mum (h-1) 0.

10074761
Ks (g/L) 4.28388331
Yxs (g/g) 0.40344796

Tiempo (h) X (g/L) S (g/L)

0 1.5 48.5

xi1  xi  t * f ( xi , si )
8 2.9 45.2
15 5.5 38.8
23 11.4 24 1
27 16.3 11.8
30 19.2 4.5

Δt
34 20.9

0.5
0.3
si1  si  t * f ( xi , si ) 2

Modelo Experimental
Tiempo (h) X (g/L) S (g/L) mu (h-1) qs (h-1) F1 F2 X (g/L)
0 1.5 48.5 0.09257104 0.22944977 0.13885656 -0.34417465 1.5
0.5 1.56942828 48.3279127 0.0925443 0.22938348 0.14524164 -0.36000092
1 1.6420491 48.1479122 0.09251613 0.22931367 0.15191604 -0.37654431
1.5 1.71800712 47.9596401 0.09248647 0.22924015 0.15889241 -0.3938362
2 1.79745332 47.762722 0.09245521 0.22916268 0.16618393 -0.41190921
2.5 1.88054529 47.5567674 0.09242227 0.22908102 0.17380426 -0.43079723
3 1.96744742 47.3413687 0.09238753 0.22899492 0.18176762 -0.45053546
3.5 2.05833123 47.116101 0.09235089 0.2289041 0.19008873 -0.47116047
4 2.1533756 46.8805208 0.09231223 0.22880828 0.19878291 -0.49271016
4.5 2.25276705 46.6341657 0.09227142 0.22870712 0.20786602 -0.51522386
5 2.35670006 46.3765538 0.09222832 0.22860028 0.21735448 -0.5387423
5.5 2.4653773 46.1071826 0.09218278 0.2284874 0.22726533 -0.56330766
6 2.57900996 45.8255288 0.09213464 0.22836808 0.23761615 -0.58896355
6.5 2.69781803 45.531047 0.09208372 0.22824188 0.24842512 -0.61575506
7 2.8220306 45.2231695 0.09202984 0.22810833 0.25971103 -0.64372869
7.5 2.95188611 44.9013051 0.09197279 0.22796693 0.27149321 -0.67293241
8 3.08763271 44.5648389 0.09191235 0.22781712 0.28379159 -0.70341559 2.9
8.5 3.22952851 44.2131311 0.09184828 0.2276583 0.29662663 -0.73522897
9 3.37784182 43.8455167 0.0917803 0.22748982 0.31001935 -0.76842463
9.5 3.5328515 43.4613043 0.09170814 0.22731096 0.32399125 -0.80305586
10 3.69484712 43.0597764 0.09163148 0.22712093 0.3385643 -0.83917713
10.5 3.86412928 42.6401878 0.09154996 0.22691889 0.35376089 -0.87684392
11 4.04100972 42.2017659 0.09146322 0.22670388 0.36960375 -0.91611257
11.5 4.2258116 41.7437096 0.09137082 0.22647486 0.38611587 -0.95704009
12 4.41886953 41.2651896 0.09127231 0.22623069 0.40332044 -0.99968392
12.5 4.62052975 40.7653476 0.09116718 0.22597011 0.42124066 -1.0441016
13 4.83115009 40.2432968 0.09105486 0.2256917 0.43989967 -1.09035046
13.5 5.05109992 39.6981216 0.09093471 0.2253939 0.4593203 -1.13848711
 14 5.28076007 39.128878 0.09080604 0.22507497 0.47952491 -1.18856693
14.5 5.52052253 38.5345945 0.09066806 0.22473297 0.50053506 -1.24064342
15 5.77079006 37.9142728 0.09051989 0.22436571 0.52237127 -1.29476739 5.5
15.5 6.03197569 37.2668891 0.09036053 0.22397073 0.54505254 -1.35098599
