ACTIVE LEARNING TEMPLATE: Medication

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STUDENT NAME______________________________________
Naloxone
MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER____________

CATEGORY CLASS__opioid antagonist / antidotes (for opioids)

_____________________________________________________________________

PURPOSE OF MEDICATION

Expected Pharmacological Action Therapeutic Use

Competitively blocks the effects of opioids, Reversal of signs of opiod excess.
including CNS and respiratory depression,
without producing any agonist effects.

Complications Medication Administration

Hypertension, hypotension, nausea, vomiting, ventricular Nasal spray: 4mg/0.1mL
arrythmias. Solution for injection: 0.4mg/mL,
2mg/0.4mL, 2mg/2mL, 4mg/
10mL
In Combination with:
buprenorphine (Suboxone,
Zubsol).
Contraindications/Precautions
Hypersensitivity
Contraindicated: cardiovascular disease, patients
physically dependend on opioids, may cause acute Nursing Interventions
withdrawal syndrome in neonates of opioid-dependent Monitor: RR, rhythm, and depth,
mothers. pulse, ECG, BP, LOC,
frequently for 3-4 hour after the
expected peak and blood
concentrations.
Interactions
Assess pain level after
Can precipitate withdrawal in patients physically administration of medication.
dependent on opioid analgesics. Larger doses may be
required to reverse the effects of buprenorphine,
butorphanol, or nalbuphine. Antagonizes postoperative
opioid analgesics. Client Education
Explain purpose and effects to
patient.
Evaluation of Medication Effectiveness Instranasal: instruct parents and
Adequate ventilation following opioid excess. Alertness caregiver in the correct
without significant pain or withdrawal symptoms. technique for use.
Evzio: advise to continue
monitoring patient after injection

ACTIVE LEARNING TEMPLATES