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DRUG STUDY

GENERIC/ TRADE NAME DOSAGE / FREQUENC Y CLASSIFICAT ION INDICATION CONTRAINDICAT ION SIDE EFFECTS NURSING RESPONSIBILITIES

Salbutamol+ Ipratropium bromide (Duavent)

1 nebule every 6 hours

Bronchodilator COPD agents

Management of reversible bronchospasm associated with obstructive airway diseases in patients who require more than a single bronchodilator

Patients with a history of hypersensitivity to soya lecithin or related food products such as soybean and peanut. Hypertrophic obstructive cardiomyopathy or tachyarrhythmia.

Headache Dizziness Fine tremor of skeletal muscle Nervousness Dryness of mouth Urinary retention Throat irritation Arrhythmia

Assess Vital Signs Before drug administration. Teach patient how to use inhaler properly. Observe for paradoxical bronchospasm (wheezing). If Condition occurs, withhold Medication and notify physician or other health care professional immediately. Instruct patient to rinse mouth after each nebulizer treatment to help minimize throat dryness. Instruct patient to contact health care professional immediately if shortness of breath is not relieved by medication or is accompanied by diaphoresis, dizziness, palpitations, or chest pain.

Acetylcysteine

600mg OD Mucolytic 1 tab to dissolve in glass of water

Acute and chronic respiratory tract affections with abundant mucus secretions.

Hypersensitivity to acetylcysteine. Use with caution or discontinue immediately if bronchospasm occurs.

Rarely, urticaria, bronchospasm, nausea, vomiting, and GI upset.

Doxofylline

400mg tab BID

Bronchodilator

For maintenance therapy in patients suffering with Asthma and Chronic Obstructive Pulmonary Disease (COPD). Bronchial asthma and pulmonary disease with spastic bronchial component.

Hypersensitivity to doxofylline. Acute myocardial infarction. Hypotension Lactation

Palpitations Tachycardia GI upset Nausea Dizziness Nervousness Diaphoresis Irritability

Give medication with meals. Do not administer antidiuretics; follow acetaminophen assays carefully to determine appropriate dosage Instruct patient to report difficulty of breathing or nausea. Monitor heart rate and CNS stimulation. Notify physician if palpitations, chest pain, tachycardia occurs.

Furosemide

40 mg tab

Loop diuretic

Acute pulmonary edema Hypertensio Edema associated with heart failure, cirrhosis, renal disease

History of hypersensitivity to furosemide or sulfonamides Severe renal failure Hepatic coma Pregnancy Lactation.

Dizziness Vertigo Paresthesias Xanthopsia Weakness Headache Drowsiness Orthostatic hypotension Thrombophlebitis Photosensitivity Rash Nausea Anorexia Vomiting Urticaria Urinary bladder spasm Muscle cramps Muscle spasms

Reduce dosage if given with other antihypertensives; readjust dosage gradually as BP responds. Give early in the day so that increased urination will not disturbed sleep. Do not mix parenteral solution with highly acidic solutions with pH below 3.5. Do not expose to light, which may discolor tablets or solutions; do not use discolored drug or solutions. Discard diluted solution after 24 hr. Refrigerate oral solution. Measure and record weight to monitor fluid changes. Arrange to monitor serum electrolytes, hydration, liver, and renal function. Arrange potassium-rich diet or supplement potassium as needed.

Vitamin B Complex

1-2 tabs daily

Vitamins and minerals

Vit Bcomplex deficiencies Neuritis Polyneuritis Neuralgia Arthralgia Myalgia

Hypersensitivity to vitamin B12 or cobalt. Early Lebers disease

Drowsiness Headache Mild diarrhea Nausea Itching Difficulty breathing

Determine reticulocyte count, hematocrit, Vit.B12, iron, folate levels before beginning therapy. Obtain a sensitivity test history before administration Avoid I.V. administration because faster systemic elimination will reduce effectiveness of vitamin. Dont give large doses ofvitaminB12 routinely; drug is lost through excretion. Dont mix parenteral preparation in same syringe with other drugs. Protect Vit.B12 from light. Dont refrigerate or freeze. Monitor patient for hypokalemia for first 48 hours, as anemia correct itself. Give potassium supplements, as needed.

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