Chickenpox

(Varicella)

Causes: Risk factors/ Predisposing

Etiology:
>acquired by the inhalation factors:
Varicella – Zoster
of airborne respiratory > age
Virus
droplets > health status
>direct contact with vesicles > patient who are
immunocompromised

Initial inhalation of
contaminated respiratory
droplet / direct contact with
the vesicles

Virus infects the conjunctivae

or mucosae of the Upper
Respiratory Tract

Viral proliferation in regional

lymph nodes of the upper 2 – 4 days
respiratory tact

Primary Viremia Post infection days of 4 – 6 days

Occurs in the body’s Second viral replication

internal organ

Secondary viremia 14 to 16 days of post infection

chicken pox (varicella)

Diffuse viral invasion of

capillary, endothelial
cells and the epidermis

VZV infection of cells of

the malpighian layer

Intercellular edema

Intracellular edema

Characteristic edema

Typical vascular rash