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DRUG STUDY

Generic Brand Classificatio Dosage Indication Contraindicati Adverse Nursing Consideration

Name Name n on Reaction

Celecoxi Celebrex Analgesic 200mg/ * acute and long *contraindicat CNS: Assess patient¶s range
b (non opioid) cap bid term treatment ed with headaches, of motion, degree of
NSAID —
 of signs and allergies to dizziness, swelling, and pain in
Specific symptoms of sulfonamides, somnolence,affected joints before
COX-2 Initially, rheumatoid celecoxib, insomnia and periodically
enzyme 100mg
arthritis and NSAIDs, or throughout therapy.
inhibitor PO bid;
osteoarthritis aspirin; CV: MI, CVA ‡ Assess patient for
may significant allergy to
increas *reduction of the renal failure;Others: rash, sulfonamides, aspirin,
e to number pregnancy; pruritus, or NSAIDS. Patients
200mg/ colorectal lactation nausea, with these allergies
day PO polyps in familial dyspepsia, should not receive
bid as
adenomatous *use peripheral celecoxib.
needed
polyposis cautiously with edema, ‡ May be administered
.
impaired anaphylactoi without regard to
  *management of hearing, d reactions meals.
acute pain hepatic and to ‡ Instruct patient to
CV conditions anaphylactic take celecoxib exactly
10 kg *treatment for shock as directed. Do not
or 25 primary take more than
kg or dysmenorrheal prescribed dose.
less: 50 Increasing doses does
mg
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capsule *relief of not appear to increase

PO bid. symptoms of effectiveness.
More juvenile ‡ Advise patient to
than 25 rheumatoid notify health care
kg: arthritis professional promptly if
100mg signs or symptoms of
capsule GI toxicity (abdominal
PO bid. pain, black stools), skin
rash, unexplained
weight gain, edema

 occurs.
  ‡Patient should
  discontinue celecoxib
 and notify health care

 professional if signs
and symptoms of
Reduce hepatotoxicity (nausea,
dosage fatigue, lethargy,
by 50% pruritus, jaundice,
upper right quadrant
tenderness, flu-like
symptoms) occur.
Be aware that patient
may be at increased
risk for CV events, GI
bleeding, monitor
accordingly.

Administer drug with

food or after meals if
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GI upset occurs
Establish safety
measures if CNS or
visual disturbances
occur.
Arrange for periodic
ophthalmologic
examination during
long-term therapy

Take drug with food or

meals if GI upset
occurs.

Take only the

prescribed dosage, do
not increase dosage

You may experience

these side effects

Report some throat,

fever, rash, itching,
weight gain, swelling in
ankles or fingers,
changes in vision