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Topics Covered in class: Genetics - inheritance, variation Speciation Phylogeny, systematics Review: Issues Darwin saw with his theory: 1. ________________________ 2. Differs due to environments and characteristics of different species
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Inheritance ____________________ - theory Darwin believed in (opposite of the Germ Plasm Theory) What is the problem with blending inheritance?
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The Modern Synthesis by R.A. Fisher Natural selection acts on individuals but entire populations evolve Evolution - change in _____________________ in populations over time New field of population genetics
Mutations - cause of genetic variation with an average of 1 in 100,000 genes per generation.
_______________ - single base nucleotide substitution in the mRNA sequence that can be nonsense, missense or silent.
Additions or subtractions - when three base nucleotides are ____________ or ____________ from the mRNA sequence, which can be minor or detrimental to the protein.
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Hardy Weinberg Principle - mathematical model of a population that's not evolving. Hardy Weinberg Equation
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The Five Conditions of Hardy Weinberg Principle 1. 2. 3. 4. 5. Extremely large populations, no genetic drift No mutations
Genetic Drift - change in the _______________ of alleles in a population over time through ___________________. Define Founder Effect
Biological Species Concept A __________ is a population whose members have the potential to _____________ and produce ___________ offspring.
Name 2 other species concepts of the 4 discussed in lecture 1. 2. 3. _______________________ _______________________ _______________________
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For pre-mating, post-mating prezygotic, and post-mating post-zygotic, name the kinds of isolating mechanisms that prevent crosses from being fertile.
_______________ ______________ - isolation of the same species in two different places to produce two different species. Polyploidy - errors in cell division resulting in more than two pairs of homologous chromosomes Autopolyploidy polyploids with multiple chromosome sets from a single species
_______________ ______________ - the creating of a new species that inhabit the same geographic region as the ancestral species
Hybrid zone - when two interbreeding species meet and reproduce, relatively rare due to low fertility
The time it takes for speciation is variable, it can happen as quickly as ________ years or ______________ years.
Systematics - _________________
Phylogeny tree
Polyphyletic
Words you should know: ____________ - monophyletic group ____________ - trait present in a clades ancestor ____________ - trait derived with a clade
Note: Allele frequencies: - frequency of the dominant allele in the population - frequency of the recessive allele in the population
Genotype frequencies: percentage of homozygous dominant individuals percentage of homozygous recessive individuals percentage of heterozygous individuals 1. A sampling of a population showed that the percentage of homozygous recessive (aa) individuals is 16%. Calculate the following: a. Allelic frequency of the a b. Genotypic frequency of AA c. Genotypic frequency of Aa Randomly mating butterflies contain 45% white butterflies, which is caused by homozygous recessive trait (dd). Calculate the allelic and genotypic frequencies. The blood type of 1000 individuals was taken. Blood type A and B exhibit co-dominance (AB). Blood type Genotype Number of Individuals A AA 490 AB AB 420 B BB 90 a. b. Calculate the allele frequencies. What is the probability of each genotype resulting from every potential cross: AAxAA, AAxAB, AAxBB, ABxAB, ABxBB, BBxBB.
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