Group No.

3: Submitted On: September 28, 2006

David Earl Dadivas
Rose Ann Esteban
Karyl Sabrina Javellana
Methence Tayuba

ACTIVITY NO. ___

MUSCULAR TISSUE

STUDY FOCUSING QUESTIONS

1. Compare and contrast the following by tabulating the required information:

a.
Skeletal/
Cardiac Muscle Smooth Muscle
Striated Muscle
Fusiform or
spindle-shaped
cells with fine
tapering ends
and a wider
50-60 um
15 um dia. by central region
diameter and up
100um; in which the
to 10 cm long;
Size and Shape Long and oval nucleus is
Long and
of Cells branching; situated; vary
cylindrical in
smaller than in size from 20
shape
skeletal muscle um (sm.
vessels) to
400-500 um
(uterus), round
shape during
contraction
Large number of Myofibrils are
parallel fibers arranged in
are grouped into parallel bundles Form small
Orientation of fascicles, with a small fascicles with
Cells associated in amount of meager
different sarcoplasm perimysium.
patterns to form separating each
the muscles. bundle.
Presence of
Yes Yes No
Striations
Nucleus is
Multinucleated; centrally
Number and located Long, centrally located and
Location of peripherally just positioned either
Nuclei beneath the nucleus elongated or
sarcolemma elliptical

Composition Triads Dyads Caveolae

and
Arrangement
of Intracellular
Membrane
Systems
Postion of T- Occur only over
tubules in the Z-lines of T-tubules are
Transeverse
Relation to the ends of absent
Bands sarcomeres.
Presence of
Motor End Yes No No
Plates
Type of Motor
Voluntary Involuntary Involuntary
Control
Presence of
Distinct Yes No No
Myofibrils
Presence of
Intercalated
No Yes No
Disks

Scanty amount
Abundant
of areolar CT
areolar CT
containing
contain blood Richly supplied
blood vessels is
vessels with small blood
Vascularity seen between
intervening vessels and
units;
between nerve plexuses
Not as vascular
sections of
as skeletal or
muscle fibers.
cardiac muscle.

b.
Thin Filaments
Proteins Actin, Tropomyosin,
Troponin (TnC, TnT, TnI)
Arrangement of Troponin molecules are
Subunits attached at specific
intervals along the
actin myofilaments.
Tropomyosin filaments
are located along the
groove between the
twisted strands of actin
myofilament subunits.
Location I-band of sarcomere
Thick Filaments
Myosin
Myosin resembles a golf
club. It’s thin shaft is
composed of the Light
Meromyosin (LMM)
chain and the Heavier
Head (HMM) chain has
actin and ATP-binding
sites necessary for
contraction.
A-band of sarcomere

c.
Red Muscle White Muscle
Myoglobin Content Rich myoglobin Low myoglobin
content content
Cytochrome Content Rich in mitochondria Sparse mitochondria
Rate of Contraction Slow and steady Quick and forceful
Main Source of
ATP ATP
Energy
Capacity for
Yes No
Sustained Activity
Location Predominant in
Predominant in
postural muscles and
extraocular muscles
limbs

2. Sketch the following and label the parts:

a) organization of muscle tissue: muscle, fascicles, CT membrane
coverings, myofibrils, myofilaments

b) relaxed and contracted sarcomeres (l.s.): A, I, H bands; Z and M lines

c) spatial and structural relationships of the actin-troponin-tropomyosin

complex with myosin chains: G-actin, F-actin, HMM, LMM, TnC, TnI,
TnT, tropomyosin, ATPase

d) triad and dyad of skeletal and cardiac muscle: sarcoplasmic reticulum,

terminal cisternae, T-tubules, sarcomere bands and lines

e) myoneural junction: terminal bouton, synaptic vesicles, presynaptic

and postsynaptic membranes, junctional folds, primary and secondary
synaptic clefts, teloglial cells, basal lamina

3. Beginning with an impulse traveling down the axon of a motor neuron, list
the events of skeletal muscle stimulation, contraction, and relaxation.