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(3) Cow-pea (4) Pigeon pea (1) 1:2:1 (2) 2:1 / 1:2
(3) 3:1 / 1:3 (4) 1:1
2. The year 1900 AD is highly significant for geneti-
cists due to the :- [RPMT-92,95] 10. Back cross is a cross between :- [RPMT-87]
(1) Discovery of genes (1) F1 x F1 (2) F1 xRecessive
(2) Principle of Linkage (3) F1 x Dominant (4) F1 x any parent
(3) Mendelian rediscovery
11. The cross between recessive to it's hybrid or it's F1
(4) Chromosome theory of heredity plant is called :- [RPMT-92,93,96]
3. During breeding the removal of anthers from a (1) Back cross (2) Test cross
flower is called :- [MP PMT-95] (3) Monohybrid cross (4) Dihybrid cross
(1) Anthesis (2) Pollination
12. What is the genotypic and phenotypic ratio of mono-
(3) Emasculation (4) Vasectomy
hybrid test cross :- [RPMT-96]
4. When a heterozygous tall pea plant of F1 genera- (1) 1:1 (2) 1:2
tion upon self fertilization produces tall and dwarf (3) 3:1 (4) 1:2:1
phenotypes it proves the principle of :-[RPMT -85,90]
(1) Dominance 13. What is the ratio of a progeny of cross between F1
heterozygous and recessive :- [RPMT-87]
(2) Segregation
(1) 3:1 (2) 1:2:1
(3) Independant assortement
(3) 1:1 (4) 2:1
(4) Inheritance & purity of gametes
14. Dihybrid cross proves the law of :- [AIPMT-92]
5. Mendel formulated the law of purity of gametes on (1) Segregation
the basis of :- [RPMT-90]
(2) Purity of gametes
(1) Dihybrid cross (3) Dominance
(2) Monohybrid cross (4) Independent assortment
(3) Back cross 15. How many types & in what ratio the gametes are
(4) Test cross produced by a dihybrid heterozygous :-
(1) 4 types in the ratio of 9:3:3:1 [AIPMT-92]
6. Mendelian monohybrid ratio is :- [RPMT-93]
(2) 2 types in the ratio of 3:1
(1) 1:2:1 (2) 3:1
(3) 3 types in the ratio of 1:2:1
(3) 9:3:1 (4) 9:3:4 (4) 4 types in the ratio of 1:1:1:1
7. In a monohybrid cross the genotypic ratio of the 16. How many gametes are produced in F1 generation
offspring in F2 generation is :- of a trihybrid :- [MP PMT-88]
[MP PMT-96, UP CPMT 2007, MP PMT 2005]
(1) 3 (2) 4
(1) 3:1 (2) 1:2:1
(3) 8 (4) 16
(3) 1:1:1:1 (4) 4:0
17. Which genotype represents a true dihybrid condi-
8. A cross between AaBB X aa BB yields a genotypic tion
ratio of :- [AIPMT-90] (1) tt rr (2) Tt rr [AIPMT-91]
(1) 1 AaBB: 1 aaBB (2) 1 AaBB : 3 aaBB (3) Tt Rr (4) TT Rr
(3) 3AaBB : 1 aa BB (4) All AaBb
18. Mendel enunciated how many principles (postulates) 27. In Mendel's experiments, colour of seed coat, na-
of inheritance :- [MP PMT-95] ture of flower, position of flower, colour of pod,
(1) One (2) Two height of stem, are called :- [RPMT-97]
(3) Three (4) Four (1) Alleles (2) Genotype
19. Mendelian ratio 9:3:3:1 is due to :- [RPMT-95] (3) Phenotype (4) All of the above
(1) Law of segregation
28. If 120 Plants are produced on crossing pure red
(2) Law of purity of gametes
and pure white flowered pea plants, than the ratio
(3) Law of independent assortment of offsprings will be :-
(4) Law of unit characters
(1) 90 Red : 30 White [RPMT-96]
20. In a cross between a pure tall plant with green pod (2) 30 Red : 90 White
& a pure short plant with yellow pod. How many
(3) 60 Red : 60 White
short plants are produced in F2 generation out of
16 :- [AIPMT-94] (4) All Red
(1) 1 (2) 3 29. According to Mendel's law of segregation the ratio
(3) 4 (4) 9 of F2 generation is :- [RPMT-96]
21. In a dihybrid cross between AABB and aabb the (1) 1:2:1 (2) 3:1
ratio of AABB, AABb, aaBb, aabb in F2 generation (3) 1:1 (4) 2:1
is :- [AIPMT-92-94]
(1) 9:3:3:1 (2) 1:1:1:1 30. Pea plants were more suitable than cattle for Men-
(3) 1:2:2:1 (4) 1:1:2:2 del's experiment because :- [CPMT-88]
22. A dihybrid ratio is :- [MP PMT-98] (1) There were no breeding records of cattles
(1) 1:1:1:1 (2) 3:1 (2) Pea plants can be self-fertilised
(3) 9:3:3:1 (4) 9:5:1:1 (3) Cattle are not easy to mantain
23. AABbCc genotype forms how many types of gam-
etes :- [AIPMT-98] (4) All pea plants have 2n chromosomes and fewer
(1) 4 (2) 8 genetic traits
(3) 2 (4) 6
24. Who rediscovered the results of Mendel's 31. An individual with two identical members of a pair
experiments :- [RPMT-97] of genetic factors is called :- [CPMT-81]
(3) Tschemark, Morgan, Correns 32. Two allelic genes are located on : [AFMC-84]
36. Mendel's law of segregation is based on separation 46. When flowers are unisexual then emasculation is
of alleles during :- [MP PMT-93] done in :-
(1) Gemete formation (1) Female (2) Male
(2) Seed formation (3) 1 & 2 both (4) None of these
(3) Pollination 47. How many plants are dihybrid in F2 generation of
(4) Embryonic development dihybrid cross :-
(1) One (2) Two
37. In a cross 45 tall & 14 dwarf plants were obtained, (3) Four (4) Sixteen
the genotype of parents was :- [BHU-93]
59. Which of the following is the unit of inheritance :- 69. Genotype - phenotype concept was first produced
(1) Phenotype (2) Genotype by :-
Male gametes 82. Which one of the following traits of garden pea
Female AB Ab aB ab studied by Mendel, was a recessive feature:-
75.
gametes ? AaBB AaBb aaBB aaBb [A I P M T– 2 0 0 3 ]
(3) 1/16 (4) 1/32 (1) All the offsprings will be tall with red fruit
(2) 25% will be tall with red fruit
77. According to Mendelism which character is
showing dominance- [AIPMT–2000] (3) 50% will be tall with red fruit
(1) Terminal position of flower (4) 75% will be tall with red fruit
(2) Green colour in seed coat 84. A trihybrid cross is made between two plants with
(3) Wrinkled seeds genotypes A/a B/b C/c how many offsprings of
(4) Green pod colour such cross will have a genotype a/a b/b c/c –
(1) 1/64 (2) 1/4
78. Due to the cross between TTRr × ttrr the resultant
progenies showed how many percent plants would (3) 1/16 (4) 1/32
be, tall, red flowered :– [AIPMT–2000]
85. How is the arrangement of Mendel’s selected seven
(1) 50% (2) 75% characters on four chromosomes :–
(3) 25% (4) 100% (1) One in ch. no. 1, 4 in ch. no. 4, one in ch.
