Академический Документы
Профессиональный Документы
Культура Документы
3. Mizuochi, T., U. Yamashita, T. Hamaoka, and K. Moriwaki: The role of Ia antigen in the
activation of T cells by concanavalin A: An evidence for the species restriction between T cells
and accessory cells. Cellular Immunology 57:28-41, 1981.
4. Kohmo, T., H. Yamamoto, T. Mizuochi, and T. Hamaoka: Detection of the dominant expression
of the TEPC-15 idiotypic determinant(s) on phosphorylcholine-specific suppressor T
lymphocytes in vitro. Journal of Immunology 126:1378-1381, 1981.
6. Takai, Y., T. Mizuochi, H. Fujiwara, and T. Hamaoka: Effects of hapten epitope structure and
hapten-self conjugation pattern of T cell specificity and Ir gene control in hapten-self cytotoxic
and helper T cell responses. Journal of Immunology 132:57-62, 1984.
10. Mizuochi T., S. Ono, T. R. Malek, and A. Singer: Characterization of two distinct primary T
cell populations that secrete interleukin-2 upon recognition of class I or class II major
histocompatibility antigens. Journal of Experimental Medicine 163:603-619, 1986.
11. Rosenberg, A. S., T. Mizuochi, and A. Singer: Analysis of T-cell subsets in rejection of Kb
mutant skin allografts differing at class I MHC. Nature 322:829-831, 1986.
1
14. Tsuchida, T., M. Takemura, J. H. Qian, Y. Izumi, T. Mizuochi, R. Maekawa, H. Fujiwara, and T.
Hamaoka: Suppressive effect of ultraviolet-B-irradiation of epidermal cells on the induction of
contact sensitivity. Microbiology and Immunology 30:65-74, 1986.
15. Singer, A., T. Mizuochi, T. I. Munitz, and R. E. Gress: Role of self antigens in the selection of
the developing T cell repertoire. In Progress in Immunology 6:60-66, 1986.
18. Rosenberg, A. S., T. Mizuochi, S. O. Sharrow, and A. Singer: Pheotype, specificity, and
function of T cell subsets and T cell interactions involved in skin allograft rejection.
Journal of Experimental Medicine 165:1296-1315, 1987.
20. Mizuochi, T., and A. Singer: Intrathymic differentiation and tolerance induction of lymphokine
secreting Lyt-2+ T helper cells. Journal of Immunology 140:1421-1424, 1988.
21. Rosenberg, A. S., T. Mizuochi, and A. Singer: Evidence for involvement of dual-function T
cells in rejection of MHC class I disparate skin grafts. Assessment of MHC class I
alloantigens as in vivo helper determinants. Journal of Experimental Medicine 168:33-45,
1988.
23. Mizuochi, T., D, McKean, and A. Singer: IL-1 as a co-factor for lymphokine-secreting CD8+
murine T cells. Journal of Immunology 141:1671-1575, 1988.
24. Rosenberg, A. S., T. Mizuochi, and A. Singer: Cellular interactions resulting in skin allograft
rejection. Annals of the New York Academy of Sciences 532:76-86, 1988.
25. Shearer, G. M., A. Singer, T. Mizuochi, M. Buller, A. Hugin, and H. C. Morse III: Importance
of CD8+ T helper cell function in AIDS. Journal of Infectious Diseases 158:893, 1988.
26. Mizuochi, T., A. W. Hugin, H. C. Morse III, A. Singer, and M. Buller: Role of lymphokine
secreting CD8+ T cells in cytotoxic T lymphocyte responses against vaccinia virus.
Journal of Immunology 142:270-273, 1989.
2
Fukushima, K. Okuyama, H. C. Morse III, and K. Komuro: A selective singaling defect in
helper T cells induced by antigen presenting from mice with acquired immunodeficiency
syndrome. Journal of Immunology 144:313-316, 1990.
29. Mizuochi, T., M. Kasai, T. Kokuho, T. Kakiuchi, and K. Hirokawa: Medullary but not cortical
thymic epithelial cells present soluble antigens to helper T cells. Journal of Experimental
Medicine 175:1601-1605, 1992.
30. Okada, Y., K. Suzuki, K. Komuro, and T. Mizuochi: High frequency of transmission of
MAIDS virus in C57BL/10 mice via mother's milk. Journal of Virology 66:5177-5182, 1992.
33. Suzuki, K., M. Makino, Y. Okada, J. Kinoshita, R. Yui, H. Kanazawa, H. Asakura, M. Fujiwara,
T. Mizuochi, and K. Komuro: Exocrinopathy resembling Sjogren's syndrome induced by a
murine retrovirus. Laboratory Investigation 69:430-435, 1993.
