CLINICAL NEUROPSYCHOLOGY SEMINAR

THE NETWORK APPROACH TO

DEPRESSION AND ANXIETY

A Network Analysis Perspective

© Created & Designed by Eun-ho Lee – 2020 December

HIGHLY CITED RESEARCHERS
• Psychiatry and Psychology

Psychologists in the
Netherlands

BORSBOOM, DENNY CRAMER, ANGELIQUE EPSKAMP, SACHA FRIED, EIKO

NEUROPSYCHOLOGY SEMINAR 2
NEUROPSYCHOLOGY SEMINAR 3
SOME ISSUES OF DIAGNOSTIC SYSTEM

KEY POINTS
HETEROGENIETY
Clinical symptoms are very diverse and have
different forms.

PROBLEMS

CO-MORBIDITY DIMENSIONALITY
More than two disorders frequently coexist Severity of symptoms and clinical courses
at the same time. are very different.

NEUROPSYCHOLOGY SEMINAR 6
ASSUMPTIONS OF RDOC
• Mental illness are brain disorders; it is disorders of brain circuits.

• Dysfunction in neural circuits can be identified with the tools of

clinical neuroscience, including electrophysiology, functional
neuroimaging etc.

• Data from genetics and clinical neuroscience will yield biosignatures.

NEUROPSYCHOLOGY SEMINAR 8
NEUROPSYCHOLOGY SEMINAR 9
NEUROPSYCHOLOGY SEMINAR 14
NEUROPSYCHOLOGY SEMINAR 21
FUTURE ISSUES
1. Cross-sectional networks vs. Time-series networks
2. Computation of networks on single patients
3. External variables(e.g., biological & social) affecting network
structure and dynamics
4. Devising new methods for minimizing the burden on subjects, not
self-reports
5. Network approach for a guide therapeutic interventions
6. Dynamic computational network modeling to test theories
“ONE DEPRESSION IS NOT THE SAME
AS ANOTHER, AND THE TREATMENT
SHOULD NOT BE THE SAME FOR
EVERYONE.”

EIKO FRIED
QUESTIONS &
ANSWERS
eunho1130@gmail.com

DEPRESSEION CENTER
DEPARTMENT OF PSYCHIATRY
SAMSUNG MEDICAL CENTER