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Mechanical Separation Division

Data Sheet

C SC 20-06-476

Complete plant systems with automatic or manual SIP for down-stream processing of fermentation broths under sterile conditions

Fields

of

application

Biotechnology, pharmaceutical and food industry

Complete plant systems with automatic SIP

Typical

product

applications

.Starter cultures for the food and pharmaceutical sectors (e.g. lactic acid bacteria). .Recovery of biomass for pharmaceutical products (e.g. E-Coli). .Treatment of genetica1ly engineered micro-organisms and vaccines, made possible by the closed machine and insta1lation concept (biocontainment). .Gentle discharge of biomass with product-damaging ce1l constituents. This clarifier incorporates the very latest developments in centrifuge construction. The basic features of this new development are: .Clarifier bowl in sanitary design. .Cleaning-in-place -capacity of the clarifier . .Steam-sterilizable (SIP) up to 1.5 bar steam pressure (127 C). .Double-acting slide-ring packing as interface to the drive chamber. .Closed product feed and gentle treatment of shear-sensitive micro-organisms due to the hydrohermetic feed system. .No product contamination due to wear of lip seals and mechanical seals as is the case with hermetically sealed machines. .Low noise pollution due to double-walled coolable hood and solids collector suitable for connection to a closed sealing system up to 1 bar overpressure. .l'Hydrostop" system for controlled partial solids ejections.

.Photoelectric control using a turbidity measurement(28) to monitor the clarified liquid. If a pre-set turbidity level is exceeded, a signal is passed to the control unit (25) which then initiates the solids ejection process.Recommended for use with translucent liquids in which the solids content is not constant or if the throughput capacity varies. This monitoring system can be installed on every standard centrifuge.

The "hydrostop"
controlled partial

system tor
solids ejections

Bowl The product enters the bowl via the inlet (1) and is clarified in this disc stack (3). Centripetal pump (26) then conveys the clarified liquid under pressure to outlet (2), where it is discharged without foam. The separated solids collect in sediment holding space and are ejected periodically via ports (6). Operating water is used only during the actual process of ejection.

When product is processed, only partial solids ejections are performed. The solids ejections is initiated by the control unit. In the case of partial solids ejection, the hydraulically operated sliding piston (20) must be opened within as short a time as possible so as to ensure that the ejection ports are opend wide enough to allow unimpeded solids ejection. The sliding piston (20) is in closed position (left side of figure) when the closing chamber (21) is full. The annular valve (7) is hydraulically opened via valve (17) (right side og fig.). The operating-water flows from the closing chamber (21) into the storage chamber (10). When the storage chamber (10) is full, the flow of liquid from the closing chamber (21) will automatically stop, although the annular piston (7) is still open ("hydrostop" system). The bowl then opens and the solids are discharged rapidly through the ejection ports (6). The amount of solids ejected depends on the liquid level in the storage chamber (10) (controlled partial solids ejection). The amount of solids to be ejected can be pre-selected by partially filling the storage chamber (10) before the solids ejection is initiated. This is done by opening valve (16) which releases water into the storage chamber (10) through the nozzle (11). After the ejection process, the closing chamber (21) is topped up via valve (16). The annular valve (7) then closes. The storage chamber empties through discharge nozzle (8). This new "hydrostop" system reduces the actual solids ejection time to less than 1/10 second. In the case of solids which are difficult to eject, a longer solids ejection cycle is initiated after several partial solids ejections, which has the effect of flushing out remaining solids while the product feed is still open.

Automatic

solids

ejection

Bowl ejections are controlled automatically by control unit (25) The following operations are possible: .partial ejections .a combination of short and long partial ejections .Displacement of the liquid phase from the bowl before a total ejection .Flush ejection after every total ejection Total solids ejection sequence For total solids ejection, the closing chamber (21) is emptied via the annular valve (7) and the nozzle (8) by the addition of operating-water via valve (16). The sliding piston (20) remains open until the whole bowl contents have been ejected. The sliding piston (20) is then closed by supplying closing water via valve (17).

Control

systems
Feed and discharge

The following systems are available for controlling the automatic bowl ejections: .Time-dependent control to suit the particular operation. Recommended for use with products in which the solids content remains constant.

The produc t is fed into the centrifuge by means of a closed system of pipes. The clarified liquid is discharged foam-free and under pressure via a centripetal pump.

Hydrohermetic

product

feed

In this design the centrifuge is equipped with a hydrohermetic product feed (4). This new inlet system prevents shearing forces from acting bn the product when entering the bowl. Similar as with the fully hermetic design, the product stream is accelerated by the product itself in the filled bowl. This makes for gentle treatment and optimum clarifying efficiency, especially in the case of sensitive products and low throughput capacities.

The machine is driven by a three-phaseAC motor. Power is transferred to the bowl spindle via a centrifugal clutch and worm wheel gear. All bearings and the gear are splashlubricated from a central oil bath.

Monitoring .Lube oil sight glass .Temperature feeler and overcurrent protection in case of overload * Cooling The solids collector and the hood are of double-wall design for cooling the discharged solids (5, 9).

release for motor

.Speed measuring device .Vibration monitoring system * .Turbidity meter for monitoring the discharge * .Level probeB in the Bolids tank in case of enclosed Bolids discharge .Additional available charge parts atextra

Cleaning-in-place

(CIP)
Materials All parts coming into contact with the produc t are made of austenitic Cr-Ni-Mo stainless steel or, in the case of highly stressed bowl parts, of soft martensitic Cr-Ni-Mo steel or duplex alloys. The gaskets are made of ethylene-propylene-dienecaoutchouc (EPDM) and Polyamid.

Once the centrifugation process has been completed, the machine can be cleaned-in-place.The cleaning solution is circulated round the centrifuge and the connected system. Total ejections are initiated during CIP manua1ly or automatica1lyon the control unit via an extemal CIP control.

Steri

I ization

The stationary installation is sterilized with hot steam (127 C) under an excess pressure of 1.5 bar. The duration of sterilization is dependent on the nature of the bacteria and the number of germs. Experience suggests a time between 60 minutes. The condensate is conveyed from the lowest point of the system to the killing line. Following sterilization, the whole system is blanketed with sterile air until the next product run.

Assembly

and dismantling
the bowl are

Special tools for installing and removing included in the supply schedule.

Frame

and

drive

The cast-iran frame is equipped with brakes, a rev indicatar and an aillevel sight glass.

Additional (available

equipment at extra charge)

Camplete plant systems with autamatic ar manual SIP

Technical

data
8340 8 min 1

Bowl Speed Total bowl volume Volumen of sediment holding space (with large disc stack) Max. pressure produced by centripetal pump Three-phase AC motor Motor power Speed at 50 Hz Speed at 60 Hz Type Type of protection

4 1 4 bar 11 1500 1800 IMB5 IP55


kW min-l min-1

Weights Complete plant

net 1900 kg grass 2500 kg

Capacity Rated capacity with one channel centripetal pump with two channel centripetal pump

1400 l/h 2800 l/h

The rated capacity indicates the maximum throughput rate of the bowl. The actual operating capacity is usually lower. It depends on the particular product and on the required level of clarification.

Westfalia
Mechanical Division Separation

Separator

AG

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Westfalia Separator AG. Separation Technology .Werner-Habig-Strae 1 .D-59302 Oelde (F.R. Germany) Tel.: +49 (0) 2522/77-0. Fax: +49 (0) 2522/77-2488. Internet: http://www.westfalia-separator.com

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9997-0516-000/0597

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Subiect ta madificatian

Printed

in GermaJ