CSIR-UGC NET Questions PAPER I June 2006

1. Oxidative phosphorylation occurs in (A) Cytoplasm (B) nucleus (C) inner mitochondrial space (D) ER 2. If f(x) =x+1/x+2, f[f(1/3)] is equals to (A) 4/7 (B) 11/18 (C) 16/49 (D) 121/324 3 3 3. x-y=1, x, y are real number, then least possible value of x -y is (A) 0 (B) 1 (C) -1/4 (D) 1/4 4. In square ABCD, midpoints of AB & BC are U & V. Sine of angle UCV is A U B V C D (A) 2/5 (B) 2/10 (C) 2/5 (D) 3/5 5. External source of frequency w, Reactance Xc & inductance XL have following property (A) Xc & XL O as w (B) Xc O , XL as w (C) Xc , XL O as w (D) Xc , XL as w 6.

18
8cm

A B Find AB=? (A) 24 (B) 25 (C) 28 (D) 21 7. During apoptosis which is released by the cells (A) bax (B) apaf-1 (C) caspase (D) fad 8. If gene is the functional unit of DNA then following sequence are not possible (A) AAAAA (B) CCGCCGCCG (C) TATATATATA (D) UUUUUUUU 9. Gaseous hormone

(A) Ethylene (B) Auxin (C) Gibberellin (D) ABA 10. Inactivation of mammalian X chromosome is done by (A) Phosphorylation (B) Methylation (C) Adenylation (D) Acetylation 11. Upon illumination, chloroplast generates a gradient across their thylakoid membrane. This gradient is of (A) H+ (B) Na+/H+ (C) Cl (D) Ca+ 12. The committed step in cholesterol biosynthesis is (A) Generation of Aceto Acetyl CoA (B) Generation of mavonyl CoA by HMG CoA reductase (C) Carboxylation of acetyl CoA to form malonyl CoA by acetyle CoA carboxylase (D) Generation of crotonyl-ACP by enoyl ACP reductase 13. Semi conservative nature of DNA replication is proved by (A) G-banding (B) 35S (C) Insitu hybridization (D) BrdU (Bromodeoxouridine) 14. Gases diffuse in bulky plant tissue through (A) Apoplast (B) Symplast (C) Tracheids (D) Plasmodesmata 15. Gap junction consist of (A) Two identical connexin (B) Connexon (C) Cadhrin (D) Selectin 16. Secondary immune response is generated by (A) T cells (B) B cells (C) Naive T cell \(D) Memory cells 17. A weight m2 is kept on the table and a weight m1 is attached on the other end through a pulley. What will be acceleration of m2 & m1 M (A) m1 / m2 + m1 g m1 / m2 + m1 g (B) m2 / m1 + m2 g m1 / m1 + m2 g (C) m1 / m1 + m2 g m1 / m1 + m2 g (D) m2 / m1 + m2 g m1 / m1 + m2 g 18. If a point source S forms 5 images. What is the angle subtended by the mirror
2

M1

 /2 /2 (A) 60 (B) 120 (C) 180 (D) 360 19. Let Q be the anti particle of P, then (A) 1 of them has a +ve charge and other is ve charge. (B) Both have same mass (C) Both show Paulis exclusion principle (D) Move in opposite direction. 20. If N is an ideal gas at 127o C. Calculate the number of moles of N in a container of vol. 320 cm3 at 1 atmospheric pressure (A) 2.5 x 10-7 (B) 2.5 x 10-2 (C) 2.5 x 10-1 (D) 2.5 x 10-5 21. Thallium chloride has a shape of cesium chloride. What is the co ordination number? (A) 4 and 6 (B) 6 and 6 (C) 8 and 8 (D) 4 and 2 22. Which is computer operating system? (A) C, Java, Pascal, ADA (B ) Unix, Linux, Windows, Mac OS (C) Fortran, Oracle, Linux, Unix (D) Windows, C, C++, Java 23. Bond angle of cyclopropane, cyclobutane, cyclopentane (A) 60, 90, 109.5 (B) 60, 90, 108 (C) 90, 60, 108 (D) 108, 90, 60 24. Genes in different species that evolved from a common ancestral gene by speciation are known as (A) Orthologs (B) Analogs (C) Homologs (D) Paralogs 25. If bacteria is stored at (a) 4-9o C (b) 0o C (c) -190o C , arrange in decreasing order of their viability

