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IN COMMUNITY
SECONDARY PREVENTION
HEALTH PROMOTION
(A)HEALTH EDUCATION:
‘ONLY VACCINE’
ROLE OF MEDIA/ RADIO/ ELECTRONIC
MAILING LISTS.
SHOULD COVER:
1. CAUSE, EFFECT, INCURABILITY
2. MODE OF TRANSMISSION
3. A,B,C + ‘HOPE’
4. USAGE OF DISPOSABLE SYRINGES
5. AVOID NEEDLE SHARING
(B) EXAMINATION AND REHABILITATION
OF PROSTITUTES.
(C) CONTROL OF STD’S AND DRUG ABUSE.
Why Mailing lists are more popular?
• Easy to set up
• Setting up is free/ low cost/ no full time staff
• Information goes to individual subscribers.
• Fast and economical
OTHER MEASURES:
Better nutrition
Prevention, detection and
early treatment of STD’s
Marriage counselling
SECONDARY PREVENTION
1. HIV CARRIERS:
Informed about long IP.
Educated not to share needles/ syringes/
donate blood
To keep cuts/ bruises covered with plaster.
2. TREATMENT:
(A)DRUGS:
(A)NRTI’s: (B)NNRTI’s:
Zidovudine: 500-600mg (O) Nevirapine: 200mg OD x 2
in 2 or 3 divided doses. weeks; then BD. SE: rash
SE: Anemia. Delaviridine: 400mg TDS.
Didanosine: 12-300mg (O) SE: rash.
BD. SE: PN, hep, (C)PI:
pancreatitis. Saquinavir: 600mg TDS. SE:
Stavudine: 40mg BD(O). SE: GI distress.
same. Ritonavir: 600mg BD or
Zalcitabine: 0.375 – 0.75mg 400mg BD in combination
(O) TDS. SE: PN, with other PI’s. SE: GIT.
aphthous ulcers. Indinavir: 800mg TDS. SE:
Lamivudine: 150mg BD. SE: Kidney stones.
PN, rash Nelfinavir: 750mg TDS. SE:
dairrhoea.
EVOLUTION OF THERAPY:
Monotherapy – resistance.
2 drug combinations: ZDV + 3TC; ZDV + ddl;
Saquinavir and Ritonavir.
Benefits not persistent and resistance.
Triple therapy: one PI (Indinavir) and 2 NRTI’s
(ZDV and 3TC).
PEP:
• AZT (200mg TDS) + 3TC (150mg BD) x 4 weeks
• Advanced AIDS: PI (nelfinavir) added – 750mg
TDS.
• Failed on AZT/3TC; stavudine + ddl used instead.
OPPORTUNISTIC INFECTIONS:
P. carinii pneumonia: <200cells/ul; trimethoprim-
sulphamethoxazole, dapsone.
M. avium: Rifabutin.
M. tuberculosis: 300mg INH daily x 9 months..
Kaposi’s sarcoma: interferon/ chemotherapy/
radiation.
CMV retinitis: ganciclovir
Cryptococcal meningitis: fluconazole.
Esophageal candidiasis: fluconazole/ ketoconazole
HS: acyclovir
• REFERENCES:
Oxford Book on Community health
Principles of Community Medicine (Dr.
Sridhar Rao)
Park and Park