Exercise No.

1
Determination of Vital Signs

Questions:

1. How do clinical thermometers differ from each other?

2. What are the importance of determining an individuals’ vital signs?

3. Aside from diurnal variations in body temperature, what other factors may cause variations?

4. What is the clinical significance of an elevated body temperature? What causes the thermoregulatory
center to be reset to a higher temperature?

5.What are the importance of identifying the vital signs of the patient?

6.List of the pharmacologic and non pharmacologic modalities used in the treatment of an elevated
temperature and state the rationale for each.

Exercise No. 2
Body mass index Determination

Questions:

1.What are the methods of measuring body fat? How does it differ from BMI measurement?

2.Is BMI an accurate indicator of determining body fat? Why or why not?

3.What are the health consequences of having high BMI?

4. Can you interpret the BMI for adults as the same for that of a child or teen?

5. How can a low or high BMI affect the distribution of the following drugs; indicate if the dosing should
be increased or decreased:

A. thiopental

B. aminoglycosides

C. phenylpropanolamine

D. amiodarone

E. atorvastatin
 Exercise No. 3
Body fat Determination

Questions:

1. What are the factors that may influence a high triglyceride and HDL level in women?

2. Why it is important to test for the lipid level early in the morning?

3. What factors must be considered in screening for high cholesterol levels in children?

4. What can pharmacist advice to a patient with high triglyceride and total cholesterol values?

Exercise No. 4
Blood Glucose Monitoring

Questions:

1. What is the importance of monitoring a patients blood glucose level?

2. What is the proper storage of glucose test strips and how does improper storage affect the results?

3. What would be the normal fasting and non fasting blood glucose level?

4. What are the common anti hyperglycaemic drugs prescribed to type-2 DM?

Exercise No. 5
Methods of Drug Administration

Questions:

1. How are isosorbide dinitrate tablets administered to enable them to exhibit faster effect?

2. What antibiotics should not be taken with juices or milk? Why?

3. Why are some tablets chewed before swallowing?

4. When is the use of cream over ointment recommended?

5. What are the advantages of injectable method over the oral method?
 Exercise No. 6
Self Medication Monitoring

Questions:

1. Give the significance of proper monitoring the self medicated patient.

2. What are the risks of not monitoring the self medicated patient?

3. Differentiate self medicated patient and self prescription patient.

Exercise No. 7
Proper Handling Of Laboratory Animals

Questions:

1. What are the requirements on the following:

A. Animal accommodation

B. Bedding and nesting material

C. Animal Diet?

D. Water supply?

E. Transport?

2. What are the ways of animal monitoring?

3. What are the requirements for animal use?

4. What are the 3 R’s in animal use as stated by Rusell and Burch.

Exercise No. 8
Administration of Drugs and Blood Collection from Laboratory Animals

Questions:

1. What is an IACUC protocol (Application for Authorization for the conduct of Scientific Procedures
using animal)? What are the contents of the protocol?

2. What is RA 8485?

3. What are the factors affecting blood collection and administration?

4. What are the different sedatives and anesthetics that can be used to calm the animal and reduce the
pain that will be brought by the procedure?

Experiment No. 9
Determination of Antipyretic Activity

Questions:

1. Define antipyretic?

2. What is the use of Brewer’s yeast in the experiment?

3. Enumerate the different drug groups used as antipyretic agents.

4. Discuss the MOA of the following Drugs:

A. Paracetamol

B. Aspirin

Exercise No. 10
Determination of Analgestic Activity, Properties of Opiate Analgesics, Acetaminophen and
NSAIDS

Questions:

1. What is pain?

2. What is the pain threshold?

3. What are the different factors that will contribute to the development of pain?

4. Enumerate the different chemical mediators for pain.

5. Enumerate the different classification of opiate analgesics and NSAIDs based on chemistry and give
examples for each type.

6. State briefly the mechanisms involved in the analgesics activity analgesic drugs.

7. List down the parts of apparatus and give the function for each part.
 Exercise No. 11
Determination of Anti inflammatory Activity of Drugs

Questions:

1. What is inflammation?

2. Enumerate the different chemical mediator for inflammation.

3. What are the different factors that will contribute to the development of pain?

4. Give example of anti inflammatory drugs and mechanism of action.

5. Draw and label a plethysmometer apparatus.

Exercise No. 12
Determination of Diuretic Activity

Questions:

1. What are the clinical manifestations of potassium deficiency? Why is the ion potassium deficient?

2. What are the clinical cases of patients taking diuretics?

3. Why is there a need for you to place the animals in the schools’ animal holding facility for a certain
period of time?

4. How will you relate the exercise in your pharmacology subject?

5. What are the policies and guidelines of the government regarding the proper disposal of laboratory
animals?

6. Why is there a need for a metabolic cage in this particular exercise?