(B) c, b, a (C) b, a, c (D) c, a, b 26. A group of interbreeding individuals is called (A) Sub species (B) Sibling species (C) biological species (D) Keystone species 27. Toxic algal blooms are due to (A) Diatoms (B) Green algae (C) Cynobacteria (D) Dinoflagellates 28. Arachidonic acid breakdown producing acetyl CoA involves how many cycles? (A) 10 (B) 9 (A) a, b, c (C) 8 (D) 12 29. How will we recognize hot spots in an area? (A) Endemism in plant species (B) species diversity index (C) Species richness (D) endangered species 30. diversity is present within (A) One ecosystem (B) Different ecosystem (C) Given space (D) Geographical area 31. Numerical taxonomy application (A) Characterization of species (B) It brings objectivity in taxonomy (C) Nomenclature in taxonomy (D) Identification of type species 32. In brown Pelicans and Bald eagles bioaccumulation of DDT led to (A) Thinning of egg shells ( B) CaCo3 formation (C) Decline in egg formation in females (D) no effect 33. In receptor mediated endocytosis - which of the following is involved (A) Clatherin coated pits (B) Simple pits (C) Simple vesicles (D) Hechtian strands 34. What is the function of aldosterone?

(A) Electrolyte and H2O balance (B) Ca++ and phosphate ion transport (C) Na and K transport (D) H+ gradient 35. If plasmid replication resembles chromosome replication, what will happen? (A) Plasmid replicates earlier than chromosome (B) Chromosome replicates earlier than plasmid (C) Both will replicate at same time (D) Depends on which has high G: C ratio 36. Temporary reduction in gene frequency occurs due to(A) Migration (B) bottleneck effect (C) Genetic drift (D) Speciation 37. Hardy Weinberg equation is mainly based on (A) Allele frequency (B) Genotype frequency (C) Gene frequency (D) Bottle neck effect 38. Frequency of alkaptonurea which is recessive is1in 10000. Find the frequency of heterozygous carriers in the population (A) 2% (B) 0.2% (C) 0.02% (D) 20% 39. What do you mean by Geographic isolation (A) Allopatric (B) Sympatric (C) Parapatric (D) Iteropatric 40. Which Biome shows the following characteristics - annual rain fall 150-300 cm and temperature 5o to 20oC (A) Tiaga (B) Temperate deciduous (C) Temperate evergreen (D) Grassland 41. Which of the following will not conduct electricity? (A) Sodium trifolate (B) C6H12O6 (C) CH3COOH (D) NaOH 42. A large number of ice bergs (made of fresh water) are present in the sea. When all the icebergs melt what will happen to the sea level? (A) Large increase in sea level (B) Small increase in sea level (C)No reduction in sea level (D) Large decrease in volume 43. Increasing order of concentration in sea?

(A) Argon, O2, N2 (B) CH4, Co, NH3 (C) N2, O2, Argon (D) CO2, Argon, O2 44. 5 carbon units common between Chlorophyll, Vitamin A, Vitamin K are (A) Isoprene (B) Guanido group (C) phenyl group (D) pentose ring 45. Hb, chlorophyll and cytochrome share (A) Fe (B) Porphyrin (C) Mg (D) Phytol 46. mRNA sequence reads "AAAAAAAAAAAAAAAAAAAAAAAA.AGG".On carboxypeptidase treatment, arginine is obtained. That means the direction of translation is (A) 5' to 3' (B) 3' to 5' (C) 5' to 3' only at pH 7.2 (D) 5' to 3' at pH 6.2 47. Dioscorea gives (A) Diosgenin (B) Glitoxin (C) Digitoxin (D) Digitalis 48. A bacterium divides after 5 minutes. So starting with 4 bacteria, number of bacteria after 20 minutes will be (A) 64 (B) 32 (C) 102 (D) 10 49. Binding of O2 with hemoglobin increases when (A) PO2 (B) P CO2 (C) P O2 (D) P CO2 50. According to recent information, life originated in (A) Shallow coastal water (B) Shallow inland lakes (C) Hydrothermal vents (D) Meteroites 51. Identical but reproductively isolated species are (A) Sibling species (B) Transient (C) Morphological (D) Super 52. In a field about 12% of primary production goes to herbivores, and in aquatic community about 99% of primary production goes to herbivores (A) Primary productivity of aquatic ecosystem is higher than terrestrial ecosystem (B) Primary productivity of aquatic ecosystem is lower than terrestrial ecosystem (C) Assimilatory efficiency of terrestrial herbivores is higher (D) Assimilatory efficiency of aquatic herbivores is higher 53. Maximum number of species are of

