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1. Minute opening of the tubular structure playing an important role in germination of seeds is
a) Arillode b) Caruncle c) Micropyle d) Hilum
7. During Nitric acid test of aloe, color obtained was Brownish-green. variety of aloe is
a) Zanzibar b) Cape c) Curacao d) Socotrine
11. All microscopical statements are true for “Rattlesnake root” except
a) starch grains are present b) absence of phloem fibres
c) medullary rays are lignified d) presence of diarch primary xylem
12. Vanillin shows all IR peaks (cm-1) in the region below, except one
a) 1050-1150 (COR stretch) b) 1720 (C=O stretch) c) 3650 (OH stretch) d) 1650 (NH bend)
13. A test that differentiate between pale catechu & black catechu is
a) vanillin & Hydrochloric acid gives Pinkish red color
b) green fluorescence with petroleum ether & ethanolic sodium hydroxide
c) reddish brown fluorescence with chloroform
d) Brownish red color with ferric chloride.
14. Chief active constituent present in Anethum graveolens is
a) Fenchone b) carvone c) anethole d) cineole
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18. In Jalap, Convolvulin on hydrolysis yields rhamnoconvolvulic acid, exogenic acid &
a) atropine b) abietic acid c) tiglic acid d) umbellic acid
22. Artemisinin is a sesquiterpene lactone from Artemisia annua, should contain active constituent
not less than
a) 0.75 % b) 1 % c) 0.1% d) 0.05 %
25. Murexide test is done for the presence of caffine, uses potassium chlorate & Hydrochloric acid
treatment with the drug gives characterstic
a) yellow color b) purple color c) purple ppt d) green ppt
26. During friability studies, tablets are supposed to be best that lose weight less than
a) 1.3 % b) 0.5-1 % c) 5 % d) 2-3 %
27. Find the sparingly soluble category of 1 mg drug tested for its solubility
a) 100-1000 ml b) 10-30 ml c) 30-100 ml d) more than 1000 ml
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31. All Ranges of Tablet efficiency of a sugar coated tablet are acceptable except one
a) 61 % b) 57 % c) 67 % d) 73 %
32. Kaolin, cocoa powder are used in one step of tablet sugar coating
a) seal coating b) syrup coating c) sub coating d) polishing
33. A problem of tablet coating that can be relieved by replacing low melting point substances with
higher melting point substances is
a) orange peel effect b) lamination c) blistering d) picking
34. Hard gelatin capsule size possessing lesser volume (ml) is of size
a) 00 b) 0 c) 2 d) 5
37. All equations best suits to Fisher subsieve sizer for surface area determination except
a) BET equation b) Poiseuille’s equation c) stokes equation d) kozeny carman equation
39. Find the deflocculated sedimentation volume of paracetamol suspension in water. initial volume
was 100 ml, final volume was find to be 44 ml (degree of flocculation is 1.5)
a) 2.9 b) 1.2 c) 0.90 d) 0.29
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c) Nitroglycerine sublingual tablet d) Di sodium cromoglycate soft gelatin capsule
45. 500 mg Paracetamol was given to a patient. First order elimination rate constant is 10 and
clearance is 50 ml/min. Find the plasma drug concentration.
a) 10 mg b) 50 mg c) 100 mg d) 5 mg
55. A graph between current and active ions in solution (ml) keeping voltage constant is plotted in
a) polarography b) conductometery c) amperometery d) potentiometry
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a) x-rays b) radiowave c) microwave d) gamma rays
61. In interference filter, high dielectric constant films are suspended between two parallel rodes,
these rodes are made up of
a) gold b) silver c) Silicon oxide d) calcium fluoride
63. Find the lambda max value for the compound given below
CH2
64. Find the lambda max value for the compound given below
Cl C CH3
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CH3 O
H2 C
O CH3
a) 4 b) 2 c) 3 4) 5
74. Spraying agent used for the detection of lipids in chromatographic plate is
a) diphenyl hydrazine b) bromocresol green c) bromophenol blue d) aniline phthalate
75. Gradient technique is the technique of elution that includes
a) changing adsorbent for different substances b) changing solvent composition
c) keeping solvent system same throughout the process d) rising evaporating temperature
76. Technique used to improve the process of separation by the column/detector in gas
chromatography is done by
a) derivitisation by treatment with tetramethyl silane (TMS)
b) making the component more volatile
c) increasing active sites on solid support
d) decreasing the thickness/amount of liquid film on solid support
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79. Beta carbolines are the
a) partial agonist of benzodiazepines b) pure agonist of benzodiazepines
c) pure antagonist of benzodiazepines d) inverse agonist of benzodiazepines
82. Phenylepherine is an
a) α1 agonist b) β1 agonist c) α1 antagonist d) α2 agonist