79. Mendel obtained wrinkled seeds in pea due to no. 5, and one in ch. no. 7
deposition of sugars instead of starch. It was due (2) 2 in ch. no. 1, 3 in ch. no. 4, one in ch. no.
to which enzyme :– [AIPMT–2001] 5 and one in ch. no. 6
(1) Amylase (3) 3 in ch. no. 1, 1 in ch. no. 4, 2 in ch. no. 5
(2) Invertase and one in ch. no. 7
(3) Diastase (4) 2 in ch. no. 1, 3 in ch. no. 4, 1 in ch. no. 5
(4) Absence of starch branching enzyme and 1 in ch. no. 7
86. Out of three characters on chromosome no. 4, two 92. If a heterozygous tall plant is crossed with a ho-
characters indicate linkage and not mentioned by mozygous dwarf plant then what shall be the per-
Mendel. These characters were – centage of dwarf in offspring :-
(3) Pod form – pod colour 93. If a homozygous tall plant is crossed with a dwarf
(4) Pod position – stem length plant, what shall be the ratio of plants in offsprings :-
(1) All heterozygous tall
87. Mrs. verma has a autosomal gene pair 'Bb' and
(2) Two tall & Two dwarf
she contain x-linked gene 'd'. What is the percentage
of gamete which contain 'bd' genes :- (3) 1:2:1
(4) All homozygous dwarf
(1) 1/2 or 50% (2) 1/4 or 25%
(3) 3/4 or 75% (4) 1 or 100% 94. In a plant gene 'A' is responsible for tallness and
its recessive allele 'a' for dwarfness and 'B' is
88. When two different genotypes produce the same responsible for red flower colour and it's recessive
phenotype due to environmental difference, then allele 'b' for white flower colour. A tall and red
each one is known as :- flowered plant with genotype AaBb crossed with
(1) Phenotype (2) Phenocopy dwarf and red flowered (aaBb). What is the
percentage of dwarf-white flowered offspring of
(3) Progeny above cross :-
(4) Independent offspring (1) 50% (2) 6.25%
(3) 12.5% (4) 50%
89. The Punnett square shown below represents the
pattern of inheritance in dihybrid cross when yellow 95. In rabbit black skin (B) is dominant over brown skin
(Y) is dominant over white (y) and round (R) is (b) and short hair (S) is dominant over long hair (s).
dominant over wrinkled (r) seeds : If homozygous black–short haired male is crossed
with a homozygous brown–long haired female. All
YR Yr yR yr
F1–offspring are heterozygous black–short haired.
YR F J N R F1 male crossed with F1–female. In F2 generation
what is the percentage of homozygous black–short
Yr G K O S haired offspring :-
yR H L P T (1) 50% (2) 12.5%
yr I M Q U (3) 6.25% (4) 18.75%
A plant of type ‘H’ will produce seeds with the 96 How many different types of gametes can be formed
genotype identical to seeds produced by the plants by F1 progeny, resulting from the following cross
of :– : AA BB CC x aa bb cc [AIIMS– 2 0 0 4]
90. When a red flower homozygous pea plant is crossed 97. In order to find out the different types of gametes
with a white flower plant what colour is produced produced by a pea plant having the genotype AaBb,
in F1 :- [RPMT-87] it should be crossed to a plant with the genotype
(1) Monohybrid cross 109. Independent assortment of genes does not takes
(2) Reciprocal cross place when :– [AIPMT–2001]
(1) Seven chromosomes [BHU-94, AIPMT 2003] (1) 8 different gametes and 32 different zygotes
(2) Six chromosomes (2) 8 different gametes and 64 different zygotes
(3) Four chromosomes (3) 4 different gametes and 16 different zygotes
(4) Five chromosomes (4) 8 different gametes and 16 different zygotes
103. Two crosses between the same pair of genotypes 111. Phenotype of an organism is the result of –
or phenotypes in which the sources of the gametes (1) Mutations and linkages [AIPMT-2006]
are reversed in one cross, is known as :- (2) Cytoplasmic effects and nutrition
[A I P M T– 2 0 0 3 ]
(3) Environmental changes and sexual dimorphism
(1) Test cross (2) Reciprocal cross
(4) Genotype and environment interactions
(3) Dihybrid cross (4) Reverse cross
112. How many different kinds of gametes will be
104. If selfing occurs in the plant having genotype RrYy, produced by a plant having the genotype AABbCC?
then ratio of given genotype will be :- RRYY, RrYY,
(1) Three (2) Four [AIPMT-2006]
RRYy, RrYy [RPMT-2006]
(3) Nine (4) Two
(1) 1:2:2:4 (2) 1:2:2:1
(3) 1:1:1:1 (4) 2:2:2:1 113. Test cross involves – [AIPMT-2006]
105. The process of mating between closely related in- (1) Crossing between two genotypes with recessive
dividuals is :- [AIPMT-94] trait
(1) Out-breeding (2) Inbreeding (2) Crossing between two F1 hybrids
(3) Hybridisation (4) Heterosis (3) Crossing the F1 hybrid with a double recessive
106. Marriages between close relatives should be avoided genotype
because it includes more [MP PMT-90] (4) Crossing between two genotypes with dominant
(1) Recessive alleles to come together trait
(2) Mutations
114. A human male produces sperms with the genotypes
(3) Multiple births
AB, Ab, aB, and ab, aB, and ab pertaining to two
(4) Blood group abnormalities
diallelic characters in equal proportions. What is
107. Organisms with two or more than two types of geno- the corresponding genotype of this person :-
types in their tissues are called :- (1) AaBb (2) AaBB [AIPMT 2007]
(1) Wobble (2) Heterozygous (3) AABb (4) AABB
(3) Heterosis (4) Chimera
115. In pea plants, yellow seeds are dominant to green. 122. When an F1 individual is crossed with its either of
If a heterozygous yellow seeded plant is crossed the two parent. Then it is known as :-
with a green seeded plant, what ratio of yellow and
green seeded plants would you expect in F1 gen- [Uttaranchal PMT 2006]
eration :- [AIPMT 2007] (1) Test cross
(1) 50 : 50 (2) 9 : 1 (2) Back cross
(3) 1 : 3 (4) 3 : 1 (3) Reciprocal cross
116. Segregation of genes take place during :[AMU 2007] (4) Monohybrid cross
(1) Metaphase 123. How many pairs of contrasting characters were
(2) Anaphase chosen by Mendel for his study with garden pea:-
(3) Prophase (1) 3 (2) 5 [C.G. PMT 2004]
(4) Embryo formation (3) 7 (4) 14
117. An inherited character and its detectable variant is
124. If a homozygous red flowered plant is crossed with
termed as :- [AMU 2007]
white plant, the offspring will be :-
(1) unit factor (2) trait
(3) genctic profile (4) genotypic character (1) All red flowered [C.G. PMT 2004]
118. The genotype of a plant showing the dominant (2) All white flowered
phenotype and can be detemined by :[CBSE 2010] (3) Half red flowered
(1) Pedigree analysis (4) Half white flowered
(2) Back cross 125. How many types of genotypes are formed in F2
(3) Test cross progeny obtained from self polination of a dihybrid
(4) Dihybrid cross F1 :- [C.G. PMT 2005]
(4) Out of one pair of factors one is dominant and (3) 75% tall and 25% dwarf
the other recessive (4) 75% dwarf and 25% tall
120. A trihybrid cross involve three pair of characters 127. A test cross is performed : [UP CPMT 2001]
which will give rise to the F1 hybrids which are (1) by selfing of F2-generation plants
heterozygous for three genes. How many types of
(2) by selfing of F1-generation plants
gametes will be produced in both male and female-
[Uttaranchal PMT 2006]
(3) to determine whether F1-plant is homozgous or
heterozygous
(1) 2 (2) 4
(4) between a homozygous dominant and
(3) 6 (4) 8
homozygous recessive plant
121. Which one of the following traits studied by Mendel
128. Alleles are :- [UP CPMT 2002]
in garden pea was a recessive character :-
(1) Alternate forms of a gene
(1) Axial flower positon [Uttaranchal PMT 2006]