(A) Amphibians (4780) (B) Reptiles (7150) (C) Aves (9700) (D) Mammals (4650) (E) Fish (27000) 54. Which one of the following is not a characteristic of r-selected population (A) Large age at maturity (B) Early age at maturity (C) Small size (D) Large clutch size 55. Stenohaline organisms are those which (A) Can tolerate narrow range of temperature (B) Can tolerate broad range of temperature (C) Can tolerate narrow range of salinity (D) Can tolerate broad range of salinity 56. Mast cells have receptors for (A) IgE (B) IgA (C) IgB (D) IgB 57. In Albinism, what is not synthesized in the eyes (A) Rod cells (B) Cone cells (C) Melanin (D) Creatine 58. Some Bacteria are resistant to penicillin. The mechanism behind this is (A) Bacteria has an enzyme to degrade penicillin (B) Efflux (C) Glycosyl bonding (D) Restriction endonuclease 59. 9:7 ratio is found in (A) Codominance (B) incomplete dominance (C) Epistasis (D) Differential penetrance 60. Feacal contamination is checked by detecting which microorganism (A) E.Coli (B) Salmonella (C) Clostridum (D) Vibrio 61. In certain bacteria expression of some traits is controlled by population density. This is called (A) Quorum sensing (B) Population regulation (C) Diauxic growth (D) Exponential 62. Positive exponential graph will be formed between (A) Intrinsic growth rate and body size (B) Body size and generation time (C) r and generation time (D) Longivity and intrinsic growth rate 63. Which of these survivorship curves is shown by pelagic fishes

 1 3 2 4 (A) 1 (B) 2 (C) 3 (D) 4 64. The appearance of similar characteristics at different time periods in an evolution is called (A) Coevolution (B) Parallel evolution (C) Convergent evolution (D) Iterative 65. In BOD oxygen utilization curve will be represented by

A B C D 66. The ratio of daughter: parent in a radioactive compound is 3:1.If half life of the element is 10 million years. What is the age of the rock? (A) 10 million years (B) 20 million years (C) 30 million years (D) 40 million years

67. Genotype of B blood group is (A) IBi (B) IAIB (C) ii (D) IAIB 68. The graph shows

(A)Competitive inhibition (B) cooperative (C)Data is insufficient (D) Ramchandran plot 69. In C. elegans introduction of a part of x chromosome in male leads to change of sex. This means that mechanism of sex determination in C.elegans is (A) X/A ratio (B) A/X ratio (C) Hyperactivation of X chromosome (D) Inactivation of X chromosome 70. Some plants can sequester heavy metal ions. The mechanism behind this is (A) Cation efflux protein (B) Chloride channels (C) Histone binding proteins (D) Na/K pump 71. The appearance of different life forms from a common ancestor is called (A) Adaptive radiation (B ) Convergent evolution (C) Parallel evolution (D) Geographical isolation 72. RNA dependent DNA polymerase is used in the first step in which of the following viruses? (A) Epstein Barr virus (B) Hepatitis C (C) Hepatitis B (D) Human papilloma virus

1 2 3 4 5 6 7 8 9 1 0

C 1 1 B 1 2 B 1 3 B 1 4 B 1 5 A 1 6 C 1 7 D 1 8 A 1 9 B 2 0

A 2 1 B 2 2 D 2 3 A 2 4 B 2 5 D 2 6 C 2 7 A 2 8 A 2 9 B 3 0

C 3 1 B 3 2 B 3 3 A 3 4 A 3 5 C 3 6 D 3 7 B 3 8 C 3 9 B 4 0

B 4 1 A 4 2 A 4 3 A 4 4 A 4 5 A 4 6 A 4 7 A 4 8 A 4 9 C 5 0

B 5 1 C 5 2 C 5 3 A 5 4 B 5 5 A 5 6 A 5 7 A 5 8 A 5 9 A 6 0

A 6 1 D 6 2 E 6 3 A 6 4 A 6 5 A 6 6 C 6 7 A 6 8 C 6 9 A 7 0

A 7 1 B 7 2 D D C B A B A B

A C

CSIR-UGC NET Questions PAPER II June 2006 1. (a) What is scientific method? (b) Why distilled water has 6-PH? (c) A DNA molecule has 100bp added in 5ml of water. Calculate its concentration in mm. If molecular wt for an average nucleotide is 300 Dalton. (d) Calculate the height of human body is y = height, x = age; equation is y = mx+c; m= 6.2, x = 15, c=40 (a) Give the botanical name and family of following (1) Crocus (2) Coir (3) Flax (4) Vanilla (5) Saffron (b) How development of embryo in cruciferie differs from asteroid type? (c) Vavilov centre of origin of (1) Radish (2) Sesame (3) Peanut (4) Olive (a) Why virulence is lost on sub culturing.

2.

3.

