Challenges&OpportunitiesinMedicalInnovation Iowa'sLeadershipRoleinCreatingJobs& ImprovingHealthinthe21stCentury

PANELISTBRIEFINGMATERIALS
EventOverview

Historically,theUnitedStateshasbeentheworldwideleaderinmedicalinnovationand scientificdiscovery.Thisleadershippositionisoneofthecountrysgreateststrengths.In additiontogeneratingthousandsofwellpayingjobsinAmerica,medicalinnovation developsproductsandtechniquesthatbenefitthehealth,socialwellbeingandsafetyof patientsaroundtheglobe.Iowaisuniquelypositionedtocontinuetomoveintoa leadershiproleinthissector,withoutstandingeducationalinstitutions,strongworkethic, andablossominglifesciencessectorencompassinghuman,plantandanimalhealth. However,Americanleadershipinmedicalinnovationisatrisk.Inrecentyears,therehas beenadeclineinthenumberofscientificresearchers,degreesissuedinscienceand engineering,andnewpatentsissuedinthiscountry.Economicpressures,bothnationally andatthestatelevel,areputtingresearchintensive,innovativesectorsatrisk.National pressuresincreasechallengesonthestatelevel,andresearchintensive,innovativesectors oftheeconomyareatrisk.Thisleadstothecentralquestionsfortheday: WhatroledoesmedicalinnovationplayinleadingAmericaforwardinjobgrowth, andeconomicrecovery? WhatdoesAmericanmedicalinnovationneedtostaygloballycompetitive,andhow canourfederalleadersinWashingtonprovideapathwayforsuccess? Whatdoourpatientsneedfromthemedicalinnovationsectorandwhatpoliciesare importanttoensurethat21stcenturycuresarenotonlydeveloped,butthatthey reachthepatientsforwhichtheyareintended? Howcaninnovationsinlifesciencesandmedicaltechnologiesreducethecostof healthcare? HowisIowacurrentlyleadingtheway? Whatisthenextlevel,andhowdoweasastategetthere? Frombothafederalandstateperspective,howcanIowaimproveineducatingthe besttalentandworktoretainthemforthebenefitofourstateseconomy? Howcanthepublicandprivatesectorsworkmorecloselytogethertofacilitatethe developmentofnewsciencethatleadstobreakthroughsinmedicalinnovation?

 OnFridayAugust26th,TheCouncilforAmericanMedicalInnovation,inpartnershipwith Innovate Iowa, the Iowa Biotech Association, Des Moines Area Community Colleges, the Greater Des Moines Partnership and the American Cancer Society - Midwest Division invite you to attend and engage in an important morning-long discussion. Thismedicalinnovationsymposiumwillexaminethemosteffectivefederalandstate policystrategiessupportingU.S.medicalinnovationasacornerstoneforjobcreation, economicrecoveryandpatienthealthforallAmericans.Paneldiscussionswillinclude globalbusinessleaders,policymakers,economicstrategists,academicscholars,and experts,allcontributingtothisurgentdialogueonhowtheU.S.cannavigatecurrent challengesandstaythecourseasaworldwideleaderinmedicalinnovation.

EventRunOfShow

8:00 a.m. 8:25 a.m. 8:25 a.m. 8:30 a.m. 8:30 a.m. 8:45 a.m.

Event Registration Welcome and Intro of Sen. Harkin Rob Denson DMACC Opening Remarks - Introduction of National Conversation & Role/Mission of the HELP Committee for 2011/2012 Senator Harkin frames the issues and welcomes Begala to intro National Panel Panel One American Medical Innovation at a Crossroads Paul Begala provides bio for each panelist followed by moderated discussion and audience Q&A. Panelists include: Moderator: Begala Dr. Ken Thorpe Professor & Chair, Rollins School of Public Health, Emory University, and Executive Director, PFCD Dr. Chris Coburn Executive Director, Cleveland Clinic Innovations Dr. John Orloff - Chief Medical Officer & Senior Vice President, Global Development, Novartis Pharma, AG Marc Boutin, JD, - Executive Vice President & Chief Operating Officer National Health Council Panel Transition Iowas Leadership Role in Medical Innovation: Supporting American Jobs & Patient Health Senator Harkin

8:45 a.m. 10:00 a.m.

