PM 11 MT/Day 150 mg/NM3 Bag Filter,
(5 MT/Hr.) SO2 OR 100 ppm Multi
Nox 13 MT/Day 50 ppm
Cyclone
Separator
and Water
Scrubber.
3
3. Thermic Fluid 30 Natural Gas / PM 1500 m3/Day 150 mg/NM Adequate
Heater Furnace Oil SO2 OR 100 ppm Stack
(4 Lacs Nox 1200 Lit/Day 50 ppm
Height
Kcal/Hr)
4. D.G.Set 12 Diesel PM 50 Lit/Hr 150 mg/NM3 Adequate
(750 KVA) SO2 100 ppm Stack
(2 Nos) Nox 50 ppm
Height

90
ANNEXURE XII
DETAILS OF PROCESS GAS EMISSION
Sr. Stack Attached To Stack Air Parameter Permissible

No. Height (m)
Pollution Limit
Control
System
PROCESS GAS EMISSION
1. Process Vessels 15 Water HCl 20 mg/Nm3
Scrubber Cl2 09 mg/Nm3
followed by SO2 40 mg/Nm3
Alkali Br2 09 mg/Nm3
Scrubber HBr 20 mg/Nm3
2. Process Vessels 15 Acid Ammonia 175mg/Nm3
Scrubber
 *Scrub solution will be subjected to in-house ETP.

91

ANNEXURE I TERMS OF REFERENCE

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ANNEXURE I

M/s. VIHITA CHEM PVT LTD (UNIT-III)

GROUP-1 (Sr. NO:- 1 to 3) (70 MT/Month)

1. 2,3,4,5–bis-O-[1-Methyl Ethyl 20880-92-6 70 For Topiramate

2. Di Methyl Formamide Di Methyl 4637-24-5 For Imatinib (API)

3. 4-Methyl Catechol Di-acetic acid 52589-39-6 For Watermelone

GROUP-2 (Sr No:-4 to 8 ) (40 MT/Month)

4. 4-Methyl Catechol 452-86-8 40 For Watermelon

5. Methylene dioxy phenol 533-31-3 For Paroxetine (API)

6. 4-Chloro-4’Hydroxy 42019-78-3 For Fenofibrate

7. 2-Bromo Veratryl Bromide 53207-004 For Pinaverium

8. 7-Ethyl tryptophol 41340-36-7 For Etodolac (API)

GROUP-3 (Sr No:-9 to 53) (25 MT/Month)

9. Di Methyl Formamide Di Iso 18503-89-4 25 For Cocaine (API)

10. 4-Methoxy Benzaldehyde 2186-92-7 For

11. Benzaldehyde dimethyl Acetal 1125-88-8 For Rosuvastatin

M/s. VIHITA CHEM PVT LTD (UNIT-III)

12. Dimethyl Acetamide Dimethyl 018871-66-4 For Zaleplon (API)

13. O-Benzyl hydroxyl amine 2687-43-6 For Larsartan (API)

14. Endo-9-methyl-9- 76272-56-5 For Granisetron

15. 2 3 Dihydrofuran 1191-99-7 For Etodolac

16. 2-Amino-4-fluoro Benzophenone 3800-06-4 For Pitavastatin (API)

17. 2-(2-ethoxy phenoxy)ethyl amine 64464-07-9 For Tamsulosin (API)

18. 2-(2-ethoxy phenoxy)ethyl amine 6781-17-5 For Tamsulosin (API)

19. N-(4-cyanophenyl)-glycin 42288-26-6 For Dabigatran (API)

20. 1-(2,'5' Dimethoxy phenyl amino 3600-87-1 For Midodrine (API)

21. Guanidine hydrochloride 50-01-1 For Triazine (API)

22. Guanidine Nitrate 506-93-4 For Trimethoprim

23. Guanidine thiocyante 593-84-0 For Triazine (API)

24. O-benzyl hydroxyl amine 2687-43-6 For Azaindoles (API)

25. Syringaldazine 14414-32-5 For Cholrine Test

26. 3-amino-2-thiophenecarboxylic 55341-87-2 For Tenoxicam (API)

27. ethyl 2-(3-cyano-4- 125971-96-2 For Atorvastatin

M/s. VIHITA CHEM PVT LTD (UNIT-III)

28. Sulfamerazine 127-79-7 For Antibiotic &

29 2-amino-4-methylpyrimidine 108-52-1 For Sulfamerazine

30 Methyl-2-amino-3-nitrobenzoate 57113-91-4 For Candesartan

31. Guanidine carbonate 593-85-1 For Triazine (API)

32. N-hydroxy phthalimide 524-38-9 For Catalyst

33 Alpha –Bromo -2-Chloro Phenyl 85259-19-4 For Clopidogrel

34 4-Methoxy-3- 592542-51-3 For Oncology

35 3,4-Dihydroxy Benzoic Acid 99-50-3 For Protochuic Acid

36 3,4- Dihydroxy Benzoic Acid 2150-43-8 For Erlotinib

37 Piperonylic Methyl Ester 326-56-7 For Fragrance

38 Ethyl 3-[(pyridin-2-yl)-amino]- 103041-38-9 For Dabigatran

39 3-nitro-4-methylamino benzoic 41263-74-5 For Dabigatran

40 Hydroquinone dimethyl ester 150-78-7 For Midodrine (API)

41 Malonic Acid Methyl Ester 38330-80-2 For Gycosylation

42 (1R,2R)-1,2 Cyclohexane 46022-05-3 For Lurasidon Hcl

43 1-Methylindazole-3-Carboxylic 50890-83-0 For Garnisetron Hcl

M/s. VIHITA CHEM PVT LTD (UNIT-III)

44 Isovanillic Acid 645-08-9 For Galantamine

45 2-Methyl-3-Oxo-Pentanoate 759-66-0 For Etodolac (API)

46 2-(2-ethoxy phenoxy)-mesylate 106463-17-6 For Tamsilosin HCl

47 3-(((2-methoxy-2- 106820-63-7 For Tenoxicam (API)

48 Methyl-6-methylnicotinate 2519-37-1 For Etoricoxib (API)

49 4-[(4-Methyl-1-piperazinyl)- 106261-48-7 For Lematinib (API)

50 2-(((2'-cyano-(1,1'biphenyl)-4-yl)- 139481-28-0 For Cilexetile (API)

51 Ndlic anhydride (endo- cis- 3853-88-1 For Lurasidone Hcl

52 4- Methoxy-3-(3- 895240-50-3 For Aliskiren (API)

53 3- cyclopropyl-3-oxo Propionic 32249-35-7 For Pitavastatin (API)

GROUP-4 (Sr No:-54To 127) (25 MT/Month)