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Pathophysiology of Dengue

Hemorrhagic Fever
By Jessica Pestka, eHow Contributor
updated: February 3, 2011

Signs of dengue fever

Dengue fever, a contagious disease transmitted by the Aedes aegypti

mosquito, infects between 50 million and 100 million people worldwide
each year. Also known as breakbone or dandy fever, dengue fever is
found in the tropical and subtropical regions of the world. Exposure to the
flavivirus that causes dengue fever results in one of three
pathophysiologies: dengue fever, the more severe dengue hemorrhagic
fever (DHF) or dengue shock syndrome.

Transmission of Dengue Fever

1. Dengue fever is transmitted only through an infected mosquito or by
contact with the blood of someone who is actively infected with one
of the four viruses responsible for the fever. Infection with one of
these viruses generally provides immunity from dengue fever for as
much as a year after the illness. A small minority of cases of dengue
fever develop into severe forms of the fever, DHF or dengue shock
syndrome, which require hospitalization.
Symptoms of Dengue Fever
2. Early symptoms of dengue fever include headache, chills, backache,
fever, nausea and joint pain. The initial fever may be as high as 104
degrees Fahrenheit at the onset of the illness and individuals may
develop severe pain in the legs and behind the eyes. A rash
consisting of patchy bright red spots may develop over the body
after the first few days of illness.
Time Frame:Dengue Infection
3. After five to eight days of incubation, individuals infected with
dengue fever develop symptoms abruptly. The initial symptoms of
dengue fever last about six to seven days. The fever climbs rapidly
in the first 48 to 96 hours of the illness and then may break for a day
before elevating rapidly again. This second phase of the fever is
often when a rash may appear on the limbs or chest.
Diagnosis of Dengue Fever
4. A diagnosis of dengue fever is typically not considered unless the
individual has been in a tropical location where the virus is present
such as Central America, South America, Africa or Asia. Clinically,
individuals with dengue fever may develop a low white blood cell
count by the second day of illness. This low white blood cell count,
coupled with the "dengue triad" of fever, rash and headache,
represent the most common diagnostic criteria for dengue fever.
Prevention of Dengue Fever
5. Dengue fever can only be prevented by avoiding travel to those
tropical locations where the illness is present. If travel to tropical
regions cannot be avoided, travelers should use barrier and
chemical methods to prevent mosquito bites. Once contracted,
treatment of dengue fever generally includes rest and fever/pain
management. Total recovery from dengue fever may take several
Dengue Fever: Tropical and Subtropical Climates
6. Dengue fever is not present in the United States, although the
Centers for Disease Control reports that 100 to 200 cases of dengue
fever are brought into the United States each year. Dengue fever is
considered endemic in tropical and subtropical areas and outbreaks
have occurred in the Virgin Islands, the Caribbean and Puerto Rico.

Read more: Pathophysiology of Dengue Hemorrhagic Fever |

Give me the Pathophysiology of Dengue Fever?

Q. All Significant about the Dengue fever...The Pathophysiogic of this ifectious
Asked by jjbusaratz - Sat Oct 7 01:53:08 2006 - - 2 Answers - 1 Comments
A. The simple answer to your question is it's a virus. For more info:
Answered by Panacea - Sat Oct 7 02:03:30 2006

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pathophysiology of dengue?
Q. please please help! what's the pathophysiology of dengue hemorrhagic
Asked by rei - Mon Aug 7 09:21:32 2006 - - 3 Answers - 0 Comments

A. The principal symptoms of dengue are high fever, severe headache,

backache, joint pains, nausea and vomiting, eye pain, and rash. Generally,
younger children have a milder illness than older children and adults. Dengue
hemorrhagic fever is characterized by a fever that lasts from 2 to 7 days, with
general signs and symptoms that could occur with many other illnesses (e.g.,
nausea, vomiting, abdominal pain, and headache). This stage is followed by
hemorrhagic manifestations, tendency to bruise easily or other types of skin
hemorrhages, bleeding nose or gums, and possibly internal bleeding. The
smallest blood vessels (capillaries) become excessively permeable (a leakya ),
allowing the fluid component to escape from the blood vessels. This… [cont.]
Answered by scott i - Mon Aug 7 09:43:27 2006

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paradigm of pathophysiology of dengue hemorrhagic fever with vasculitis
Q. paradigm of pathophysiology of dengue hemorrhagic fever with vasculitis
Asked by John P - Sat Aug 9 10:14:13 2008 - - 2 Answers - 0 Comments

A. Here is everything that would need to know regarding pathophysiology of

dengue, including other diseases that cause vasculitis.
Answered by intelex - Sat Aug 9 13:39:37 2008

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pathophysiology of dengue hemorrhagic fever please..... i need it for my
case study?
Q. pathophysiology of dengue hemorrhagic fever please... i need it for my case
Asked by anne_hbo - Mon Nov 19 07:05:32 2007 - - 1 Answers - 1 Comments

A. Alternative Names -Hemorrhagic dengue; Dengue shock syndrome; Philippine

hemorrhagic fever; Thai hemorrhagic fever; Singapore hemorrhagic fever
Definition -Dengue hemorrhagic fever is a severe, potentially deadly infection
spread by certain mosquitoes (Aedes aegypti ). Causes -Four different dengue
viruses have been shown to cause dengue hemorrhagic fever. This condition
occurs when a person catches a different dengue virus after being infected by
another type sometime before. Prior immunity to a different dengue virus type
plays an important role in this severe disease. Worldwide, more than 100 million
cases of dengue fever occur every year. A small number of these develop into
dengue hemorrhagic fever. Most infections in the United… [cont.]
Answered by lizbelle_28 - Mon Nov 19 08:02:05 2007

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pathophysiology of dengue fever?
Q. pathophysiology of dengue fever?
Asked by harold s - Tue Feb 27 10:35:43 2007 - - 0 Answers - 0 Comments

A. I hope this helps: Dengue viral infections frequently are not apparent. Classic
dengue primarily occurs in nonimmune, nonindigenous adults and children.
Symptoms begin after a 5- to 10-day incubation period. DHF/DSS usually occurs
during a second dengue infection in persons with preexisting actively or passively
(maternally) acquired immunity to a heterologous dengue virus serotype. Illness
begins abruptly with a minor stage of 2-4 days' duration followed by rapid
deterioration. Increased vascular permeability, bleeding, and possible DIC may
be mediated by circulating dengue antigen-antibody complexes, activation of
complement, and release of vasoactive amines. In the process of immune
elimination of infected cells, proteases and… [cont.]
Answered by a Marie - Thu Mar 1 17:50:10 2007