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DRUG STUDY Name of Patient: R.B. Age: 5 mo.

Diagnosis: SVI (Systemic Viral Infection)

Mechanism of Factor: -Depress the CNS, probably by potentiating GABA, an inhibitory neurotransmitter. - Produces skeletal muscle relaxation by inhibiting spinal polysynaptic afferent pathways. - Has anticonvul-sant properties due to enhanced presynaptic inhibition.Therapeutic effects: (1) Relief of Anxiety (2) Sedation (3) Amnesia (4) Skeletal muscle relaxant (5) Decreased seizure activity

Magbanua, Jonalin T. BN2-B

Name of Drug: Diazepam

Dosage: 1.8 mg

Indications: -Adjunct in the management of: 1) Anxiety 2) Preoperative sedation 3) Conscious sedation - Provides light anesthesia and anterograde amnesia - Treatment of status epilepticus/ uncontrolled seizures - Skeletal muscle relaxant - Management of the symptoms of alcohol withdrawal

Contraindications: - Hypersensitivity - Cross-sensitivity with other benzodiazepines may occurs - Comatose patients - Pre-existing CNS depression - Uncontrolled severe pain - Use cautiously in: 1) Hepatic dysfunction 2) Severe renal impairment 3) History of suicide attempt or drug dependence

Adverse Reaction:
Adverse Effects

Nursing Responsibilities:

Generic Name: Diazepam

Route: Direct IV

Brand Name: Valium, Diastat

Frequency: PRN


Antianxiety agents, anticonvulsants, sedative/hyptonics, skeletal muscle relaxants (centrally acting)

- Monitor BP, PR,RR prior to periodically throughout therapy and frequently during IV therapy. - CNS: dizziness, - Assess IV site frequently during drowsiness, lethargy, administration, diazepam may cause hangover, headache, phlebitis and venous thrombosis. depression - Observe and record intensity, - EENT: blurred vision duration and location of seizure - RESP: respiratory activity. The initial dose of diazepam depression offers seizure control for 15-20 min - CV: hypotension - GI: constipation, after administration. diarrhea, nausea, vomiting - Effectiveness of therapy can be - SKIN: rashes demonstrated by decrease anxiety - LOCAL: pain (IM), level; control of seizures; decreased phlebitis (IV), venous tremulousness. thrombosis - MISC: physical & psychological Nursing Interventions dependence, tolerance

-Assess baseline vital signs Assess blood pressure, pulse and -hives or other swelling in respiration if IV administration. - Provide frequent sips of water the face, lips, tongue or for dry mouth. throat or difficulty breathing or swallowing. - Provide fluids and fibre for constipation. - Evaluate therapeutic response, mental state and physical dependency after long-term use.
Allergic reaction: