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AHTVIOKCMAAHTHBIE CBOMCTBA S@VUPHbIX MACEA LIBETKOBbIX PACTEHUI” M.C. Hlapanaeea, M.C. Cnupudoxosa Beenenne Ocupane Macta mpererannmor coGoH yHMKaNbHMe H XHMMYeCKOM oTHoMeHIH cmech oprammieckHx RemecTR, KTopHie MpHAawr pacrenisAM npustTHiit aanax. B cocran adbupHBIx MacesT BXONLT CIINPTH, csIOAKUBIE achUpH, KETOHEL, TAKTOML, apowa- THMeCKHe KOMIONEHTS! HT. J, OAHAKO NpeossiaAAONUNME sBLIAOTCA TepnenoMAHE coeaHHeHHA ms Homacca MoHoTepnenonsoR (sapoMaTuueckHe TepnenonAKD, dpe- nmmponaxomint ur. 1.) [Bapa6oli 1976; Cano 1975; Tecan 1995]. B nacToamwe npenst ofbupHite Maca UIMpoKO HeHOMbayWTeH B kaNeCTRe ApOMATH- aaTopoR THmenoil H KocMeTHYeckoi npoayKi. Crom XHMEIeCKHt cocTaR THX REIMECTR MOSROMACT He TOEKO MpHAARATE MpoAYKTAM MpPHATHBIT samax, HOH MposR- JMITh ANTHOKCHAHTHBIe 1s MpooKcHAantHere croiicraa. B smrrepatype mpaxrirsec- ki o1cyTeTRYIT AaNMMe 06 aNTHOKcHAANTHOM HoTeAMMAZTe adupHEIX MacesT, oT) MY ONeHKa UX MaHrnOMpyiomeit axTHRHOCTH sRAKeTeA ARTyAZTbHOIT, 910 TosBOsMHT Ha- AeHATh NPOLYKTL! 2aqaHHbIMH XUMITYecKHMN cBOiCTRAaMH. Tak, aHTHOKCH_aHTDI CHOCOOHBI He TOKO YReTFaHEATS cpoK XpaneHuA MpoxyKTOB, HO H KoppeKTHpoBaTs ‘enoGontoparmkastiste (CP) mponeccer 8 oprantame yesToneKa. B nacrosmee apema ocoSoii nony.aspHoctsw y necTenoBaTe melt nosbsyIoTeR sdpup- HIE Maca WMTPYCORBIX pacteHHit 1 xBoiHEIX MOpoz, Aeperner. OnHaKO MpuMeHa- eMble B MUMeROoii 1 KOcMeTHYeCKOii MpOMBUILIeHHOCTH pacTeHua MpeAcTaB.IeHDI B OC HORHOM TpazaMH 4 HBeTKOREIMM pacrenusam, Henb1 padorH sBIAIaCb ONeHKA al ‘THOKCHAAHTHO! AkTHBHOCTH obupHLIX Mace TAKHX HRETKOBLIX acTenmit, KAK TeOp- rau Dahlia pinnate (4a rpynnt kaxtyconnanbIx reopriuon), THIcAYEAHCTHME OOBIK- wonennssit Achillea millefolium L. (cemeitetno Asteraceae) 1 KoxioKosmanK Campa- nula Latifolia L. BsxGop 7x pacrennit ue cnyvaen. Teopram nenostbayetca B mtme- BMX HeNAX ¢ APERHHX RPeMeH, O;HAKO AAMHBIe o ETO XIMUMECKOM COCTaRe B sutTepa- ‘Type emummannt. Kpome Toro, reoprnn sBasetcs HOMy.IApHBIM HxeTKORLIM pacteHu- em cpeit caqonogon He Toso Hentpasbuoit reppuropum Poceum, Hom a Cudup- ckom 0 Jlam.HenocrouHoM peruonax. TstesuesCTHMK H KOOKOAB'IE ObITH BEIOpA- UI B eBaisHt ¢ HX MMpoKO! pacnpoctpantennocTsw n KpacHoapexom Kpac 1 HEICOKOIt TonytapHoersW aTHx pactennit B (uToTepanHt. OBvexrb! n MeTaabi MccneaoRaHNA Osnerramn Hecenonanna Onc adprpuie Macsia reoprima, ThIcAYesMHCTHHKA OObIK- HoneHHOTO Ht KOIOROMBUHKA, OKCTPAKIBEA 9PPUPHEM Macest reopriiHa, There MCTHUKA, PaGura since pu dunanconoit ntoxtepxe rpawra KITIY un. BIL Acracwera (apoexer Ne 27-06-2 (HID) 40 M.C. Wapanaeea, M.C. Cnupnacnowa KOJOKOIBHMKA TpORONJIACe AHITHIOREIM adpMpoM 10 CraHlapTHoit MeTorUKe ¢ Tloctte- AYIOuUIM BpyIesTeneM ero Hs pacrropHtens [TopowancKkas, Muxanern4 1990]. Sdmp- sible Maca, NPHTOTORIEHHBIe Ha HaOTOHMYECKOM PacTHOpe XIIOPHAA HATPUs, CTIO.TEIO- BaJUich 8 cbusnostornueckux KOHMEHTpaLUAX 0.1%; 0,01 %; 0,001 % [oaxomm, Dy- pesuy 2002). Bxyc, nser « sanax o*bupHbix Mace onpesiesisumcb oprasosermirieckit. AnTHOKcHAaHTHad akTUBHOCTS ocupHBIx Macest HBeTKOBBIX pacteHuit Mayyastach MeTOJOM XeMHOMHHeCeHTHOTO anastusa 10 Tono-Oka e. a. (1983) 8 Moqunkaunn ¢ Hcrloms0Kannem paspaGorasnoro » CKTB «Hayxa» CO PAH copniitioro mporpast- MHo-atinaparypHoro KOMILZIeKca, paGoTaromlero B Pere cHeTA (bOTOHOR Ht 1OAROd SOI|ENO Haya KMNETHKY OKUCIMTETKHBIX PeAKHMH, PAaRMRAWMLAXCH HO BANS eM oksoreHHOi CTHMY:EIN KETO KpORH war B ee orcyTerEHe [BapaGaii 1976; Semexox u ap. 1987} B kavecrse nerowHmka cBoSoqUDIX pagukasion GhuIAa HCHOMEsORAHA Moe (baro- UMTHpyOWEX jeiikounTOR KpoBn YesoBeka. J\mTebHOcTL galucH KHHeTHKH MUL-peaxnun cocranssata 90 wuz. Ha ocnone stoi Mogesm uaydasmt antHoKenman- TAY! akTHBHOCTS ocbupHBX Macest, AMHoKcHaHTHBIt HoTeNIMAN sdupHEI Macest (9. m) wayyacn ¢ noon sTOcomMOit Moslem MeToz0M ¢hoTooIeKTpoKo.1opuMeT- puposanna (9K) [Baasumpos w xp. 1991]. Usa ororo roronrm simnocomny HIeHSINO CMENMIBaHMeM BHICyINeNHOTO %e/TTKA OAHOTO KypuHOTO stitta © pacrRopoM xsopiiaa Harpur (0,85 %). Tlonysennyw cycnexnsmo nenrpicbyrupowasit 30 Muna pH 2000 oG/aun. OSpasonannetit cynepuaranr pasGanssvin pacTRopoM XJOpILLa HATpUA Ao HOyYeHA ONTTHYeCKO! MIOTHOCTH cyeHeHMH, paBKol 0,96 MPH JIMHe HOHE 460 um. Jia vayveuMA aBTMOKCHAAHTHOH aKTHEHOCTH coaxanasmM “ocMoTHMecKHit erpece ¢ noMomusw 24. pacrsopa cepHoit xuenoTst. Kourpomsisie nokasanua nos “ann ¢ ucnos30RaHHeM npuGopa OOK c 7oGazaenuem cbuspacraopa BMecto abup- ner maces, AnTHOKCHTANTHaA akTHBHOCTS 9. M. ONeHIBaZaCH 10 cTeHeHH gaMente- HHA Mpontecea PaspyilenMs sHNTOCOMHO! Moe NPM BREACH ETO B PeAakTMOHAYD cect. Cramucrieckn peaysmrarsr o6paGaTsmarn ¢ HOMOLIEK MpHO:eHHi mpor- pammai Statistica 6,0 [1OuKepor, puropser 2002] Peaynsratel n nx o6cyxaeHne Odupuoe Macao reoprmma (Dahlia pinnate) weer wecrroii uper, rpansmncto- caaKnit sanax 1 cnagkonatnit mpupkyc. B saBHcHMocrH or KOMTeHTpaHM mperia- par okasniRant paamranoe jleficrane Ha ocmoTHYeCKyI cToiKOCTS ZTHTOCOMHOIL cy’ nenann (pie. 1). ‘Tax, nox 7eficranest 9. M. reopruna n KoMMeRTpamnH 0,01 % mponexosss10 s0CTO- RepHoe yervienme paspymtenua -nmocom. B KonueHTparmn 0,001 % o70 acbuptioe Macs1o 06s1aat0 JOCTORePHBIM AHTHOKCHAAHTHEIM 7elfcTRMeM, Mpexoxpartsst sHT0- Compr oT paspyilleHsia B Xoe OcMOTHYecKOTO crpecea. OcbupHoe Macsio reopruna B KonyeHTparmm 0,1 % He oKaabIBANO JOCTORepHOTO RAMAN Ha OcMOTHMECKYIO CTOII OCT -tHmOcoM. Taxoe zelicrane 9. M. reopruna moxHo oOBACHHTE aibextom pasdanzennst, B pe- aysIbrate KoTOporo ROAPACTAeT CTeNeHH /HCCONMAIUIN GOTBIINHCTRA PACTHOPIMEIS B Rolle opranmdecknx RemllecTD (CHMpTOR, OpraHM¥eckHX KHCAIOT H MHp.), CHIeNOBATE-TBHO, nospacraeT KoMM¥eCTRO GHOMOTHUeCKH ARTHRHBIX JTHTARIOR, CHOCOOHEIX, RaatMortelt- crRoRaTS ¢ penlerropaMHt KaeTosHOH MemOpanm charommtor [[logkosiams, Pypenmy 41 BectHik KPTY um. 6.9, Acracbbesa. 2007 (2) 2002}. Hooromy Gumonambunii odberr msnna'>. m. reoprina obyenopsien wasn NHeM B PACTROPe MPOOKcMAAHTOR NpH KoHMeHTpALHH 0,01% m AHTHOKeHAANTOR B Konnexrpanun 0,001 %, ccleqouaTeTEHO, eT MoxkHO HeHOstsoBATE B KAveCTRE apo- MaTHaHpyloMlero KOMMOHeHTa ¢ sa,aNHBIMI XUMHYECKHMH CBOfeTRAME. em Koinpone 0.1% reoprw = = = 0.01% reopens 0 001% reopen Puc. 1. Bauanue 9. a. 2eopeuna passunoit Konuenmpayuu Ha ocmomuveckyio emoiixocme cyenensuu aunocom (n = 10) Pesyaeramer XJl-anacmsa noxmmepswin NaRHEIe, HosVYeHHBIe Ha ZUMOCOMHOI Mose am (pune. 2). Tox zeftcrsnem acbuproro Maca reopriia B KoHMeHTpanAN 0,1 % He mpoxe- XOJUIO TOCTOREPHLIX HaMeHeHutil 110 cpaBHeHino c KoHTponem. B Konnermpannm 0.01% 9. M. Teopria OKasKIBaLIO JOCToRepHoe NpooKeMarTHoe zeiicraue. Maxemannoit ax- THOKCIANTHON aKTHBHOCTEIO OGzANAO xdbApHOe Macio Teoria R KoHNerpanm 0,001 %, xpome toro, n ero npucytermamn yponeHb HapaGorKH CP cxmxaren 70 cpennecra- ‘Tmacraseckoti HopMn (*p <0,05; **p<0,01 (tio KontposteM t-xprrrepust Crntortesra)), ‘e Hop eKorpone 10.1% reopen 90.01% reoprint | Boor cn Pa fo Hoowe Kovrpom 01% 001% e.c01% reopri reopoetreopri ax (i) Puc. 2, Bausnue 3... eeopeuna pazumott konuenmpayun na yposens napacomiu CP 42 M.. LWlapanaesa, M.C. Cnvpnachora Tax o6pasom, Momo aakMOGHTS, WTO adMpHoe sacst0 reopruna oBna-laer n030- sasncHMun yelicroueM, npueM B npesetax ¢bHanos1OTHYCCKNX KoMNeHTpaNItit Hab- shoAIOTeR BapHAIUNT TOTO AeHICTBRA OT AHTHOKCHAANTHOTO 10 MPOOKCIELAHTHOND. Scupuoe mac xonoKombauKa (Campanula Latifolia L) umeer Gemepwit user, JIMMEHHDIit BLIpAKEHHOTO BKYCA ¢ BLIPAKEHADIM UBETONHLIM apoMaToM. B aapricn- MOCTH OT KOHYeHTpaNAH 9, M. OKasbInAsIO pasH4noe JelicTRHe Ha OcMOTHYeCKyWO crofixoers summocosioti sosezi (pusc.3). B xowrpone WuMenenue onruveckoil torHocTn He MaGsONamoeb, TOMA KaK UpucyTeTBuM sdbupHoTO acta KOIOKOABNHKA B KOULEHTpANLM 0,01 % KponexomHTO JocToRepHoe paspyileHie sANNOCOM B teYeRe 5 sm. TakuM OGpasoM, oxpupHoe Mac 40 KONOKOMBUNKA B KOHTeHTpanun 0,01 % oKaziBaso IpooKcHmaHTHoe zelicrBne. Ocbmpnoe macno KonOKOSIBAHKA & KORTERTpans 0,001 % n wenDmedt crenem, wes B Konmmentpanm 0,01 %, mporonmporato paspymeHne smMOcoM, OAHAKO 970 cBILTe- ‘TesTbeTRYeT 06 OTeyTeTANN aamiTHOrO slefierRHst . af. Ha cTHITIOCOME. ee eee Eeehoth, Speen Onrmecran nnotwocTs oz 5 10 15 20 28 90 35 40 45 50 55 60 Puc. 3. Brunnue 9. .m. KonoKonuuKa pasauunoit KoMueHmpant a oeMomuMecKyIo CmoiiKOCMD cyeneNsUu JTWUNOCOM OthMpHoe macno Ko-lOKOMMBYIIKA B MAKCHMa THOM KoHMeHTpanuTH 0,1 % He oKAaBI- aslo AOcTORepHOTO RAISE Ha OCMOTHYECKYIO cToiiKOCTS sminocoM. Moxens caronmmpyiomux KqeToK KpoRm okagasack Gonee uyncreHTesEHoi K RoaelicrEmw0 scpHpHOrO Macy1a KOOKOsIBYMHKA (puc.4) Hopue tsxowrpore 150,1% sonoronsavn 0.01% sonovaneumc 0.001% ronoronsne 3000 + Puc, 4, Bauanue 9. m. Konowonvuuna pasmunol RonyeHmpanut ha ypoeen napasonnu CP BecTHnk KITV mm. 8.0. Actadbeaa. 2007 (2) Tox aeiicrauem acpupHoro Macta KoNOKOTPUNKAa B KOHTIeHTpanHn 0,1 u 0,01 % Tpouexosu0 AoctoRepHoe cHPKeHMe TmKa XJI-peaKNM MO cpapHEHM0 ¢ KORTpO- eM, TOna KAK B KONMEHTpaIUH 0,001 % ocTORepHOTO seficTBUA OHO He OKAsbIBAZO. Takum o6paaom, 9. M. KoOKObUNKa obmadaer HHTHOHpy!Mlelt AKTHBHOCTEI, KOTO- pas npostisiack noaansenm XII p MaKeHMastsuo¥ ero KoMMeHTpannt (0,1 %). B Konmentpanim 0,01% abupnoe macci0 KoNOKorBHNKA ORAIHIBATO AO-neiicrane, upnvem crmxenne XJI-peaxmim mpoucxoxu10 R mpenesax cpeanecratucrusteckoii nopaat, Cnexonatesibno, nenomsays adbmpHoe Maco KOsIOKOTBUNKA R_MaKCHMA,TE- Hoi M cpeaHeii KOHMeHTpaH, MOAHO UPUAABATS MpOLYKTY aWTHoKcHgaHTHDIe cpoitcrra, Oehupuioe Macno TnesHemerunKa Achillea millefolium L (comeiierno Asteraceae) akesTTO-3eneHOTO MBeTA ¢ TepHKHM BKyCOM. B ganHeHMOCTH OF KOHUeHTpaNsH OHO OKashIRAaTO pasMyHOe AelicrBHe Ha OCMOTHYeCKYW CTOMKOCTL JMNOCOMHOTT MOZesTH (pune. 5). Oe Korrpore 0.1% Taenverwerne = = 01% rwcmvenwvernn 0.00184 raomerer o7 06s. 08 055 05 0045 04 035 03 025 02 FEET EL pew (us) 123456789 On Puc, 5. Bauanue 3... motcavenucmuura pasnunnoi Konuenmpayun a emomueckyio cmotixocmb cycnenaum stunocar Stbmproe macso Thet4eTHeTHHKA B KOHUCHTpAUME 0,1 % 1 0,01 % He oB.taa;t0 AOCTOREpHO! aHTHOKeHAANTHOIE HM MpoOKCHAAHTHO! axKriAHocTHD, B KoHNeNTpa- un 0,001 % 9. M. TbIcAYesTHCTHHKa OKAsbIBAaIO HHTHOMpyimee AeftcTBHe, samensAT mpontece paspymenust sm1n10c0M. PesyasTaTst XeMIsOMUNeCHeHTHOFO AHAIHaA odpupHoro Maca TeIcaesNCTHHKA npencrassiensi na pue. 6. Tox neficranem 9. M, THCsMeMICTHMKA & KOHTIENTpALUH 0,01% He mpowcxogHs0 qocronepHEIX MIMeHeHHI M0 cpaRHeHmo c KoNTpOseM, Seupnoe macno vueHemcrunKa B KONMeHTParNT 0,001 % oKAaHas mpooKeH- JANTHOe AeficrHHe, BLIpAKaloMeecs MpAKTHMeCKH B TPEXKPATHOM ycusIeHNH ypoBHA renepamm AOK darowrramn, AnTHoKeranTHoii axTmBHocrsio obras.asio adpupHoe Macro ThIeaue/ICTHHKA B KoHMeHTpanus 0,1 %, Kpome Toro, B ero NpHcyTerBuM ypo- nem Hapadorku CP pesko cumpxacics, 410 cBMeTeIECTRYeT 0 Gosbmoit 4yBCTBUTE NIL HOCTH atMpHOrO Maca TRICHYESINCTINKA K YecIORHSIM HpOReAEHUA XHMEECKO! pe- axnun. 44 M.C. LWapanaega, MLC, Cnupnaonoea em aia som mae, ae aon 5 3 seco Z 200 7 7 ‘00 oF | yy Heows —Fowtpoms.H4 20% 001% Puc. 6. Bawanue 9. 