(2) Green cotyledon colour (2) homologous chromosome
(2) law of independent assortment which could be 140. Mendel's Law is valid only when :-[MP PMT 2003]
stated on the basis of segregation of gametes (1) Two F1 hybids are crossed
(3) incomplete dominance gave a new way to (2) One parent is crossed with F1 hybrid
mendelism (3) Two pure breeding contrasting characers are crossed
(4) a character controlled by a pair of unit factors (4) None of the above
134. If Aabb × aaBb, then genotypic ratio of its progeny 141. Mendel's laws of inheritance are applicable on the
will be :- [UP CPMT 2007] plants which :- [MP PMT 2005]
(1) 9 : 3 : 3 : 1 (1) Reproduce asexually
(2) 1 : 2 : 1 (2) Reproduce sexually
(3) 1 : 1 : 1 : 1 (3) Reproduce vegetatively
(4) 4 : 1 (4) All of the above plants
135. A pure tall and a pure dwarf plant were crossed 142. Genes are the :- [MP PMT 2005]
to produce offsprings. Offsprings were self crossed,
(1) Morphological units
then find out the ratio between true breeding tall
to true breding dwarf :- [MP PMT 2007] (2) Functional units
Que. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Ans. 1 3 3 2 2 2 2 1 4 4 2 1 3 4 4 3 3 4 3 3
Que. 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
Ans. 3 3 1 1 4 1 3 4 2 2 4 2 2 2 4 1 3 4 2 1
Que. 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Ans. 4 4 2 4 3 4 3 3 3 2 2 1 2 2 1 4 1 3 3 1
Que. 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80
Ans. 1 3 1 2 2 4 2 4 2 1 2 1 3 4 3 1 4 1 4 3
Que. 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100
Ans. 1 2 3 1 4 1 1 2 4 1 4 4 1 3 3 2 2 4 4 3
Que. 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120
Ans. 2 3 2 1 2 1 4 2 2 2 4 4 3 1 1 2 2 3 1 4
Que. 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140
Ans. 2 2 3 1 1 2 3 1 3 3 2 2 4 3 1 2 4 1 2 3
Que. 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160
Ans. 2 3 3 4 2 1 4 4 3 3 4 3 3 2 2 2 4 3 1 2
Que. 161 162 163
Ans. 2 3 4
Gene interaction - Allelic & Non-allelic, Polygenic Inheritance,
Cytoplasmic Inheritance
1. In Mirabilis & Antirrhinum plant the appearence of 8. When certain character is inherited only through
the pink hybrid (Rr) between cross of a red (RR) the female parent, it probably represents the case
and white (rr) flower parent indicates :- of :- [AIPMT-92]
2. Exception to Mendel's law is found in flower colour 9. Cytoplasmic male sterility is inherited :-
of :- [RPMT-96] (1) Maternally [MP PMT-86]
(3) 9:3:3:1 (4) 2:3:1 (1) Mirabilis jalapa (2) Pisum sativum
(3) Cicer aurietinum (4) Iberis amara
5. A white flowered mirabilis plant rr was crossed with
12. In case of incomplete dominance, F2 generation
red coloured RR, If 120 plants are produced in F2
has :- [BHU-95]
generation. The result would be :- [RPMT-96]
(1) Genotypic ratio equal to phenotypic ratio
(1) 90 uniformly coloured & 30 white
(2) Genotypic ratio is 3:1
(2) 90 Non-uniformly coloured & 30 white
(3) Phenotypic ratio is 3:1
(3) 60 Non-uniformly coloured & 60 white
(4) None
(4) All coloured & No white
13. In which type of inheritance the results are affected
6. When the phenotypic and genotypic ratios resem-
by reciprocal cross :-
ble in the F2 generation it is an example of :-
(1) Nuclear (2) Cytoplasmic
(1) Independant assortment [RPMT-85, DPMT-85]
(3) Blending (4) All the above
(2) Qualitative inheritance
(3) Segregation of factors 14. Incomplete dominance occurs in :-
(4) Incomplete dominance (1) Mirabilis (2) Antirrhinum
(3) Andulasion fowl (4) All of the above
7. Which one carries extra nuclear genetic material
15. Which cross yields red, white & pink flowers variety
(1) Plastids [BHU-87]
of dog flower :-
(2) Ribosomes
(3) Chromosomes (1) RR X Rr (2) Rr X RR
(4) Golgi-complex (3) Rr X Rr (4) Rr X rr
16. What shall be ratio in offspring when a roan cow is 24. In a dihybrid cross, when one pair of alleles show
crossed with a white bull :- incomplete dominance, genotypic ratio comes to
(1) 1:2:1 (2) 3:1 (1) 3 : 6 : 3 : 1 : 2 : 1
(3) 1:1 (4) All roan (2) 1 : 2 : 2 : 4 : 1 : 2 : 1 : 2 : 1
(3) 9 : 3 : 3 : 1
17. Phenotypic ratio in codominance :-
(4) 1 : 2 : 1
(1) 1:2:1 (2) 3:1
(3) 2:1 (4) 2:1:3 25. Which of the following is the example of co-
dominance :-
18. Which of the following is exception to Mendel's laws
(1) HbA HbA, IA IB (2) Hbs Hbs, IA IB
(1) Linkage
(3) HbA Hbs, IA IB (4) Hbs Hbs, IA IA
(2) Incomplete dominance
26. When dominant and recessive alleles express itself
(3) Co-dominance
together it is called :– [AIPMT–2001]
(4) All of the above
(1) Co–dominance (2) Dominance
19. A roan bull is bred to three cows. Cow A has the (3) Amphidominance (4) Pseudodominance
same genotype as the roan bull. cow B is red and
cow C is white. what proportions of roan cows are 27. Extranuclear inheritance occurs in :[AIPMT–2001]
expected in the offsprings of each group of cows :- (1) Killer Paramecium
(1) 2,1,1 (2) 1,2,1 (2) Killer Amoeba
(3) 1,1,2 (4) 3,1 (3) Euglena
(4) Hydra
20. The scientist who first discovered cytoplasmic - in-
heritance was :- 28. Genes for cytoplasmic male sterility in plants are
(1) Correns (2) Rhoades generally located in :- [A I P M T– 2 0 03 , 05]
(2) An autosomal linked dominant trait 40. When two independentaly assorting dominant genes
(3) Caused by substitution of valine by glutamic acid interact with each other to produce perticular phe-
notype but when they present alone they did not
in the beta globin chain of haemoglobin
produce phenotype they are called :-
(4) Caused by a change in a single base pair of DNA
(1) Complementary gene [AIPMT-96]
33. The most popularly known blood grouping is the (2) Supplementary gene
ABO grouping. It is named ABO and not ABC,
(3) Duplicate gene
because "O" in it refers to having :- [AIPMT-2009]
(4) Inhibitory gene
(1) No antigens A and B on RBCs
41. Polygenic genes show :- [AIPMT-96]
(2) Other antigens besides A and B on RBCs
(1) Identical phenotype
(3) Overdominance of this type on the genes for A
(2) Identical biochemistry
and B types
(3) Different phenotype
(4) One antibody only - either anti–A or anti–B on
(4) Identical genotype
the RBCs
42. AB - Blood group shows :- [AIPMT-89]
34. Mendel did not propose :- [BHU-91, MP PMT-90]
(1) Co-dominance
(1) Dominance
(2) Complete dominance
(2) Incomplete dominance
(3) Mixed inheritance
(3) Segregation
(4) Composite inheritance
(4) Independent assortment
35. Epistasis was discovered by :- [AIPMT-90] 43. ABO blood group is an example of :- [AIPMT-90]
(1) Johanson (2) Shull (1) Epistasis
(3) Bateson (4) Mendel (2) Multiple allelism
(3) Pleotropism
36. Inheritance of skin colour in human beings is an
(4) Complementary genes
example of :- [BHU-80]
(1) Complementary gene 44. A child is blood group is 'O'. His parents blood group
(2) Monogenic inheritance can not be :- [AIPMT-94]
(3) Epistasis (4) Co-dominance 59. Blood grouping in humans is controlled by:-
(1) 4 alleles in which IA is dominant
51. Epistatic gene differs from dominant gene in :-
(2) 3 alleles in which IA and IB are dominant
(1)Epistatic gene is non-allelic
(3) 2 alleles in which none is dominant
(2)Epistatic gene never express itself independently
(4) 3 alleles in which IA is recessive
(3)Epistatic and hypostatic genes are present at
different loci 60. In polygenic inheritance trait which controlled by
(4) All the above three pairs of genes. Two individuals which are
heterozygous for three alleles, crossed each other.