16 6.30450196 36.5913961 0.09018888 0.22354526 0.56859597 -1.40934154
16.5 6.58879995 35.8867254 0.09000366 0.22308617 0.59301611 -1.46987012
17 6.885308 35.1517903 0.08980343 0.22258988 0.61832429 -1.53259985
17.5 7.19447015 34.3854904 0.08958655 0.22205232 0.64452779 -1.59754876
18 7.51673404 33.586716 0.08935114 0.22146882 0.67162878 -1.6647222
18.5 7.85254843 32.7543549 0.08909503 0.22083401 0.69962304 -1.73410973
19 8.20235995 31.8873 0.08881571 0.22014167 0.7284984 -1.8056812
19.5 8.56660915 30.9844594 0.08851026 0.21938458 0.75823281 -1.87938193
20 8.94572555 30.0447685 0.08817528 0.21855429 0.78879188 -1.9551267
20.5 9.3401215 29.0672051 0.08780677 0.21764089 0.82012592 -2.03279232
21 9.75018446 28.050809 0.08739999 0.21663263 0.85216607 -2.11220814
21.5 10.1762675 26.9947049 0.08694932 0.21551558 0.88481954 -2.19314415
22 10.6186773 25.8981328 0.086448 0.21427299 0.91796342 -2.27529572
22.5 11.077659 24.760485 0.0858879 0.21288469 0.95143681 -2.35826402
23 11.5533774 23.5813529 0.0852591 0.21132614 0.98503054 -2.44153059 11.4
23.5 12.0458927 22.3605876 0.08454946 0.20956721 1.01847377 -2.52442413
24 12.5551295 21.0983756 0.08374396 0.20757066 1.05141628 -2.60607656
24.5 13.0808377 19.7953373 0.08282381 0.20528996 1.08340488 -2.6853646
25 13.6225401 18.452655 0.08176534 0.20266639 1.11385168 -2.76083109
25.5 14.179466 17.0722395 0.08053837 0.19962517 1.14199107 -2.83057836
26 14.7504615 15.6569503 0.07910403 0.19606997 1.16682096 -2.89212256
26.5 15.333872 14.210889 0.07741177 0.19187548 1.1870222 -2.94219405
27 15.9273831 12.739792 0.07539521 0.18687716 1.2008484 -2.97646416 16.3
27.5 16.5278073 11.2515599 0.07296655 0.18085741 1.20597715 -2.98917644
28 17.1307958 9.75697167 0.07000938 0.17352766 1.19931642 -2.97266693
28.5 17.730454 8.2706382 0.06637027 0.16450764 1.17677508 -2.91679521
29 18.3188416 6.8122406 0.06185195 0.15330838 1.13305616 -2.80843198
29.5 18.8853697 5.40802461 0.05621654 0.13934026 1.06167018 -2.63149223
30 19.4162048 4.09227849 0.0492215 0.12200211 0.95569478 -2.36881797 19.2
30.5 19.8940521 2.90786951 0.04073567 0.10096884 0.81039763 -2.00867945
31 20.299251 1.90352978 0.03099455 0.07682415 0.62916612 -1.55947278
31.5 20.613834 1.12379339 0.02093681 0.0518947 0.43158792 -1.06974866
32 20.829628 0.58891906 0.01217619 0.03018033 0.25362559 -0.62864512
32.5 20.9564408 0.2745965 0.0060689 0.01504257 0.12718246 -0.31523883
33 21.020032 0.11697708 0.00267792 0.00663759 0.05629001 -0.13952235
33.5 21.048177 0.04721591 0.00109831 0.00272231 0.02311742 -0.05729964
34 21.0597357 0.01856609 0.00043475 0.00107759 0.00915571 -0.02269367 20.9
 60