4. moicavemicmnura pasawinon Konuenmpayue a yposen» wapadomxu CP OehnpHoe Maco Thica¥eAMCTAIKA XapaKTepMayercs GHMONA:THOCTHIO XIMIECKO- ro oberra: Mp MaKenMasbHOit KOHUEHTpAUNH oH MposRaeT nurHOMpyromee aelicrane, a B MUNUMarmHOit — MpooKcnzanTHoe. Takum oGpasom, ace HecwreqoRanmre adbupubte Maca xapakrepHgonastich Gimto- AAsMHOCTHIO, KOTOPO MPOABSIOCh B PAIHBIX KONUCHTPANASX, sHO R ANTHOKCHAN- THoii, aH60 B npooKcHyanTHoii axTuBHoctn. CreqoRaTerbHO, acpHpHble Mac.1a, B OT- JNIHE PACTHTEBHBIX IKCTPAKTOR, MOFYT HCHODJORATHEH A OMIpes{eTIeHHOM KOHILEH- "PALM KAK AHTHOKCHAAHTH LHX UPOOKCHAAHTHDL, MpH¥eM slOCTHraTbes OxIUIA- emntit odxbexr Gyaer npaxtuseckn w 100% eny4aen, Budnuocepagureckuit cnucor 1. Bapa6oli, B.A. Buonorueckoe aelicrene pacturenniar cbenomsunix coeximennit | B.A. BapaGoit, ~ Kuen: Haywora JIywna, 1976. —C. 8-30. 2. Baasmmmpon, 10.A. CroSoxume parunasit n aux cneneax 1O.A. Baaamsumon, O.A. Asaona, ATT, Jleen, A.B, Koasosa, AH. Ocunon, J). Pomyuxun /f Wrorn nayxi ‘rexamxnt —(Cep. «Broduomxay). —T. 29. — 1991. -C. 67-72. 8. Topoancxas, 9.7, Bnostormueckoe zefierane mpmpommx arroxcnanron 9.0. Topo- axanckas, 0.1], Muxasenns // Kummeckas srramunosiorus, — 1990, —C. 25-26. 4, Semexon, BM. Haysenne dbynsnuonatsuoro eocTosun dbarommron westoneKa (xre.10p0; notit metaGommam 1 nogBibkHocre KorerTox) / B.M. Semexor, A.A. Bapcyxou, C.A. Beswo- cenxo, —M.: Huermryr mmyronora M3 CCCP, 1987, - 18 c. 6, Kanmuxuna, PM, Xmvoreckit cocran acrpiiix Macex Hexoropiix nrgjon ThicavenmerHna quopm CuGupi / TH. Kanuskana, AJL. NemGungnit /) Ximena pacrirestsi0ro cepa. 2000. —C. 13-18. 6. Tlonxo-rann, A.A. Jleiiernne Siotornveckm axrHanirx nemgern m Matix qosax / A.A, Tloa- xosaun, K.P. 'ypesia.—M.: KMK, 2002. ~ 170 c. BectHnk KITTY wm. 6.9. Acadbesa. 2007 (2) Canto, BM, Sesrensce apyana “estonena /B.M. Cano. ~M.: HayKa, 1975, ~ 272 e. ‘Teco, JLC. Cparmuressnoe mayuerme chaaRonommuoTo cocrara sion poxa Campanula L, Pana Glomeratae charadze us cegusm Campanula / JI.C. Tecaor // Pactirrestsuuie pe~ cypest, ~ 1995, —No 1.—C, 44-52. JOnxepon, BH. Matemaruxo-crarneruvexan oGpaGorka slamithX MeaBUAHOKIN HecTeAOEA- mii! BH, Onnepon, CI. Tpnropres.— C16: Vaz-no Boenno-mermmumcroli axazewa, 2002. -267«