52. A dihybrid ratio of 1:4:6:4:1 is obtained instead of
Such type of cross produces what phenotypic ratio :-
9:3:3:1. This is an example of :-
(1) 1 : 2 : 1
(1) Complementary gene
(2) 9 : 3 : 3 : 1
(2) Supplementary gene
(3) 1 : 4 : 6 : 4 : 1
(3) Polygenic inheritance
(4) 1 : 6 : 15 : 20 : 15 : 6 : 1
(4) Incomplete dominance
61. In duroc jersey hog, the coat colour is dependant
53. A gene that shows it's effect on more than one char-
on two pairs of alleles, R and r and S and s. Any
acter is :-
genotype containing at least one R-gene and at
(1) Polygene (2) Pleotropic gene
least one S-gene results in red coat colour.The
(3) Multifactor gene (4) Multiple gene double recessive genotype results in white coat
54. In multiple allele system a gamete possesses :- colour. All other genotypes results in sandy coat
colour. If one hog with genotype "RrSs" mated with
(1) Two alleles (2) Three alleles
another hog with genotype "rrss" what kind of
(3) One allele (4) Several alleles
offsprings will be produced by above cross :-
55. An example of the quantitative trait in man is :- (1) 9 red : 6-sandy : 1 white
(1) Hair colour (2) 9 red : 3-sandy : 4 white
(2) Colour of eye (3) 12 red : 3-sandy : 1 white
(3) Skin colour (4) 1 red : 2-sandy : 1 white
(4) Shape of nose
62. Multiple alleles are present :- 68. When a red grain variety of wheat is crossed with
(1) In different chromosomes another white grain variety a F1-hybrid is produced.
On selfing of this F1- hybrid, how many offsprings
(2) At different loci on chromosome
of F2 - generation resemble phenotypically to it's
(3) At the same locus on homologous chromosomes parents (let grain colour of wheat controlled by three
(4) At the non homologous chromosome gene pairs )
(1) 2/16 (2) 20/64
63. Ratio of complementry genes is :– [AIPMT–2001]
(3) 15/64 (4) 2/64
(1) 9 : 3 : 4
(2) 12 : 3 : 1 69. Epistasis differs from dominance because
(3) 9 : 3 : 3 : 4 (1) In epistasis one gene pair mask the expression
(4) 9 : 7 of another pair of genes
(2) Epistasis is an allelic interaction
64. Which of the following is the example of pleiotropic (3) Many genes collectively controls a particular
gene :– [AIPMT–2002] phenotype
(1) Haemophilia (4) One gene pair independently controls a
(2) Thalaessemea particular phenotype
(3) Sickle cell anaemia
70. In a plant flower colour is the example of quan-
(4) Colour blindness titative trait and controlled by one gene pair. How
65. In totmato, genotype aabbcc produces 100g many plants show parental phenotype in F2 gen-
tomatoes and AABBCC produces 160g eration:–
tomatoes. What is contribution of each polygene 2 2
(1) (2)
in the production of tomatoes:- 16 4
(1) 10 g (2) 20 g 2 2
(3) (4)
(3) 30 g (4) 40 g 64 256
71. (A) Pleiotropic genes have multiple phenotypic
66. In a family, father has a blood group 'A' and mother effect.
has a blood group 'B'. Their children show 50% (B) Muliple alleles exhibit same phenotypic expres-
probability for a blood group 'AB' idicating that – sion.
(1) Father is heterozygous (C) Polygenes exhibit continuous variation.
(1) Statement (A), (B) and (C) are correct
(2) Mother is heterozygous
(2) Statement (A), (C) correct and (B) is incorrect
(3) Either of parent is heterozygous (3) Statement (A), (B) and (C) are incorrect
(4) Mother is homozygous (4) Statement (B) and (C) are correct and (A) is
incorrect
67. In a plant three dominant independently assorting
gene A, B and C are essential for production of 72. In a genetic cross having recessive epistasis, F2
purple pigment. If any of the genes or all three phenotypic ratio would be :- [AIPMT-90]
genes are present in recessive condition then flower (1) 9:6:1 (2) 15:1
is colourless
(3) 9:3:4 (4) 12:3:1
A B C
Raw material X Y Z pigment 73. Grain colour in wheat is determined by three pairs
of polygenes. Following cross AABBCC (dark colour)
A purple plant with genotype AABBCC crossed
x aabbcc (light colour), in F2 generation what
with a colourless plant with genotype aabbcc gives
proportion of the progeny is likely to resemble either
purple F1 hybrid. On selfing of F1– what proportion
parent ?
of coloured offspring in F2 –
(1) None [AIIMS-2005]
27 1
(1) (2) (2) Less than 5 per cent
64 64
9 37 (3) One third
(3) (4)
64 64 (4) Half
74. In man, gene producing the disease phenyl 81. Incomplete dominance is found in :-
ketonuria also produces a number of abnormal
(1) Pisum sativum [C.G. PMT 2005]
phenotypic traits, which are collectively syndrome.
This gene results mental retardation, widely spaced (2) Antrrhinum majus
incisors, pigmented patches on the skin and (3) Both Pisum sativum and Antirrhinum majus
excessive sweating such types of genes are called (4) None of these
(1) Polygene (2) Pleiotropic gene
82. The 1 : 2 :1 ratio with the pink flower in the F2
(3) Lethal gene (4) Supplimentary gene generation indicate the phenomenon of :-
75. Sickle cell anaemia induces due to :-[AIPMT–2001] (1) dominance [ J h ar kh and 2 0 05 ]
(1) Autosomal (2) Cytoplasmic (1) One pair of genes can completely mask the
(3) Y-linked (4) X-linked expression of another pair of genes
78. Inheritance of skin colour in humans is an example (2) One pair of genes independently controls a
of :- [AIPMT 2007] particular phenotype
(1) chromosomal aberration (3) One pair of genes enhances the phenotypic
(2) point mutation expression of another pair of genes
(3) polygenic inheritance
(4) Many genes collectively control a particular
(4) codominance
phenotype
79. ABO blood groups in humans are controlled by the
gene I. It has three alleles - IA, IB and i. Since there 86. The possible blood groups of children born to
are three different alleles, six different genotypes parents having A and AB groups are :-
are possible. How many phenotypes can occur? [UP CPMT 2001]
(1) Four (2) Two [CBSE 2010] (1) O, A (2) A, B, AB
(3) Three (4) One (3) O, A, B (4) O, A, B, AB
80. What would be the colour of flower in F1 progeny 87. A man with blood group B marries a female with
as a result of cross between homozygous red and blood group A and their first child is having blood
homozygous white flowered Snapdragon :- group B. What is the genotype of child :-
[C.G. PMT 2 004] (1) IAIB (2) IAIO [UP CPMT 2005]
(1) Red (2) White (3) IBIO (4) IBIB
(3) Red and White (4) Pink
88. A child with mother of blood group A and father 95. A polygenic trait is controlled by 3 genes A, B and
of blood group AB, will not have which of the C. In a cross AaBbCc × AaBbCc, the phenotypic
following blood group :- [UP CPMT 2006] ratio of the offsprings was observed as :
(1) A (2) B 1 : 6 : × : 20 : × : 6 : 1
(3) AB (4) O what is the possible value of x? [DPMT 2011]
90. If mother has blood group B, father has A group, (3) point (4) none of the above
the offspring will be of :- [MP PMT 2001] 97. Gene for cytoplasmic male sterility in plants are
(1) A (2) O generally located in the :- [AMU 2011]
91. Two nonallelic genes produces the new phenotype (2) mitochondrial genome
when present together but fail to do so (3) nucleaer genome
independently then it is called :– [AIPMT–2001] (4) cytosol
(1) Epistatisis 98. F2 generation in a Mendelian cross showed that both
(2) Polygene genotypic and phenotypic ratios are same as
(3) Non complimentary gene 1 : 2 : 1. It represents a case of :-
92. In incomplete dominance ratio of Red : Pink : White (1) Monohybrid cross with complete dominance
is :- [ W est B e ng al 2 0 0 7 ] (2) Monohybrid cross with incomplete dominance
(1) 1 : 2 : 1 (3) Co-dominance
(2) 1 : 1 : 2 (4) Dihybrid cross
(3) 1 : 2 : 2 99. A certain road accident patient with unknown blood
(4) 2 : 2 : 1 group needs immediate blood transfusion. His one
doctor friend at once offers his blood. What was the
93. A person with unknow blood group under ABO
blood group of the donor ? [AIPMT (Pre.) 2012]
system, has suffered much blood loss in an accident
and needs immediate blood transfusion. His one (1) Blood group O
friend who has a valid certificate of his own blood (2) Blood group A
type, offers for blood donation without delay. What (3) Blood group B
would have been the type of blood group of the
(4) Blood group AB
donor friend ? [AIPMT (Pre.) 2011]
100. When both alleles of a pair are fully expressed in
(1) Type B (2) Type AB
a heterozygote, theye are called :- [AMU 2012]
(3) Type O (4) Type A