83. Bretylium
a) prevent the release of NA from nerve endings b) displaces NA from nerve endings
c) stimulates the release of NA from nerve endings d) reduces the formation of NA
84. Ondansetron is
a) 5-HT agonist b) 5-HT antagonist c) AT1 agonist d) H1 antagonist
93. Wilson’s disease is caused due to the abnormal metabolism of an ion in body
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a) copper b) cobalt c) mercury d) iron
94. The starting materials required for the synthesis of chlorphinramine are
a) 4-chlorobenzylcyanide & 2-bromopyridine b) 2-chlorobenzylcyanide & 4-bromopyridine
c) 4-chloropyridine & 2-bromobenzylcyanide d) 2-chloropyridine & 4-bromobenzylcyanide
98. The drug act by inhibiting an enzyme DNA dependent RNA polymerase is
a) cephalaxin b) novobioscin c) ofloxacilin d) rifabutin
103. Mifepristone is
a) estrogen antagonist b) estrogen agonist c) progesterone agonist d) progesterone antagonist
106. 3,20-dione,11β,17α-hydroxy,6α-flouro,16α-methyl is
a) Paramethasone b) dexametasone c) Prednisolone d) Corticosterone
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107. An ultra short acting barbiturate is
a) pentobarbital b) butabarbital c) Phenobarbital d) hexobarbitone
114. All statements regarding the SAR of benzodiazepines are correct except one, identify
R3 O
N CH2
2
A B
5 4
7 N
C
R1
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115. An anticancer agent act by causing defected microtubules polymerization due to essential
protein consumption inhibition is
a) topotecan b) paclitaxal c) vincristine d) etoposide
116. About the correct answer of above question one thing is true, identify
a) inhibits topoisomerase 1 b) inhibits topoisomerase 2
b) possesses cruciferous stomata d) is a diterpenoid
122. An ester of veratric acid (3,4-dimethoxy benzoic acid) relaxing smooth muscles is
a) papaverine b) mebeverine c) tubocurarine d) dantrolene
127. Angiotensin 3 is a
a) heptapeptide b) nonapeptide c) decapeptide d) octapeptide
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128. Find the odd one
a) phenindiones b) enoxapoarin c) protamine sulphate d) dicoumarol
133. The starting materials required for the synthesis of chlorambucil are
a) P-aminophenylbutyric acid & ethylene oxide
b) P-aminophenylbenzoic acid & methylene oxide
c) P-aminophenylbenzoic acid & ethylene oxide
d) P-aminobenzylphenolic acid & ethylene oxide
136. A schedule describing factory premises for ayurvedic drugs comes under
a) T b) U c) Q d) FF
139. Application for wholesale of drugs under category C, C1 but not in X is applied in
a) 20 B b) 21 B c) 21 BB d) 20 BB
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a) alanine b) valine c) glycine d) tryptophan
150. Measles vaccine is tested for checking freedom from neuro virulance on
a) ox b) monkey c) horse d) pig
151. Roye’s sachet is used for the chemical validation of sterilization technique
a) dry heat b) moist heat c) gaseous d) radiation
152. Microbe used for the biological validation of moist heat sterilization is
a) Clostridium sporugenes b) Bacillus pumulis
c) Pseudomonas dimnuta d) Serratia mercesense
154. The number of degree of temperature change to produce a ten fold change in D-value is called
a) F-value b) lethal value c) Z-value d) R-value
156. Pyrogens can be effectively expelled out from a parentral solution by methods
a) Dry heat at 250’c for 30 min b) Passing through membrane filter
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c) Reverse osmosis d) All above
157. Maximum bubble pressure test is done for checking the efficiency of
a) parentrals b) aerosols c) HEPA filter d) membrane filter
160. A solution was shaken with high stress, soon it converted to thick gel. The solution was
a) Pseudoplastic b) Plastic c) Dilatent d) Newtonian
162. Match the following data of angle of repose & flow properties
1. Less than 25 a) very poor
2. 25-30 b) passable
3. 30-40 c) good
4. More than 40 d) excellent
a) 1-d, 2-c, 3-b, 4-a b) 1-a, 2-b, 3-c, 4-d c) 1-c, 2-d, 3-b, 4-a d) 1-b, 2-d, 3-c, 4-a
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4. Surface diameter d) ostward viscometer
a) 1-d, 2-c, 3-a, 4-b b) 1-d, 2-b, 3-c, 4-a c) 1-d, 2-b, 3-a, 4-c d) 1-d, 2-c, 3-b, 4-a
176. Heparin
a) inhibits antithrombin 3 b) activates antithrombin 3
c) inhibits vitamin k epoxide reductase d) activates vitamin k epoxide reductase
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180. The value of Geminal coupling (Hz) ranges from
a) 0-15 b) 1-18 c) 5-18 d) 0-20
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OH
OH
CHO
NaOH
CHCl3
196. Find the odd one that is not the isoster of rest 3 options.
a) NH b) CH2 c) O d) CH3
OCOC6H5
OH
NaOH HCl
C6H5COCl
199. Lysuride is
a) D1 agonist b) D2 agonist c) D1, D2 agonist d) antagonist of both
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ANSWERS
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