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Course Outline Advanced Biology Unit I

Lecturer: Mobile: Email: Lab Technician:

Stuart LaPlace To be announced.. stuartlaplace@gmail.com Ms. Cherissa Tuckett

If you contact me at the aforementioned number please leave a message, I check my messages daily. Please make sure to check your emails regularly during the semester as special announcements and pertinent information will be posted from time to time. *Office hours pending the next time table You can find me in the Biology Lab during the above mentioned hours. Please make an appointment to discuss any concerns or issues via any one of the contact media given. Course Description Prerequisite for Advanced Biology Unit I: - CSEC Biology & Chemistry. - Lecturers discretion This introductory Biology Course is multi-disciplinary in nature and considers a good working knowledge of CSEC Biology and Chemistry. This course is designed to present a smorgasbord of perspectives relating to various topics in Biology such as; cell and molecular Biology, genetics, variation, natural selection and reproduction. Significant attention will be given to understanding these perspectives as they apply to Biology. There are labs accompanying the lectures that will be used for your internal assessment. The course is dissected across three (3) modules that are clearly defined in the syllabus along with the objectives. (You will need to buy the syllabus)

Course Evaluation Presentation Quizzes (10 quizzes) Module Test (3 tests) Homework Assignments 20% 20% 50% 10%

A midterm will be administered in November to test your competence in two modules and successful passes along with attendance and overall class performance will determine if you are competent enough to proceed with this course. Your performance on the course evaluation dictates who sits the final exam from CAPE. Your IA marks will be used in conjunction with the final to determine your grade. In essence, poor labs would yield a poor final grade. There will be no make-up end of module tests or quizzes. If you are absent on the day it is written you will be required to notify me and have a valid excuse for consideration. Late Policy Due dates for assignments and exams are the same for all Biology students and are nonnegotiable. Assignments passed in late will be penalized at a rate of ten percent for each late day and in addition, you will be not allowed to attend class until assignment is completed. Exceptions may be given for medical circumstances (with verification) as assessed by the lecturer. Required Course Material **Understanding Biology for Advanced Level 4th edition by Glenn & Susan Toole. *Advanced Biology Principles and Practices, 2nd Edition by C. J. Clegg and D.G. MacKean *Biological Science I & II by D.J. Taylor, N.P.O. Green and G.W. Stout *Advanced Biology by Michael Kent *Cambridge Modular Series (Foundation Biology, Central Concepts, Growth & Reproduction, Genetics) ** Biology Practicals Field and Laboratory Experiments Lab Manual by Stuart LaPlace ** Lab Coat **Syllabus ** Compulsory, * optional where first option is not practical

Plagiarism and Cheating There should be no cheating of any kind, no mirror images of work will be accepted. Anyone found guilty of such acts will be rewarded in kind with a grade of zero for the appropriate exercise. Lab results may be shared but write ups should reflect uniqueness.

Language Correct use of language is one of the criteria included in the evaluation of all written assignments. Introduction to course - What is expected of each student for the duration of course - The rules for lab use and conduct in the lab - How lab assignments should be written up and presented - Marking scheme for lab assessments - Penalties associated with deadlines - How text books and resource material should be used - How syllabus is used WEEK 1 Structure and properties of water Structure and function of simple sugars Molecular structure of starch, glycogen and cellulose and their role in living organisms.

WEEK 2 Molecular structure of triglycerides and their role as a source of energy Relationship of triglycerides to obesity Describe the structure of phospholipids and their role in membrane structure and function Amino acid structure Formation and breakage of peptide bonds

WEEK 3 Protein structure Types of bonding (hydrogen, ionic, disulphide) Hydrophobic interactions Molecular structure of haemoglobin, globular proteins, collagen, fibrous proteins.

WEEK 4 Reducing and non-reducing sugars Investigate and compare quantitatively reducing sugar and starch Research Assignment Drawing interpretations (electron micrograph and light microscope) Structure of the light microscope Membrane structures

- Organelle structures WEEK 5 Outline functions of membrane systems and organelles Compare structure and function of typical animal and plant cell Describe structure of prokaryotic cell Compare and contrast prokaryotic cells and eukaryotic cells Concepts of tissues and organs using dicotyledonous roots

WEEK 6 Fluid mosaic model Diffusion, facilitated diffusion and active transport Endocytosis and Exocytosis Metabolism, catabolism, anabolism Enzymes as globular proteins Properties of enzymes (induced fit, active sight, activation energy)

WEEK 7 Effects of PH, temperature and substrate concentration on enzymes Competitive and noncompetitive inhibitors Midterm Test Field Trip

WEEK 8 Module 2: Refer to Syllabus for objectives. Structure of RNA and DNA Drawing of dinucleotides Recognized structural formulas of : nucleotides, ribose, deoxyribose, pyrimidines and purines Nature of hydrogen bonding Importance of hydrogen bonding and base pairing in DNA replication Significance of 5 end and 3 end.

WEEK 9 Semi-conservative replication, genetic code; initiation, transcription, translation, termination Relationship between nucleotide sequence and amino acid sequence in polypeptides Role of DNA and RNA in protein synthesis Different type of RNA and their respective roles Relationship between the structure of DNA, protein structure and phenotype of an organism Relationship between DNA, chromatin and chromosomes

WEEK 10 Describe mitotic cell division (interphase included) Stages of mitosis Importance of DNA replication in genetic stability Role of mitosis in growth, repair and asexual reproduction Homologous pairs of chromosomes Haploid and diploid differentiation and heritable variation (meiosis)

WEEK 11 Patterns of inheritance Monohybrid and Dihybrid crosses Chi-square Test Observe unexpected ratio significance

WEEK 12 Preparations for End of Term test End of Term test Close of first half of Biology Program

SECOND SEMESTER JANUARY WEEK 1 Chi-square test continued Confidence limits and null hypothesis Principle of restriction enzyme Recombinant DNA technology (clones, insulin production) Benefits and hazards of genes therapy (cystic fibrosis)

WEEK 2 Implications of the use of genetically modified organisms Variation in sexually produced organisms Mutations (genes, chromosomes) Implications of changes in DNA nucleotide sequence Mutation and genetic variation Heritable variation and natural selection

WEEK 3 Forces of natural selection (peppered moth, antibiotics) Natural selection as an agent of change/ constancy Natural selection and evolution (Darwin Theory) Biological species concept (inbreeding) Process of speciation (isolating mechanisms)

WEEK 4 Explain asexual reproduction Advantages and disadvantages of asexual reproduction Principles of vegetative propagation Genetic consequences of asexual reproduction

WEEK 5 Structure of the anther and pollen grains Structure of ovule and embryo sac formation Cross fertilization promotion (protogyny, protandry) Genetic consequences of sexual reproduction (self and cross fertilization)

WEEK 6 Events of pollination to fertilization Double fertilization Seed, fruit development and their content Male and female reproductive systems Gametogenesis (secondary oocyte and ovum) Compare the structure of the ovum and sperm

WEEK 7 Relate structure of ovum and sperm to their function How hormones regulate Gametogenesis Hormones and the menstrual cycle Fertilization and implantation Human reproductive anatomy and physiology as they relate to contraceptive methods

WEEK 8 Structure and function of the placenta Function of the amnion Maternal behavior on fetal development Role of nutrition, as it relates to alcohol abuse, legal and illicit drugs and cigarette smoking

WEEK 9 UP TO EXAMS Revision, remaining labs, mock exam, past paper question practice and field trips CLOSE OF BIOLOGY PROGRAM