Clinical Medications Worksheets

Generic Name Trade Name Classification Dose Route Time/frequency

enoxaparin Lovenox Anticoagulants, antithrombotics
Peak Onset Duration
Unknown unknown 12 hrs
Why is your patient getting this medication
Prevention of thrombus formation. Systemic anticoagulation
for prevention of ischemic or thrombotic events (e.g., MI,
stroke)
Mechanism of action and indications
(Why med ordered)
Systemic anticoagulation
Potentiates the inhibitory effect of antithrombin on factor Xa
and thrombin
Interactions with other patient drugs, OTC or herbal
medicines (ask patient specifically)
Plavix: Drugs that can affect hemostasis such as dextran,
platelet inhibitors, thrombin inhibitors, thrombolytic agents, or occurs, assess for hemorrhage
other anticoagulants may potentiate the risk of bleeding
complications associated with the use of a low molecular
weight heparin (LMWH), heparinoid, or fondaparinux. In
patients receiving neuraxial anesthesia or spinal puncture, the
risk of developing an epidural or spinal hematoma during
LMWH, heparinoid, or fondaparinux therapy may also be
increased by the concomitant use of other drugs that affect
coagulation. The development of epidural and spinal
hematoma can lead to long-term or permanent paralysis.
ASA: In patients receiving neuraxial anesthesia or spinal
puncture, the risk of developing an epidural or spinal
hematoma during low molecular weight heparin (LMWH) or
heparinoid therapy may be increased by the concomitant use of
other drugs that affect coagulation, including nonsteroidal anti-
inflammatory drugs (NSAIDs). The development of epidural
and spinal hematoma can lead to long-term or permanent
paralysis.
40 mg SQ qid
Normal dosage range
40mg SQ daily
For IV meds, compatibility with IV drips and/or solutions
N/A
Nursing Implications (what to focus on)
Contraindications/warnings/interactions
Hypersensitivity, uncontrolled bleeding, GI
bleeding/ulceration/pathology. Geriatric patients (enoxaparin
elimination prolonged). Retinopathy (hypertensive or diabetic).
Untreated hypertension. History of congenital or acquired bleeding
disorder. Recent history of ulcer disease. Hemorrhagic stroke.
Common side effects
Dizziness, headache, insomnia, constipation, N/V, urinary retention,
bleeding, anemia, thrombocytopenia
Lab value alterations caused by medicine
Reversible increase in liver enzymes, monitor CBC, platelet count and
, monitor closely if thrombocytopenia occurs, if decrease in hematocrit
Be sure to teach the patient the following about this medication
Advise patient to report any symptoms of unusual bleeding or bruising,
dizziness, itching, rash, fever, swelling, or difficulty breathing to health
care professional immediately. Instruct patient not to take aspirin,
naproxen, or ibuprofen without consulting health care professional
while on enoxaparin therapy.

Nursing Process- Assessment Assessment Evaluation

(Pre-administration assessment)
Assess for signs and symptoms of bleeding and
hemorrhage (bleeding gums; nosebleed; unusual
bruising; black, tarry stools; hematuria; fall in
hematocrit or blood pressure; guaiac-positive
stools), assess for signs and symptoms of
thrombosis, observe injection sites for hematomas.
Why would you hold or not give this med?
Hypersensitivity (chills, fever, urticaria).
Assess for signs of bleeding and hemorrhage
(bleeding gums; nosebleed; unusual bruising;
black, tarry stools; hematuria; fall in
hematocrit or blood pressure; guaiac-positive
stools); bleeding from surgical site. Notify
physician or other health care professional if
these occur.
Check after giving
Unusual bleeding or hemorrhage.
Prevent DVT/clot formation.
Observe injection sites for
hematomas, ecchymosis, or
inflammation.