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id1=10&id2=3 &id4=2
ATOR TAB.
Composition
Each tablet contains:
Atorvastatin (as atorvastatin calcium) 10 mg
Indications
As an adjunct to diet for the reduction of elevated total cholesterol, LDL-cholesterol, apolipoprotein B, and triglycerides in
cases of primary hypercholesterolaemia, combined hyperlipidaemia and heterozygous and homozygous familial
hypercholesterolaemia when response to diet and other pharmacological means are inadequate.
Precautions
Hypercholesterolaemia should be tried to be controlled with appropriate diet, exercise and weight reduction in obese
patients and treating other underlying medical problems before beginning therapy with ATOR.
ATOR may cause elevation of creatine phosphokinase and transaminase levels.
Liver function tests should be performed before beginning therapy with ATOR and periodically thereafter.
Patients having any unexplained muscle aching or muscle weakness in conjunction with increase in creatine phosphokinase
values especially if it is accompanied with malaise or fever, must consult the physician.
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Drug Interactions
Concurrent administration of cyclosporine, fibric acid derivatives, erythromycin, niacin, azole antifungals or
immunosuppressive drugs with ATOR may raise the risk of myopathy.
ATOR if co-administered with oral antacid suspension containing magnesium and aluminium hydroxides may decrease
ATOR concentrations in plasma.
Colestipol when co-administered with ATOR may result in a greater lipid-reducing effect than when either drug is taken
alone.
Concurrent administration of ATOR and digoxin increases steady - state plasma digoxin concentrations, thus the digoxin
dose should be monitored appropriately.
Co-administration of erythromycin with ATOR causes a higher plasma concentration of ATOR.
The concomitant administration of oral contraceptives (containing norethindrone and ethinyl estradiol) and ATOR causes
increased AUC values for norethindrone and ethinyl estradiol.
Contra_indications
Hypersensitivity to the drug.
Active liver disease.
Pregnancy or breast-feeding.
Side effects
The side effects of ATOR are mild, transient, few or rare and they include constipation, flatulence, dyspepsia, abdominal
pain, headache, nausea, myalgia, asthenia, diarrhoea, insomnia, angioneurotic oedema, muscle cramps, myositis,
myopathy, parasthesia, peripheral neuropathy, pancreatitis, anorexia, vomiting, alopecia, pruritus, rash, impotence,
hyperglycaemia or hypoglycaemia.
Presentation
Box of 1 strip of 7 tablets.
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