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DOC/LP/01/28.02.

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LESSON PLAN
Sub Code & Name : BT2251 Basic Industrial Biotechnology

LP- BT2251 LP Rev. No: 00 Date: 15/12/2010 Page 1 of 6

Unit: 1

Branch: BIOTECHNOLOGY Semester : IV

Unit syllabus: INTRODUCTION TO INDUSTRIAL BIOPROCESSES A historical overview of industrial fermentation process-traditional and modern biotechnology. A brief survey of organisms, processes, products related to modern biotechnology. Process flow sheeting-block diagrams, pictorial representations. Objective: To introduce the Basic concepts of fermentation technology. Session No 1 Topics to be covered Historical overview of industrial fermentation products. Comparison between traditional and modern methods of fermentation. Industrially useful microorganisms and its products. Basic design of the Fermentor Time min 50 Ref TB1 (7-13) TB 2 (14-19) TB1 (14-20) 50 TB1 (21-22) 50 TB1 (25-42) 50 TB1 (42-59) 50 TB3 (74-80) Teaching Aids BB/OHP

BB/OHP

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Overview of Fermentation processes Process flow sheeting-block diagrams and flow sheets. Review

BB/OHP

50

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DOC/LP/01/28.02.02

LESSON PLAN
Sub Code & Name : BT2251 Basic Industrial Biotechnology

LP- BT2251 LP Rev. No: 00 Date: 15/12/2010 Page 1 of 6

Unit: 2

Branch: BIOTECHNOLOGY Semester : IV

Unit syllabus: PRODUCTION OF PRIMARY METABOLITES A brief outline of processes for the production of commercially important organic acids (Citric acid, lactic acid, acetic acid etc.), amino acids (Glutamic acid, phenylalanine, aspartic acid etc.) and alcohols (ethanol, Butanol etc.) Objective: To discuss in detail the production of primary metabolites. Session No 8 9 10 11 12 13 14 15 16 17 Topics to be covered Citric acid production. Lactic acid production Acetic acid production and outline of process for production of other commercially important organic acids. Glutamic acid production Phenylalanine production Aspartic acid production and outline of process for production of other commercially important amino acids Ethanol production Butanol production Outline of process for production of other commercially important alcohols. Review Time min 50 50 50 50 50 50 50 50 50 Ref TB1 (403-407) TB1 (304-313) TB1 (333-343) TB1 (7-13) TB1 (151-157) TB3 (150-156) TB3 (299-303) TB1 (260-273) TB1 (277-283) Teaching Aids BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP

DOC/LP/01/28.02.02

LESSON PLAN
Sub Code & Name : BT2251 Basic Industrial Biotechnology

LP- BT2251 LP Rev. No: 00 Date:15/12/2010 Page 3 of 6

Unit: 3

Branch: BIOTECHNOLOGY Semester : IV

Unit syllabus: PRODUCTION OF SECONDARY METABOLITES Study of production processes for various classes of secondary metabolites: antibiotics, beta-lactams (penicillin, cephalosporin etc), amino glycosides (streptomycin), macrolides (erythromycin), vitamins and steroids. Objective: To impart knowledge, to discuss in detail the production of secondary metabolites. Session No 19 20 21 22 23 24 25 26 27 28 Topics to be covered Overview of production process of antibiotics. Production of penicillin. Cephalosporin production Streptomycin production. Overview of production process of macrolides Production of erythromycin. Overview of production process of vitamins Production of commercially important vitamins. Production process of steroids. Review. Time min 50 TB1 (223-247) 50 50 50 50 50 50 TB1 (347-350) 50 TB1 (350-389) 50 TB3 (256-257) TB3 (258-260) TB1 (337-350) TB3 (240-243) TB1 (248-254) Teaching Aids Ref TB1 (221-223) BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP

DOC/LP/01/28.02.02

LESSON PLAN
Sub Code & Name : BT2251 Basic Industrial Biotechnology

LP- BT2251 LP Rev. No: 00 Date: 15/12/2010 Page 4 of 6

Unit: 4

Branch: BIOTECHNOLOGY Semester : IV

Unit syllabus: PRODUCTION OF ENZYMES AND OTHER BIOPRODUCTS. Production of industrial enzymes such as proteases, amylases, lipases, cellulases. Production of biopesticides, biofertilizers, biopreservatives (nisin), cheese, biopolymers (xanthan gum, PHB), single cell protein. Time Session Teaching No Topics to be covered Ref Aids 29 30 31 32 33 34 35 36 Production of Proteases & amylases Production of lipases & cellulases Production of biopesticides Production of biofertilizers. Production of Nisin and cheese. Production of xanthan gum & PHB Production of SCP. Review. TB1 (395-398) 50 TB1 (400-402) 50 50 50 50 50 50 TB3 (301-304) TB3 (219,286) TB3 (231,247) TB3 (70,330) TB3 (69-73, 306-313) BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP

DOC/LP/01/28.02.02

LESSON PLAN
Sub Code & Name : BT2251 Basic Industrial Biotechnology

LP- BT2251 LP Rev. No: 00 Date: 15/12/2010 Page 5 of 6

Unit: 5

Branch: BIOTECHNOLOGY Semester : IV

Unit syllabus: PRODUCTION OF MODERN BIOTECHNOLOGY PRODUCTS Production of recombinant proteins having therapeutic and diagnostic applications, production of vaccines, production of monoclonal antibodies, products of plant and animal cell culture. Session No 37 38 39 40 41 42 43 44 45 46 Time Topics to be covered min Production of recombinant proteins. I Production of recombinant proteins .II Production of recombinant proteins .III Production of vaccines I Production of Vaccines II Production of monoclonal antibodies Products of plant cell culture Products of animal cell culture. Review Final review. TB4 (227-243) 50 TB4 (227-243) 50 TB4 (227-243) 50 TB4 (286-298) 50 TB4 (286-298) 50 50 50 50 50 TB4 (286-298) TB3 (231-232) TB3 (145-147) BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP BB/OHP Ref Teaching Aids

Course Delivery Plan: Week


Units

1 III I 14 III

2 III

3 III II

4 III

5 III

6 III

7 III III

8 III

9 III

10 III IV

11 III

12 III V

13 III

Week
Units

15 III

Textbooks: 1. Casida Jr,L.E,Industrial microbiologyNew age international Ltd. 2. Presscott,Dunn,Industrial Microbiology,Agrobios (India) References: 3. Wulf Cruger and Anneliese cruegerBiotechnology:a text book of industrial Microbiology, panima publishing corporation. 4. Murrey Moo & Young Comprehensive Biotechnology, Pergamon. 5. A.H.Patel,Industrial Microbiology, Macmillan publishers India Ltd, Agriculture and Life Sciences.

Prepared by Signature Name Designation Date N. Sathish Asst.Professor 15/12/2010

Approved by Prof. M. Sivanandham Head of the Department 15/12/2010