APA Citation : Skalova, S., Rejtar, P. (2010). Safety profile of paediatric percutaneous ultrasonography-guided renal biopsies.

Singapore Med J, 51(6). Intended Audience : The target audience of the Singapore Med J are paediatrics who practising renal biopsies on patient with renal disease. Library Location : Library room at UiTM Puncak Alam. Safety profile of pediatric percutaneous ultrasonography-guided renal biopsies 1. Renal biopsy (RB) is a procedure to diagnose disease associated with renal. The complications are divided into two which are minor and major. Patient who do not need medical intervention is classified as minor whereas patient who need intervention is classified as major. Aim for renal biopsies are to ascertain the safety of RB, to detect the complication at age 1-19 years. Moreover, RB used to differentiate between radiographycontrolled and USG-guided percutaneous RB. 2. RB perform at 164 patients renal aged 1-19 years in 1997-2007. All patient must undergo routine pre-biopsy test. General anaesthasia is used for children under 12 years while local anaesthasia for children above 12 years. Observing of blood pressure, blood count and urine while biopsies is tested on inpatient basis. After 24 hours testing for USG-guided percutaneous RB, proceed with renal USG. Patient who is having haematuria and haematuria with proteinuria must perform biopsy. Renal USG result is recorded after it achieved USG-guided RB (n=139). For the overall result, p <0.05 used as indicator. 3. After the test has done, no major complication detected and minor complication resulting only in 39 patients. Furthermore, the majority complication is asymptomatic perirenal haematoma 21%, perirenal haematoma with abdominal pain is 1.4%, macroscopic haematoma is 4.2% : in two out of 27 patients after radiography controlled RB (7.4% subgroup; 1.2% total RB) and five out of 27 patients after USG-guided RB (3.6% subgroup; 3.0% total RB). Blood transfusion is not compulsory for any of these cases. Three patients with tubulointerstitial nephritis having minor post-biopsy complications. 4. Selection for renal biopsy helping in identifying renal problems. During undergoing the RB, the patient might have neither minor nor major complication. RB performed at 164 children (88 boys, 76 girls) in East Bohemia in 1997-2007. Their age is between 1-19 years old. All patient undergo routine pre-biopsy assessment. The result from renal USG is recorded after it reached at n=139. Using p <0.05 as the reference range for all results. No major complications shows but there are few minor complications detected. 5. From my point of view, I think RB is important to discover the complications in children and adolescent. In addition, RB is also useful to make the comparison that happen among patient and age or serum creatitine level. The RB are beneficial to detect renal disease. The safety profile of paediatric percutaneous ultrasonography-guided RB can be implemented by nephrologist whose doing research on RB.

Assignment Chemical pathology Ii Csi 252

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NURSHAHIRA BINTI SHAMSUDIN 2009274064 HS 111 (4A) EN. NORHISHAM BIN HARON

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