10:00 a.m. 10:15 a.m. 10:15 a.m. 10:30 a.m.

10:30 a.m. 11:45 a.m.

Panel Two Charting Iowas Course for Leadership in Medical Innovation Paul Begala provided bio for each panelist followed by moderated discussion and audience Q&A. Panelists include: Moderator: Begala Greg Geoffroy President, Iowa State University Dr. Doug Bartles Vertex Pharmaceuticals Rachel Hurley Executive Director, Iowa Biotech Association Dr. George Weiner University of Iowa, Holden Cancer Institute Press Availability

11:45 a.m. 12:00 p.m.

PanelOverviewandYourRole
Thankyouforagreeingtoparticipateinthisimportantevent. Theformatofthisdiscussionwillbemuchlikeatalkshow.Panelistswillbeseatedinclubchairs nexttoeachothertoencourageopenandinformaldialogue.Therewillbenoformalpresentations madebythepanelists,sonoPowerPointorothervisualswillbenecessary.Therewill,however,be anopportunityforeachpanelisttogiveathreeminuteopeningstatementtoframetheirmission androleinthedebate.Thetimelimitontheopeningstatementwillbeenforcedtokeepthe discussionontrack.Thefacilitatedpaneldiscussionwilllastapproximately1hourandwillbe followedbya1015minutequestionandanswersessionwiththeaudience. Thefirstrowofeachaisleofchairsintheaudiencewillbereservedforpanelists.Pleasebeseated by8:20whentheeventbegins.Ifyouareonthenationalpanelupfirst,pleaseproceeddirectlyto yourassignedchaironthestage.MembersoftheIowapanelshouldremainseatedinthefirstrow throughoutthenationalpanel.YouwillbecalledtothestagebyPaulBegalashortlybeforeSenator HarkingivestheopeningfortheIowaportionofthediscussion. Bothpanelswillfocusonaddressingthekeyquestionsoutlinedatthebeginningofthisdocument. Thediscussionwillidentifybestpracticesthatareworkingtoday,obstaclestheUSisfacingwhen competinggloballyforR&Dandmanufacturinginvestments,andrealisticpoliciesthatCongress andtheAdministrationmustconsiderintheneartermtoensurethatstatesarewellpositionedto competeintheglobalmarketplace. Followingintroductions,themoderatorwillaskforabriefopeningstatementfromeachpanelist, andthenbeginthediscussion.Informaldiscussionwillcontinuefortheremainderofthepanelwith moderatorBegalafacilitatingandguidingtheconversation. Aneventstaffmemberwillsignalthemoderatorwhenthereisapproximately15minutes remaininginthepanel.Atthispoint,panelmemberswilltakequestionsfromtheaudience.The

moderatorwillberesponsibleforcallingonindividualsanddirectingtheirquestionsifnecessary andasappropriate. AttheendofthisQ&A,aneventstaffmemberwillgiveasignaltowrapupthediscussionthe moderatorswillmakebriefclosingremarks. Panelistsmaybeinterviewedbythemediaintheeventroomorintheareaimmediatelyoutsidethe room.

TheAudience
TheForumsaudiencewillbeapproximately100200people.Theseattendeeswillbecomprisedof Congressionalstaff,academics,studentgroups,businessleaders,providerandpatientassociations, thelifesciencesindustry,Councilpartnersandkeymedia.Theeventisfreeandopentothepublic.