34. Suzuki, K., M. Fujiwara, and T. Mizuochi: Exocrinopathy resembling Sjogren's syndrome
induced by a murine retrovirus: implication for a new animal model. In Proceeding of the 4th
International Symposium on Sjogren's syndrome. pp171-173, 1993.
35. Sugita-Konishi, Y., S. Kumagai, and T. Mizuochi: The cytotoxicity on murine T cells of
macrocyclic trichothecenes, roridin A and verrucarin A, are reduced by Ia-negative splenic
adherent cells. Toxicon 32:1051-1057, 1994.
39. Shoji-Tanaka, A., T. Mizuochi, and K. Komuro: Gene transfer using purified retroviral
3
integrase. Biochemical and Biophysical Research Communications 203:1756-1764, 1994.
40. Uehara, S., Y. Hitoshi, F. Numata, M. Makino, M. Howard, T. Mizuochi, and K. Takatsu:
IFN-γ-dependent pathway plays a critical role in the pathogenesis of murine immunodeficiency
syndrome induced by LP-BM5 murine leukemia virus. International Immunology
6:1937-1947, 1994.
41. Mizuochi, T., S.-T. Yee, M. Kasai, T. Kakiuchi, D. Muno, and E. Kominami: Both cathepsin B
and cathepsin D are necessary for processing of ovalbumin as well as for degradation of class
II MHC invariant chain. Immunology Letters 43:189-193, 1994.
42. Kasai, M., K, Hirokawa, K. Kajino, K. Ogasawara, M. Tatsumi, E. Hermel, J. J. Monaco, and T.
Mizuochi:Difference in antigen presentation pathways between cortical and medullary thymic
epithelial cells. European Journal of Immunology 26:2101-2107, 1996.
43. Kimoto, H., H. Nagaoka, Y. Adachi, T. Mizuochi, T. Azuma, T. Yagi, T Sata, S. Yonehara, Y.
Tsunetsugu-Yokota, M. Taniguchi, and T. Takemori: Accumulation of somatic hypermutation
and antigen-driven selection in rapidly cycling surface Ig+ germinal center (GC) B cells which
occupy GC at a high frequency during the primary anti-hapten response in mice.
European Journal of Immunology 27:268-279, 1997.
44. Yee, S.-T., E. Abe, Y. Okada, Y. Matsuura, Y. Takebe, K. Ogasawara, H. Takahashi, and T.
Mizuochi: A polypeptide encoded within the murine AIDS defective virus stimulates primary
proliferation of CD8+ T cells. Immunology Letters 55:93-98, 1997.
46. Hori, J., M. Isobe, S. Yamagami, T. Mizuochi, and T. Tsuru: Specific immunosuppression of
corneal allograft rejection by cmbination of anti-VLA-4 and anti-LFA-1 monoclonal antibodies
in mice. Experimental Eye Research 65:89-98, 1997.
47. Suzuki, K., T. Narita, R. Yui, K. Ohtsuka, S. Inada, T. Kimura, Y. Okada, M. Makino, T.
Mizuochi, H. Asakura, and M. Fujiwara: Unique intenstinal inflammatory lesions induced by
the transfer of lymphocytes from mice infected with retrovirus. GUT 41:221-228, 1997.
48. Okada, Y., E. Abe, K. Komuro, and T. Mizuochi: Heterosexual transmission of murine AIDS
virus. Journal of Virology 72:2451-2453, 1998.
49. Kasai, M., E. Kominami, and T. Mizuochi: The antigen-presentation pathway in medullary
thymic epithelial cells, but not that in cortical thymic epithelial cells, conforms to the endocytic
pathway. European Journal of Immunology 28:1867-1876, 1998.
50. Mizuochi, T., A. Horino, and T. Uchida: Delayed progression of murine AIDS in C57BL/6
mice preimmunized with a highly antigenic 10-mer peptide encoded by the murine AIDS
defective virus gag p12 gene. Vaccine 16:2026-2030, 1998.
51. Odaka, C., and T. Mizuochi: Role of macrophage lysosomal enzymes in the degradation of
nucleosomes of apoptic cells. Journal of Immunology 163:5346-5352, 1999.
52. Muno, D., E. Kominami, and T. Mizuochi: Generation of both class I- and class II-restricted
antigenic peptides from exogenously added ovalbumin in murine phagosomes. FEBS Letters
4
478:178-182, 2000.