50

40

Biomasa exp

( xi , si )
30 Sustrato exp
Biomasa modelo
1 20
Sustrato modelo

( xi , si )
10

0
0 5 10 15 20 25 30 35 40

Experimental
S (g/L) (Dif X)^2 (Dif S)^2
48.5 0 0

45.2 0.03520604 0.40342958

38.8 0.07332725 0.78451262

24 0.02352462 0.17526536

11.8 0.13884338 0.88320895

4.5 0.0467445 0.16623683

0.3 0.0255155 0.07920505

0.34316129 2.49185838 2.83501968
um 0.2733
Xm 10.58
alfa 4.80044683

xi1  xi 
beta 0.00061362
Y0xs 0.10275064
m 0

Tiempo (h) Biomasa

(X), g/L
Glucosa
(S), g/L
Etanol (P),
g/L
si1  si  
0 0.5 100 0
2 1 95 2.5
5 2.1 85 7.5
10 4.8 58 20
15 7.7 30 34
20 9.6 12 43
25 10.4 5 47.5
30 10.7 2 49

h 0.5

Modelo
Tiempo (h) X (g/L) S (g/L) P (g/L) mu qs qp Yp/s
0 0.5 100 0 0.26038412 2.53413633 1.25057375 0.49349111
0.5 0.56509603 99.3664659 0.31264344 0.25870258 2.51777103 1.24250158 0.49349268
1 0.63819193 98.6550747 0.66370979 0.25681438 2.49939454 1.2334374 0.49349448
1.5 0.72014036 97.857528 1.05729469 0.25469751 2.47879251 1.22327547 0.49349652
2 0.81184934 96.9649887 1.49775971 0.2523285 2.45573665 1.21190319 0.49349884
2.5 0.9142757 95.9681446 1.98970112 0.24968265 2.42998642 1.19920191 0.49350149
3 1.0284151 94.8573059 2.5379017 0.24673423 2.4012915 1.18504818 0.49350451
3.5 1.1552877 93.6225437 3.14726242 0.24345689 2.36939542 1.16931547 0.49350795
4 1.29591907 92.253877 3.82271031 0.23982413 2.33404035 1.15187662 0.49351187
4.5 1.45131541 90.7415133 4.56907975 0.23580997 2.29497334 1.13260685 0.49351634
5 1.62243273 89.0761482 5.39096464 0.23138971 2.25195403 1.11138762 0.49352145
5.5 1.81013985 87.2493262 6.29254046 0.22654091 2.20476401 1.08811119 0.49352728
6 2.01517521 85.2538606 7.27735718 0.22124448 2.15321762 1.06268599 0.49353395
6.5 2.23809841 83.0843052 8.34810642 0.21548598 2.09717419 1.03504263 0.49354156
7 2.47923782 80.7374641 9.50637005 0.20925693 2.03655116 1.00514038 0.49355027
7.5 2.73863667 78.2129168 10.7523611 0.2025562 1.97133767 0.97297389 0.49356024
8 3.01600059 75.513528 12.0846721 0.1953914 1.90160771 0.93857966 0.49357165
8.5 3.31065088 72.645903 13.5000505 0.18778007 1.82753191 0.90204185 0.49358473
9 3.621488 69.6207429 14.9932233 0.1797506 1.74938671 0.86349681 0.49359973
9.5 3.94697032 66.4530514 16.556795 0.17134282 1.66755967 0.82313571 0.49361694
10 4.28511283 63.1621472 18.1812411 0.162608 1.58254983 0.78120469 0.49363671
10.5 4.63350965 59.7714449 19.8550162 0.1536083 1.49496203 0.7380021 0.49365943
 11 4.98938242 56.3079844 21.5647861 0.14441548 1.40549475 0.69387246 0.49368556
11.5 5.34965445 52.801709 23.2957836 0.13510902 1.31492149 0.64919729 0.49371563
12 5.71104774 49.2845212 25.0322742 0.1257736 1.22406635 0.60438309 0.49375027
12.5 6.07019724 45.7891705 26.7581046 0.11649613 1.1337753 0.55984712 0.49379019