(1) Lethals (2) Co-dominants
94. A polygenic inheritance in human beings is
(3) Semi-dominants (4) Recessive allele
(1) skin colour [RPMT 2011]
101. Which of the four couples claiming the baby with
(2) sickle cell anaemia O+ blood type are possibly the biological parents
(3) colour blindness of it? [Olympiad 2012]
Que. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Ans. 1 1 2 1 2 4 1 3 1 4 1 1 2 4 3 3 1 4 1 1
Que. 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
Ans. 3 1 3 2 3 1 1 2 2 4 2 4 1 2 3 3 4 3 3 1
Que. 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Ans. 3 1 2 3 4 3 4 4 3 1 4 3 2 3 3 4 4 1 2 4
Que. 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80
Ans. 4 3 4 3 1 3 1 4 1 2 2 3 2 2 2 2 2 3 1 4
Que. 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100
Ans. 3 3 2 2 1 2 3 4 1 4 4 1 3 1 3 3 2 2 1 2
Ans. 2 2 1 3
Linkage, Sex linkage, Sex Determination
1. What is the inheritance of colour blindness of both 8. Which of the following is not a sex linked charac-
parents having a normal vision but mother has a ters
recessive gene for colour blindness :-[AIPMT-90-96] (1) Haemophilia (2) Colour blindness
Son Daughter
(3) Hypertrichosis (4) Baldness
(1) 50% Nil
9. A gene located on Y-chromosome and therefore,
(2) 100% Nil
transmitted from father to son is known as:-
(3) Nil 100%
(1) Supplementary gene
(4) Nil Nil
(2) Complementary gene
2. What would be the nature of children if a colour (3) Duplicate gene
blind woman marries a normal man :- [AIPMT-95]
(4) Holandric gene
(1) Colourblind daughter & normal sons
(2) Colourblind sons and carrier daughters 10. The condition in which only one allele of a pair is
present in a diploid organism is known as :-
(3) Normal sons & carrier daughters
(1) Homozygous
(4) Normal sons & Normal daughters
(2) Heterozygous
3. A colourblind man marries a normal lady whose (3) Hemizygous
father was colour blind. If it produces two sons &
(4) Incomplete dominance
two daughters, how many of them would be suffer
(1) Both sons [AIIMS-85,AFMS-88] 11. Colourblindness is a :-
(2) Both daughters (1) Sex limited character (2) Sex linked character
(3) One son & one daughter (3) Sex influenced character (4) None
(4) Both sons & both daughters
12. Baldness in man is a :-
4. A colourblind daughter is born when :[MP PMT-98] (1) Autosomal character (2) Sex linked character
(1) Father is colourblind, mother is normal (3) Sex influenced character (4) 1 and 3 both
(2) Mother is colourblind, father is normal
13. A colourblind man marries a daughter of colourblind
(3) Mother is carrier, father is normal
father, then in the offsprings :-
(4) Mother is carrier, father is colourblind
(1) All sons are colourblind
5. Hypertrichosis is :-
(2) All daughters are colourblind
(1) Holandric character
(2) X-Linked character (3) Half sons are colourblind
19. In a cross between individuals homozygous for (a, 25. The linkage map of X-chromosome of fruitfly has
b) and wild type (+ +). In this cross 700 out of 1000 66 units, with yellow body gene (y) at one end and
individuals were of parental type. Then the distance bobbed hair (b) gene at the other end. The
between a and b is :- recombination frequency between these two genes
(y and b) should be :- [A I P M T– 2 0 0 3 ]
(1) 70 map unit (2) 35 map unit
(1) 60% (2) > 50%
(3) 30 map unit (4) 15 map unit
(3) 50% (4) 100%
26. Pattern baldness, moustaches and beard in human 34. Which of the following show linkage group in
males are examples of [A I P M T– 2 0 0 3 ] coupling phase :-
(1) Sex linked traits
(2) Sex limited traits (1) (2)
(3) Sex differentiating traits
(4) Sex-determining traits
(3) (4)
27. When a cluster of genes show linkage behaviour
they :- [A I P M T– 2 0 0 3 ] 35. The longer the chromosome of an organism, the
(1) Do not show a chromosome map more genetic variability it gets from :-
(2) Show recombination during meiosis (1) Independent assortment
(3) Do not show independent assortment (2) Linkage
(4) Induce cell division (3) Crossing over
77. In Drosophila, the sex is determined by :- 83. A diseased man marries a normal woman. They
get three daughters and five sons. All the daugh-
(1) The ratio of number of X–chromosomes to the ters were diseased and sons were normal. The gene
sets of autosomes [A I P M T– 2 0 0 3 ]
of this disease is :– [AIPMT–2002]
(2) X and Y chromosomes (1) Sex linked dominant (2) Sex linked recessive
(3) The ratio of pairs of X-chromosomes to the pairs (3) Sex limited character (4) Autosomal dominant
of autosomes
84. Which one of the following is the most suitable
(4) Whether the egg is fertilized or develops medium for culture of Drosophila melanogaster ?
parthenogenetically (1) Moist bread [AIPMT-2006]
87. Select the corrrect statement from the ones gives (2) mitosis and meiosis
below with respect to dihybrid cross : [CBSE 2010] (3) fertilzation and mitosis
(1) Genes loosely linked on the same chromosome (4) fertilization and amitosis
show similar recombinatios as the tightly linked 95. Haemophilic female marries normal male, the
ones theoretical ratio of their offsprings regarding
(2) Tightly linked genes on the same chromosome haemophilia will be :- [UP CPMT 2005]
show very few recombinations (1) All offsprings are haemophilic
(3) Tightly linked genes on the same chromosome (2) All girls are haemophilic
show higher recombination
(3) All sons are haemophilic
(4) Genes far apart on the same chromosome show
(4) half daughters and half sons are haemophilic
very few recombinations
96. Gynandromorphs are animals having :-
88. Who postulated the 'Chromosome Theory of
[UP CPMT 2006]
Inheritance' :- [C.G. PMT 2 004]
(1) same sex in all cells of the body
(1) De Vries (2) Mendel
(2) both sexes in all cells of the body
(3) Sutton and Boveri (4) Morgan
(3) same sex in different cells of the body
89. Drosophila melanogaster has :-
(4) different sexes in different cells of the body
[C.G. PMT 2 004]
(1) 2 pairs of autosomes and 1 pair of sex 97. In male grass hoppers and moths there are two
chromosomes pairs of autosomes and :- [UP CPMT 2006]
(2) 3 pairs of autosomes and 3 pairs of sex (1) X only (2) X and Y
chromosomes (3) Y only (4) none of these
(3) 1 pairs of autosomes and 3 pairs of sex 98. Which of the following symbols are used for
chromosomes representing sex chromosome of birds :-
(4) 3 pairs of autosomes and 1 pairs of sex
[UP CPMT 2007]
chromosomes
(1) ZZ – ZW (2) XX – XY
90. Which one of the following is associated with sex-
linked inheritance :- [B ihar 2 00 2] (3) XO – XX (4) ZZ – WW
(1) Night-blindness (2) muscular dystrophy 99. Gene for colourblindness is located on :-
[MP PMT 2007]
(3) astigmatism (4) Polydactyly
(1) Y chromosome (2) 13th chromosome
91. Haemophilia is :-
(3) X chromosome (4) 21th cromosome
(1) deficiency disorder [B ihar 2 00 1]
100. X-linked recessive gene is :- [MP PMT 2007]
(2) male sex chromosome disorder
(1) always expressed in male
(3) female sex chromosome disorder
(2) always expressed in female
(4) autosomal disorder
(3) lethal (4) sub lethal
92. Sex determination ratio in an organism is given
101. Linkage was first studied by :- [MP PMT 2001]
X
by 1.5 , then organism will be :-[Bihar 2001] (1) Darwin
A
(2) Morgan
(1) male (2) female
(3) Bateson and Punnett
(3) super female (4) intersex
(4) Mendel
102. In man sex linked characters are mainly transmitted 109. In Drosophila sex index of super female is :-
through :- [MP PMT 2005] (1) 1 (2) 0.5
(1) X-chromosome
(3) 1.5 (4) 0.67
(2) Autosomes
110. If X/A Ratio of two Drosophila is 0.6 and 0.33
(3) Y-chromosome respectively what would be their sex :-
(4) X-chromosome, Y-chromosome and Autosomes
(1) Female & male
103. Klinefelter's syndrome has chromosome
(2) Super female & super male
arrangement :- [MP PMT 2005]
104. If a colourblind woman marries with a normal man. 111. Which of the following genotype represent intersex
The offspring will be :- [MP PMT 2005] Drosophila :-
(1) All colourblind (1) 2A + XXX (2) 2A + XXY
(2) All daughters normal and all son will be (3) 3A + XXY (4) 2A + XY
colourblind 112. Which one of the following conditions correctly
(3) All normal describes the manner of determining the sex in the
given example ? [AIPM T (Pre.) 201 1]
(4) All daughters will be colourblind and all sons
(1) Homozygous sex chromosomes (ZZ) determine
will be normal
female sex in Birds.
