Riosa, Desiree Mae L.

Group 5

Drug Mechanism of Administrati Indication Contraindicati Adverse Nsg.

Name Action on on Effect Responsibilities

MIdazolam Classification: Dosage:  Preprocedural Hypersensitiv Rarely  Assess level

Anti-anxiety IV: inject 2.5 sedation. ity to cardioresp of sedation
agents, mg for 2 benzodiazepi adverse and level of
 Aids in the
sedative/hypno minutes nes. Chronic events, consciousne
tics induction of respiratory nausea, ss
(never as
bolus) anesthesia insufficiency. vomiting, throughout
Action: and as part of headache, and for 2-6
IM: 0.07-
Physiologic balanced hiccoughs, hr following
0.08 mg/kg
Mechanism laryngospas administrati
anesthesia
m, on.
• Short-term
Route: dyspnoea,  Monitor BP,
sedation hallucination pulse and
IM, IV
• Postoperative , respiration
amnesia oversedation continuously
Pharmacologic , drowsiness, during IV
Mechanism ataxia, rash, administrati
paradoxical on. Oxygen
• Acts at many
reactions, and
levels of the amnesic resuscitative
CNS to produce episodes. equipment
generalized should be
CNS immediately
depression. available.
 If overdose
• Effects may
occurs,
be mediated monitor
by GABA, an pulse,
inhibitory respiration ,
neurotransmitt and BP
continuously
Riosa, Desiree Mae L.
Group 5

er. . Maintain
patent
airway and
assist ventil
ation as
needed. If
hypotension
occurs,
treatment
includes IV
fluids,
repositionin
g and
vasopressor
s.
 The effects
of
midazolam
can be
reversed
with
flumazenil
(Romazicon)
.