Академический Документы
Профессиональный Документы
Культура Документы
Thymus soft, bilobed organ within the mediastinum. it slowly shrinks after puberty. its composed of lymphatic tissue subdivided into lobules lobules conatin lymphocytes T lymphocytes leave the thymus and provide immunity secretes thymosins, which stimulate maturation of T lymphocytes Spleen upper left portion of the abdominal cavity resembles a large lymph node encapsulated and subdivided into lobules by VT spaces in splenic lobules are filled with blood filters foreign particles and damaged RBCs from the blood, contains many macrophages and lymphocytes
22. Review the origin of T cells and B cells. (p. 628) T cells originate in the thymus. B cells are those processed in another part of the body, i.e. the fetal liver. 25. Define cytokine. (p. 630) Type of protein secreted by a T lymphocyte that attacks viruses, virally infected cells, and cancer cells 28. Explain the function of plasma cells. (p. 632) Type of antibody-producing cell that forms when activated B cells proliferate 31. Match the types of antibodies with their function and/or where each is found. (p. 635) 1. Associated with allergic reactionsIgE 2. Important in B cell activation, on surfaces of most B cellsIgD 3. Activates complement, anti-A and anti-B in bloodIgM 4. Effective against bacteria, viruses, toxins in plasma and tissue fluidsIgG 5. In exocrine secretions, including breast milkIgA
Primary immune response B cells or T cells first encountering an antigen for which they are specialized to react constitutes a p.i.r. Secondary immune response occurs rapidly as memory cells respond to subsequent exposure to an antigen
35. Contrast active and passive immunity. (p. 638)
Active immunity a person who encounters a pathogen and has a primary immune response develops natarullay a.i. Passive Immunity when antinodies pass through a placental membrane from a pregnant woman to her fetus, the fetus develops naturally acquired p.i.
36. Define vaccine. (p. 638) Preparation that includes antigens used to stimulate an immune response to prevent an infectious disease 37. Explain how a vaccine produces its effect. (p. 638) A vaccine contains bacteria or viruses that have been killed or weakened so they cannot cause a serious infection; or it may contain a toxin of an infectious organism that has been chemically altered to destroy its toxic effects. The antigens present still retain the characteristics needed to simulate a primary immune response. 38. Describe how a fetus may obtain antibodies from maternal blood. (p. 638) Receptor-mediated endocytosis utilizing receptor sites on cells of the fetal yolk sac transfers IgG molecules to the fetus. 39. Explain the relationship between an allergic reaction and an immune response. (p. 639) Allergic or hypersensitivity reactions are excessive misdirected immune responses that may change tissues. 40. Distinguish between an antigen and an allergen. (p. 639) Antigen Substance that stimulate cells to produce antibodies
41. Describe how an immediate-reaction allergic response may occur. (p. 639) Occurs within minutes after contact. Persons with this type of allergy have inherited the tendency to overproduce IgE antibodies in response to certain antigens 42. List the major events leading to a delayed-reaction allergic response. (p. 641) It results from repeated exposure of the skin to certain chemical substances. As a consequence of these repeated contacts, the foreign substance and a large number of T cells collect in the skin and eventually activate the T cells. Their actions and the actions of macrophages they attract cause the release of various chemical factors. This causes eruptions and inflammation of the skin. It is called delayed since it takes about forty-eight hours to occur. 43. Explain the relationship between tissue rejection and an immune response. (p. 641) A transplant recipients immune system may react against the donated tissue in a tissue rejection reaction.
4.