Generi c Name

Brand Name

Classificatio n

Mechanism of Action

Indication

Contraindication

Side Effects

How Supplied

Dosage & Frequenc y

Nursing Responsibilitie s

Oxytocin

Syntocino n

Oxytocic drug

Acts on smooth muscles of the uterus to stimulate contractions ; response depends on the uterine threshold of excitability id selective for the uterus, especially toward the end of pregnancy, during labor and immediately following delivery oxytocin stimulates rhythmic contraction of the uterus, increases the

Antepartum: Stimulation of labor at term to overcome true primary or secondary uterine inertia. induction of labor with oxytocin is indicated only under certain specific conditions & not usual because serious toxic affects can occur oxytocin Indicated: 1. for uterine inertia 2. for induction of labor in case of erythroblasto sis fetalis, maternal diabetes mellitus preeclampsia

Hypersensitivit y to drug significant cephatopelvic disproportion, unfavorable fetal position that are undeliverable w/o conservation prior to delivery in obstetric emergencies where the benefit-to-risk ratio for either the mother of fetus favors surgical intervention.

GU: pelvic hematoma postpartum hemorrhage . rupture of the uterus, spasm, titanic contraction, uterine hyper tonicity.

Injection: 10units / ml

Control of postpartum bleeding. Give 10 units after delivery of the placenta.

Docume nt indicatio n for therapy, onset and character istics of symptom s. Note sensitivit y to the drug. Determin e fetal maturity, pelvic adequacy , fetal presentat ion. Provide continuo us observati ons of client checking for character

frequency of 3.for induction existing of labor after contractions premature and raises rupture id the tone of membranes uterine musculature . Spratto, woods, 2007 pp.1044

istic of uterine contracti ons.

Generic Name

Brand Name

Classificat ion

Mechanism of Action

Indication

Contraindicat ion

Side Effects

How Supplied

Dosage & Frequency

Nursing responsibilities

Methylerg onovine maleate

Methergi ne

Oxytocic drug

Synthetic drug to ergonovine . Acts directly on the uterine smooth to stimulate the rate, tone, and amplitude of uterine contraction . It induces a rapid, sustained titanic uterotonic effect that shortens the third stage of labor and reduces blood loss. The uterus becomes more sensitive to the drug

Use with caution in sepsis, obliterati ve vascular disease, impaired renal or hepatic function, during the second stage of labor, and during lactation. Do not routinely use IV due to possible induction of sudden hypertens ion and CVA.

Pregnancy, toxemia, hypertensio n. Ergot hypersensiti vity. To induce labor or threatened spontaneous abortions. Administrati on before delivery of the placenta. Use with CYP3A4 inhibitors (e.g., protease inhibitors, macrolide antibiotics, azole antifungal drugs).

CV: Hypertens ion that may be associated with seizure or headache; hypotensi on, acute MI, thrombop hlebitis, palpitation , transient chest pains. GI: N&V, diarrhea, foul taste. CNS: Dizziness, headache, tinnitus, hallucinati ons, seizures.

Injection:0 .2 mg/mL; Tablets: 0.2 mg

IM; IV (EME RGEN CIES ONLY ) 0.2 mg q 2-4 hr following delivery of placenta, of the anterior shoulder, or during the puerperiu m. TABL ETS 0.2 mg 3- 4 times per day in the puerperiu m for a maximum of 1 week

Documen t indicatio ns for therapy, onset, and characteri stics of S&S. avoid with liver or renal dysfuncti on. List drugs prescribe d to ensure none interact. Documen t fundal tone and nonphasi c contractu res; massage to check for

toward the end of pregnancy. Decrease in bioavailabi lity after PO use probably due to first-pass metabolis m in the liver. Spratto, woods, 2007 pp.887888

Miscellan eous: Sweating, dyspnea, hematuria, water intoxicatio n, leg cramps, nasal congestion .

relaxatio n or severe cramping . Monitor baseline calcium; correct if low to improve

drug effectiveness. Monitor prolactin levels; assess for decreased milk production. With postpartu m bleeding, report frequency , amount, color, and associate d S&S.

Generic Name

Brand Name

Classification

Mechanism of Action

Indication

Contraindicati on

Side Effects

How Supplied

Dosage & Frequency

Nursing Responsibilitie s

Mefenami Acidan c Analcid Acid Aprostal Biostan Calibral Dolfenal Dolmetin e Escandar Fendal Fenexan Garden Gifsen Harpinac Istan Isagesic Mecid-a Midiano n Mefenax Pacimic Ponstan Proxyl Ralgec Revelan Selmac Sensome

Analgesics Aspirin-like Antipyretics drug that has and muscle analgesic, relaxants antipyretic and anti noninflammatory steroidal activities. anti these inflammator activities y drugs. appear to be due to its ability to inhibit cyclooxygena se and also antagonize certain effects of prostaglandins . mefenamic acid displays central and peripheral activities.

Relief of pain including muscular rheumati c, traumatic , dental, post operative and post partum pain, headache , migraine, fever. soft tissue injuries. should not exceed 7 days.

Pregnancy and lactation. active ulceration and or chronic inflammation of either upper and lower GIT. blood disorders, platelet function. Kidney or liver impairment. Children less than 14 yo.

Headache Dizziness Somnolenc e Insomia ]fatigue Tiredness Tinnitus.

Capsul e: 500 mg, 200 mg.

Adult- 500 Obtain mg baseline followed assessment by 250 mg of pain every 6-8 before hrs. starting therapy. Suspensio Monitor for n: adverse pediatrics reactions. 25 mg/kg increase water intake Assess diet and nutrition. assess knowledge regarding drug therapy Remind patient that poisoning may occur if increased beyond recommende

t Spegic Totagesic PPDS Nursing Drug Guide 2007 Edition p. 22

d level. Be sure to keep drugs away from children. Monitor vital signs.

Generic Name

Brand Name

Classificatio n

Mechanism of Action

Indication

Contraindication

Side Effects

How Supplied

Dosage & Frequenc y

Nursing Responsibilitie s

Amoxicilli n

Amoxal AntiAmusa infectives Athenalyn Axmel Bactigent Cartrimox Diasamox Clearamo x Eleomox Emilex Globamo x Globapen Harvemo x Himox Lewixin Littmox Macropag e Megamox Medimoxi l Novamox Pediamox Promox

Prevents bacterial cell wall synthesis during replication. bactericida l. PPDS Nursing Drug Guide 2007 Edition p. 77

Treatment of incfections of respiratory tract Skin and skin structures Genitourinar y tract Otitis media Meningitis Septicemia sinusitis

Hypersensitivit y to penicillin, imipenem. Not used to treat severe pneumonia Empyema Bacteremia Pericarditis

Dizzines s Nausea Vomitin g

Capsules Powder for oral suspensio n Tablets Tablets chewable

Obtain 250 to baseline 500 mg assessment every 8 of iron hours deficiency before Children starting - 20 to therapy. 40 obtain mg/kg a patients day history of allergy Monitor for bleeding. Monitor for adverse reactions. assess bowel elimination, increase water intake Assess diet and nutrition. assess knowledge

Sumoxil Teramoxil Texil Valzimox Vaxman Zymoxil

regarding drug therapy Remind patient that poisoning may occur if increased beyond recommend ed level. Be sure to keep drugs away from children.