53. Kamiya K, J. Hori, F. Kagaya, T. Usui, S. Amano, T. Oshika, T. Mizuochi, T. Tsuru, and S.
Yamagami: Preservation of donor cornea prevents corneal allograft rejection by inhibiting
induction of alloimmunity. Experimental Eye Research 70:737-743, 2000.
54. Odaka, C., and T. Mizuochi: Angiotensin-converting enzyme inhibitor captoril prevents
activation-induced apoptosis by interfering with T cell activation signals. Clinical
Experimental Immunology 121:515-522, 2000.
57. Kasai, M., H. Kropshofer, A. B. Vogt, E. Kominami, and T. Mizuochi: CLIP-derived peptides
bound to class II MHC molecules of medullary thymic epithelial cells differ from those of
cortical thymic epithelial cells in their diversity, length, and corboxyl terminal processing.
European Journal of Immunology 30:3542-3551, 2000.
58. Yoshizawa, I., Y. Soda, T. Mizuochi, S. Yasuda, T. A. Rizvi, T. Mizuochi, T. Takemori, and Y.
Tsunetsugu-Yokota: Enhancement of mucosal immune response against HIV-1 Gag by DNA
immunization. Vaccine 19:2995-3003, 2001.
59. Committee for Evaluation of In Vitro Diagnostic Devices, National Institute of Infectious
Diseases: Re-evaluation of HBsAg detection kits approved for marketing in Japan.
Japanese Journal of Infectious Diseases 54:201-207, 2001.
60. Odaka, C., and T. Mizuochi: Macrophage are involved in DNA degradation of apoptic cells in
murine thymus after administration of hydrocortison. Cell Death and Differentiation
9:104-112, 2002.
61. Odaka, C., T. Mizuochi, T. Shirasawa, P. Morain, and F. Checler: Murine T cells expressing
high activity of proryl endopeptidase are susceptible to activation-induced cell death.
FEBS Letters 512:163-167, 2002.
62. Committee for Evaluation of In Vitro Diagnostic Devices, National Institute of Infectious
Diseases: Re-evaluation of HCV Ab detection kits approved for marketing in Japan. Japanese
Journal of Infectious Diseases 55:33-36, 2002.
64. Odaka, C., T. Mizuochi, J. Yang, and A. Ding: Murine macrophages produce secretory
leukocyte protease inhibitor during clearance of apoptotic cells: Implications for resolution of
5
the inflammatory response. Journal of Immunology 171:1507-1514, 2003.
67. Kasai M, and Mizuochi T: Derivation, culture, and characterization of thymic epithelial cell
lines. Methods Mol Biol. 380:107-24, 2007.
68. Mizuochi T, Ito M, Takai K, and Yamaguchi K: Differential susceptibility of peripheral blood
CD5+ and CD5− B cells to apoptosis in chronic hepatitis C patients. Biochemical and
Biophysical Research Communications 389:512-515, 2009.
69. Ito M, Mizoroki F, Takai K, Yamaguchi K, and Mizuochi T: Phenotypes and gene expression
profiles of peripheral blood mononuclear cells in chronic hepatitis C patients who developed
non-Hodgkin’s B-cell lymphoma. Biochemical and Biophysical Research Communications
390:269-272, 2009.
70. Kasai M, Tanida I, Ueno T, Kominami E, Seki S, Ikeda T, and Mizuochi T: Autopahgic
compartments gain access to the MHC class II-compartments in thymic epithelium. Journal of
Immunology 183:7278-7285, 2009.
71. Mohsan S, Suzuki R, Kondo M, Aizaki H, Kato T, Mizuochi T, Wakita T, Watanabe H, and
Suzuki T: Evaluation of hepatitis C virus core antigen assays for detecting recombinant viral
antigens derived from various genotypes. Journal of Clinical Microbiology 47:4141-4143,
2009.
72. Mizuochi T, Mizusawa S, Nojima K, Okada Y, and Yamaguchi K: Single amino acid
substitution in the hepatitis B virus surface antigen (HBsAg) “a” determinant affects the
detection sensitivity of an HBsAg diagnostic kit. Clinica Chimica Acta 411:605-606, 2010.
76. Mizuochi T, Ito M, Takai K, and Yamaguchi K: Resistance of peripheral blood memory B cells
to apoptosis in chronic hepatitis C patients. Virus Research 155:349-351, 2011.
77. Ito M, Kusunoki H, Mochida K, Yamaguchi K, and Mizuochi T: HCV infection and B-cell
lymphomagenesis. Advances in Hematology (2011, in press)