Radiopharmaceutical

Gallium-67
 Introduction
2

Gallium-67
Is a photon radiotracer used for
scintigraphy in the form of salts such as
nitrate and citrate. When it is
administered, it binds to plasma proteins.
Especially to transferrin and lactoferrin
and particularly likes bonding with
inflammation sites.

Half Life
Gallium 67’s half life is 78
hours. Which means that it
takes 78 hours before its
concentration is reduced by
half
Radionuclide
Profile
3
Critical Organ Type of radiation emitted
The “target organ” or the Gallium 67 emits gamma
organ that will recieve the ray radiation.
largest radiation dose is the
colon. Although normal
distribution is in the liver,
spleen and bone marrow
 Uses
4

● diagnosing of sarcoidosis
● diagnosis of tuberculosis
● diagnosis of retroperitoneal fibrosis
● diagnosis of bronchogenic carcinoma
● localization of deep vein thrombosis
● localization of interstitial nephritis
 Techniques
5

Gallium 67 is given intravenously at 111-222 MBq and imaging is

done every 24, 48 and 72 hours.
Techniques

The study may consist of SPECT and SPECT-CT imaging but

have been replaced by 18-F-FDG-PET-CT imaging which
provides an earlier scan, better image quality and SUV
quantification.
Techniques
 Criticism
6

Gallium 67 is a valuable tool for diagnosing certain diseases

like sarcoidosis and tuberculosis and localization of fever of
unknown origin and deep vein thrombosis. It provides a better
evaluation of spinal infection, and with the utilization of
gallium citrate, it shows an earlier negative scan than that of
technetium used in bone scanning. However, it has poor
image quality than most scans, has a higher radiation dose
and cannot differentiate between osteomyelitis and cellulitis
 Sources
7

Thanks
https://radiopaedia.org/articles/gallium-67-sc
intigraphy-1