105. If somatic cells of a human male contain single (2) XO type of sex chromosomes determine male
Barrbody, the genetic composition of the person sex in grasshopper
would be :- [MP PMT 2001] (3) XO condition in humans as found in Turner
(1) XYY (2) XXY Syndrome, determines female sex.
(3) XO (4) XXXY (4) Homozygous sex chromosomes (XX) produce
male in Drosophila
106. If a colourblind man is married to a normal woman,
then from the point of view of disease, their 113. Which one of the following conditions of the zygotic
offsprings will be :- [MP PMT 2002] cell would lead to the birth of a normal human female
child ? [ AI PM T ( M ain s ) 20 11]
(1) All sons will be colourblind
(1) One X and one Y chromosome
(2) All daughters will be colourblind (2) Two X chromosome
(3) all sons and daughters will be normal (3) Only one Y chromosome
(4) All sons and daughters will be colour blind (4) Only one X chromosome
114. Walter Sutton is famous for his contribution to :-
107. The theory where ratio between the number of
(1) Gentic engineering [DPMT 2011]
X-chromosomes and number of complete sets of
(2) Totipotency
autosomes will determine the sex is known as :-
(3) Qantitative genetics
[MP PMT 2002]
(4) Chromosomal theory of inheritance
(1) Chromosome theory of sex determination 115. If a colour blind man marries a girl who is normal
( h o m o z y g o u s ) f o r t hi s ch a r a c t r , t h e n
(2) Genic balance theory of sex determination genotypically :- [AMU 2011]
(3) Harmonal balance theory of sex determination (1) sons and daughters will be normal
(2) sons wil be colour blind, daughters will be normal
(4) environmental sex determination
(3) sons will be normal, daughters wil be carriers
108. Sex determination in humans takes place by :- (4) both sons and daughters will be colour blind
116. Frequency of crossing over will be relatively more
(1) sex chromosomes of father [MP PMT 2004]
if :- [AMU 2011]
(2) measurement of sperm (1) distance between the two genes is less
(2) distance between the two genes is more
(3) measurement of ovum
(3) linked genes are more
(4) sex chromosomes of mother (4) both (2) & (3)
117. Presence of recombinants is due to :-[AMU 2011] 121. Represented below is the inheritance pattern of a
(1) crossing over (2) linkage
certain type of traits in humans. Which one of the
(3) lack of independent assortment
(4) all of the above following conditions could be an example of this
118. Consider the following human disorders : i. pattern? [AIPMT (Mains) 2012]
Haemophilia ii. Down's Syndrome iii. Cystic fibrosis
iv. Colour bilindness v. Night blindness. Which of
these disorders exhibit 'Mendelian' pattern of
Female Male
inheritance? [Olympiad 2011]
Mother Father
(1) ii, iii and iv (2) i, ii and iii
(3) i, iii, and v (4) i, iii and iv
Daughter Son
119. A man and woman are both affected by vitamin D
resistance rickets, which is a dominant sex-linked
allele. All of the female offsprings of this couple are
affected with rickets but some of the male offsprings (1) Haemophilia (2) Thalassemia
are not. What are the genotypes of the parents? (3) Phenylketonuria (4) Sickle cell anaemia
[Olympiad 2011] 122. Depending upon the distance between any two
(1) Both are homozygous for the trait. genes which is inversely proportional to the strength
(2) The woman has two dominant alleles and man of linkage, cross overs will vary from :-[AMU 2012]
has one dominant allele. (1) 50-100% (2) 0-50%
(3) Both parents have only recessive alleles. (3) 75-100% (4) 100-150%
(4) Each parent has only one dominant allele. 123. The number of linkage group of E.Coli is/are :-
120. A normal visioned man whose father was (1) One (2) Two [MP PMT 2012]
colour-blind marries a woman whose father was also (3) Four (4) Six
colour blind. They have their first child as a daughter. 124. Genes are located in :- [MP PMT 2012]
What are the chances that this child would be (1) Ribosomes (2) Lysosomes
colour-blind? [AIPMT (Pre.) 2012] (3) Chromosomes (4) Spherosomes
(1) 25% (2) 50% 125. Crossing over takes place in :- [MP PMT 2012]
(3) 100% (4) Zero percent (1) mitotic cells (2) meiotic cells
(3) mutating cells (4) amitotic cells
Que. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Ans. 1 2 3 4 1 4 2 4 4 3 2 4 3 1 4 2 1 3 3 2
Que. 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
Ans. 1 2 2 1 3 2 3 1 2 4 4 3 2 1 3 2 2 2 2 3
Que. 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Ans. 4 3 3 3 1 2 1 2 3 2 2 2 1 1 2 2 3 4 2 4
Que. 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80
Ans. 4 3 2 1 4 1 2 4 1 1 2 3 2 3 1 3 1 3 3 4
Que. 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100
Ans. 3 4 1 3 4 4 2 3 4 2 3 3 1 1 3 4 1 1 3 1
Que. 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120
Ans. 3 1 2 2 2 3 2 1 3 3 3 2 2 4 1 2 1 4 4 4
Que. 121 122 123 124 125
Ans. 1 2 1 3 2
EXERCISE-4
Human genetics, Population genetics, Gene Expression, Gene
Regulation, DNA finger printing, Cloning, Human genome project
1. There are two alleles (A1 & A2) out of which one 8. A tobacco plant heterozygous for albinism is self-
(A1) has nil abundance in a population then the pollinated and 1200 seeds are subsequently ger-
abundance of second allele (A2) is :- [A IIM S-9 6] minated. How many seedlings would have the pa-
(1) 0.25 (2) 1.00 rental genotype :-
(3) 0.40 (4) 0.50 (1) 900 (2) 600
(3) 1200 (4) 300
2. If a normal woman marries an albino man and their
offsprings are half albino, half normal the woman 9. Which one of the following character in man is con-
is :- [MP PMT-98] trolled by recessive gene :-
(1) Homozygous normal (1) Colourblindness (2) Woolly hair
(2) Heterozygous normal (3) Brachy-dactyly (4) Curly hairs
(3) Homozygous recessive
10. Any changes in gene frequency in a population is
(4) Homozygous dominant
called :-
3. Which is a dominant trait :- [MP PMT-88] (1) Gene flow (2) Genetic drift
(1) Colour blindness (3) Gene pool (4) Gene conservation
(2) Albinism
11. The migration of gene in to a population from other
(3) Haemophilia
population by interbreeding is called
(4) Rh factor
(1) Gene pool (2) Gene flow
4. Parents are carrier for albinism. What will be the (3) Genetic drift (4) Gene erosion
first three children :- [MP PMT-88]
(1) Some normal, heterozygous & albino 12. What is the probability of three daughters to a
couple in three children :-
(2) All normal
(3) All heterozygous albino 1 1
(1) (2)
(4) No normal 4 8
1 1
(1) (2) [A I P M T– 2 0 0 4]
4 8
(1) Character is dominant and carried by X
1 1 chromosome
(3) (4)
32 16
(2) Character is carried by Y chromosome
18 Given below is a pedigree chart of a family with (3) Character is sex linked recessive
five children. It shows the inheritance of attached
(4) Character is autosomal recessive
ear–lobes as opposed to the free ones. The squares