13 6.4237745 42.3480507 28.4572958 0.10736261 1.04488512 0.51600213 0.49383623
13.5 6.7686111 38.9919975 30.1146365 0.09845488 0.95819237 0.47324102 0.49388936
14 7.10181248 35.7491817 31.7162287 0.0898477 0.87442474 0.43192272 0.49395071
14.5 7.42085324 32.6441815 33.2499457 0.08160631 0.79421712 0.3923604 0.49402158
15 7.72364748 29.6972971 34.7057702 0.07378461 0.71809392 0.35481271 0.49410348
15.5 8.00859063 26.924145 36.0759943 0.06642402 0.64645852 0.31947862 0.49419817
16 8.27457204 24.3355341 37.3552811 0.05955326 0.57959015 0.28649587 0.49430769
16.5 8.5209609 21.9376039 38.5405964 0.0531886 0.5176474 0.25594267 0.49443437
17 8.74756989 19.7321773 39.6310352 0.04733489 0.46067735 0.22784225 0.49458097
17.5 8.95460252 17.7172736 40.6275682 0.04198687 0.40862885 0.20216938 0.49475063
18 9.14259041 15.8877191 41.5327414 0.03713082 0.36136824 0.17885813 0.49494702
18.5 9.31232633 14.2357982 42.3503547 0.03274624 0.31869622 0.1578102 0.49517438
19 9.46479817 12.7518966 43.0851448 0.02880762 0.28036443 0.13890309 0.49543763
19.5 9.60112734 11.4251003 43.7424897 0.025286 0.24609095 0.12199773 0.49574245
20 9.7225144 10.243725 44.3281475 0.02215036 0.21557395 0.10694525 0.49609543
20.5 9.830193 9.19576456 44.8480359 0.01936883 0.18850329 0.09359268 0.4965042
21 9.92539268 8.26925271 45.3080529 0.01690966 0.16456986 0.08178754 0.49697761
21.5 10.0093102 7.45254247 45.7139396 0.01474192 0.1434728 0.07138143 0.49752589
22 10.0830884 6.7345106 46.0711791 0.0128361 0.12492477 0.06223264 0.4981609
22.5 10.1478022 6.10469683 46.3849277 0.01116443 0.10865558 0.05420787 0.49889638
23 10.2044494 5.55338919 46.6599731 0.00970113 0.09441433 0.04718339 0.49974822
23.5 10.2539467 5.07166606 46.9007133 0.00842253 0.08197057 0.04104552 0.50073486
24 10.2971288 4.65140511 47.1111526 0.00730706 0.0711145 0.03569077 0.50187762
24.5 10.3347497 4.28526754 47.2949089 0.00633525 0.06165652 0.03102564 0.50320124
25 10.3674863 3.9666652 47.45523 0.0054896 0.05342646 0.02696617 0.50473434
25.5 10.395943 3.68971615 47.5950157 0.00475452 0.04627238 0.02343743 0.50651007
26 10.4206568 3.44919365 47.7168428 0.00411611 0.04005926 0.02037281 0.50856684
26.5 10.4421031 3.24047174 47.8229918 0.00356212 0.03466761 0.01771338 0.51094914
27 10.4607011 3.05947038 47.9154743 0.0030817 0.02999202 0.01540716 0.51370849
27.5 10.4768195 2.90260159 47.9960591 0.00266533 0.02593983 0.01340842 0.51690458
28 10.4907816 2.76671815 48.0662979 0.00230467 0.02242972 0.01167706 0.52060654
28.5 10.5028705 2.64906551 48.1275486 0.00199239 0.01939054 0.01017799 0.52489442
29 10.5133334 2.54723733 48.1809977 0.00172212 0.01676014 0.00888055 0.52986098
29.5 10.522386 2.45913484 48.2276797 0.00148827 0.0144843 0.00775799 0.53561363
30 10.5302161 2.38293014 48.268496 0.00128601 0.0125158 0.00678703 0.5422768