IssueOverview:TheNeedforMedicalInnovation
Regardlessofhowonelooksatournationseverchangingmedicallandscape,itisclearthathealth careandeconomicissuesareinextricablylinked.TheU.S.healthsectoraccountsformorethan17 percentofournationsgrossdomesticproducta1.1percentincreasecomparedto2008.While mostindustrieshaveshedjobsinrecentmonths,healthcarehasconsistentlyaddedthem.TheU.S. BureauofLaborStatisticsestimatesthattheindustryhasaddednearly700,000jobssincethestart oftherecession.Today,healthcareisthe#1employerinmostcitiesacrossthecountry. Withoutquestion,thecombinationoffederalfundinginmedicalresearchandinnovation,along withprivateinvestmentandstrongpublicprivatepartnershipscancreatejobsthathelpstimulate localeconomies,bringdownourdeficit,reducehealthcarecostsandpositivelyimpactother industries. Fromlabcoatstohardhats,thejobsandnewbusinessesassociatedwiththiscriticallyimportant sectorrepresentanarrayofhighpayingpositionsacrosshostsofacademicdisciplines, managementfields,healthservicesandskilledtrades.Forexample: InMichigan,thestatewiththehighestunemploymentrateinthecountry,thenumberof peopleworkinginlifesciencesincreasedbymorethan10percentbetween1999and2006, withaveragewagesjumping29percent. InCalifornia,biomedicalbusinessesandresearchinstitutionsemploymorethan235,000 workers.Arecentpublicopinionpollfoundthat96percentofvotersinthestatebelieve thattechnologyandinnovationareanessentialpartofthestate'seconomy. AndaccordingtotheAssociationofAmericanMedicalColleges,medicalschoolsand teachinghospitalsinIowaalonehaveacombinedeconomicimpactof$4.1billion.In Virginia,theeconomicimpactis$9.1billion.InOhioandCalifornia,theimpactis$24.5and $35.5billion,respectively.

Overthepast30years,ournationhasbecomethegloballeaderinbiomedicaldevelopmentbecause ofourworldclassmedicalinnovationecosystem.From1980to2000,thedeathratefromheart attackswascutbynearlyhalfduetoclotinhibitingdrugs,angioplastyandrevascularization proceduresand,implantablecardiacdefibrillators.Manyofthesetreatmentsandtechnologieswere developedrighthereintheUnitedStates. Withskyrocketingdeficitsandaneconomystillstrugglingtorecoverfromtheworsteconomic recessionsincetheGreatDepression,Americaseconomicleadershipinmedicalinnovationisours tolose.Itsclearthatweneedtotakethebestofwhatworksandinnovateourwaythroughthe healthandeconomiccrises. U.S.leadershipisnotetchedinstone,butdependentonourabilitytoidentifyandimplementpro growthideaswhilecultivatingfutureinnovatorsandleadersacrosshealthandmedicine.

AbouttheCouncilforAmericanMedicalInnovation

Mission
TheCouncilforAmericanMedicalInnovationbelievesthatAmericaneedstoinnovateitswayoutof thiseconomiccrisis.Itsmissionisto: EducatethepublicabouttheimportanceofmedicalinnovationintheUnitedStatesandits impactonourcountryseconomy,healthandwellbeing. Driveacomprehensivepublicpolicyagendathatadvancesmedicalinnovation. Encouragepolicymakerstomakemeaningfulchangesoncriticalissuesrelatedtomedical innovation.

TheOpportunity:Americasfutureprosperityandhealthwilllargelydependon maintainingaleadroleinscientific,technologicalandmedicalinnovation.

Americanmedicalinnovationcompaniesemployhighlyskilledresearchersandscientistswho developbreakthroughmedicinesandgenerateemploymentformillions. Americanbusinessesareoperatinginagloballycompetitiveeconomyinwhichtheymust innovatetosucceed.Medicalinnovationkeepsourworkforcehealthyandproductivewhich maintainsUnitedStatescompetitivenessinallareas.

TheChallenge:Americaislosingthisimportantleadershippositiontocountriesthat havemadeinnovationapriority.

AstudyreleasedinFebruary2009bytheInformationTechnologyandInnovationFoundation foundthat,whiletheU.S.currentlyrankssixthamong40countriesandregionsininnovation andcompetitiveness,itplacedlastintermsofprogressmadeoverthelastdecade.Singapore, Sweden,Luxembourg,DenmarkandSouthKoreanowoutranktheU.S.Thesecountrieshave beenadoptingpoliciesthatnurtureinnovation,anditisworking. TheshareofU.S.patentsisdecreasingcomparedtotherestoftheworld,asisourshareof individualswithadvanceddegreesinthesciencesandengineering.Inthepast25years, Americasshareofscientificresearchersfellfrom41%to29%andthenumberofnew doctoratesinscienceandengineeringintheU.S.decreasedby30%.

Todayspolicydecisionswilllikelyhavealongtermimpactonthefutureofmedicalinnovation intheUnitedStates.Researchshowsthat94%ofmedicalinnovationprofessionalssee governmentpolicyascriticaltothesuccessofthemedicalinnovationindustry.Only30%give thegovernmentpassinggradesonthiskeyissue,while70%givethegovernmentpoormarks.