represent the male individuals and circles the female 22. In pedigree analysis symbol is used for
individuals
(1) Heterozygous for autosomal recessive
(2) Affected individuals
(3) Death
(4) Carrier for sex linked recessive
1 1
(1) (2)
3 2
2 1
(3) (4)
3 4
(1) RR (2) Rr 1 1 1 1
(1) (2) (3) (4)
(3) rr (4) 1 or 2 5 20 10 2
35. In a random mating population frequency of 42. Which of the following processes affect the Hardy-
dominant allele is 0.7. What will be the frequency Weinberg Equilibrium to cause variation at the ge-
of recessive phenotype :–
netic level :- [AMU 2007]
(1) 0.49 (2) 0.09
(1) Mutation and Recombination
(3) 0.3 (4) 0.21
(2) Gene migration and Genetic drift
36. A plant is heterozygous and is designated Bb and
(3) Natural Selection
produces two kinds of gametes B and b. The prob-
ability of b gamete fertilising B or b is :- (4) All the above
(1) 1/2 (2) 1/1 [DPMT-83] 43. A gene containing multiple exons and at least one
(3) 0/1 (4) 1/4 intron is termed as :- [AMU 2007]
37. A pedigree is shown below for a disease that is (1) split gene
autosomal dominant. The genetic make up of the (2) operator gene
first generation is [OLYMPIAD– 2 0 0 4]
(3) synthetic gene
Generation-I (4) epistatic gene
44. Select the two correct statements out of the four
(a-d) given below about lac operon : [CBSE 2010]
Generation-II
(a) Glucose or galactose may bind with the repressor
and inactivated
Generation-III (b) In the absence of lactose the repressor binds
witht the operator region
(1) AA, Aa (2) Aa, aa
(c) The z-gene codes for permease
(3) Aa, AA (4) Aa, Aa
(d) This was elucidated by Francois Jacob and Jacque
38. At a particular locus, frequency of 'A' allele is 0·6 Monod
and that of 'a' is 0·4. What would be the frequency
The correct statements are :
of heterozygotes in a random mating population at
equilibrium – [AIPMT-2005] (1) (b) and (d) (2) (a) and (b)
(1) 0·24 (2) 0·16 (3) (b) and (c) (4) (a) and (c)
(3) 0·48 (4) 0·36 45. Which one of the following symbols and its repre-
39. One ene–one enzyme hypothesis was postulated by sentation, used in human pedigree analysis is cor-
rect? [CBSE 2010]
[AIPMT-2006]
(4) The pedigree chart is wrong as this is not possible (1) Off
Inducer on
48. A normal woman whose father was albino, marries (2) Inactive repressor + Co-repressor = active
an albino man, what proportion of normal and al- repressor
bino are expected among their offsprings :- (3) Active repressor + Inducer = inactive repressor
[AIPMT-94] (4) On Inducer
off
(1) All normal (2) 2 normal : 1 Albino 56. What does "lac" refer to, in what we call the lac
(3) All albino (4) 1 normal : 1 Albino operon :- [A I P M T– 2 0 0 3 ]
49. Albinism is determined by a recessive gene in man. (1) Lactose (2) Lactase
The presence of albinism in 50% children born to a (3) Lac insect
couple proves that :- (4) The number 1,00,000
(1) Both parents are heterozygous for albinism 57. A nutritionally wild type organism, which does not
(2) Father is homozygous normal and mother is het- require any additional growth supplement is known
erozygous as :- [A I P M T– 2 0 0 4]
(3) Father is homozygous for albinism but mother is (1) Prototroph (2) Phenotype
heterozygous (3) Holotype (4) Auxotroph
(4) Both are homozygous 58. Which of the following is not produced by E.Coli
50. In Drosophila several alleles exhibit same in the lactose operon –
phenotype for eg. W+s, W+c, W+g exhibit eye colour (1) galactosidase
these alleles are called :– (2) Thiogalactoside transacetylase
(1) Pseudoalleles (2) Isoalleles (3) Lactose dehydrogenase
(3) Multiple alleles (4) All the above (4) Lactose permease
51. In Drosophila a set of homeiotic genes which controls 59. An organism is able to live on a culture medium
body plan at the time of organ differentiation known containing nutrient A, by the enzyme catalysed
as : reactinons :–
(1) TATA-box (2) Homeobox
A B C A mutant failed to
X Y
(3) Pribnow box (4) All the above
survive on this medium but grew when nutrient B
52. Gene which is responsible for the synthesis of a was added to it. Which gene of this mutant was
polypeptide chain is called :- defective :-
(1) Promotor gene
(1) Only X
(2) Structural gene
(2) Only Y
(3) Regulator gene
(3) X and Y both
(4) Operator gene
(4) Neither X or Y
60. E. coli cells with a mutated z gene of the lac operon 67. Jumping genes are found in :- [MP PMT 2003]
cannot grow in medium containing only lactose as (1) eukaryotes (2) bacteriophage
the source of energy because – [AIPMT-2005] (3) bacteria
(1)They ca nnot synthesize functional (4) eukaryotes and prokaryotes
betagalactosidase 68. The genes that keeps on changing-their location
on chromosomes are known as :[MP PMT 2003]
(2)They cannot transport lactose from the medium
(1) Jumping genes (2) Duplicate genes
into the cell
(3) Lethal genes (4) Split genes
(3)The lac operon is constitutively active in these
69. Polydactyly in man is due to :- [MP PMT 2003]
cells
(1) autosomal dominant gene
(4)In the presence of glucose, E. coli cells do not (2) autosomal recessive gene
utilize lactose (3) sex - linked dominant gene
61. A functional complex comprising a cluster of genes (4) sex - linked recessive gene
including structural gene, a promoter gene, an 70. Blue eye colour in human is recessive to brown eye
operator gene and a regulator gene was discovered colour. The expected children of a marriage be-
by :- [Uttaranchal PMT 2006] tween a blue eyed woman and a brown eyed man
(1) Beadle and Tatum (1958) who had a blue eyed mother will be-
(1) All black eyed
(2) Watson and crick (1953)
(2) All blue eyed
(3) Jacob and Monad (1961)
(3) All brown eyed
(4) Britten and Davidson (1961) (4) One blue eyed and one brown eyed
62. Functioning of structural genes is controlled by :- 71. Nobel prize for the concept of jumping genes was
[C.G. PMT 2 005] awarded to :- [C.G. PMT 2006]
(1) H.G. khorana
(1) Operator (2) Promoter
(2) Barabara Mc clintock
(3) Ligase (4) Regulator gene
(3) Kornberg
63. Family has 9 girls, Probability of son at 10th birth (4) Watson
is :- [UP CPMT 2005]
72. DNA finger printing was invented by :–
(1) 50% (2) 100%
[ MP PMT 2007, RPMT 2011]
(3) 25% (4) 75%
(1) Kary Mullis (2) Alec Jeffery
64. Who explained the operon model for the first time
(3) Dr. Paul Berg (4) Francis Collins
(1) Francois Jacob [MP PMT 2001]
(1) cells need specific enzymes in order to function (2) Satellite DNA occurring as highly repeated short
DNA segments
(2) genes are made of DNA
(3) The relative proportions of purines and
(3) genes carry information for making proteins
pyrimidines in DNA
(4) enzymes are required to repair damaged DNA (4) The relative difference in the DNA occurence
information. in blood, skin and saliva
98. Read the following four statements (A-D):
(A) In transcription, adenosine pairs with uracil.