120

100

80
120

100

80

60

40

20

0
0 5 10 15 20
xi1  xi  t * f ( xi , si ) 1

si1  si  t * f ( xi , si ) 2

Experimental
F1 F2 F3 X (g/L) S (g/L) P (g/L) (Dif X)^2 (Dif S)^2
0.13019206 -1.26706816 0.62528688 0.5 100 0 0 0
0.1461918 -1.42278241 0.70213271
0.16389687 -1.59509343 0.7871698
0.18341796 -1.78507854 0.88093004
0.20485273 -1.99368818 0.98388281 1 95 2.5 0.03540067 3.86118071
0.22827878 -2.22167754 1.09640118
0.25374521 -2.46952443 1.21872143
0.28126275 -2.73733338 1.35089578
0.31079267 -3.02472741 1.49273888
0.34223464 -3.33073016 1.64376978
0.37541424 -3.65364392 1.80315166 2.1 85 7.5 0.2280705 16.614984
0.41007072 -3.99093119 1.96963343
0.44584639 -4.33911077 2.14149847
0.48227884 -4.69368222 2.31652726
0.51879769 -5.04909467 2.49198205
0.55472784 -5.39877762 2.66462198
0.58930059 -5.73524997 2.83075681
0.62167425 -6.05032014 2.98634566
0.65096463 -6.33538299 3.12714335
0.67628502 -6.58180853 3.24889221
0.69679364 -6.78140457 3.34755025 4.8 58 20 0.2651088 26.6477634
0.71174554 -6.92692097 3.41953985
0.72054406 -7.01255081 3.46199505
0.72278657 -7.03437562 3.47298119
0.71829902 -6.99070136 3.45166066
0.70715451 -6.88223968 3.39838243
0.68967321 -6.7121064 3.31468133
0.66640277 -6.4856315 3.20318442
0.63808151 -6.21000051 3.06743418
0.60558849 -5.89376869 2.91164893
0.5698863 -5.54630428 2.74044827 7.7 30 34 0.0005592 0.09162904
0.53196282 -5.17722166 2.5585735
0.49277772 -4.79586048 2.3706307
0.45321798 -4.41085326 2.18087747
0.41406527 -4.02980734 1.99306602
0.37597577 -3.65910892 1.81034645
0.33947185 -3.30384181 1.63522667
0.30494367 -2.9678032 1.46958012
0.27265835 -2.65359277 1.31468971
0.24277412 -2.36275054 1.17131574
0.2153572 -2.09592083 1.03977674 9.6 12 43 0.01500978 3.08450195
0.19039937 -1.85302372 0.92003406
0.16783499 -1.63342048 0.81177341
0.14755646 -1.43606374 0.7144789
0.12942753 -1.25962753 0.62749719
0.11329442 -1.10261529 0.55009077
0.09899472 -0.96344625 0.48148055
0.08636416 -0.84052191 0.42087862
0.07524174 -0.73227512 0.3675125
0.06547319 -0.63720469 0.32064219
0.05691338 -0.55389809 0.27957139 10.4 5 47.5 0.00105714 1.06778081
0.04942768 -0.48104502 0.24365414
0.04289262 -0.4174438 0.21229807
0.03719601 -0.36200272 0.18496498
0.03223674 -0.31373759 0.16116966
0.02792422 -0.27176688 0.14047755
0.02417777 -0.23530528 0.12250146
0.02092582 -0.20365637 0.10689809
0.01810517 -0.17620497 0.09336414
0.01566016 -0.1524094 0.08163255
0.01354192 -0.13179407 0.07146887 10.7 2 49 0.02882658 0.14663549
0.57403267 51.5144754

120

100

80
 120

100

80

60

40

20

0
15 20 25 30 35
(Dif P)^2
0

1.00448559

4.44803017

3.30788402
 0.4981116

1.76397585

0.00200435

0.53509808
11.5595897 63.6480977