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VISION PHYSIOLOGY 1
o Embryologically derived from the - Secretes aqueous humor - Drains the aqueous humor
diencephalon; hence, a derivative of the
CNS
o The functional part covers the posterior **The aqueous humor has a constant volume meaning the
part of the eye except for the OPTIC DISC amount produced by the choroid bodies is equal to the
amount drained by the canals of Schlemm.
** Optic disc where the optic nerve axons leave the
retina GLAUCOMA when the aqueous humor is not absorbed
adequately, intraocular pressure increases which can
- No photoreceptors are found within this area
cause blindness since blood flow to the retina is impeded.
- Referred to as the “anatomic blind spot”
Refraction
Suspensory
ligaments
Relaxed ciliary become taut Flattening of lens
muscles
IRIS
SENSORY NEURONS
COORDINATOR: brain
MOTOR NEURONS
RODS VS CONES
Simply put...
The fovea is the portion of the retina which has the highest
resolution for vision because:
- It has the highest cone density
o So you can infer that an area within the
retina which has a high density of cones
will definitely have a high resolution for
vision
- The cells are pushed aside so that less layers
would have to be penetrated.
o Less layers less hindrance less
Rods and cones are not distributed equally in the retina image distortion
In the light...
When a photon of light is absorbed by the photopigment,
the conformation of rhodopsin will change. The 11-cis
retinal will become an all-trans retinal, while the opsin will
dissociate with rhodopsin. This conformational change will
then activate the G-protein transducin, that will further yield
more phosphodiesterase and subsequently destroy cGMP
leading to the closing of the Na+ channels. With the closing
of the channels, the photoreceptor area becomes
HYPERPOLARIZED. As a result, this wave of
hyperpolarization will reach the synaptic area of the rod
cells preventing the release of the neurotransmitter
glutamate. If glutamate is absent, then the bipolar cells can
PHYSIOLOGY: VISION PHYSIOLOGY 1 Page 5
now be activated. And when the bipolar cells become active, o This is due to the constant influx of Na+
it can synapse with the ganglion cells which will develop an ions brought about by the opened Na+
action potential, transmitting the image to the brain. channels.
(please refer to fig.1 for a schematic representation of 4. In the dark, Na+ ions can enter the cell since the
these processes) channel is opened. During the day, no Na+ ions can
enter since the Na+ channels are closed.
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VISUAL TRANSDUCTION
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