(B) Regulation of lac operon by repressor is referred
to as positive regulation.
(C) The human genome has approximately 50,000
genes.
(D) Haemophilia is a sex-linked recessive disease.
How many of the above statements are right?
[AIPMT (Mains) 2012]
Que. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Ans. 2 2 4 1 1 3 1 2 1 2 2 2 1 3 3 1 2 4 3 2
Que. 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
Ans. 3 4 3 4 1 1 3 3 4 4 1 2 2 3 2 1 2 3 4 2
Que. 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
Ans. 1 4 1 1 3 2 3 4 3 2 2 2 4 3 2 1 1 3 1 1
Que. 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80
Ans. 3 4 1 3 3 1 4 1 1 4 2 2 1 1 4 2 1 4 3 2
Que. 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98
Ans. 3 3 1 2 1 2 4 2 1 3 3 1 1 3 4 2 2 3
EXERCISE-5 NCERT BASED QUESTION
1. Select the incorrect statement for Gregor Mendel– 7. The phenotype of any character will not be affected
(1) He conducted hybridization experiments on if the modified allele produces–
garden pea for seven years. (1) Normal enzyme (2) Non-functional enzyme
(2) He applied statistical analysis and mathematical (3) No-enzyme at all (4) 2 and 3 both
logic for the first time to the problems in biology.
8. The three different alleles of human ABO blood
(3) His experiments had a small sampling size. types will produce how many genotypes &
(4) He conducted artificial cross-polination experiments phenotypes respectively–
using several true-breeding pea lines. (1) 4 & 6 (2) 6 & 4
2. Mendel observed that all the F1 progeny plants. (3) 6 & 6 (4) 4 & 4
(1) resembled either one of the parents 9. "When two pairs of traits are combined in a hybrid,
(2) resembled neither of the parents segregation of one pair of characters is independent
(3) resembled both of the parents of the other pair of characters". This explains–
(4) shows 3 : 1 ratio (1) Law of dominance
3. Accoding to Mendel, "factors" or "genes" (2) Law of segregation
(1) are the units of inheritance (3) Law of independent assortment
(2) contain information that is required to express (4) Postulate of paired factors
a particular trait
10. Morgan coined the term_____ to describe the
(3) Both 1 and 2 physical association of genes on a chromosome &
(4) None of the above the term_______ to describe the generation of
4. The segregration of alleles is a random process and non-parental gene combinations.
so there is a ______ chance of a gametes containing (1) Recombination; Linkage
either allele.
(2) Recombination; Non-recombination
(1) 25% (2) 50%
(3) Linkage; Non-recombination
(3) 75% (4) 100%
(4) Linkage; Recombination
5. Based on observation on monohybrid crosses Mendel
11. In which organism female in homogametic & also
draw some conclusion. Which of the following is not
have one chromosomes more than male.
correct–
(1) Birds (2) Drosophila
(1) Characters are controlled by discrete units called
factors (3) Chicks (4) Grasshopper
(2) Factors occur in pairs 12. Given below is the pedigree of an autosomal
dominant disorder-Myotonic dystrophy.
(3) In a similar pair of factors one member of the
pair dominates the other
(4) The postulate of dominance also explains the
proportion of 3 : 1 obtained at the F2
6. In the inheritance of flower colour in dog flower
plant, the F1 had a phenotype that
(1) resembles both of the parents
In this pedigree the genotype of all affected children
(2) did not resembles either of the two parents will be –
(3) resembles with only one parent (1) AA (2) Aa
(4) 1 and 3 both (3) AA or Aa (4) aa
13. Given below is the pedigree of sickle cell anaemia, 18. Other than pea plants it was found that sometimes
in a family the F1 had a phenotype that did not resemble either
of the two parents and was in between the two. It is
due to
(1) Complete Dominance
(2) Incomplete Dominance
(3) Co-Dominance
(4) Complementary gene interaction
In this the RBC of both parents will be –
19. Which of the following material is good to
(1) Normal
understand incomplete dominance
(2) Sickle shaped
(1) Sweet Pea (2) Cattle
(3) Both normal & sickle shaped
(3) Snapdrogon (4) Kernel colour in wheat
(4) Cannot be determined 20. Find out the correct match –
14. The accessibility of promotor regions of prokaryotic (1) F1 resembled either of the two parents - Dominance
DNA by RNA polymerase is in many cases regulated (2) F1 resembled in between -incomplete dominance
by the interaction of some protein with sequences (3) F1 resembled both parent - Co-dominance
termed as – (4) All are correct
(1) Promoter (2) Operator 21. Which is incorrect –
(3) Regulator (4) Cistron (i) ABO blood groups are controlled by the gene I
(ii) Gene I has four alleles
15. Which of the following is not associated with HGP–
(iii) IA and IB produce same type of sugar
(1) Bioinformatics (iv) i or I° produce different type of sugar
(2) Cloning vectors BAC & YAC (v) IA and IB are incomplete dominant
(3) Automated DNA sequencers (1) i, ii (2) v, ii
(3) ii, iii, iv (4) ii, iii, iv, v
(4) VNTR
22. Which Scientist has no role in rediscovery of
16. In density gradient centrifugation , the bulk DNA Mendel's results
forms_____ while satellite DNA forms________. (1) Vries (2) Correns
(1) Major peak; Minor peak (3) Tschermak (4) Morgan
(2) Minor peak; Major peak 23. Experimental verification of the chromosomal
theory of inheritance done by Thomas Hunt Morgan
(3) Major peak; Major peak and his colleagues they worked with –
(4) Minor peak; Minor peak (1) Pea plant (2) Sweet pea plant
17. Select the incorrect statement. (3) Snapdragon (4) Drosophila
24. Which is incorrect for Drosophila melanogaster
(1) DNA from single cell is enough to perform DNA
fingerprinting analysis (1) They could be grown on simple synthetic medium
(2) Single mating could produce a large number of
(2) DNA fingerprinting has much wider applications progeny
in determining population & genetic diversities.
(3) They complete their life cycle in about 7 weeks
(3) The VNTR belongs to a class of satellite DNA (4) There was a clear differentiation of the sexes.
referred as microsatellite. 25. Regulation of lac operon by repressor is referred
(4) DNA fingerprint differs from individual to to as–
individual in a population except in the case of (1) Positive regulation (2) Nagative regulation
monozygotic twins. (3) Both (1) and (2) (4) None
26. Which is incorrect 34. Which of the following is responsible for sex
(1) i-gene codes for the repressor of lac operon determination in chick :-
(2) z-gene codes for the beta-galactosidase (1) Sperm (2) Egg
(3) y-gene codes for transacetylase (3) Somatic cell (4) Every cell of body
(4) three gene products are required for metabolism 35. Morgan and his group found that when genes were
of lactose grouped on the same chromosome, some genes
27. Which is the primary step for regulation of gene were very tightly linked and showed–
expression.
(1) Very low recombination
(1) Transport of m-RNA from nucleus to the
cytoplasm (2) Higher recombination
(2) When the modified allele produce a non (1) XO type male in Grasshopper
functional enzyme (2) XY type male in human
(3) When the unmodified allele produce no enzyme (3) ZW male in birds
(4) All the above (4) 1 and 2 both
42. Which of the following condition is true for 47. In a cross between true red flowered (RR) and true
codominance– breeding white flowered (rr), snapdragon plant, the
(1) Phenotype of F1 resembled either of the two F1(Rr) was pink. When the F1 was self pollinated the
parents F2 resulted in the following ratio 1(RR) red; 2(Rr) pink;
1(rr) white. Above condition can be explained by–
(2) Phenotype of F1 did not resemble either of two
parents (1) True dominance
(3) Phenotype of F1 resembles both parents (2) Incomplete dominance
Que. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Ans. 3 1 3 2 3 2 1 2 3 4 4 2 3 2 4 1 3 2 3 4
Que. 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40
Ans. 4 4 4 3 2 3 4 2 3 2 1 3 1 2 1 3 3 2 1 3
Que. 41 42 43 44 45 46 47 48 49 50
Ans. 2 3 1 1 3 4 2 3 3 4