TheSolution:TheCouncilforAmericanMedicalInnovationisworkingin partnershiptowardanationalpolicyagendaaimedatprotectingAmerican leadershipinmedicalinnovation.

Timemagazinereports,Unlessthingschange,thebreathtakingburstofdiscoverythathasbeen drivingoureconomyforthepasthalfcenturywillbeover. TheCouncilforAmericanMedicalInnovation,madeupofleadersfromresearch,medicine, academia,education,patientadvocacy,laborandbusinesscommunities,areadvocatingfora nationalmedicalinnovationpolicyagendathat: Increasesincentivesforinvestmentinresearch,developmentanditsapplication. Increasesinvestmentinthelifesciences. EnsuresanincreasinglyhighlyskilledandtrainedworkforceintheUnitedStates. TheCouncilviewsAmericanleadershipinmedicalinnovationasakeypartofoureconomic recovery.

Leadership
CoChair:DickGephardt(ServedasbothHouseMajorityLeader(19891995)andHouse DemocraticLeader(19952003)) CoChair:GovernorMikeLeavitt(DepartmentofHealthandHumanServicesSecretary(2005 2009), EnvironmentalProtectionAgencyAdministrator(20032005),UtahGovernor(19932003)) President:DebraLappin(SeniorVP,B&DConsulting,formerNationalChair,NationalArthritis Foundation)

AdvisoryBoardandPartners
TheCouncilforAmericanMedicalInnovationincludesleadersinresearch,medicine,academia, education,labor,business,healthcareandpolicy.Theseorganizationsandindividualshaveastake inthefutureofmedicalinnovationandawillingnesstoassistineffortstocreatemeaningfulpublic policychanges. TheCouncilspartnersareworkingwithitsadvisoryboardtohelpdefine,supportanddrive policiesthatwillpreserveAmericasleadershippositioninmedicalinnovation. TheCouncilscurrentpartnersandadvisoryboardmembersinclude: MargaretAnderson,ChiefOperatingOfficer,FasterCures MarcBoutin,J.D.,ExecutiveVicePresidentandChiefOperatingOfficer,NationalHealth Council SteveGibson,VicePresidentofGovernmentRelationsandPublicAffairs,ALSAssociation

DavidHeil,PresidentofDavidHeil&Associates,Inc.,andFormerhostofPBSseries "Newton'sApple" RusselKaufman,M.D.,PresidentandCEOoftheWistarInstitute NancyL.Johnson,SeniorPublicPolicyAdvisor,Baker,Donelson,Bearman,Caldwell& Berkowitz,PC,andformerChairwomanoftheHouseWaysandMeansHealthSubcommittee DavidNash,M.D.,M.B.A.,FoundingDean,JeffersonSchoolofHealthPolicyandPopulation HealthatThomasJeffersonUniversity AmyComstockRick,ChiefExecutiveOfficer,Parkinson'sActionNetwork AdvaMed,www.advamed.org TheAIDSInstitute,www.theaidsinstitute.org ALSAssociation,www.alsa.org AmericanSocietyforRadiationOncology,www.astro.org AmericanAcademyforChildandAdolescentPsychiatry,www.aacap.org AmericanAcademyofNursing,www.aannet.org AssociationofAmericanUniversities,www.aau.edu AssociationofClinicalResearchOrganizations,www.acrohealth.org BiotechnologyIndustryOrganization(BIO),www.bio.org ClevelandClinic,www.my.clevelandclinic.org CollegeofPhysiciansofPhiladelphia,www.collphyphil.org Leukemia&LymphomaSociety,www.lls.org NationalHealthCouncil,www.nationalhealthcouncil.org NationalOrganizationforRareDisorders,www.rarediseases.org NationalVentureCapitalAssociation,www.nvca.org ParkinsonsActionNetwork,www.parkinsonsaction.org PharmaceuticalResearch&ManufacturersofAmerica(PhRMA),www.phrma.org RetireSafe,www.retiresafe.org WhitmanWalkerClinic,www.wwc.org

Formoreinformation,pleasevisitwww.americanmedicalinnovation.org.