(b) What are all the other mechanism apart from nitrogen fixation by which micro-organisms help the plant to obtain nitrogen. (c) In which form plants take sulphur. How is it chemically metabolized so that it becomes part of amino acids? 4. (a) Differentiate between 1 transcript and mature m-RNA. Give processing of 1 transcript. (b) What is the importance of non-coding region in post- transcriptional changes. 5. (a) Why ovulation does not occur during pregnancy? (b) Glucose is filtered through Glomerulus in Bowmans Capsule. Then why it is not excreted through urine. (c) Why in terrestrial organisms mode of excretion is through urea or uric acid but not through ammonia although former is energy consuming process. 6. (a) Differentiate between Acoelom & pseudocoelom. Give the example of each. (b) What is coelom? Differentiate between proteostome and deuterostome. 7. (a) What is water potential? Give its equation and explain. (b) Describe the events occurring in the two cell when one is placed in hypotonic solution and another is placed in hypertonic solution. 8. (a) Write various defence mechanisms bacteria use to evade host specific Immune response. (b) Difference between Immune response to Extra cellular pathogens and Intracellular pathogens. 9. (a) Picogram of a plasmid DNA was used to transform E.coli by electroporation and 700 colonies were obtained. Calculate transformation frequency of the competent cells of E.coli used in experiment. (b) A certain strain of E.coli could not be infected by many lambda phages tested. Give at least 2 possible reasons for this. (c) I wish to clone a repetitive sequence of DNA into a plasmid vector. What mutation in the E.coli genome would ensure successful maintenance of this DNA sequence in E.Coli. 10. (a) A researcher wishes to increase sucrose biosynthesis in plants through genetic engineering. Suggest a method. (b) What strategies can be used to engineer plants to produce biodegradable plastics? (c) What are the four segments of DNA that typically comprise the plasmid genome. 11. (a) Differentiate asymmetric hybrids and Cybrids. (b) Differentiate Gametoclonal variation and Somaclonal variation. (c) Differentiate electro fusion and electroportion. (d) Differentiate Androgenic and Gynogenic haploids.

12.

(a) What is the major difference between endo cytic and extracellular receptor? (b) Hydrophilic and hydrophobic signaling molecules (c) What are 2nd messengers? Name 5 in Eukaryotic signal transduction? 13. (a) Define resolution of microscope. (b) Name the organism from which green fluorescence protein was originally discovered. (c) Fluorescence ionphone. 14. (a) A student accidently mixed 2 solutions to form a new solution containing 2 proteins of similar densities ( = 1.3 gm/cc) but different mol.weight ( 60KD & 190 KD) It also contained 2 types of sub cellular organelles not very different in size but differing in densities (=1.11 gm/cc and = 1.23 gm/cc respectively). Assuming that student has access only to ultra centrifugation. What purification scheme should be planned to separate the four. (b) How will you find out if the 2 proteins are linked to each other by disulphide bridges using any technique that you know. 15. Why do cyanobacteria dominate over green alagae in eutrophic aquatic ecosystem. There is algal bloom in pond (coastal region). If piscivorus fishes are introduced, how is algal bloom in control. Explain mechanism and ecological process. 16.

. . . . .

 (S) (a) Fill in the blanks (b) What are the similarities and differences between abzymes and ribozymes ? E1

(c)

Glucose 6(P) Fructose 6-P

E2 A student hypothesizes that 2 different enzymes E1 and E2 regulate these reactions in a cell. Is it possible ? 17. (a) The phosphorylation of glucose always takes place in the presence of ATP. Why is it so? In liver cell, the concentration of glucose is 5mM each. What do you think will happen in absence of ATP under these conditions? (b) Why most of the biological reactions are kept away from equilibrium? (a) The inactivation of x chromosomes in mammals is random. Design an experiment to show this?

18.

a. b.

(b) Retinoblastosis is caused due to mutation in both the alleles of rb gene. Can this tumor be prevented if concentration of the tumor suppressor gene is increased in all the human cells. (c) Influenza virus has a cell surface protein that is activated by acidic pH and helps in fusion of influenza virus membrane with last cell membrane for virus entry into the cell. A primitive treatment to this infection involves sleeping in the horse stable. Now it has been shown that horse stable has high concentration of NH3.Diagrammatically explain this phenomenon 19. (a) Intensive shrimp culture will effect the coastal ecosystem of India. Explain. (b) Different zones in marine ecosystem. 20. (a) Citric acid cycle does not involve the utilization of O2, but TCA does not take place in the absence of O2. Why is it so? (b) Enoyl CoA isomerase deficiency will effect which metabolism? Butter or olive oil metabolism? (c) How is GTP synthesized in TCA converted to cellular pool of ATP? 21. (a) In an E.coli strain, a mutation in E lac repressor has taken place as a result of which lactose is not able to bind to the repressor. If this mutant and a wild type E.coli are grown in a medium containing lactose and glucose, What will be the growth curves of both these strains? (b) A mutant phage is not able to lysogenise in E.coli. Where would you map the mutations? What are base analogs? How are they useful in Gene mapping Gene mutations 22. (a) How would you determine RNA concentration? Give 3 methods. Which is the most sensitive method?