Process Systems Engineering

Lisia Dias and Marianthi Ierapetritou

Department of Chemical and Biochemical Engineering, Rutgers University

Process Systems Engineering Course

Bahia Blanca, Argentina
Feb 19-21, 2019
 Course outline
Day 1
• Process control
• Scheduling
• Planning
• Supply chain
Day 2
• Integration of scheduling and control
• Integration of planning and scheduling
Day 3
• Feasibility analysis
• Black-box optimization
• Pharmaceutical manufacturing: challenges and opportunities
2
 Final Project

• Topic of your choice

• Goal is to apply concepts taught in the course

• Pair up and select a problem from your own field of research

• Final project can be purely theoretical, but use our help for

implementation!

• 10-minutes presentation at Day 3

3
 Enterprise-wide Optimization

Lisia Dias and Marianthi Ierapetritou

Department of Chemical and Biochemical Engineering, Rutgers University

Process Systems Engineering Course

Bahia Blanca, Argentina
Feb 19-21, 2019
 Enterprise-wide Optimization

• Strategic level
• Design and logistic decisions
Supply Chain • Time horizon: years

• Tactical level
• Allocation and distribution of
Planning materials
• Time horizon: months

• Operational level
• Production sequences and
Scheduling resource allocation
• Time horizon: days-weeks

• Operational level
• Setpoint tracking and
Process Control disturbance rejection
• Time horizon: min - seconds 5
 State-of-art
Paper Planning Scheduling Control
Biegler, L. T. (2018). Comp. Chem. Eng., 114, 3-13. x x
Brunaud, B., & Grossmann, I. E. (2017). Front. Eng, 4(3), 256-270. x x
Burnak, B., Katz, J., Diangelakis, N., Pistikopoulos, E. (2018). Ind Eng Chem Res, x x
57 (11), 3963-3976
Castro, P.M, Grossmann, I.E., Zhang, Q. Comp. Chem. Eng. 114, 14-42, 2018 x x
Charitopoulos, V. M., Papageorgiou, L. G., & Dua, V. (2018). Comp. Chem. Eng. x x x
Chu, Y., & You, F. (2015). Comp. Chem. Eng., 83, 2-20. x x
Daoutidis, P., Lee, J. H., Harjunkoski, I., Skogestad, S., Baldea, M., & Georgakis, C. x x
(2018). Comp. Chem. Eng., 115, 179-184.
Dias, L. S., Pattison, R. C., Tsay, C., Baldea, M., & Ierapetritou, M. G. (2018). Comp. x x
Chem. Eng., 113, 139-151.
Gutiérrez-Limón, M., Flores-Tlacuahuac, A., Grossmann, I. (2016). Comp. Chem. x x x
Eng., 84, 507-515.
Isaksson, A., Harjunkoski, I., Sand, G. (2018) Comp Chem Eng 114, 122-129. x x x
Kelley, M., Pattison, R., Baldick, R., Baldea, M. (2018). Comp. Chem. Eng., 110, 35- x x
52.
Lee, H., & Maravelias, C. T. (2017). Comp. Chem. Eng., 106, 621-644. x
Maravelias, C. T., & Sung, C. (2009). Comp. Chem. Eng., 33(12), 1919-1930. x x 6
Ning, C., & You, F. (2018). Comp. Chem. Eng., 112, 190-210. x x