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ABSTRACT:
COVID-19 is a highly contagious and pathogenic coronavirus which emerged in China in December 2019, a pandemic
causing respiratory disease that poses a threat to human and public health and safety. The sudden release of COVID-19
revealed that zoonotic viruses and human to human transmission could be contaminated, disturbing and deadly. In view of
earlier studies on human coronaviruses and other zoonotic infections, it was observed that coronaviruses are have quite
common characteristics, especially in SARS-CoV and MERS-CoV. A comparison of the similarities and variations
between these three coronaviruses could benefit significantly to reduce the number of fatalities caused by Covid-19. A
comprehensive review was conducted for various original articles and review studies from PubMed, WHO, JAMA,
Lancet, NEJM and many more. The researcher selected 60 articles that have been published in journals or preprints in
compliance with keywords and qualifications for inclusion and exclusion. This study describes the fundamental virology
of Covid-19, including genomic and receptor characteristics, emphasizing its significant distinction from the previously
known coronaviruses. The researchers also summarizes current information about the epidemiological and pathological
characteristics of COVID-19, as well as recent developments in antiviral treatments and community-level interventions
for COVID-19.
This is where the final decisions was made for each study if
the researcher is going to use it or not.